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List of works by José M. Andreu

3-Hydroxyphenylpropionate and phenylpropionate are synergistic activators of the MhpR transcriptional regulator from Escherichia coli

scientific article published on 11 June 2009

A purple acidophilic di-ferric DNA ligase from Ferroplasma

scholarly article

Alterations of rings B and C of colchicine are cumulative in overall binding to tubulin but modify each kinetic step

scientific article published on 01 December 1996

Assembly of archaeal cell division protein FtsZ and a GTPase-inactive mutant into double-stranded filaments.

scientific article

Bacterial cell division proteins as antibiotic targets

scientific article published on 04 April 2014

Bacterial tubulin distinct loop sequences and primitive assembly properties support its origin from a eukaryotic tubulin ancestor

scientific article

Beyond a Fluorescent Probe: Inhibition of Cell Division Protein FtsZ by mant-GTP Elucidated by NMR and Biochemical Approaches.

scientific article published on 17 August 2015

C-terminal cleavage of tubulin by subtilisin enhances ring formation.

scientific article

Centrosome and spindle pole microtubules are main targets of a fluorescent taxoid inducing cell death.

scientific article published on May 2001

Changes in Microtubule Protofilament Number Induced by Taxol Binding to an Easily Accessible Site

scientific article published in Journal of Biological Chemistry

Chrysophaentins are competitive inhibitors of FtsZ and inhibit Z-ring formation in live bacteria

scientific article published on 25 July 2013

Comparative study of the colchicine binding site and the assembly of fish and mammalian microtubule proteins

scientific article published on 01 January 1995

Control of the Structural Stability of the Tubulin Dimer by One High Affinity Bound Magnesium Ion at Nucleotide N-site

scientific article published in Journal of Biological Chemistry

Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.

scientific article published on 7 January 2007

Cyclostreptin derivatives specifically target cellular tubulin and further map the paclitaxel site.

scientific article published on 30 December 2011

Different kinetic pathways of the binding of two biphenyl analogues of colchicine to tubulin

scientific article published on 01 April 1996

Effect of 2'-OH acetylation on the bioactivity and conformation of 7-O-[N-(4'-fluoresceincarbonyl)-L-alanyl]taxol. A NMR-fluorescence microscopy study.

scientific article

Endowing indole-based tubulin inhibitors with an anchor for derivatization: highly potent 3-substituted indolephenstatins and indoleisocombretastatins.

scientific article published on 20 March 2013

Energetics and geometry of FtsZ polymers: nucleated self-assembly of single protofilaments

scientific article

Essential cell division protein FtsZ assembles into one monomer-thick ribbons under conditions resembling the crowded intracellular environment

scientific article

Fast kinetics of Taxol binding to microtubules. Effects of solution variables and microtubule-associated proteins

scientific article

Fluorescent taxoid probes for microtubule research.

scientific article published on January 2010

Folding, stability and polymerization properties of FtsZ chimeras with inserted tubulin loops involved in the interaction with the cytosolic chaperonin CCT and in microtubule formation

scientific article published on 18 December 2004

FtsZ filament structures in different nucleotide states reveal the mechanism of assembly dynamics

scientific article published on 21 March 2022

Hydrodynamic analysis of tubulin dimer and double rings

scientific article published on 01 April 1994

Insights into nucleotide recognition by cell division protein FtsZ from a mant-GTP competition assay and molecular dynamics.

scientific article

Insights into the Interaction of Discodermolide and Docetaxel with Tubulin. Mapping the Binding Sites of Microtubule-Stabilizing Agents by Using an Integrated NMR and Computational Approach ⬇️

scientific article published on May 13, 2011

Interactions of bacterial cell division protein FtsZ with C8-substituted guanine nucleotide inhibitors. A combined NMR, biochemical and molecular modeling perspective.

scientific article published on 24 October 2013

Inter‐conversion of catalytic abilities in a bifunctional carboxyl/feruloyl‐esterase from earthworm gut metagenome ⬇️

scientific article published on July 17, 2009

Macromolecular accessibility of fluorescent taxoids bound at a paclitaxel binding site in the microtubule surface.

scientific article published on 18 November 2004

Magnesium-induced linear self-association of the FtsZ bacterial cell division protein monomer. The primary steps for FtsZ assembly

scientific article published on 01 April 2000

Mapping Surface Sequences of the Tubulin Dimer and Taxol-Induced Microtubules with Limited Proteolysis†

scientific article published on 01 November 1996

Membrane adenosine triphosphatase of Micrococcus lysodeikticus. Isolation of two forms of the enzyme complex and correlation between enzymatic stability, latency and activity

scientific article published on February 16, 1976

Microtubule interactions with chemically diverse stabilizing agents: thermodynamics of binding to the paclitaxel site predicts cytotoxicity

scientific article published in December 2005

Modulation of Microtubule Interprotofilament Interactions by Modified Taxanes ⬇️

scientific article published on December 20, 2011

Molecular Recognition of Epothilones by Microtubules and Tubulin Dimers Revealed by Biochemical and NMR Approaches

scientific article published on 25 February 2014

Molecular recognition of taxol by microtubules. Kinetics and thermodynamics of binding of fluorescent taxol derivatives to an exposed site

scientific article published on 01 August 2000

NMR determination of the bioactive conformation of peloruside A bound to microtubules.

