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List of works by Salvatore Lopez

A Predictive Score for Secondary Cytoreductive Surgery in Recurrent Ovarian Cancer (SeC-Score): A Single-Centre, Controlled Study for Preoperative Patient Selection.

scientific article published on 26 March 2015

Adjuvant chemotherapy vs. observation in stage I clear cell ovarian carcinoma: A systematic review and meta-analysis

scientific article published on 21 January 2020

Afatinib demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro and in vivo.

scientific article

Age-specific predictors of cervical dysplasia recurrence after primary conization: analysis of 3,212 women

scientific article published on 01 September 2020

Anterior colporrhaphy plus inside-out tension-free vaginal tape for associated stress urinary incontinence and cystocele: 10-year follow up results.

scientific article

Antiangiogenics and immunotherapies in cervical cancer: an update and future's view

scientific article published on 5 May 2017

Cervical carcinomas that overexpress human trophoblast cell-surface marker (Trop-2) are highly sensitive to the antibody-drug conjugate sacituzumab govitecan

scientific article published on 22 January 2020

Clostridium perfringens enterotoxin (CPE) and CPE-binding domain (c-CPE) for the detection and treatment of gynecologic cancers

scientific article published on April 2015

Clostridium perfringens enterotoxin C-terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy-resistant ovarian cancer

scientific article published on 9 June 2015

Dacomitinib (PF-00299804), a second-generation irreversible pan-erbB receptor tyrosine kinase inhibitor, demonstrates remarkable activity against HER2-amplified uterine serous endometrial cancer in vitro

scientific article

Dual CCNE1/PIK3CA targeting is synergistic in CCNE1-amplified/PIK3CA-mutated uterine serous carcinomas in vitro and in vivo

scientific article published on 28 June 2016

Dual HER2/PIK3CA Targeting Overcomes Single-Agent Acquired Resistance in HER2-Amplified Uterine Serous Carcinoma Cell Lines In Vitro and In Vivo

scientific article

Dual-Targeting Nanoparticles for In Vivo Delivery of Suicide Genes to Chemotherapy-Resistant Ovarian Cancer Cells

scientific article published on 12 December 2016

Efficacy of neratinib in the treatment of HER2/neu-amplified epithelial ovarian carcinoma in vitro and in vivo

scientific article

Further insight into prognostic factors in endometrial cancer: the new serum biomarker HE4.

scientific article published on 28 November 2016

Gynecologic oncology at the time of COVID-19 outbreak

scientific article published on 27 May 2020

HER2/neu gene amplification determines the sensitivity of uterine serous carcinoma cell lines to AZD8055, a novel dual mTORC1/2 inhibitor.

scientific article published on 4 September 2013

Hemorrhagic cystitis in pregnancy: Case report and review of the literature.

scientific article published on 23 August 2017

Hormone replacement therapy in cancer survivors: Utopia?

scientific article published on 8 February 2018

Impact of COVID-19 in gynecologic oncology: a Nationwide Italian Survey of the SIGO and MITO groups

scientific article published on 01 November 2020

Implementing the Risk of Endometrial Malignancy Algorithm (REM) adding obesity as a predictive factor: Results of REM-B in a single-center survey

scientific article published on 7 April 2018

Inhibition of BET Bromodomain Proteins with GS-5829 and GS-626510 in Uterine Serous Carcinoma, a Biologically Aggressive Variant of Endometrial Cancer

scientific article published on 25 June 2018

Management of endometrial, ovarian and cervical cancer in the elderly: current approach to a challenging condition

scientific article published on 12 December 2018

Management of gynecological cancer in pregnant patients

scientific article published on 11 October 2018

May intraperitoneal irrigation with Betadine improve cesarean delivery outcomes? Results of a 6 years' single centre experience.

scientific article

Mutational landscape of primary, metastatic, and recurrent ovarian cancer reveals c-MYC gains as potential target for BET inhibitors

scientific article published on 24 December 2018

Mutational landscape of uterine and ovarian carcinosarcomas implicates histone genes in epithelial-mesenchymal transition

scientific article published on 10 October 2016

Neratinib shows efficacy in the treatment of HER2 amplified carcinosarcoma in vitro and in vivo.

scientific article

Neratinib shows efficacy in the treatment of HER2/neu amplified uterine serous carcinoma in vitro and in vivo

scientific article published on 12 August 2014

Novel targeted therapies in ovarian and uterine carcinosarcomas

scientific article published on 01 June 2018

Oncogenic PIK3CA gene mutations and HER2/neu gene amplifications determine the sensitivity of uterine serous carcinoma cell lines to GDC-0980, a selective inhibitor of Class I PI3 kinase and mTOR kinase (TORC1/2).

