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List of works by Hervé Chneiweiss

30 years before, and tomorrow?

scientific article published on 01 March 2015

A cell-penetrating peptide based on the interaction between c-Src and connexin43 reverses glioma stem cell phenotype.

scientific article

A driver role for GABA metabolism in controlling stem and proliferative cell state through GHB production in glioma

scientific article published on 28 December 2016

A national debate to prepare the 2018 French bioethics law

scientific article published on 16 February 2018

A preclinical mouse model of glioma with an alternative mechanism of telomere maintenance (ALT).

scientific article

ALT cancer cells are specifically sensitive to lysine acetyl transferase inhibition

scientific article published on 22 January 2019

Absence of the Adaptor Protein PEA-15 Is Associated with Altered Pattern of Th Cytokines Production by Activated CD4+ T Lymphocytes In Vitro, and Defective Red Blood Cell Alloimmune Response In Vivo

scientific article published on 28 August 2015

Akt down-regulates ERK1/2 nuclear localization and angiotensin II-induced cell proliferation through PEA-15.

scientific article

Alkaloids from Rutaceae: activities of canthin-6-one alkaloids and synthetic analogues on glioblastoma stems cells

article published in 2012

Alternative lengthening of telomeres in human glioma stem cells.

scientific article published in March 2011

An ANOCEF genomic and transcriptomic microarray study of the response to radiotherapy or to alkylating first-line chemotherapy in glioblastoma patients

scientific article

Analysis of the SCAI CAG repeat in a large number of families with dominant ataxia: Clinical and molecular correlations

article

Antiproliferative activity of trans-avicennol from Zanthoxylum chiloperone var. angustifolium against human cancer stem cells.

scientific article

Astrocytes reverted to a neural progenitor-like state with transforming growth factor alpha are sensitized to cancerous transformation.

scientific article published on October 2009

Autosomal dominant cerebellar ataxia type I in Martinique (French West Indies)

article

Autosomal dominant cerebellar ataxia type I in Martinique (French West Indies): genetic analysis of three unrelated SCA2 families

scientific article published in May 1996

Biogenic amine-sensitive adenylate cyclases in primary culture of neuronal or glial cells from mesencephalon ⬇️

scientific article published on June 8, 1984

Bisacodyl and its cytotoxic activity on human glioblastoma stem-like cells. Implication of inositol 1,4,5-triphosphate receptor dependent calcium signaling.

scientific article

CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors

scientific article

CHD7 promotes proliferation of neural stem cells mediated by MIF.

scientific article published on 13 December 2016

CRISPR-Cas9: A European position on genome editing.

scientific article published in January 2017

Calcium fingerprints induced by calmodulin interactors in eukaryotic cells

scientific article published on 14 December 2008

Calcium signaling orchestrates glioblastoma development: Facts and conjunctures

scientific article published on 27 January 2016

Capture at the single cell level of metabolic modules distinguishing aggressive and indolent glioblastoma cells

scientific article published on 16 October 2019

Cell-based therapy using miR-302-367 expressing cells represses glioblastoma growth

scientific article published on 30 March 2017

Cellular expression, developmental regulation, and phylogenic conservation of PEA-15, the astrocytic major phosphoprotein and protein kinase C substrate.

scientific article published in March 1995

Changes in chromatin state reveal ARNT2 at a node of a tumorigenic transcription factor signature driving glioblastoma cell aggressiveness.

scientific article published on 17 November 2017

Chemical Library Screening and Structure-Function Relationship Studies Identify Bisacodyl as a Potent and Selective Cytotoxic Agent Towards Quiescent Human Glioblastoma Tumor Stem-Like Cells

scientific article

Clinical relevance of tumor cells with stem-like properties in pediatric brain tumors.

scientific article

Commentary: Just Say "No".

scientific article published in October 2017

Comparative expression study of the endo-G protein coupled receptor (GPCR) repertoire in human glioblastoma cancer stem-like cells, U87-MG cells and non malignant cells of neural origin unveils new potential therapeutic targets

scientific article

Connective-Tissue Growth Factor (CTGF/CCN2) Induces Astrogenesis and Fibronectin Expression of Embryonic Neural Cells In Vitro

scientific article published on 4 August 2015

Could Failure in Preimplantation Genetic Diagnosis Justify Editing the Human Embryo Genome?

scientific article published on 2 February 2018

Critical multiple angiogenic factors secreted by glioblastoma stem-like cells underline the need for combinatorial anti-angiogenic therapeutic strategies.

scientific article published on January 2013

Cyclic AMP accumulation induces a rapid desensitization of the cyclic AMP-dependent protein kinase in mouse striatal neurons

scientific article published in November 1991

Cyclic AMP reduces adhesion of isolated neuronal growth cones from developing rat forebrain to an astrocytic cell line from embryonic mouse striatum

scientific article

Cyclic-amp dependent protein kinase in mouse striatal neurones and astrocytes in primary culture: development, subcellular distribution and stimulation of endogenous phosphorylation.

