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List of works by Radim Havelek

Accumulation of DNA Damage and Cell Death after Fractionated Irradiation

scientific article published on March 25, 2011

Alkaloids from Narcissus poeticus cv. Pink Parasol of various structural types and their biological activity.

scientific article published on 14 December 2017

Anticancer potential of Amaryllidaceae alkaloids evaluated by screening with a panel of human cells, real-time cellular analysis and Ehrlich tumor-bearing mice

scientific article published on 26 July 2017

Bersavine: A Novel Bisbenzylisoquinoline Alkaloidwith Cytotoxic, Antiproliferative and Apoptosis-Inducing Effects on Human Leukemic Cells

scientific article published on 20 February 2020

Boldine Inhibits Mouse Mammary Carcinoma In Vivo and Human MCF-7 Breast Cancer Cells In Vitro.

scientific article published on 9 September 2016

Changes in the response of MCF-7 cells to ionizing radiation after the combination of ATM and DNA-PK inhibition

scientific article

Chemical and Biological Aspects of Montanine-Type Alkaloids Isolated from Plants of the Amaryllidaceae Family

scientific article published on 16 May 2020

Comparative cytotoxicity of chelidonine and homochelidonine, the dimethoxy analogues isolated from Chelidonium majus L. (Papaveraceae), against human leukemic and lung carcinoma cells.

scientific article published on 22 January 2016

Effective Method of Purification of Betulin from Birch Bark: The Importance of Its Purity for Scientific and Medicinal Use

scientific article

Enhanced cytotoxicity of indenyl molybdenum(ii) compounds bearing a thiophene function

scientific article published on 08 July 2019

Gamma radiation induces senescence in human adult mesenchymal stem cells from bone marrow and periodontal ligaments.

scientific article published on 20 March 2012

Haemanthamine alters sodium butyrate-induced histone acetylation, p21WAF1/Cip1 expression, Chk1 and Chk2 activation and leads to increased growth inhibition and death in A2780 ovarian cancer cells.

scientific article

In-vitro and in-vivo evaluation of the anticancer activity of diruthenium-2, a new trithiolato arene ruthenium complex [(η6-p-MeC6H4Pri)2Ru2(μ-S-p-C6H4OH)3]Cl

scientific article published on 16 May 2016

Ionizing radiation increases primary cilia incidence and induces multiciliation in C2C12 myoblasts

scientific article

Irradiation of adult human dental pulp stem cells provokes activation of p53, cell cycle arrest, and senescence but not apoptosis.

scientific article published on 13 September 2010

LC-MS/MS method for the determination of haemanthamine in rat plasma, bile and urine and its application to a pilot pharmacokinetic study.

scientific article published on 17 November 2015

Lymphocyte subsets and their H2AX phosphorylation in response to in vivo irradiation in rats

scientific article published in February 2013

Scoulerine affects microtubule structure, inhibits proliferation, arrests cell cycle and thus culminates in the apoptotic death of cancer cells.

scientific article published on 19 March 2018

Specific inhibition of Wee1 kinase and Rad51 recombinase: a strategy to enhance the sensitivity of leukemic T-cells to ionizing radiation-induced DNA double-strand breaks.

scientific article published on 5 October 2014

Study of antitumor effect of selected vanadium and molybdenum organometallic complexes in human leukemic T-cells.

scientific article published on 18 September 2015

Synthesis, structural characterization, docking, lipophilicity and cytotoxicity of 1-[(1R)-1-(6-fluoro-1,3-benzothiazol-2-yl)ethyl]-3-alkyl carbamates, novel acetylcholinesterase and butyrylcholinesterase pseudo-irreversible inhibitors

scientific article published on 26 February 2016

The cytotoxic effect of α-tomatine in MCF-7 human adenocarcinoma breast cancer cells depends on its interaction with cholesterol in incubation media and does not involve apoptosis induction.

scientific article published on 02 October 2013

The effect of ATM kinase inhibition on the initial response of human dental pulp and periodontal ligament mesenchymal stem cells to ionizing radiation.

scientific article

The effect of Amaryllidaceae alkaloids haemanthamine and haemanthidine on cell cycle progression and apoptosis in p53-negative human leukemic Jurkat cells.

scientific article published on 29 October 2013

The response of human ectomesenchymal dental pulp stem cells to cisplatin treatment.

scientific article