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List of works by Giuseppe Castello

A holistic approach to study the effects of natural antioxidants on inflammation and liver cancer

scientific article published on January 2014

A possible predictive marker of progression for hepatocellular carcinoma

scientific article

Adjuvant treatment of malignant melanoma: where are we?

scientific article

Assessment of genetic instability in melanocytic skin lesions through microsatellite analysis of benign naevi, dysplastic naevi, and primary melanomas and their metastases

scientific article published in April 2003

Bone marrow cell transcripts from Fanconi anaemia patients reveal in vivo alterations in mitochondrial, redox and DNA repair pathways.

scientific article

CD4(+)CD45RA(+)CXCR4 (+) lymphocytes are inversely associated with progression in stages I-III melanoma patients.

scientific article published on 25 September 2009

CXC chemokine receptor 4 is expressed in uveal malignant melanoma and correlates with the epithelioid-mixed cell type

scientific article published on 05 April 2007

Cancer biomarker profiling in patients with chronic hepatitis C virus, liver cirrhosis and hepatocellular carcinoma

scientific article published on 3 April 2013

Common structural interactions between the receptors CXCR3, CXCR4 and CXCR7 complexed with their natural ligands, CXCL11 and CXCL12, by a modeling approach

scientific article published on 15 June 2013

CytReD: A database collecting human cytokinome information.

scientific article published on 26 May 2011

Cytokinome profile of patients with type 2 diabetes and/or chronic hepatitis C infection

scientific article

Dissimilar cytokine patterns in different human liver and colon cancer cell lines

scientific article published on 21 September 2013

Early diagnosis of malignant melanoma: Proposal of a working formulation for the management of cutaneous pigmented lesions from the Melanoma Cooperative Group.

scientific article published in June 2003

Effects of Lipoic Acid, Caffeic Acid and a Synthesized Lipoyl-Caffeic Conjugate on Human Hepatoma Cell Lines

scientific article published on 27 July 2011

Evaluation of selenite effects on selenoproteins and cytokinome in human hepatoma cell lines.

scientific article published on 26 February 2013

Evidence of publication bias in clinical trials of biotherapies for solid tumors

scientific article published on 01 February 2005

Expression of CXCR4 Predicts Poor Prognosis in Patients with Malignant Melanoma

scientific article published on 01 March 2005

Factors predicting the occurrence of germline mutations in candidate genes among patients with cutaneous malignant melanoma from South Italy

scientific article published on 19 October 2006

Fc gamma receptor IIIa polymorphisms in advanced colorectal cancer patients correlated with response to anti-EGFR antibodies and clinical outcome.

scientific article published on 21 November 2012

HCV-related hepatocellular carcinoma: From chronic inflammation to cancer

scientific article

Human Cytokinome: a new challenge for systems biology.

scientific article published on 6 October 2010

Human immunodeficiency virus per se exerts atherogenic effects.

scientific article published in November 2008

Immune signatures in human PBMCs of idiotypic vaccine for HCV-related lymphoproliferative disorders

scientific article (publication date: 19 February 2010)

Impaired diastolic function in naïve untreated human immunodeficiency virus infected patients.

scientific article

In vivo prooxidant state in Werner syndrome (WS): results from three WS patients and two WS heterozygotes

scientific article published in May 2005

Inhibitory effects of anti-CXCR4 antibodies on human colon cancer cells

scientific article published on 11 December 2004

Lauroside B, a megastigmane glycoside from Laurus nobilis (bay laurel) leaves, induces apoptosis in human melanoma cell lines by inhibiting NF-κB activation

scientific article

Mitochondrial dysfunction in some oxidative stress-related genetic diseases: Ataxia-Telangiectasia, Down Syndrome, Fanconi Anaemia and Werner Syndrome

scientific article published on 18 March 2010

Multiple evidence for an early age pro-oxidant state in Down Syndrome patients

scientific article published on 13 April 2006

Mutation analysis of candidate genes in melanoma-prone families

article

Overexpression of both CXC chemokine receptor 4 and vascular endothelial growth factor proteins predicts early distant relapse in stage II-III colorectal cancer patients

scientific article published on May 2006

Oxidative stress and mitochondrial dysfunction across broad-ranging pathologies: toward mitochondria-targeted clinical strategies

scientific article

Oxidative stress and mitochondrial dysfunction in Down syndrome.

scientific article published on January 2012

Oxidative stress in Fanconi anaemia: from cells and molecules towards prospects in clinical management ⬇️

scientific article published on January 1, 2012

Pegylated arginine deiminase treatment of patients with metastatic melanoma: results from phase I and II studies

scientific article published in October 2005

Pegylated arginine deiminase treatment of patients with unresectable hepatocellular carcinoma: results from phase I/II studies

scientific article

Peptides targeting chemokine receptor CXCR4: structural behavior and biological binding studies

scientific article published on 28 January 2014

Phase II study of pegylated arginine deiminase for nonresectable and metastatic hepatocellular carcinoma

scientific article published on 29 March 2010

Preclinical development of a novel class of CXCR4 antagonist impairing solid tumors growth and metastases

scientific article

Prognostic value of serum VEGF in melanoma patients: a pilot study

scientific article published on 01 November 2004

Regulatory T cell frequency in patients with melanoma with different disease stage and course, and modulating effects of high-dose interferon-alpha 2b treatment

scientific article

Regulatory T cells, interleukin (IL)-6, IL-8, vascular endothelial growth factor (VEGF), CXCL10, CXCL11, epidermal growth factor (EGF) and hepatocyte growth factor (HGF) as surrogate markers of host immunity in patients with renal cell carcinoma

scientific article published on 15 March 2013

Serial detection of circulating tumour cells by reverse transcriptase-polymerase chain reaction assays is a marker for poor outcome in patients with malignant melanoma

scientific article

Serum cytokine levels as putative prognostic markers in the progression of chronic HCV hepatitis to cirrhosis

scientific article published on 17 November 2010

Serum cytokine levels in patients with hepatocellular carcinoma

scientific article

Soluble interleukin-2 receptor in stage I–III melanoma

scientific article published on 01 February 2006

Structural and functional studies of the human selenium binding protein-1 and its involvement in hepatocellular carcinoma

scientific article published on 19 February 2011

Structure-function relationship and evolutionary history of the human selenoprotein M (SelM) found over-expressed in hepatocellular carcinoma

scientific article published on 9 December 2013

Targeting the inflammation in HCV-associated hepatocellular carcinoma: a role in the prevention and treatment ⬇️

scientific article published on November 3, 2010

The N-terminal region of CXCL11 as structural template for CXCR3 molecular recognition: synthesis, conformational analysis, and binding studies

scientific article published on 23 May 2012

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