scientific article published on 24 July 2013

Ovarian cancer relapse: From the latest scientific evidence to the best practice

scientific article published on 29 May 2019

PARP-1 activity (PAR) determines the sensitivity of cervical cancer to olaparib

scientific article published on 18 August 2019

PI3K oncogenic mutations mediate resistance to afatinib in HER2/neu overexpressing gynecological cancers

scientific article published on 07 January 2019

PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas

scientific article

PIK3CA oncogenic mutations represent a major mechanism of resistance to trastuzumab in HER2/neu overexpressing uterine serous carcinomas

scientific article published on 01 December 2015

Patients treated with neoadjuvant chemotherapy + radical surgery + adjuvant chemotherapy in locally advanced cervical cancer: long-term outcomes, survival and prognostic factors in a single-center 10-year follow-up

scientific article published on 30 August 2016

Polymerase ε (POLE) ultra-mutated tumors induce robust tumor-specific CD4+ T cell responses in endometrial cancer patients.

scientific article published on 27 April 2015

Polymerase ε (POLE) ultra-mutation in uterine tumors correlates with T lymphocyte infiltration and increased resistance to platinum-based chemotherapy in vitro.

scientific article published on 25 November 2016

Postpartum perineal pain: may the vaginal treatment with CO2 laser play a key-role in this challenging issue?

scientific article published on 17 June 2019

Preeclampsia and the challenge of early prediction: reality or utopia? State of art and critical review of literature

scientific article published on 10 September 2018

Prevalence and role of HER2 mutations in cancer

scientific article published on 02 April 2019

Role of human epididymis protein 4 (HE4) in detecting recurrence in CA125 negative ovarian cancer patients

scientific article published on 16 April 2019

Role of paroxetine in the management of hot flashes in gynecological cancer survivors: Results of the first randomized single-center controlled trial

scientific article published on 14 October 2016

SYD985, a Novel Duocarmycin-Based HER2-Targeting Antibody-Drug Conjugate, Shows Antitumor Activity in Uterine Serous Carcinoma with HER2/Neu Expression

scientific article published on 2 June 2016

Sacituzumab govitecan, an antibody-drug conjugate targeting trophoblast cell-surface antigen 2, shows cytotoxic activity against poorly differentiated endometrial adenocarcinomas in vitro and in vivo

scientific article published on 14 January 2020

Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE), is highly active against primary uterine serous papillary carcinoma cell lines in vitro.

scientific article

Solitomab, an EpCAM/CD3 bispecific antibody construct (BiTE®), is highly active against primary uterine and ovarian carcinosarcoma cell lines in vitro

scientific article

Solitomab, an epithelial cell adhesion molecule/CD3 bispecific antibody (BiTE), is highly active against primary chemotherapy-resistant ovarian cancer cell lines in vitro and fresh tumor cells ex vivo

scientific article

T-DM1, a novel antibody-drug conjugate, is highly effective against primary HER2 overexpressing uterine serous carcinoma in vitro and in vivo

scientific article

T-DM1, a novel antibody-drug conjugate, is highly effective against uterine and ovarian carcinosarcomas overexpressing HER2.

scientific article

Target Therapies for Uterine Carcinosarcomas: Current Evidence and Future Perspectives.

scientific article

Taselisib, a selective inhibitor of PIK3CA, is highly effective on PIK3CA-mutated and HER2/neu amplified uterine serous carcinoma in vitro and in vivo

scientific article

Ten years of HPV vaccines: State of art and controversies.

scientific article published on 2 April 2016

The Role of HE4, a Novel Biomarker, in Predicting Optimal Cytoreduction After Neoadjuvant Chemotherapy in Advanced Ovarian Cancer.

scientific article published on 13 April 2017

The Role of Oxidative Stress and Membrane Transport Systems during Endometriosis: A Fresh Look at a Busy Corner.

scientific article

The role of macroplastique implantation in the management of occult urinary stress incontinence

scientific article published on 21 April 2018

The role of novel biomarker HE4 in the diagnosis, prognosis and follow-up of ovarian cancer: a systematic review

scientific article published on 31 July 2017

Undescended or absent ovary without uterine anomalies: systematic review and a single center's experience.

scientific article published on February 2017

Undescended or absent ovary without uterine anomalies: systematic review and a single-center experience

scientific article

Validation of REM score to predict endometrial cancer in patients with ultrasound endometrial abnormalities: results of a new independent dataset.

scientific article published on 7 April 2017

Whole-exome sequencing of cervical carcinomas identifies activating ERBB2 and PIK3CA mutations as targets for combination therapy

scientific article published on 17 October 2019

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