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List of works by Colin Longstaff

A collaborative study to establish the 3rd International Standard for tissue plasminogen activator.

scientific article published in August 2002

A proposed reference method for plasminogen activators that enables calculation of enzyme activities in SI units

scientific article published in August 2004

A reunification of the US ("NIH") and International Unit into a single standard for Thrombin

scientific article published in February 2005

Activity Regulation by Fibrinogen and Fibrin of Streptokinase from Streptococcus Pyogenes.

scientific article

Ambivalent roles of carboxypeptidase B in the lytic susceptibility of fibrin.

scientific article

An International Collaborative Study to establish the World Health Organization 4th International Standard for Plasmin (13/206): communication from the SSC of the ISTH.

scientific article published on 29 December 2015

An activated-platelet-sensitive nanocarrier enables targeted delivery of tissue plasminogen activator for effective thrombolytic therapy

scientific article published on 23 February 2019

An international collaborative study to calibrate the WHO 2nd International Standard for Ancrod (15/106) and the WHO Reference Reagent for Batroxobin (15/140): communication from the SSC of the ISTH

scientific article published on 01 April 2018

An international collaborative study to establish the WHO 1st international standard for alpha-1-antitrypsin.

scientific article published on 22 December 2010

An international collaborative study to establish the WHO 1st international standards for C1-inhibitor, plasma and concentrate

scientific article published in October 2011

An international collaborative study to establish the WHO 4th International Standard for Streptokinase: communication from the SSC of the ISTH

scientific article published on 29 February 2020

An international collaborative study to investigate a proposed reference method for the determination of potency measurements of fibrinolytics in absolute units

scientific article published on 01 February 2007

An international collaborative study to replace the 1st international standard for prekallikrein activator

scientific article published on 01 February 2005

Applying the science of measurement to biology: Why bother?

scientific article published on 20 June 2019

Basic mechanisms and regulation of fibrinolysis

scientific article published on June 2015

Biorelevant polyanions stabilize fibrin against mechanical and proteolytic decomposition: Effects of polymer size and electric charge

scientific article published on 28 September 2019

Bleeding related to disturbed fibrinolysis

scientific article

Calibration of the WHO 1st international standard and SSC/ISTH secondary coagulation standard for tissue plasminogen activator antigen in plasma

scientific article published on 7 June 2010

Chemical modification of rhodopsin and its effect on regeneration and G protein activation

scientific article published on 01 October 1986

Commentary: biological standardisation in haemostasis and haematology

scientific article published on 26 March 2010

Computational simulations of thrombolysis in acute stroke: Effect of clot size and location on recanalisation

scientific article published on 08 August 2019

DC-SIGN increases the affinity of HIV-1 envelope glycoprotein interaction with CD4.

scientific article

DNA, histones and neutrophil extracellular traps exert anti-fibrinolytic effects in a plasma environment.

scientific article published on 19 March 2015

Deprotonation of the Schiff base of bacteriorhodopsin is obligate in light-induced proton pumping

scientific article published in September 1987

Deprotonation of the Schiff base of rhodopsin is obligate in the activation of the G protein.

scientific article published on June 1986

Development of Shiny app tools to simplify and standardize the analysis of hemostasis assay data: communication from the SSC of the ISTH.

scientific article

Development of an updated assay for prekallikrein activator in albumin and immunoglobulin therapeutics

scientific article published on 28 September 2020

Differences between neonates and adults in carbohydrate sequences and reaction kinetics of plasmin and alpha(2)-antiplasmin

scientific article

Differences between neonates and adults in tissue-type-plasminogen activator (t-PA)-catalyzed plasminogen activation with various effectors and in carbohydrate sequences of fibrinogen chains

scientific article published on 01 August 2001

Extracellular Histones Inhibit Fibrinolysis through Noncovalent and Covalent Interactions with Fibrin

scientific article published on 01 November 2020

Fibrinogen protects neutrophils from the cytotoxic effects of histones and delays neutrophil extracellular trap formation induced by ionomycin

scientific article published on 16 July 2020

Fibrinolysis at the fluid-solid interface of thrombi.

scientific article

Fibrinolysis in a lipid environment: modulation through release of free fatty acids.