scientific article

DLG1/SAP97 modulates transforming growth factor alpha bioavailability

scientific article published on 27 September 2008

DOCK4 promotes loss of proliferation in glioblastoma progenitor cells through nuclear beta-catenin accumulation and subsequent miR-302-367 cluster expression

scientific article

Data in support of metabolic reprogramming in transformed mouse cortical astrocytes: A proteomic study

scientific article

Death effector domain protein PEA-15 potentiates Ras activation of extracellular signal receptor-activated kinase by an adhesion-independent mechanism

scientific article

Development of a DIPG Orthotopic Model in Mice Using an Implantable Guide-Screw System

scientific article

Differential proteomic analysis of human glioblastoma and neural stem cells reveals HDGF as a novel angiogenic secreted factor.

scientific article

Dopamine-induced homologous and heterologous desensitizations of adenylate cyclase-coupled receptors on striatal neurons

scientific article published in October 1990

ERK-mediated loss of miR-199a-3p and induction of EGR1 act as a "toggle switch" of GBM cell dedifferentiation into NANOG- and OCT4-positive cells

scientific article published on 04 May 2020

Endothelial secreted factors suppress mitogen deprivation-induced autophagy and apoptosis in glioblastoma stem-like cells

scientific article

Endothelin induces a calcium-dependent phosphorylation of PEA-15 in intact astrocytes: identification of Ser104 and Ser116 phosphorylated, respectively, by protein kinase C and calcium/calmodulin kinase II in vitro

scientific article

Expanded polyglutamine peptides disrupt EGF receptor signaling and glutamate transporter expression in Drosophila.

scientific article

Expression of transfected stathmin cDNA reveals novel phosphorylated forms associated with developmental and functional cell regulation ⬇️

scientific article published on October 15, 1992

Flavonoids suppress human glioblastoma cell growth by inhibiting cell metabolism, migration, and by regulating extracellular matrix proteins and metalloproteinases expression.

scientific article published on 22 September 2015

Fostering responsible research with genome editing technologies: a European perspective.

scientific article published on 20 July 2017

Functional analysis of HOXD9 in human gliomas and glioma cancer stem cells

scientific article

GFAPdelta immunostaining improves visualization of normal and pathologic astrocytic heterogeneity.

scientific article

Gender equality in Machado–Joseph disease

article published in 1995

Genome Editing: Promoting Responsible Research

scientific article published on 01 June 2019

Global citizen deliberation on genome editing

scientific article published on 01 September 2020

Glut3 Addiction Is a Druggable Vulnerability for a Molecularly Defined Subpopulation of Glioblastoma

scientific article

HG-51DELTA-24-RDG IN COMBINATION WITH RADIOTHERAPY FOR DIPG: OPENING NEW THERAPEUTIC AVENUES.

scientific article published on 30 May 2016

Intraneuronal delivery of protein kinase C pseudosubstrate leads to growth cone collapse

scientific article published on 01 November 1995

Keeping TNF-induced apoptosis under control in astrocytes: PEA-15 as a 'double key' on caspase-dependent and MAP-kinase-dependent pathways.

scientific article

Knock-out of the neural death effector domain protein PEA-15 demonstrates that its expression protects astrocytes from TNFalpha-induced apoptosis

scientific article (publication date: October 1999)

Les années 2000

Les années 2010

Marked phenotypic heterogeneity associated with expansion of a CAG repeat sequence at the spinocerebellar ataxia 3/Machado-Joseph disease locus

scientific article published on October 1995

Metabolic reprogramming in transformed mouse cortical astrocytes: A proteomic study

scientific article published on 23 October 2014

Médecine/Scienceset les passerelles du temps

NG2+/Olig2+ cells are the major cycle-related cell population of the adult human normal brain

scientific article

New variants of malignant glioneuronal tumors: a clinicopathological study of 40 cases.

scientific article published in December 2004

Opposite effects of GCN5 and PCAF knockdowns on the alternative mechanism of telomere maintenance.

scientific article published on 17 February 2017

PEA-15 mediates cytoplasmic sequestration of ERK MAP kinase

scientific article (publication date: August 2001)

Phenotypic variability in autosomal dominant cerebellar ataxia type I is unrelated to genetic heterogeneity

scientific article published on 01 December 1993

Phosphoprotein enriched in astrocytes-15 kDa expression inhibits astrocyte migration by a protein kinase C delta-dependent mechanism

scientific article

Plasticity of the cellular phenotype

scientific article published on 19 April 2011

Polyneuropathy in autosomal dominant cerebellar ataxias: Phenotype-genotype correlation

scientific article published on 01 June 1999

Proteomic analysis of oligodendrogliomas expressing a mutant isocitrate dehydrogenase-1.

scientific article published on 22 September 2011

Radiosensitization Effect of Talazoparib, a Parp Inhibitor, on Glioblastoma Stem Cells Exposed to Low and High Linear Energy Transfer Radiation.

scientific article published on 26 February 2018

Regulation of expression of phospholipase D1 and D2 by PEA-15, a novel protein that interacts with them

scientific article (publication date: 10 November 2000)

Retinoblastoma protein regulates the crosstalk between autophagy and apoptosis, and favors glioblastoma resistance to etoposide.

