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List of works by Colin Dunstan

A chimeric form of osteoprotegerin inhibits hypercalcemia and bone resorption induced by IL-1beta, TNF-alpha, PTH, PTHrP, and 1, 25(OH)2D3.

scientific article published on September 1999

A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastases

scientific article

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women

scientific article published in March 2004

A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal women. 2004.

scientific article published in December 2005

A toxicity profile of osteoprotegerin in the cynomolgus monkey

scientific article

Accelerated bone resorption, due to dietary calcium deficiency, promotes breast cancer tumor growth in bone.

scientific article published in October 2007

Activation and promotion of adipose stem cells by tumour necrosis factor-α preconditioning for bone regeneration

scientific article published in August 2013

Activation of the pro-migratory bone morphogenetic protein receptor 1B gene in human MDA-MB-468 triple-negative breast cancer cells that over-express CYP2J2.

scientific article published on 05 October 2016

Adenoviral delivery of osteoprotegerin ameliorates bone resorption in a mouse ovariectomy model of osteoporosis

scientific article

Adult osteosclerosis

scientific article published on 01 January 1983

Aluminium-related bone disease presenting with calcaneal stress fractures

scientific article published on 01 March 1993

Aluminum and renal bone disease in Australia

scientific article published on 01 February 1986

Baghdadite ceramics modulate the cross talk between human adipose stem cells and osteoblasts for bone regeneration

scientific article published on 14 December 2013

Biphasic glucocorticoid-dependent regulation of Wnt expression and its inhibitors in mature osteoblastic cells

scientific article published on 30 October 2009

Bone balance within a cortical BMU: local controls of bone resorption and formation.

scientific article published on 23 July 2012

Bone death in hip fracture in the elderly

scientific article published on 01 November 1990

Bone death in transient regional osteoporosis

scientific article published in January 1992

Bone growth is enhanced by novel bioceramic coatings on Ti alloy implants

scientific article

Bone loss after liver transplantation

scientific article published in October 1991

Bone metabolism in chronic renal failure

scientific article published on 01 April 1982

Bone metabolism in idiopathic juvenile osteoporosis: a case report

scientific article published on 01 January 1983

Bone metabolism in systemic mastocytosis. A case report

scientific article published on 01 April 1981

Bone morphogenetic protein 2 (BMP-2) enhances BMP-3, BMP-4, and bone cell differentiation marker gene expression during the induction of mineralized bone matrix formation in cultures of fetal rat calvarial osteoblasts

scientific article published on 01 March 1997

Bone resorption caused by three periodontal pathogens in vivo in mice is mediated in part by prostaglandin.

scientific article

Bone resorption increases tumour growth in a mouse model of osteosclerotic breast cancer metastasis

scientific article published on 18 April 2008

Burning daylight: balancing vitamin D requirements with sensible sun exposure

scientific article published on 01 April 2011

CXCL12/CXCR4 axis in tissue targeting and bone destruction in cancer and multiple myeloma

scientific article published on July 2009

Calcification in atherosclerosis: bone biology and chronic inflammation at the arterial crossroads.

scientific article

Cellular activity and signaling induced by osteoprotegerin in osteoclasts: involvement of receptor activator of nuclear factor kappaB ligand and MAPK.

scientific article published on February 2004

Characterisation of a novel light activated adhesive scaffold: Potential for device attachment.

scientific article published on 27 May 2016

Characterization of osteoclast precursors in human blood

scientific article published on 01 November 2000

Clinical review 165: Markers of bone remodeling in metastatic bone disease.

scientific article published on November 2003

Colonic dendritic cells, intestinal inflammation, and T cell-mediated bone destruction are modulated by recombinant osteoprotegerin

scientific article published in December 2003

Combined treatment with PTH (1-34) and OPG increases bone volume and uniformity of mineralization in aged ovariectomized rats.

scientific article published in July 2005

Computational modeling of interactions between multiple myeloma and the bone microenvironment

scientific article

Correction: The 18 kDa Translocator Protein (Peripheral Benzodiazepine Receptor) Expression in the Bone of Normal, Osteoprotegerin or Low Calcium Diet Treated Mice.

scientific article published on 8 October 2012

Correlates of osteoprotegerin levels in women and men.

scientific article published in May 2002

Corticosterone selectively targets endo-cortical surfaces by an osteoblast-dependent mechanism

scientific article published on 22 June 2011

Direct crosstalk between cancer and osteoblast lineage cells fuels metastatic growth in bone via auto-amplification of IL-6 and RANKL signaling pathways.

scientific article published on September 2014

E-cadherin expression in human breast cancer cells suppresses the development of osteolytic bone metastases in an experimental metastasis model

scientific article published on 01 September 1996

Effect of EstrogenversusTestosterone on Circulating Osteoprotegerin and Other Cytokine Levels in Normal Elderly Men

