List of works by Katie Lunnon

A Pathway Based Classification Method for Analyzing Gene Expression for Alzheimer's Disease Diagnosis

scientific article published on 15 October 2015

A blood gene expression marker of early Alzheimer's disease

scientific article published on January 2013

A comparison of mitochondrial DNA isolation methods in frozen post-mortem human brain tissue--applications for studies of mitochondrial genetics in brain disorders

scientific article

A cross-brain regions study of ANK1 DNA methylation in different neurodegenerative diseases

A data-driven approach to preprocessing Illumina 450K methylation array data

scientific article

A five-year update on epigenome-wide association studies of DNA modifications in Alzheimer's disease: progress, practicalities and promise

scientific article published on 03 August 2020

A histone acetylome-wide association study of Alzheimer's disease identifies disease-associated H3K27ac differences in the entorhinal cortex

scientific article published on 22 October 2018

A novel multi-tissue RNA diagnostic of healthy ageing relates to cognitive health status

scientific article

ABCA7 p.G215S as potential protective factor for Alzheimer's disease

scientific article published on 20 April 2016

ANK1 is up-regulated in laser captured microglia in Alzheimer's brain; the importance of addressing cellular heterogeneity.

scientific article

Alpha-synuclein deficiency in the C57BL/6JOlaHsd strain does not modify disease progression in the ME7-model of prion disease

scientific article published on 30 October 2009

Altered DNA methylation profiles in blood from patients with sporadic Creutzfeldt-Jakob disease

scientific article published on 12 September 2020

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

scientific article published on 21 September 2013

Alzheimer's disease-associated (hydroxy)methylomic changes in the brain and blood

scientific article published on 27 November 2019

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

scientific article

Applying gene-editing technology to elucidate the functional consequence of genetic and epigenetic variation in Alzheimer's disease

scientific article published on 12 July 2020

Association of plasma clusterin concentration with severity, pathology, and progression in Alzheimer disease

scientific article

Blood methylomic signatures of presymptomatic dementia in elderly subjects with type 2 diabetes mellitus

scientific article published on 24 December 2014

Central and systemic endotoxin challenges exacerbate the local inflammatory response and increase neuronal death during chronic neurodegeneration.

scientific article

Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt-PCP-JNK pathway

scientific article

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.

scientific article

DNA Modifications and Alzheimer's Disease.

scientific article published in January 2017

Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

article

Epigenetic dysregulation of brainstem nuclei in the pathogenesis of Alzheimer's disease: looking in the correct place at the right time?

scientific article published on 14 September 2016

Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease

scientific article

Epigenetic regulation of mitochondrial function in neurodegenerative disease: New insights from advances in genomic technologies

scientific article published on 10 February 2016

Epigenetic studies in Alzheimer's disease: current findings, caveats, and considerations for future studies

scientific article published on 13 September 2013

Epigenetics and DNA methylomic profiling in Alzheimer's disease and other neurodegenerative diseases.

scientific article published on 14 August 2017

Erratum to: Variation in 5-hydroxymethylcytosine across human cortex and cerebellum

scientific article published on 17 June 2016

Exome sequencing identifies 2 novel presenilin 1 mutations (p.L166V and p.S230R) in British early-onset Alzheimer's disease

scientific article

Functional annotation of the human brain methylome identifies tissue-specific epigenetic variation across brain and blood

scientific article

Genetic architecture of epigenetic and neuronal ageing rates in human brain regions

scientific article

Genetic variants near MLST8 and DHX57 affect the epigenetic age of the cerebellum

scientific article

Genome-wide analysis of genetic correlation in dementia with Lewy bodies, Parkinson's and Alzheimer's diseases

scientific article published on 2 November 2015

Genome-wide association with MRI atrophy measures as a quantitative trait locus for Alzheimer's disease.

scientific article published on 30 November 2010

Identification of cis-regulatory variation influencing protein abundance levels in human plasma.

scientific article published on 16 May 2012

Increased DNA methylation near TREM2 is consistently seen in the superior temporal gyrus in Alzheimer's disease brain

scientific article

Inflammatory proteins in plasma are associated with severity of Alzheimer's disease

scientific article

Influence of Coding Variability in APP-Aβ Metabolism Genes in Sporadic Alzheimer's Disease

scientific article

Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

scientific article published on 12 October 2015

Longitudinal analyses of the DNA methylome in deployed military servicemen identify susceptibility loci for post-traumatic stress disorder

scientific article

Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3.

scientific article published on 2 February 2018

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

scientific article

Mis-expression of the Alzheimer’s disease associated gene Ankyrin causes memory loss and shortened lifespan in Drosophila

article

Mitochondrial dysfunction and immune activation are detectable in early Alzheimer's disease blood

scientific article published on January 2012

Mitochondrial genes are altered in blood early in Alzheimer's disease

scientific article

Neuroepigenetics of Aging and Age-Related Neurodegenerative Disorders

scientific article published on 05 June 2018

No Evidence to Suggest that the Use of Acetylcholinesterase Inhibitors Confounds the Results of Two Blood-Based Biomarker Studies in Alzheimer's Disease

scientific article published in August 2015

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer's disease

scientific article published on 21 March 2019

Peripheral DNA methylation, cognitive decline and brain aging: pilot findings from the Whitehall II imaging study

scientific article published on 25 April 2018

Plasma based markers of [11C] PiB-PET brain amyloid burden

scientific article

Plasma proteins predict conversion to dementia from prodromal disease

scientific article

Psychosis-associated DNA methylomic variation in Alzheimer's disease cortex

scientific article published on 08 January 2020

Regional differences in mitochondrial DNA methylation in human post-mortem brain tissue

scientific article

Systemic Inflammation Modulates Fc Receptor Expression on Microglia during Chronic Neurodegeneration

scientific article published on 13 May 2011

Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease

scientific article published on 18 September 2008

The Molecular Etiology of Alzheimer's disease

scientific article published on 12 July 2020

The mitochondrial epigenome: a role in Alzheimer's disease?

scientific article published on January 2014

Tissue-specific patterns of allelically-skewed DNA methylation

scientific article published on 19 January 2016

Using induced pluripotent stem cells to explore genetic and epigenetic variation associated with Alzheimer's disease.

scientific article published on 3 October 2017

Variation in 5-hydroxymethylcytosine across human cortex and cerebellum.

scientific article published on 16 February 2016

Which Risk Factors Causally Influence Dementia? A Systematic Review of Mendelian Randomization Studies.

scientific article published in January 2018

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