scientific article published on 15 August 2013

SCA2 is not a major locus for ADCA type I in French families

article

SIRT2, a multi-talented deacetylase

scientific article

Scientific publication and therapeutic cloning now face Hwang mystification: more than a "Cloningate"

scientific article published in February 2006

Secreted factors from brain endothelial cells maintain glioblastoma stem-like cell expansion through the mTOR pathway.

scientific article published on April 2011

Sirtuin-2 activity is required for glioma stem cell proliferation arrest but not necrosis induced by resveratrol

scientific article

Spinocerebellar ataxia 3 and Machado-Joseph disease: clinical, molecular, and neuropathological features

scientific article published in April 1996

Stathmin is a major phosphoprotein and cyclic AMP-dependent protein kinase substrate in mouse brain neurons but not in astrocytes in culture: regulation during ontogenesis

scientific article published on 01 September 1989

Stathmin phosphorylation is regulated in striatal neurons by vasoactive intestinal peptide and monoamines via multiple intracellular pathways

scientific article published in January 1992

Stathmin phosphorylation patterns discriminate between distinct transduction pathways of human T lymphocyte activation through CD2 triggering

scientific article published on 01 August 1991

The HIF1α/JMY pathway promotes glioblastoma stem-like cell invasiveness after irradiation

scientific article published on 30 October 2020

The PEA-15/PED protein protects glioblastoma cells from glucose deprivation-induced apoptosis via the ERK/MAP kinase pathway.

scientific article published on 13 August 2007

The anti-hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ-dependent inhibition of the AKT pathway

scientific article

The flavonoid rutin and its aglycone quercetin modulate the microglia inflammatory profile improving antiglioma activity

scientific article published on 03 May 2019

The major astrocytic phosphoprotein PEA-15 is encoded by two mRNAs conserved on their full length in mouse and human

scientific article

The miR 302-367 cluster drastically affects self-renewal and infiltration properties of glioma-initiating cells through CXCR4 repression and consequent disruption of the SHH-GLI-NANOG network

scientific article published on July 2011

The multifunctional protein PEA-15 is involved in the control of apoptosis and cell cycle in astrocytes

scientific article

The oncolytic virus Delta-24-RGD elicits an antitumor effect in pediatric glioma and DIPG mouse models

scientific article published on 28 May 2019

The relationship between brain tumor cell invasion of engineered neural tissues and in vivo features of glioblastoma ⬇️

scientific article published on July 27, 2013

The tsunami named CRISPR/Cas9

scientific article published on 17 May 2018

Transforming growth factor alpha acts as a gliatrophin for mouse and human astrocytes.

scientific article published on 13 March 2006

Tumorigenic potential of miR-18A* in glioma initiating cells requires NOTCH-1 signaling.

scientific article

Vasoactive intestinal polypeptide receptors linked to an adenylate cyclase, and their relationship with biogenic amine- and somatostatin-sensitive adenylate cyclases on central neuronal and glial cells in primary cultures

scientific article published on 01 March 1985

WNK1 kinase and its partners Akt, SGK1 and NBC-family Na+/HCO3- cotransporters are potential therapeutic targets for glioblastoma stem-like cells linked to Bisacodyl signaling.

scientific article

[A dimension more and more individualized]

scientific article published on 01 August 2007

[An astrocytic basis of epilepsy]

scientific article published on 01 December 2005

[An ethics of dialogue sciences-society]

scientific article published on 01 June 2015

[Back from Hong Kong or ethics at the time of a genetic increase of the human person]

scientific article published on 01 March 2019

[Biomedical research thought in French: New year, new concepts]

scientific article published on 01 January 2016

[Does the ataxo-choreic form of DRPLA exist in Europe? Search of mutation in 120 families]

scientific article published on 01 November 1995

[Ethics components in communicating science]

scientific article published on 18 February 2019

[Finally French human embryonic stem cells get their launch]

scientific article published on 01 March 2006

[In the genomic great plains country. Episode 1: the double helix market]

scientific article published on 01 April 2003

[Lamarck as a special guest of the 30(th) anniversary of m/s]

scientific article published on 01 August 2014

[Médecine/sciences in the bioeconomy era]

scientific article published on 27 January 2012

[On misery coast. Episode 1: the market of vital drugs].

scientific article

[On the steep mountain trail of bioethics. Episode 1: cloning peaks]

scientific article published on 01 February 2003

[On the steep mountain trail of bioethics. Episode 2: in a vocabulary haze]

scientific article published on 01 March 2003

[On the steep mountain trail of bioethics. Episode 3: into the realm of eugenics]

scientific article published on 01 May 2003

[Our students are talented!]

scientific article published on 01 June 2016

[Since 30 years and tomorrow too: publishing biomedical science in French]

scientific article published on 01 February 2015

[Why a scientific review in French?]

scientific article published on 24 January 2014

médecine/sciences 2013: new goals, new challenges

scientific article published on 25 January 2013

médecine/sciences2011

article published in 2011

p38/SAPK2 controls gap junction closure in astrocytes

scientific article published in May 2004

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