List of works - Manjunath Ghate

3D QSAR studies on substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonist.

scientific article published in September 2013

3D QSAR-based design and liquid phase combinatorial synthesis of 1,2-disubstituted benzimidazole-5-carboxylic acid and 3-substituted-5H-benzimidazo[1,2-d][1,4]benzodiazepin-6(7H)-one derivatives as anti-mycobacterial agents

scientific article published on 22 March 2019

Benzopyran derivatives as cardio-selective ATP-sensitive potassium channel openers: a review

scientific article published on October 2013

CoMFA and CoMSIA studies on aryl carboxylic acid amide derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors

scientific article published in December 2012

CoMFA and CoMSIA studies onC-aryl glucoside SGLT2 inhibitors as potential anti-diabetic agents ⬇️

scientific article published on January 11, 2013

Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors

scientific article published on 6 March 2017

Design, synthesis and docking studies of some novel (R)-2-(4'-chlorophenyl)-3-(4'-nitrophenyl)-1,2,3,5-tetrahydrobenzo[4,5] imidazo [1,2-c]pyrimidin-4-ol derivatives as antitubercular agents

scientific article published on 11 June 2014

Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents.

scientific article

Design, synthesis, pharmacological evaluation and in silico ADMET prediction of novel substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonists based on predictive 3D QSAR models

scientific article published on 05 March 2014

Development of docking-based 3D QSAR models for the design of substituted quinoline derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors

scientific article published on 28 May 2013

Homology modeling a fast tool for drug discovery: current perspectives

scientific article

Homology modeling, binding site identification and docking study of human angiotensin II type I (Ang II-AT1) receptor

scientific article

Identification of novel PfDHODH inhibitors as antimalarial agents via pharmacophore-based virtual screening followed by molecular docking and in vivo antimalarial activity

scientific article published on 16 June 2016

Ligand and structure-based approaches for the identification of SIRT1 activators.

scientific article

Liquid-phase combinatorial library synthesis: recent advances and future perspectives.

scientific article

Molecular modeling study for the design of novel acetyl-CoA carboxylase inhibitors using 3D QSAR, molecular docking and dynamic simulations.

scientific article published on 23 June 2016

Novel anticancer agents and targets: recent advances and future perspectives

scientific article published on July 2013

Pharmacophore modeling, virtual screening, docking and in silico ADMET analysis of protein kinase B (PKB β) inhibitors ⬇️

scientific article published on February 24, 2013

Pharmacophore-based identification and in vitro validation of apoptosis inducers as anticancer agents

scientific article published on 01 November 2020

QSAR study on a series of aryl carboxylic acid amide derivatives as potential inhibitors of dihydroorotate dehydrogenase (DHODH)

scientific article published on 01 March 2013

Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors.

scientific article published on 11 January 2014

Structure based lead optimization approach in discovery of selective DPP4 inhibitors

scientific article published on May 2013

Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation

scientific article (publication date: 2013)

Substituted Benzimidazole Derivatives as Angiotensin II -AT1 Receptor Antagonist: A Review ⬇️

scientific article published on December 1, 2010

Synthesis and QSAR modeling of novel benzimidazolo thiazolidinones, thiazinones and 5-arylidene-2-imino thiazolidinones as antibacterial agents.

scientific article published in May 2013

Synthesis of vanillin ethers from 4-(bromomethyl) coumarins as anti-inflammatory agents

scientific article (publication date: March 2003)

Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.

scientific article published on 17 June 2016

Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones

scientific article published on 20 April 2010

List of works by Manjunath Ghate

3D QSAR studies on substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonist.

3D QSAR-based design and liquid phase combinatorial synthesis of 1,2-disubstituted benzimidazole-5-carboxylic acid and 3-substituted-5H-benzimidazo[1,2-d][1,4]benzodiazepin-6(7H)-one derivatives as anti-mycobacterial agents

Benzopyran derivatives as cardio-selective ATP-sensitive potassium channel openers: a review

CoMFA and CoMSIA studies on aryl carboxylic acid amide derivatives as dihydroorotate dehydrogenase (DHODH) inhibitors

CoMFA and CoMSIA studies onC-aryl glucoside SGLT2 inhibitors as potential anti-diabetic agents ⬇️

Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors

Design, synthesis and docking studies of some novel (R)-2-(4'-chlorophenyl)-3-(4'-nitrophenyl)-1,2,3,5-tetrahydrobenzo[4,5] imidazo [1,2-c]pyrimidin-4-ol derivatives as antitubercular agents

Design, synthesis and pharmacological evaluation of novel substituted quinoline-2-carboxamide derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors and anticancer agents.

Design, synthesis, pharmacological evaluation and in silico ADMET prediction of novel substituted benzimidazole derivatives as angiotensin II-AT1 receptor antagonists based on predictive 3D QSAR models

Development of docking-based 3D QSAR models for the design of substituted quinoline derivatives as human dihydroorotate dehydrogenase (hDHODH) inhibitors

Homology modeling a fast tool for drug discovery: current perspectives

Homology modeling, binding site identification and docking study of human angiotensin II type I (Ang II-AT1) receptor

Identification of novel PfDHODH inhibitors as antimalarial agents via pharmacophore-based virtual screening followed by molecular docking and in vivo antimalarial activity

Ligand and structure-based approaches for the identification of SIRT1 activators.

Liquid-phase combinatorial library synthesis: recent advances and future perspectives.

Molecular modeling study for the design of novel acetyl-CoA carboxylase inhibitors using 3D QSAR, molecular docking and dynamic simulations.

Novel anticancer agents and targets: recent advances and future perspectives

Pharmacophore modeling, virtual screening, docking and in silico ADMET analysis of protein kinase B (PKB β) inhibitors ⬇️

Pharmacophore-based identification and in vitro validation of apoptosis inducers as anticancer agents

QSAR study on a series of aryl carboxylic acid amide derivatives as potential inhibitors of dihydroorotate dehydrogenase (DHODH)

Recent approaches to medicinal chemistry and therapeutic potential of dipeptidyl peptidase-4 (DPP-4) inhibitors.

Structure based lead optimization approach in discovery of selective DPP4 inhibitors

Structure-function relationship of substituted bromomethylcoumarins in nucleoside specificity of RNA alkylation

Substituted Benzimidazole Derivatives as Angiotensin II -AT1 Receptor Antagonist: A Review ⬇️

Synthesis and QSAR modeling of novel benzimidazolo thiazolidinones, thiazinones and 5-arylidene-2-imino thiazolidinones as antibacterial agents.

Synthesis of vanillin ethers from 4-(bromomethyl) coumarins as anti-inflammatory agents

Synthesis, anti-inflammatory, analgesic, 5-lipoxygenase (5-LOX) inhibition activities, and molecular docking study of 7-substituted coumarin derivatives.

Synthesis, characterization and antimicrobial studies of 2-(4-methoxy-phenyl)-5-methyl-4-(2-arylsulfanyl-ethyl)-2,4-dihydro-[1,2,4] triazolo-3-ones and their corresponding sulfones