List of works - Christopher Gordon

An efficient continuous flow approach to furnish furan-based biaryls

scientific article published on 21 October 2014

Anti-malarial, anti-algal, anti-tubercular, anti-bacterial, anti-photosynthetic, and anti-fouling activity of diterpene and diterpene isonitriles from the tropical marine sponge Cymbastela hooperi

scientific article published on 2 November 2010

Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.

scientific article published on 22 January 2013

Calcineurin activity is required for the completion of cytokinesis

scientific article

Control of HIV through the inhibition of HIV-1 integrase: a medicinal chemistry perspective.

scientific article published on March 2007

Control of hepatitis C: a medicinal chemistry perspective

scientific article

Cytotoxicity of a Series of Norcantharidin-Inspired Tetrahydroepoxyisoindole Carboxamides.

scientific article published on 06 December 2016

Defining the mechanisms by which the reactive oxygen species by-product, 4-hydroxynonenal, affects human sperm cell function

scientific article published on 11 February 2015

Development of second-generation indole-based dynamin GTPase inhibitors

scientific article

Discovery of acrylonitrile-based small molecules active against Haemonchus contortus

Efficient phosphine-mediated formal C(sp3)-C(sp3) coupling reactions of alkyl halides in batch and flow.

scientific article

Hedgehog signalling pathway inhibitors as cancer suppressing agents

Identification and validation of small molecule modulators of the NusB-NusE interaction.

scientific article

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis

scientific article

Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization

scientific article published on 13 April 2020

Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells

scientific article published on 12 July 2011

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles

scientific article

Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction

scientific article published on 01 March 2011

Norcantharidin analogues with nematocidal activity in Haemonchus contortus

scientific article published on 13 April 2011

Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition

scientific article

Norcantharimide analogues possessing terminal phosphate esters and their anti-cancer activity ⬇️

scientific article published on September 15, 2011

Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors

scientific article published on 7 June 2016

Small molecule Hedgehog pathway antagonists

scientific article

Small-Molecule Inhibitors of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity

scientific article published on 25 July 2017

Structure-Activity Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator

scientific article published on 14 November 2019

Synthesis and Cytotoxicity of Octahydroepoxyisoindole-7-carboxylic Acids and Norcantharidin-Amide Hybrids as Norcantharidin Analogues

scientific article published on 14 May 2019

Synthetic strategies to access staphylococcus auto-inducing peptides as quorum sensing modulators

scientific article published on 01 January 2020

The antiplasmodial activity of norcantharidin analogs.

scientific article published on 7 September 2010

The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction.

scientific article

The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells

scientific article published on 22 June 2010

The expanding utility of continuous flow hydrogenation

scientific article published on 15 June 2015

The pthaladyns: GTP competitive inhibitors of dynamin I and II GTPase derived from virtual screening

scientific article

The renascence of continuous-flow peptide synthesis - an abridged account of solid and solution-based approaches

scientific article published on 01 January 2018

Transition Metal Intercalators as Anticancer Agents-Recent Advances

scientific article

List of works by Christopher Gordon

An efficient continuous flow approach to furnish furan-based biaryls

Anti-malarial, anti-algal, anti-tubercular, anti-bacterial, anti-photosynthetic, and anti-fouling activity of diterpene and diterpene isonitriles from the tropical marine sponge Cymbastela hooperi

Attenuating Staphylococcus aureus virulence gene regulation: a medicinal chemistry perspective.

Calcineurin activity is required for the completion of cytokinesis

Control of HIV through the inhibition of HIV-1 integrase: a medicinal chemistry perspective.

Control of hepatitis C: a medicinal chemistry perspective

Cytotoxicity of a Series of Norcantharidin-Inspired Tetrahydroepoxyisoindole Carboxamides.

Defining the mechanisms by which the reactive oxygen species by-product, 4-hydroxynonenal, affects human sperm cell function

Development of second-generation indole-based dynamin GTPase inhibitors

Discovery of acrylonitrile-based small molecules active against Haemonchus contortus

Efficient phosphine-mediated formal C(sp3)-C(sp3) coupling reactions of alkyl halides in batch and flow.

Hedgehog signalling pathway inhibitors as cancer suppressing agents

Identification and validation of small molecule modulators of the NusB-NusE interaction.

Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis

Immobilized Carbodiimide Assisted Flow Combinatorial Protocol to Facilitate Amide Coupling and Lactamization

Inhibition of dynamin by dynole 34-2 induces cell death following cytokinesis failure in cancer cells

Inhibition of dynamin mediated endocytosis by the dynoles--synthesis and functional activity of a family of indoles

Investigation of the one-pot synthesis of quinolin-2-(1H)-ones and the discovery of a variation of the three-component Ugi reaction

Norcantharidin analogues with nematocidal activity in Haemonchus contortus

Norcantharidin analogues: synthesis, anticancer activity and protein phosphatase 1 and 2A inhibition

Norcantharimide analogues possessing terminal phosphate esters and their anti-cancer activity ⬇️

Quinolone-1-(2H)-ones as hedgehog signalling pathway inhibitors

Small molecule Hedgehog pathway antagonists

Small-Molecule Inhibitors of the NusB-NusE Protein-Protein Interaction with Antibiotic Activity

Structure-Activity Relationship Studies of Small Molecule Modulators of the Staphylococcal Accessory Gene Regulator

Synthesis and Cytotoxicity of Octahydroepoxyisoindole-7-carboxylic Acids and Norcantharidin-Amide Hybrids as Norcantharidin Analogues

Synthetic strategies to access staphylococcus auto-inducing peptides as quorum sensing modulators

The antiplasmodial activity of norcantharidin analogs.

The discovery of allyltyrosine based tripeptides as selective inhibitors of the HIV-1 integrase strand-transfer reaction.

The dynamin inhibitors MiTMAB and OcTMAB induce cytokinesis failure and inhibit cell proliferation in human cancer cells

The expanding utility of continuous flow hydrogenation

The pthaladyns: GTP competitive inhibitors of dynamin I and II GTPase derived from virtual screening

The renascence of continuous-flow peptide synthesis - an abridged account of solid and solution-based approaches

Transition Metal Intercalators as Anticancer Agents-Recent Advances