scientific article

Fourier transform infrared studies of active-site-methylated rhodopsin. Implications for chromophore-protein interaction, transducin activation, and the reaction pathway.

scientific article

Fractal kinetic behavior of plasmin on the surface of fibrin meshwork.

scientific article

Fragmentation of therapeutic human immunoglobulin preparations

scientific article published on 01 January 1995

Harmonisation of D-dimer - A call for action

scientific article published on 22 November 2015

Hindered dissolution of fibrin formed under mechanical stress

scientific article

How do we assure the quality of biological medicines?

scientific article

How treatment delay may lead to loss of effectiveness of tranexamic acid

scientific article published on 01 April 2020

Increased urokinase and consumption of α -antiplasmin as an explanation for the loss of benefit of tranexamic acid after treatment delay

scientific article published on 13 December 2018

Inhibition of cell surface mediated plasminogen activation by a monoclonal antibody against alpha-Enolase

scientific journal article

Interactions of the type III secretion pathway proteins LcrV and LcrG from Yersinia pestis are mediated by coiled-coil domains.

scientific article published on 9 July 2002

International collaborative study to establish the 3rd International Standard for Streptokinase

scientific article published in August 2004

Kallikrein directly interacts with and activates Factor IX, resulting in thrombin generation and fibrin formation independent of Factor XI

scientific article published on 01 January 2021

Kinetic regulation of the binding of prothrombin to phospholipid membranes

scientific article published on 28 June 2013

Kinetics of the inhibition of fusarium serine proteinases by barley (Hordeum vulgare L.) inhibitors

scientific article published on 07 March 2007

Lytic and mechanical stability of clots composed of fibrin and blood vessel wall components

scientific article published on March 2013

Lytic resistance of fibrin containing red blood cells.

scientific article

Mathematical Modelling of Intravenous Thrombolysis in Acute Ischaemic stroke: Effects of Dose Regimens on Levels of Fibrinolytic Proteins and Clot Lysis Time

scientific article published on 07 March 2019

Measuring fibrinolysis: from research to routine diagnostic assays

scientific article

Mechanical stability and fibrinolytic resistance of clots containing fibrin, DNA, and histones.

scientific article published on 4 January 2013

Mechanism of plasmin generation by S100A10.

scientific article published on 6 April 2017

Methylation of the active-site lysine of rhodopsin

scientific article published on 01 December 1985

Neutralisation of the anti-coagulant effects of heparin by histones in blood plasma and purified systems.

scientific article published on 3 December 2015

Phospholipid barrier to fibrinolysis: role for the anionic polar head charge and the gel phase crystalline structure

scientific article published on 14 July 2004

Photochemistry of monomethylated and permethylated bacteriorhodopsin.

scientific article

Plasminogen activation on the cell surface

scientific article

Recombinant chymotrypsin inhibitor 2: expression, kinetic analysis of inhibition with alpha-chymotrypsin and wild-type and mutant subtilisin BPN', and protein engineering to investigate inhibitory specificity and mechanism

scientific article

Regulation of fibrinolysis by C-terminal lysines operates through plasminogen and plasmin but not tissue-type plasminogen activator

scientific article published on 01 November 2012

Regulatory frameworks in developing countries

scientific article published on 01 April 2005

Release of proteolytic activity following reduction in therapeutic human serum albumin containing products: detection with a new neoepitope endopeptidase immunoassay.

scientific article published on 19 August 2010

Selective Stabilization and Destabilization of Protein Domains in Tissue-Type Plasminogen Activator Using Formulation Excipients

scientific article published on 09 January 2019

Serpin-serine protease binding kinetics: alpha 2-antiplasmin as a model inhibitor

scientific article published on 01 January 1991

The interplay between tissue plasminogen activator domains and fibrin structures in the regulation of fibrinolysis: kinetic and microscopic studies.

scientific article

The need for accurate D-dimer reporting in COVID-19: Communication from the ISTH SSC on fibrinolysis

scientific article published on 01 September 2020

The poor quality of streptokinase products in use in developing countries

scientific article published on 01 May 2005

The regulation by fibrinogen and fibrin of tissue plasminogen activator kinetics and inhibition by plasminogen activator inhibitor 1.

scientific article published in April 2007

Understanding the enzymology of fibrinolysis and improving thrombolytic therapy.

scientific article

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