List of works by Sharon Dent

A two-way street: LSD1 regulates chromatin boundary formation in S. pombe and Drosophila.

scientific article published on April 2007

AF9 YEATS domain links histone acetylation to DOT1L-mediated H3K79 methylation

scientific article

ATXN7L3 and ENY2 Coordinate Activity of Multiple H2B Deubiquitinases Important for Cellular Proliferation and Tumor Growth.

scientific article published on 27 April 2016

Chromatin "prepattern" and histone modifiers in a fate choice for liver and pancreas

scientific article

Chromatin 'resetting' during transcription elongation: a central role for methylated H3K36.

scientific article published in September 2012

Chromatin modifiers and remodellers: regulators of cellular differentiation

scientific article

Chromatin signaling to kinetochores: transregulation of Dam1 methylation by histone H2B ubiquitination

scientific article

Chromatin: receiver and quarterback for cellular signals

scientific article published on 31 January 2013

Complementary Roles of GCN5 and PCAF in Foxp3+ T-Regulatory Cells

scientific article published on 18 April 2019

DANPOS: dynamic analysis of nucleosome position and occupancy by sequencing

scientific article published on 28 November 2012

Developmental potential of Gcn5(-/-) embryonic stem cells in vivo and in vitro.

scientific article published in June 2007

Diencephalic Size Is Restricted by a Novel Interplay Between GCN5 Acetyltransferase Activity and Retinoic Acid Signaling.

scientific article published on 2 February 2017

Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia.

scientific article published on 11 March 2015

Expanded complexity of unstable repeat diseases.

scientific article published on 11 December 2012

Functions of SAGA in development and disease

scientific article

Gcn5 and PCAF negatively regulate interferon-β production through HAT-independent inhibition of TBK1.

scientific article

Gcn5 and PCAF regulate PPARγ and Prdm16 expression to facilitate brown adipogenesis

scientific article

Gcn5 and SAGA regulate shelterin protein turnover and telomere maintenance.

scientific article published in August 2009

Gcn5 loss-of-function accelerates cerebellar and retinal degeneration in a SCA7 mouse model.

scientific article

Histone H3K4 methylation regulates deactivation of the spindle assembly checkpoint through direct binding of Mad2

scientific article published on 19 May 2016

Histone modification profiling in breast cancer cell lines highlights commonalities and differences among subtypes

scientific article published on 20 February 2018

Histone modifying enzymes and cancer: going beyond histones.

scientific article

Histone-modifying enzymes: regulators of developmental decisions and drivers of human disease.

scientific article published on April 2012

Hyperexpansion of GAA repeats affects post-initiation steps of FXN transcription in Friedreich's ataxia

scientific article

Increased Susceptibility to Skin Carcinogenesis Associated with a Spontaneous Mouse Mutation in the Palmitoyl Transferase Zdhhc13 Gene

scientific article

KATapulting toward Pluripotency and Cancer

scientific article

KATs in cancer: functions and therapies

scientific article

Leucine-rich repeat containing 8A (LRRC8A)-dependent volume-regulated anion channel activity is dispensable for T-cell development and function.

scientific article published on 9 February 2017

Loss of Gcn5 acetyltransferase activity leads to neural tube closure defects and exencephaly in mouse embryos

scientific journal article

Low expression of ASH2L protein correlates with a favorable outcome in acute myeloid leukemia

scientific article published on 13 October 2016

N-Myc and GCN5 regulate significantly overlapping transcriptional programs in neural stem cells.

scientific article

No Spt6, no nucleosomes, no activator required

scientific article published on 01 February 2006

Physical and functional interaction of the yeast corepressor Tup1 with mRNA 5'-triphosphatase.

scientific article published on 13 March 2003

Proper expression of the Gcn5 histone acetyltransferase is required for neural tube closure in mouse embryos.

scientific article

REV7 is essential for DNA damage tolerance via two REV3L binding sites in mammalian DNA polymerase ζ

scientific article

Reactivation of the silenced and imprinted alleles of ARHI is associated with increased histone H3 acetylation and decreased histone H3 lysine 9 methylation

scientific article published in August 2003

Regulation of the osteoblast-specific transcription factor Osterix by NO66, a Jumonji family histone demethylase

scientific article

Resetting the histone code at CDKN2A in HNSCC by inhibition of DNA methylation

scientific article

Selecting and isolating colonies of human induced pluripotent stem cells reprogrammed from adult fibroblasts.

scientific article published on 20 February 2012

Sharon Dent: The unfolding SAGA of chromatin-modifying proteins

scientific article published in January 2016

Site-specific loss of acetylation upon phosphorylation of histone H3.

scientific article published on 30 May 2002

Stabilization of the promoter nucleosomes in nucleosome-free regions by the yeast Cyc8-Tup1 corepressor.

scientific article published on 2 November 2012

TGFβ-activated USP27X deubiquitinase regulates cell migration and chemoresistance via stabilization of Snail1

scientific article published on 19 October 2018

TRIM28 interacts with EZH2 and SWI/SNF to activate genes that promote mammosphere formation.

scientific article published on 9 January 2017

Targeting the SAGA and ATAC Transcriptional Coactivator Complexes in MYC-Driven Cancers

scientific article published on 24 February 2020

The H2BK123Rgument.

scientific article published in August 2009

The HP1alpha-CAF1-SetDB1-containing complex provides H3K9me1 for Suv39-mediated K9me3 in pericentric heterochromatin

scientific article

The Histone Acetyltransferase Gcn5 Positively Regulates T Cell Activation

scientific article

The Lysine Acetyltransferase GCN5 Is Required for iNKT Cell Development through EGR2 Acetylation

scientific article published in July 2017

The Set2 methyltransferase associates with Ssn6 yet Tup1-Ssn6 repression is independent of histone methylation

scientific article published on 28 November 2005

The role of chromatin modifiers in normal and malignant hematopoiesis

scientific article published on 02 January 2013

The role of deubiquitinating enzymes in chromatin regulation.

scientific article

Tousled-mediated activation of Aurora B kinase does not require Tousled kinase activity in vivo.

scientific article published on 10 March 2008

Transcriptional activation of Myc-induced genes by Gcn5 promotes B-cell lymphomagenesis

scientific article published on 09 November 2020

Transcriptional control: an activating role for arginine methylation.

scientific article

Tup1-Ssn6 interacts with multiple class I histone deacetylases in vivo.

scientific article

USP22 controls multiple signaling pathways that are essential for vasculature formation in the mouse placenta

scientific article published on 22 February 2019

USP22 regulates cell proliferation by deubiquitinating the transcriptional regulator FBP1

scientific article

USP44 Is an Integral Component of N-CoR that Contributes to Gene Repression by Deubiquitinating Histone H2B.

scientific article published on November 2016

Ubp8 and SAGA regulate Snf1 AMP kinase activity.

scientific article

Paulina is supported by:

About Paulina

Help