List of works - Florian Muller

A critical evaluation of cpYFP as a probe for superoxide

scientific article published on 22 September 2009

Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy

scientific journal article

Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment

scientific article published on 23 June 2020

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging

scientific article published on 06 January 2006

An inhibitor of oxidative phosphorylation exploits cancer vulnerability

scientific article published on 11 June 2018

Architecture of the Qo site of the cytochrome bc1 complex probed by superoxide production

scientific article published in June 2003

Author Correction: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

scientific article published on 01 October 2018

Collateral Lethality: A new therapeutic strategy in oncology

scientific article

Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels ⬇️

scientific article published on May 18, 2012

Complex III releases superoxide to both sides of the inner mitochondrial membrane

scientific journal article

Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity.

scientific article published on 23 September 2009

Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance

scientific article published in July 2008

Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production

scientific article published on 20 June 2007

Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.

scientific article

Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS

scientific article (publication date: August 2012)

ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase

scientific article

Erratum: Corrigendum: Passenger deletions generate therapeutic vulnerabilities in cancer

scientific article published in Nature

FOXO protects against age-progressive axonal degeneration

scientific article published on 26 November 2017

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

scientific article

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation

scientific article published on 01 January 2019

Functional regulation of FoxO1 in neural stem cell differentiation

scientific article published on 16 October 2015

GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis

scientific article published on 6 August 2008

Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

scientific article

H(2)S-induced ectothermy: relevance to aging

scientific article

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

scientific article published on 6 September 2017

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

scientific article

Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

scientific article

Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo

scientific article published on 21 November 2019

Mitochondrial 'flashes': a radical concept repHined.

scientific article published on 20 August 2012

MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models

scientific article

Multiple Q-cycle bypass reactions at the Qo site of the cytochrome bc1 complex

scientific article

Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

scientific article published on 11 June 2018

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

scientific article

Passenger deletions generate therapeutic vulnerabilities in cancer

scientific article

Q-cycle bypass reactions at the Qo site of the cytochrome bc1 (and related) complexes

scientific article

Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in intact biological specimens

scientific article published on 25 June 2020

SF2312 is a natural phosphonate inhibitor of enolase

scientific article

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

scientific article published on 8 February 2017

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

scientific article

Telomere dysfunction induces metabolic and mitochondrial compromise.

scientific article

The 'mitoflash' probe cpYFP does not respond to superoxide

scientific article published in October 2014

The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues

scientific article published on 09 July 2019

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.

scientific article published on 18 December 2017

The in vivo gene expression signature of oxidative stress

scientific article

The nature and mechanism of superoxide production by the electron transport chain: Its relevance to aging ⬇️

scientific article published on October 1, 2000

Trends in oxidative aging theories

scientific article (publication date: 15 August 2007)

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

scientific article published in July 2017

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution

scientific article

List of works by Florian Muller

A critical evaluation of cpYFP as a probe for superoxide

Absence of CuZn superoxide dismutase leads to elevated oxidative stress and acceleration of age-dependent skeletal muscle atrophy

Advantages of the Parent Nucleoside GS-441524 over Remdesivir for Covid-19 Treatment

Alterations in mitochondrial function, hydrogen peroxide release and oxidative damage in mouse hind-limb skeletal muscle during aging

An inhibitor of oxidative phosphorylation exploits cancer vulnerability

Architecture of the Qo site of the cytochrome bc1 complex probed by superoxide production

Author Correction: Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

Collateral Lethality: A new therapeutic strategy in oncology

Complex I generated, mitochondrial matrix-directed superoxide is released from the mitochondria through voltage dependent anion channels ⬇️

Complex III releases superoxide to both sides of the inner mitochondrial membrane

Conditional knockout of Mn-SOD targeted to type IIB skeletal muscle fibers increases oxidative stress and is sufficient to alter aerobic exercise capacity.

Deleterious action of FA metabolites on ATP synthesis: possible link between lipotoxicity, mitochondrial dysfunction, and insulin resistance

Denervation-induced skeletal muscle atrophy is associated with increased mitochondrial ROS production

Dietary restriction attenuates age-associated muscle atrophy by lowering oxidative stress in mice even in complete absence of CuZnSOD.

Dietary restriction but not rapamycin extends disease onset and survival of the H46R/H48Q mouse model of ALS

ENOblock Does Not Inhibit the Activity of the Glycolytic Enzyme Enolase

Erratum: Corrigendum: Passenger deletions generate therapeutic vulnerabilities in cancer

FOXO protects against age-progressive axonal degeneration

FoxOs cooperatively regulate diverse pathways governing neural stem cell homeostasis

Functional Genomics Reveals Synthetic Lethality between Phosphogluconate Dehydrogenase and Oxidative Phosphorylation

Functional regulation of FoxO1 in neural stem cell differentiation

GAPDH is conformationally and functionally altered in association with oxidative stress in mouse models of amyotrophic lateral sclerosis

Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer

H(2)S-induced ectothermy: relevance to aging

HSP90 inhibition enhances cancer immunotherapy by upregulating interferon response genes

High rates of superoxide production in skeletal-muscle mitochondria respiring on both complex I- and complex II-linked substrates

Increased superoxide in vivo accelerates age-associated muscle atrophy through mitochondrial dysfunction and neuromuscular junction degeneration

Mechanism-Specific Pharmacodynamics of a Novel Complex-I Inhibitor Quantified by Imaging Reversal of Consumptive Hypoxia with [18F]FAZA PET In Vivo

Mitochondrial 'flashes': a radical concept repHined.

MnSOD deficiency has a differential effect on disease progression in two different ALS mutant mouse models

Multiple Q-cycle bypass reactions at the Qo site of the cytochrome bc1 complex

Mutations in the SWI/SNF complex induce a targetable dependence on oxidative phosphorylation in lung cancer

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

Passenger deletions generate therapeutic vulnerabilities in cancer

Q-cycle bypass reactions at the Qo site of the cytochrome bc1 (and related) complexes

Robust detection of oncometabolic aberrations by 1H-13C heteronuclear single quantum correlation in intact biological specimens

SF2312 is a natural phosphonate inhibitor of enolase

Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer.

Telomerase reactivation reverses tissue degeneration in aged telomerase-deficient mice

Telomere dysfunction induces metabolic and mitochondrial compromise.

The 'mitoflash' probe cpYFP does not respond to superoxide

The 3S Enantiomer Drives Enolase Inhibitory Activity in SF2312 and Its Analogues

The Effect of Topoisomerase I Inhibitors on the Efficacy of T-Cell-Based Cancer Immunotherapy.

The in vivo gene expression signature of oxidative stress

The nature and mechanism of superoxide production by the electron transport chain: Its relevance to aging ⬇️

Trends in oxidative aging theories

Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment.

Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution