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List of works by Jean-François Ghersi-Egea

A new aspect of the protective functions of the blood-brain barrier: activities of four drug-metabolizing enzymes in isolated rat brain microvessels

scientific article

A simple method for evaluation of superoxide radical production in neural cells under various culture conditions: application to hypoxia.

scientific article published on January 1995

Active transport at the blood-CSF barrier contributes to manganese influx into the brain

scientific article published on 31 March 2011

Are blood-brain interfaces efficient in protecting the brain from reactive molecules?

scientific article

Barriers to Drug Distribution into the Perinatal and Postnatal Brain

scientific article published on 7 March 2018

Blood-brain barrier dysfunction in disorders of the developing brain

scientific article

Blood-brain interfaces: relevance to cerebral drug metabolism.

scientific article published on December 1995

Brain barrier systems: a new frontier in metal neurotoxicological research

scientific article published on October 2003

Brain leukocyte infiltration initiated by peripheral inflammation or experimental autoimmune encephalomyelitis occurs through pathways connected to the CSF-filled compartments of the forebrain and midbrain.

scientific article

Brain mitochondrial cytochrome P-450scc: Spectral and catalytic properties

scientific article published on 01 May 1987

Brain protection at the blood-cerebrospinal fluid interface involves a glutathione-dependent metabolic barrier mechanism

scientific article published on 4 January 2006

Capacity of rat brain to metabolize m-dinitrobenzene: an in vitro study

scientific article published on 01 January 1997

Changes in the cerebrospinal fluid circulatory system of the developing rat: quantitative volumetric analysis and effect on blood-CSF permeability interpretation.

scientific article

Changes of cerebral gamma glutamyltransferase activities after treatment with exogenous inducers

scientific article published on 01 April 1987

Choroid plexus controls brain availability of anti-HIV nucleoside analogs via pharmacologically inhibitable organic anion transporters

scientific article

Choroid plexus glutathione peroxidases are instrumental in protecting the brain fluid environment from hydroperoxides during postnatal development

scientific article published on 27 June 2018

Cimetidine inhibits cerebral and hepatic mitochondrial respiration in rat.

scientific article

Clinical Imaging of Choroid Plexus in Health and in Brain Disorders: A Mini-Review

article

Complexity and developmental changes in the expression pattern of claudins at the blood-CSF barrier.

scientific article

Demonstration of a coupled metabolism-efflux process at the choroid plexus as a mechanism of brain protection toward xenobiotics

scientific article published in August 1999

Detoxification systems, passive and specific transport for drugs at the blood-CSF barrier in normal and pathological situations.

scientific article published in October 2004

Developmental differences in the expression of ABC transporters at rat brain barrier interfaces following chronic exposure to diallyl sulfide

scientific article published on 12 April 2019

Differential expression of the multidrug resistance-related proteins ABCb1 and ABCc1 between blood-brain interfaces

scientific article published in October 2008

Drug metabolism in in vitro organotypic and cellular models of mammalian central nervous system: activities of membrane-bound epoxide hydrolase and NADPH-cytochrome P-450 (c) reductase.

scientific article published in June 1998

Drug metabolizing enzymes in the brain and cerebral microvessels

scientific article published on 01 January 1991

Drug metabolizing enzymes in the rat pituitary gland

scientific article published on January 1, 1992

Efflux transporters in blood-brain interfaces of the developing brain

scientific article

Electronic spin resonance detection of superoxide and hydroxyl radicals during the reductive metabolism of drugs by rat brain preparations and isolated cerebral microvessels

scientific article published in May 1998

Enzyme mediated superoxide radical formation initiated by exogenous molecules in rat brain preparations

scientific article published in August 1991

Ethoxyresorufin O-deethylase activity in rat brain subcellular fractions

scientific article

Fate of cerebrospinal fluid-borne amyloid beta-peptide: rapid clearance into blood and appreciable accumulation by cerebral arteries

scientific article published in August 1996

Glutathione Conjugation at the Blood-CSF Barrier Efficiently Prevents Exposure of the Developing Brain Fluid Environment to Blood-Borne Reactive Electrophilic Substances

scientific article published on 5 March 2018

Histopathologic and ultrastructural features and claudin expression in papillary tumors of the pineal region: a multicenter analysis

scientific article published on 01 June 2012

Impairment of blood-cerebrospinal fluid barrier properties by retrovirus-activated T lymphocytes: reduction in cerebrospinal fluid-to-blood efflux of prostaglandin E2.

scientific article published on 18 July 2005

In vitro evidence that beta-amyloid peptide 1-40 diffuses across the blood-brain barrier and affects its permeability.

scientific article published in January 2000

In vivo study of the elimination from rat brain of an intracerebrally formed xenobiotic metabolite, 1-naphthyl-beta-D-glucuronide

scientific article published in April 1991

Inducibility of rat brain drug-metabolizing enzymes

scientific article published in October 1987

Induction and immunological characterization of the uridine diphosphate-glucuronosyltransferase conjugating 1-naphthol in the rat choroid plexus.

scientific article published in July 1994

Influx mechanisms in the embryonic and adult rat choroid plexus: a transcriptome study

scientific article published on 28 April 2015

Localization of drug-metabolizing enzyme activities to blood-brain interfaces and circumventricular organs.

scientific article

Mechanisms that determine the internal environment of the developing brain: a transcriptomic, functional and ultrastructural approach.

scientific article published on 02 July 2013

Metabolism: a bottleneck in in vitro toxicological test development. The report and recommendations of ECVAM workshop 54

scientific article published on 01 February 2006

Modulation of Mrp1 (ABCc1) and Pgp (ABCb1) by bilirubin at the blood-CSF and blood-brain barriers in the Gunn rat.

scientific article

Molecular anatomy and functions of the choroidal blood-cerebrospinal fluid barrier in health and disease

scientific article

Molecular characterization of circumventricular organs and third ventricle ependyma in the rat: potential markers for periventricular tumors.

scientific article

N-acetylcysteine inhibits bacterial lipopeptide-mediated neutrophil transmigration through the choroid plexus in the developing brain

scientific article published on 23 January 2020

NADPH:cytochrome P-450(c) reductase: biochemical characterization in rat brain and cultured neurons and evolution of activity during development

scientific article published in September 1989

Nicotine raises the influx of permeable solutes across the rat blood-brain barrier with little or no capillary recruitment

scientific article published on 01 July 1995

Novel routes to either racemic or enantiopure α-amino-(4-hydroxy-pyrrolidin-3-yl)acetic acid derivatives and biological evaluation of a new promising pharmacological scaffold

scientific article

P-glycoprotein (ABCB1) and breast cancer resistance protein (ABCG2) localize in the microvessels forming the blood-tumor barrier in ependymomas

scientific article published on 11 March 2010

Posttraumatic invasion of monocytes across the blood-cerebrospinal fluid barrier

scientific article published on 10 August 2011

Potential Pathways for CNS Drug Delivery Across the Blood-Cerebrospinal Fluid Barrier

scientific article

Pro-inflammatory cytokines modulate matrix metalloproteinase secretion and organic anion transport at the blood-cerebrospinal fluid barrier

scientific article

Prostaglandin E2 metabolism in rat brain: Role of the blood-brain interfaces

scientific article published on 4 March 2008

Quantitative measurement of cerebral cytochrome P-450 by second derivative spectrophotometry

scientific article published on 01 July 1987

Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat.

scientific article published in December 1996

Rat choroid plexuses contain myeloid progenitors capable of differentiation toward macrophage or dendritic cell phenotypes

scientific article published in August 2006

Regional brain variations of cytochrome oxidase activity and motor coordination in Lurcher mutant mice

scientific article

Rôles biologiques des éléments traces dans le cerveau – exemples du Zn et du Fe

scientific article published on 05 November 2010

Subcellular distribution of cytochrome P-450 in the brain

scientific article published in June 1986

Subcellular localization of cytochrome P450, and activities of several enzymes responsible for drug metabolism in the human brain

scientific article published in February 1993

Symposium overview: the role of glutathione in neuroprotection and neurotoxicity

scientific article published in October 1999

T-Lymphocytes Traffic into the Brain across the Blood-CSF Barrier: Evidence Using a Reconstituted Choroid Plexus Epithelium

scientific article

The activity of 1-naphthol-UDP-glucuronosyltransferase in the brain

scientific article

The quest for a better insight into physiology of fluids and barriers of the brain: the exemplary career of Joseph D. Fenstermacher.

scientific article

The rapid flow of cerebrospinal fluid from ventricles to cisterns via subarachnoid velae in the normal rat

scientific article published on 01 January 1997

The role of the choroid plexus in neutrophil invasion after traumatic brain injury.

scientific article published on 27 May 2009

Toxic shock syndrome toxin-1 challenges the neuroprotective functions of the choroidal epithelium and induces neurotoxicity.

scientific article published on 30 June 2006

Transport and metabolism at blood-brain interfaces and in neural cells: relevance to bilirubin-induced encephalopathy.

scientific article

Uridine diphosphate-glucuronosyltransferase activities in rat brain microsomes

scientific article published on 01 October 1993

[The choroid plexuses: a dynamic interface between the blood and the cerebrospinal fluid]

scientific article published on 01 June 2005

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