scientific article

New interfacial microtubule inhibitors of marine origin, PM050489/PM060184, with potent antitumor activity and a distinct mechanism.

scientific article

Non-cytotoxic variants of the Kid protein that retain their auto-regulatory activity

scientific article published in September 2003

Novel polyphenol oxidase mined from a metagenome expression library of bovine rumen: biochemical properties, structural analysis, and phylogenetic relationships.

scientific article

Nucleotide-induced folding of cell division protein FtsZ from Staphylococcus aureus

scientific article published on 29 January 2020

Optimization of taxane binding to microtubules: binding affinity dissection and incremental construction of a high-affinity analog of paclitaxel.

scientific article

PM060184, a new tubulin binding agent with potent antitumor activity including P-glycoprotein over-expressing tumors

scientific article

Phage phi29 protein p6 is in a monomer-dimer equilibrium that shifts to higher association states at the millimolar concentrations found in vivo

scientific article published on 01 September 1997

Polymerization of nucleotide-free, GDP- and GTP-bound cell division protein FtsZ: GDP makes the difference

scientific article

Possible binding site for paclitaxel at microtubule pores.

scientific article

Probing FtsZ and tubulin with C8-substituted GTP analogs reveals differences in their nucleotide binding sites

scientific article

Probing the pore drug binding site of microtubules with fluorescent taxanes: evidence of two binding poses

scientific article published in March 2010

Purification and assembly of bacterial tubulin BtubA/B and constructs bearing eukaryotic tubulin sequences.

scientific article published in January 2013

Reversible unfolding of FtsZ cell division proteins from archaea and bacteria. Comparison with eukaryotic tubulin folding and assembly

scientific article

Role of the colchicine ring A and its methoxy groups in the binding to tubulin and microtubule inhibition

scientific article published in June 1998

Self assembly of human septin 2 into amyloid filaments

scientific article published on 28 September 2011

Septin C-terminal domain interactions: implications for filament stability and assembly

scientific article published in March 2012

Solution structure of GDP-tubulin double rings to 3 nm resolution and comparison with microtubules

scientific article published on 01 April 1994

Stability of Escherichia coli phosphoenolpyruvate carboxykinase against urea-induced unfolding and ligand effects

scientific article

Stathmin and Interfacial Microtubule Inhibitors Recognize a Naturally Curved Conformation of Tubulin Dimers

scientific article

Stoichiometric and substoichiometric inhibition of tubulin self-assembly by colchicine analogues

scientific article published on 01 March 1996

Structural stability of the PsbQ protein of higher plant photosystem II.

scientific article published on November 2004

Substructure of F1-ATPase (BF1 factor) from Micrococcus lysodeikticus. A cross-linking study with diimido esters

scientific article published on 01 December 1980

Synthesis and antimitotic and tubulin interaction profiles of novel pinacol derivatives of podophyllotoxins.

scientific article published on 23 July 2012

Synthetic developmental regulator MciZ targets FtsZ across Bacillus species and inhibits bacterial division

scientific article published on 17 February 2019

Synthetic inhibitors of bacterial cell division targeting the GTP-binding site of FtsZ.

scientific article

Targeting the assembly of bacterial cell division protein FtsZ with small molecules

scientific article

Tau induces ring and microtubule formation from alphabeta-tubulin dimers under nonassembly conditions

scientific article published on 01 August 2004

Taxanes: microtubule and centrosome targets, and cell cycle dependent mechanisms of action

scientific article (publication date: June 2003)

The Interaction of Microtubules with Stabilizers Characterized at Biochemical and Structural Levels ⬇️

scientific article published on 01 January 2009

The active GTP- and ground GDP-liganded states of tubulin are distinguished by the binding of chiral isomers of ethyl 5-amino-2-methyl-1,2-dihydro-3-phenylpyrido[3,4-b]pyrazin-7-yl carbamate

scientific article published on 01 January 1998

The antibacterial cell division inhibitor PC190723 is an FtsZ polymer-stabilizing agent that induces filament assembly and condensation.

scientific article published on 8 March 2010

The interaction of baccatin III with the taxol binding site of microtubules determined by a homogeneous assay with fluorescent taxoid

scientific article

The interactions of cell division protein FtsZ with guanine nucleotides.

scientific article published on 31 October 2007

The measurement of cooperative protein self-assembly by turbidity and other techniques

scientific article published on 01 January 1986

The microtubule stabilizing agent laulimalide does not bind in the taxoid site, kills cells resistant to paclitaxel and epothilones, and may not require its epoxide moiety for activity.

scientific article

The nucleotide switch of tubulin and microtubule assembly: a polymerization-driven structural change

scientific article published on 01 May 2006

The structural assembly switch of cell division protein FtsZ probed with fluorescent allosteric inhibitors.

scientific article published on 21 October 2016

Thermal transitions in the structure of tubulin. Environments of aromatic aminoacids

scientific article published on 01 January 1991

Tubulin Secondary Structure Analysis, Limited Proteolysis Sites, and Homology to FtsZ†

article

Tubulin homolog TubZ in a phage-encoded partition system

scientific article

Urea-induced unfolding studies of free- and ligand-bound tetrameric ATP-dependent Saccharomyces cerevisiae phosphoenolpyruvate carboxykinase. Influence of quaternary structure on protein conformational stability

scientific article

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