Effect of aluminum and parathyroid hormone on osteoblasts and bone mineralization in chronic renal failure.

scientific article

Effect of aluminum on normal and uremic rats: tissue distribution, vitamin D metabolites, and quantitative bone histology

scientific article published on 01 May 1983

Effect of estrogen versus testosterone on circulating osteoprotegerin and other cytokine levels in normal elderly men.

scientific article

Effect of osteoprotegerin and pamidronate treatment in transgenic mice overexpressing human TNF.

scientific article published on 26 January 2001

Effects of human tumor cell lines on local new bone formation in vivo

scientific article published on 01 February 1997

Effects of immunosuppressants on receptor activator of NF-kappaB ligand and osteoprotegerin production by human osteoblastic and coronary artery smooth muscle cells

scientific article

Efficacy of novel synthetic bone substitutes in the reconstruction of large segmental bone defects in sheep tibiae

scientific article published on 19 February 2016

Endogenous glucocorticoid signalling in osteoblasts is necessary to maintain normal bone structure in mice.

scientific article

Estrogen stimulates gene expression and protein production of osteoprotegerin in human osteoblastic cells

scientific article published on 01 September 1999

Evidence for anti-osteoporosis therapy in acute fracture situations--recommendations of a multidisciplinary workshop of the International Society for Fracture Repair

scientific article published on 13 October 2009

Evidence that type I osteoporosis results from enhanced responsiveness of bone to estrogen deficiency.

scientific article published on 18 July 2003

Fibroblast growth factor 23: a phosphatonin regulating phosphate homeostasis?

scientific article published on July 2004

Follicle-stimulating hormone increases bone mass in female mice

scientific article

Fracture behaviors of ceramic tissue scaffolds for load bearing applications.

scientific article published on 12 July 2016

Genetic and hormonal control of bone volume, architecture, and remodeling in XXY mice

scientific article

Glucocorticoid-dependent Wnt signaling by mature osteoblasts is a key regulator of cranial skeletal development in mice

scientific article published in February 2009

Growth and dissemination of a newly-established murine B-cell lymphoma cell line is inhibited by multimeric YIGSR peptide.

scientific article published on October 1998

Growth retardation and renal osteodystrophy in children with chronic renal failure

scientific article published on 01 November 1983

Histomorphological and torque removal comparison of 6 mm orthodontic miniscrews with and without surface treatment in New Zealand rabbits

scientific article published on 21 January 2015

Human amniotic tumor that induces new bone formation in vivo produces growth-regulatory activity in vitro for osteoblasts identified as an extended form of basic fibroblast growth factor

scientific article published on February 1996

Hypothesis: bones toughness arises from the suppression of elastic waves

scientific article

Immobilisation hypercalcemia

scientific article published on 01 January 1984

Immobilization hypercalcaemia due to low bone formation and responding to intravenous sodium sulphate

scientific article published on May 1986

Increased bone formation in osteocalcin-deficient mice.

scientific article published on August 1996

Inhibition of bone resorption, rather than direct cytotoxicity, mediates the anti-tumour actions of ibandronate and osteoprotegerin in a murine model of breast cancer bone metastasis.

scientific article published on 7 November 2006

Inhibition of osteolytic bone metastasis of breast cancer by combined treatment with the bisphosphonate ibandronate and tissue inhibitor of the matrix metalloproteinase-2.

scientific article published on May 1997

Interleukin-1beta and tumor necrosis factor-alpha, but not interleukin-6, stimulate osteoprotegerin ligand gene expression in human osteoblastic cells

scientific article published on September 1999

Isolated and combined inhibition of TNF-, IL-1 and RANKL-pathways in TNF-induced arthritis: effects on synovial inflammation, bone erosion and cartilage destruction

Lack of metabolic bone disease in patients with fracture of the femoral neck

scientific article published on 01 April 1981

Long-term experience with a calcium-thiazide treatment for Paget's disease of bone

scientific article published on 01 December 1982

Mathematical modeling of postmenopausal osteoporosis and its treatment by the anti-catabolic drug denosumab.

scientific article

Measurement of osteoclasts and bone resorption by automated image analysis

scientific article published in February 1993

Mechanisms of disease: roles of OPG, RANKL and RANK in the pathophysiology of skeletal metastasis.

scientific article

Metabolic studies in kidney stone disease

scientific article published on March 1992

Mitogenic lectin concanavalin A induces calvarial bone formation in vivo via indomethacin-sensitive pathway

scientific article published on 01 February 1997

Model structure and control of bone remodeling: a theoretical study.

scientific article

OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized rats

scientific article published in October 2001

OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis

scientific journal article

Osteoblast-targeted disruption of glucocorticoid signalling does not delay intramembranous bone healing.

