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List of works by Leanne Stokes

<b>Insights into the structure-activity relationship of glycosides as positive allosteric modulators acting on P2X7 receptors</b>

scientific article published on 17 December 2020

A loss-of-function polymorphism in the human P2X4 receptor is associated with increased pulse pressure.

scientific article

A non-voltage-gated calcium channel with L-type characteristics activated by B cell receptor ligation

scientific article published in November 2003

Association of a P2RX7 gene missense variant with brachycephalic dog breeds

scientific article published on 27 November 2019

CAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulation

scientific article published on 21 June 2013

Characterization of a selective and potent antagonist of human P2X(7) receptors, AZ11645373.

scientific article published on 9 October 2006

Correlation between thyroidal and peripheral blood total T cells, CD8 T cells, and CD8 T- regulatory cells and T-cell reactivity to calsequestrin and collagen XIII in patients with Graves' ophthalmopathy

scientific article published on 22 May 2018

Development of High-Throughput Fluorescent-Based Screens to Accelerate Discovery of P2X Inhibitors from Animal Venoms

scientific article published on 18 September 2019

Dynamic regulation of the P2X4 receptor in alveolar macrophages by phagocytosis and classical activation.

scientific article published on April 2009

Editorial: Roles of Ion Channels in Immune Cells.

scientific article published on 15 February 2016

Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome.

scientific article published on 02 June 2013

Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation.

scientific article

Functional significance of P2RX7 polymorphisms associated with affective mood disorders

scientific article published on 11 May 2010

Genetics of the P2X7 receptor and human disease.

scientific article published on 25 March 2009

Ginsenosides Act As Positive Modulators of P2X4 Receptors

scientific article published on 13 December 2018

Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor.

scientific article published in December 2007

Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist.

scientific article published on 20 November 2007

Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7

scientific article published on 01 March 2019

Neonatal overfeeding alters hypothalamic microglial profiles and central responses to immune challenge long-term

scientific article published on 27 June 2014

Neonatal overfeeding by small-litter rearing sensitises hippocampal microglial responses to immune challenge: Reversal with neonatal repeated injections of saline or minocycline.

scientific article published on 6 October 2017

Non-voltage-gated L-type Ca2+ channels in human T cells: pharmacology and molecular characterization of the major alpha pore-forming and auxiliary beta-subunits.

scientific article

Nucleotides regulate secretion of the inflammatory chemokine CCL2 from human macrophages and monocytes.

scientific article published on 7 September 2014

P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells

scientific article

P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.

scientific article

Paroxetine suppresses recombinant human P2X7 responses

scientific article

Pharmacological Evaluation of Novel Bioisosteres of an Adamantanyl Benzamide P2X7 Receptor Antagonist.

scientific article

Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women

scientific article

Positive allosteric modulation of P2X7 promotes apoptotic cell death over lytic cell death responses in macrophages

scientific article published on 25 November 2019

Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism.

scientific article

Probenecid directly impairs activation of the canine P2X7 receptor

scientific article published on 4 December 2017

Purinergic P2Y2 receptors induce increased MCP-1/CCL2 synthesis and release from rat alveolar and peritoneal macrophages

scientific journal article

R270C polymorphism leads to loss of function of the canine P2X7 receptor.

scientific article published on 13 May 2014

Rab5 regulates internalisation of P2X4 receptors and potentiation by ivermectin ⬇️

scientific article published on October 21, 2012

Rac1 plays a role in CXCL12 but not CCL3-induced chemotaxis and Rac1 GEF inhibitor NSC23766 has off target effects on CXCR4.

scientific article

Recording P2X Receptors Using Whole-Cell Patch Clamp from Native Monocytes and Macrophages

scientific article published on 01 January 2020

Selected ginsenosides of the protopanaxdiol series are novel positive allosteric modulators of P2X7 receptors.

scientific article

Significance of P2X7 Receptor Variants to Human Health and Disease ⬇️

scientific article published on April 1, 2011

Single-nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures

scientific article

Store-Operated Ca(2+) Entry (SOCE) and Purinergic Receptor-Mediated Ca(2+) Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation

scientific article

The P2X7 receptor channel: recent developments and the use of P2X7 antagonists in models of disease

scientific article

The human P2X7 receptor and its role in innate immunity ⬇️

scientific article published on November 1, 2011

Two haplotypes of the P2X(7) receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1beta secretion

scientific article published in April 2010

Understanding the role of P2X7 in affective disorders-are glial cells the major players? ⬇️

scientific article (publication date: 2015)

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