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List of works by Antonio Cigliano

4EBP1/eIF4E and p70S6K/RPS6 axes play critical and distinct roles in hepatocarcinogenesis driven by AKT and N-Ras proto-oncogenes in mice

scientific article published on 25 November 2014

A functional mammalian target of rapamycin complex 1 signaling is indispensable for c-Myc-driven hepatocarcinogenesis.

scientific article published on 30 March 2017

A proteomic approach to differentiate histologically classified stable and unstable plaques from human carotid arteries

scientific article

Activation of β-catenin and Yap1 in human hepatoblastoma and induction of hepatocarcinogenesis in mice.

scientific article published on 14 May 2014

Association between Human Plasma Chondroitin Sulfate Isomers and Carotid Atherosclerotic Plaques

scientific article

Both de novo synthetized and exogenous fatty acids support the growth of hepatocellular carcinoma cells.

scientific article published on 6 June 2016

Central role of mTORC1 downstream of YAP/TAZ in hepatoblastoma development

scientific article published in September 2017

Cholesterol biosynthesis supports the growth of hepatocarcinoma lesions depleted of fatty acid synthase in mice and humans

scientific article published on 06 April 2019

Co-activation of AKT and c-Met triggers rapid hepatocellular carcinoma development via the mTORC1/FASN pathway in mice.

scientific article published on 9 February 2016

Combined CDK4/6 and Pan-mTOR Inhibition Is Synergistic Against Intrahepatic Cholangiocarcinoma

scientific article published on 03 July 2018

Deregulated c-Myc requires a functional HSF1 for experimental and human hepatocarcinogenesis.

scientific article published on 3 October 2017

Differential distribution of structural components and hydration in aortic and pulmonary heart valve conduits: Impact of detergent-based cell removal.

scientific article published on 8 July 2010

Differential requirement for de novo lipogenesis in cholangiocarcinoma and hepatocellular carcinoma of mice and humans.

scientific article published on 22 February 2016

Efficacy of MEK inhibition in a K-Ras-driven cholangiocarcinoma preclinical model.

scientific article published on 18 January 2018

Fine structure of glycosaminoglycans from fresh and decellularized porcine cardiac valves and pericardium.

scientific article published on 22 February 2012

Focal adhesion kinase activation limits efficacy of Dasatinib in c-Myc driven hepatocellular carcinoma

scientific article published on 28 October 2018

Functional crosstalk between AKT/mTOR and Ras/MAPK pathways in hepatocarcinogenesis: implications for the treatment of human liver cancer.

scientific article published on 6 June 2013

Functional role of SGK3 in PI3K/Pten driven liver tumor development

scientific article published on 11 April 2019

Hepatocellular glycogenotic foci after combined intraportal pancreatic islet transplantation and knockout of the carbohydrate responsive element binding protein in diabetic mice.

scientific article published in November 2017

Hippo cascade controls lineage commitment of liver tumors in mice and humans

scientific article published on 26 January 2018

Inactivation of Spry2 accelerates AKT-driven hepatocarcinogenesis via activation of MAPK and PKM2 pathways.

scientific article published on 19 May 2012

Inactivation of fatty acid synthase impairs hepatocarcinogenesis driven by AKT in mice and humans

scientific article published on 14 October 2015

Inhibition of MELK Protooncogene as an Innovative Treatment for Intrahepatic Cholangiocarcinoma

scientific article published on 18 December 2019

Jagged 1 is a major Notch ligand along cholangiocarcinoma development in mice and humans

scientific article published on 05 December 2016

Loss of Fbxw7 synergizes with activated Akt signaling to promote c-Myc dependent cholangiocarcinogenesis

scientific article published on 11 June 2019

Loss of Pten synergizes with c-Met to promote hepatocellular carcinoma development via mTORC2 pathway

scientific article

MEK inhibition suppresses K-Ras wild-type cholangiocarcinoma in vitro and in vivo via inhibiting cell proliferation and modulating tumor microenvironment

scientific article published on 11 February 2019

MicroRNA-203 impacts on the growth, aggressiveness and prognosis of hepatocellular carcinoma by targeting MAT2A and MAT2B genes

article

Modification of the base excision repair enzyme MBD4 by the small ubiquitin-like molecule SUMO1

scientific article published on 08 August 2019

Molecular and metabolic changes in human liver clear cell foci resemble the alterations occurring in rat hepatocarcinogenesis.

scientific article

Oncogene dependent requirement of fatty acid synthase in hepatocellular carcinoma

scientific article published on 24 January 2017

Oncogene-dependent addiction to carbohydrate-responsive element binding protein in hepatocellular carcinoma

scientific article published on 18 July 2018

Oncogenic potential of N-terminal deletion and S45Y mutant β-catenin in promoting hepatocellular carcinoma development in mice

article

PI3K/AKT/mTOR-dependent stabilization of oncogenic far-upstream element binding proteins in hepatocellular carcinoma cells.

scientific article published on 14 January 2016

Pan-mTOR inhibitor MLN0128 is effective against intrahepatic cholangiocarcinoma in mice.

scientific article published on 18 July 2017

Pathogenetic, Prognostic, and Therapeutic Role of Fatty Acid Synthase in Human Hepatocellular Carcinoma

scientific article published on 11 December 2019

Pivotal Role of Fatty Acid Synthase in c-MYC Driven Hepatocarcinogenesis

scientific article published on 11 November 2020

Plasma levels of C-reactive protein, leptin and glycosaminoglycans during spontaneous menstrual cycle: differences between ovulatory and anovulatory cycles

scientific article published on 20 March 2010

Quantification of liver proton-density fat fraction in 7.1T preclinical MR systems: Impact of the fitting technique.

scientific article

Role of the Notch signaling in cholangiocarcinoma.

scientific article published on 22 March 2017

SNAI1 Promotes the Cholangiocellular Phenotype, but not Epithelial-Mesenchymal Transition, in a Murine Hepatocellular Carcinoma Model

scientific article published on 05 August 2019

TEA Domain Transcription Factor 4 Is the Major Mediator of Yes-Associated Protein Oncogenic Activity in Mouse and Human Hepatoblastoma

scientific article published on 19 February 2019

TGF-β as Multifaceted Orchestrator in HCC Progression: Signaling, EMT, Immune Microenvironment, and Novel Therapeutic Perspectives

scientific article published on 26 December 2018

Tankyrase inhibitors suppress hepatocellular carcinoma cell growth via modulating the Hippo cascade.

scientific article published on 6 September 2017

The Epidermal Growth Factor Receptor (EGFR) Inhibitor Gefitinib Reduces but Does Not Prevent Tumorigenesis in Chemical and Hormonal Induced Hepatocarcinogenesis Rat Models

scientific article (publication date: 23 September 2016)

The mTORC2-Akt1 Cascade Is Crucial for c-Myc to Promote Hepatocarcinogenesis in Mice and Humans

scientific article published on 21 June 2019

Transcriptomic and Proteomic Analysis of Clear Cell Foci (CCF) in the Human Non-Cirrhotic Liver Identifies Several Differentially Expressed Genes and Proteins with Functions in Cancer Cell Biology and Glycogen Metabolism

scientific article published on 10 September 2020

[Molecular and metabolic changes in human clear cell liver foci].

scientific article

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