scientific article

Osteoblasts mediate the adverse effects of glucocorticoids on fuel metabolism.

scientific article

Osteocyte death and hip fracture

scientific article

Osteoprotegerin ameliorates sciatic nerve crush induced bone loss

scientific article published on 01 July 2001

Osteoprotegerin and osteoprotegerin ligand effects on osteoclast formation from human peripheral blood mononuclear cell precursors

scientific article published on February 1999

Osteoprotegerin differentially regulates protease expression in osteoclast cultures

scientific article published on 26 April 2002

Osteoprotegerin inhibits osteolysis and decreases skeletal tumor burden in syngeneic and nude mouse models of experimental bone metastasis

scientific article

Osteoprotegerin inhibits the development of osteolytic bone disease in multiple myeloma

scientific article published on 01 December 2001

Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation

scientific article

Osteoprotegerin mitigates tail suspension-induced osteopenia

scientific article published on 01 May 2000

Osteoprotegerin prevents and reverses hypercalcemia in a murine model of humoral hypercalcemia of malignancy.

scientific article published on February 2000

Osteoprotegerin production by human osteoblast lineage cells is stimulated by vitamin D, bone morphogenetic protein-2, and cytokines

scientific article published on September 1998

Osteoprotegerin protects against generalized bone loss in tumor necrosis factor-transgenic mice

scientific article published in July 2003

Osteoprotegerin protects from generalized bone loss in TNF-transgenic mice.

scientific article published on 24 February 2003

Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis

scientific article published on October 2002

Osteoprotegerin reverses osteoporosis by inhibiting endosteal osteoclasts and prevents vascular calcification by blocking a process resembling osteoclastogenesis

scientific article

Osteoprotegerin: a novel secreted protein involved in the regulation of bone density

scientific article

Pathologic fracture due to severe osteomalacia following low-dose diphosphonate treatment of Paget's disease of bone

scientific article published on 01 June 1983

Priming Adipose Stem Cells with Tumor Necrosis Factor-Alpha Preconditioning Potentiates Their Exosome Efficacy for Bone Regeneration.

scientific article published on 23 March 2017

Prurigo nodularis and aluminium overload in maintenance haemodialysis

scientific article

Quantitative bone histology in children with chronic renal failure

scientific article published on 01 June 1982

Quantitative bone histology in end-stage renal failure

scientific article published on 01 January 1980

Quantitative bone histology in the hypercalcemia of malignant disease

scientific article published on 01 December 1982

RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolism

scientific article published on February 2000

RANK ligand

scientific article published on 23 November 2006

Rationale for the role of osteoclast-like cells in arterial calcification

scientific article published in April 2002

Recovery from steroid-induced osteoporosis

scientific article published in September 1987

Regulation of osteoclast protease expression by RANKL.

scientific article published in October 2003

Repairing a critical-sized bone defect with highly porous modified and unmodified baghdadite scaffolds

scientific article published on 27 July 2012

Role of mathematical modeling in bone fracture healing.

scientific article

Serum cathepsin K concentrations reflect osteoclastic activity in women with postmenopausal osteoporosis and patients with Paget's disease.

scientific article published in January 2006

Serum osteoprotegerin levels are increased in patients with advanced prostate cancer

scientific article

Serum osteoprotegerin levels in healthy controls and cancer patients

scientific article published on 01 July 2002

Sex Steroids, Not FSH, Influence Bone Mass

scientific article published on 01 December 2006

Short-Term Exposure to Tumor Necrosis Factor-Alpha Enables Human Osteoblasts to Direct Adipose Tissue-Derived Mesenchymal Stem Cells into Osteogenic Differentiation ⬇️

scientific article published on March 6, 2012

Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction

scientific article published on 01 January 2004

Sphene ceramics for orthopedic coating applications: an in vitro and in vivo study.

scientific article

Stimulation of osteoprotegerin ligand and inhibition of osteoprotegerin production by glucocorticoids in human osteoblastic lineage cells: potential paracrine mechanisms of glucocorticoid-induced osteoporosis

scientific article published on October 1999

Suramin suppresses hypercalcemia and osteoclastic bone resorption in nude mice bearing a human squamous cancer

scientific article published on 01 May 1995

Sustained antiresorptive effects after a single treatment with human recombinant osteoprotegerin (OPG): a pharmacodynamic and pharmacokinetic analysis in rats.

scientific article

Systemic administration of acidic fibroblast growth factor (FGF-1) prevents bone loss and increases new bone formation in ovariectomized rats

scientific article published on June 1999

TRAF6 deficiency results in osteopetrosis and defective interleukin-1, CD40, and LPS signaling

scientific journal article

Targeting IL-6 and RANKL signaling inhibits prostate cancer growth in bone

scientific article published on 16 September 2014

The 18 kDa translocator protein (peripheral benzodiazepine receptor) expression in the bone of normal, osteoprotegerin or low calcium diet treated mice

scientific article

The bone remodeling environment is a factor in breast cancer bone metastasis.

