List of works - Pengyu Yang

"Click" synthesis of small-molecule inhibitors targeting caspases

scientific article

A small molecule promotes mitochondrial fusion in mammalian cells

scientific article published on 21 August 2012

A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli

scientific article published on 2 April 2013

Activity-based protein profiling: recent advances in probe development and applications

scientific article published on 04 February 2015

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities

scientific article

Chemical Modification and Organelle-Specific Localization of Orlistat-Like Natural-Product-Based Probes

article

Click-based synthesis and proteomic profiling of lipstatin analogues

scientific article

Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs

scientific article published on 13 December 2018

Design of Potent and Proteolytically Stable Oxyntomodulin Analogs

scientific article published on 4 January 2016

Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer

scientific article published on 04 May 2016

Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents

scientific article published on 4 April 2012

Dynamic monitoring of newly synthesized proteomes: up-regulation of myristoylated protein kinase A during butyric acid induced apoptosis.

scientific article published on 15 June 2011

Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery

scientific article published on 28 March 2016

Genetic incorporation of histidine derivatives using an engineered pyrrolysyl-tRNA synthetase.

scientific article published on 17 March 2014

High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening

scientific article published on 11 March 2009

Highly enantioselective iridium-catalyzed hydrogenation of heteroaromatic compounds, quinolines

scientific article

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

scientific article

Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication

scientific article published on April 2013

Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)

scientific article published on 15 July 2011

Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors

scientific article published on 6 September 2016

New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice

scientific article published on 03 April 2020

Palladium-catalyzed aminations of aryl halides with phosphine-functionalized imidazolium ligands

scientific article published on 14 December 2007

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent

scientific article

Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei

scientific article published on 28 November 2011

Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice

scientific article published on 21 December 2018

Recombinant thiopeptides containing noncanonical amino acids

scientific article published on 14 March 2016

Solid-Phase Synthesis of Azidomethylene Inhibitors Targeting Cysteine Proteases

scientific article published on 12 April 2008

Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate Induced Mouse Colitis Models

scientific article published on 23 March 2018

Synthesis and Highly Enantioselective Hydrogenation of Exocyclic Enamides: (Z)-3-Arylidene-4-acetyl-3,4-dihydro-2H- 1,4-benzoxazines

scientific article published on 01 March 2005

List of works by Pengyu Yang

"Click" synthesis of small-molecule inhibitors targeting caspases

A small molecule promotes mitochondrial fusion in mammalian cells

A tryptophanyl-tRNA synthetase/tRNA pair for unnatural amino acid mutagenesis in E. coli

Activity-based protein profiling: recent advances in probe development and applications

Activity-based proteome profiling of potential cellular targets of Orlistat--an FDA-approved drug with anti-tumor activities

Chemical Modification and Organelle-Specific Localization of Orlistat-Like Natural-Product-Based Probes

Click-based synthesis and proteomic profiling of lipstatin analogues

Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs

Design of Potent and Proteolytically Stable Oxyntomodulin Analogs

Design of Switchable Chimeric Antigen Receptor T Cells Targeting Breast Cancer

Design, synthesis and biological evaluation of potent azadipeptide nitrile inhibitors and activity-based probes as promising anti-Trypanosoma brucei agents

Dynamic monitoring of newly synthesized proteomes: up-regulation of myristoylated protein kinase A during butyric acid induced apoptosis.

Engineering a long-acting, potent GLP-1 analog for microstructure-based transdermal delivery

Genetic incorporation of histidine derivatives using an engineered pyrrolysyl-tRNA synthetase.

High-throughput synthesis of azide libraries suitable for direct "click" chemistry and in situ screening

Highly enantioselective iridium-catalyzed hydrogenation of heteroaromatic compounds, quinolines

Identification of a small molecule with activity against drug-resistant and persistent tuberculosis

Modulation of fatty acid synthase enzyme activity and expression during hepatitis C virus replication

Multicolor, One- and Two-Photon Imaging of Enzymatic Activities in Live Cells with Fluorescently Quenched Activity-Based Probes (qABPs)

Multifunctional Antibody Agonists Targeting Glucagon-like Peptide-1, Glucagon, and Glucose-Dependent Insulinotropic Polypeptide Receptors

New Generation Oxyntomodulin Peptides with Improved Pharmacokinetic Profiles Exhibit Weight Reducing and Anti-Steatotic Properties in Mice

Palladium-catalyzed aminations of aryl halides with phosphine-functionalized imidazolium ligands

Parasite-based screening and proteome profiling reveal orlistat, an FDA-approved drug, as a potential anti Trypanosoma brucei agent

Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei

Rapeseed Protein-Derived Antioxidant Peptide RAP Ameliorates Nonalcoholic Steatohepatitis and Related Metabolic Disorders in Mice

Recombinant thiopeptides containing noncanonical amino acids

Solid-Phase Synthesis of Azidomethylene Inhibitors Targeting Cysteine Proteases

Stapled, Long-Acting Glucagon-like Peptide 2 Analog with Efficacy in Dextran Sodium Sulfate Induced Mouse Colitis Models

Synthesis and Highly Enantioselective Hydrogenation of Exocyclic Enamides: (Z)-3-Arylidene-4-acetyl-3,4-dihydro-2H- 1,4-benzoxazines