scientific article published on 21 May 2010

The challenge of continuous exogenous glucocorticoid administration in mice.

scientific article

The determination of bone viability: a histochemical method for identification of lactate dehydrogenase activity in osteocytes in fresh calcified and decalcified sections of human bone

scientific article published in October 1982

The effect of a single dose of osteoprotegerin in postmenopausal women

scientific article

The effect of age on bone composition and viability in the femoral head

scientific article published on 01 February 1985

The effect of long-term low-dose diphosphonate treatment on rat bone

scientific article published on 01 May 1982

The effect of low-dose cyclical etidronate and calcium on bone mass in early postmenopausal women

scientific article published on 01 March 1993

The effect of osteoprotegerin administration on the intra-tibial growth of the osteoblastic LuCaP 23.1 prostate cancer xenograft

scientific article published on 01 January 2004

The effectiveness of a soluble calcium preparation as a gut phosphate binder

scientific article published on 01 September 1988

The effects of cytokines and growth factors on osteoblastic cells

scientific article published on August 1995

The effects of osteoprotegerin on the mechanical properties of rat bone

scientific article published on 01 July 2001

The expression of osteoprotegerin and RANK ligand and the support of osteoclast formation by stromal-osteoblast lineage cells is developmentally regulated

scientific article

The inhibition of RANKL causes greater suppression of bone resorption and hypercalcemia compared with bisphosphonates in two models of humoral hypercalcemia of malignancy.

scientific article

The ligand for osteoprotegerin (OPGL) directly activates mature osteoclasts.

scientific article published on May 1999

The pathogenesis of idiopathic hypercalciuria: evidence for parathyroid hyperfunction.

scientific article published in January 1984

The pathogenesis of osteoarthritis of the hip. Evidence for primary osteocyte death

scientific article published on 01 January 1987

The pathogenesis of renal osteodystrophy: role of vitamin D, aluminium, parathyroid hormone, calcium and phosphorus

The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction

scientific article published on 01 June 2006

The receptor activator of nuclear factor-kappaB ligand inhibitor osteoprotegerin is a bone-protective agent in a rat model of chronic renal insufficiency and hyperparathyroidism.

scientific article published on 5 December 2005

The role of the bone microenvironment in skeletal metastasis.

scientific article

The roles of osteoprotegerin and osteoprotegerin ligand in the paracrine regulation of bone resorption.

scientific article

The vitamin D receptor is involved in the regulation of human breast cancer cell growth via a ligand-independent function in cytoplasm

scientific article

Theoretical investigation of the role of the RANK-RANKL-OPG system in bone remodeling.

scientific article published on 25 September 2009

Therapy insight: the risks and benefits of bisphosphonates for the treatment of tumor-induced bone disease.

scientific article

Transgenic disruption of glucocorticoid signaling in mature osteoblasts and osteocytes attenuates K/BxN mouse serum-induced arthritis in vivo.

scientific article published in July 2009

Treatment of Paget's disease of bone with a combination of intranasal salmon calcitonin and oral calcium and thiazide

scientific article (publication date: September 1991)

Treatment of childhood renal osteodystrophy with calcitriol or ergocalciferol

scientific article published on 01 October 1985

Treatment of hemodialysis bone disease with 24,25-(OH)2D3 and 1,25-(OH)2D3 alone or in combination

scientific article published on 01 January 1985

Tumor necrosis factor alpha-mediated joint destruction is inhibited by targeting osteoclasts with osteoprotegerin

scientific article published in March 2002

Tumor necrosis factor enhances parathyroid hormone-related protein-induced hypercalcemia and bone resorption without inhibiting bone formation in vivo

scientific article

Tumor necrosis factor receptor family member RANK mediates osteoclast differentiation and activation induced by osteoprotegerin ligand

scientific article

Unique microstructural design of ceramic scaffolds for bone regeneration under load.

scientific article

Vitamin D deficiency promotes growth of MCF-7 human breast cancer in a rodent model of osteosclerotic bone metastasis

scientific article published on 16 July 2010

Vitamin D deficiency promotes human breast cancer growth in a murine model of bone metastasis

scientific article

Vitamin D deficiency promotes prostate cancer growth in bone

scientific article published on 28 December 2010

Vitamin D supplements and bone mineral density

Zirconium ions up-regulate the BMP/SMAD signaling pathway and promote the proliferation and differentiation of human osteoblasts

scientific article published on 20 January 2015

osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification

scientific article

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