List of works - Gabriele Giachin

A novel expression system for production of soluble prion proteins in E. coli

scientific article published on 10 January 2012

Characterization of prion protein function by focal neurite stimulation.

scientific article published on 2 September 2016

Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain

scientific article published on 03 January 2020

Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras

scientific article published on 30 August 2012

Dynamics of Human Mitochondrial Complex I Assembly: Implications for Neurodegenerative Diseases

scientific article

Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site

scientific article published on 27 July 2012

Epitope mapping of a PrP(Sc)-specific monoclonal antibody: identification of a novel C-terminally truncated prion fragment

scientific article published on 19 December 2010

In vitro aggregation assays for the characterization of α-synuclein prion-like properties.

scientific article published on January 2014

NMR Structure of the Human Prion Protein with the Pathological Q212P Mutation Reveals Unique Structural Features

scientific article

NMR structural studies of human cellular prion proteins

scientific article

Prion protein interaction with soil humic substances: environmental implications

scientific article (publication date: 2014)

Probing early misfolding events in prion protein mutants by NMR spectroscopy.

scientific article published on 07 August 2013

Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody

scientific article

Role of Prion Disease-Linked Mutations in the Intrinsically Disordered N-Terminal Domain of the Prion Protein

scientific article published on November 2013

Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins

scientific article published on 01 February 2020

Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism

scientific article

Structural determinants in prion protein folding and stability.

scientific article published on 2 October 2014

Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion

scientific article published on 09 December 2019

Structural facets of disease-linked human prion protein mutants: a molecular dynamic study

scientific article published in December 2010

Structural rearrangements at physiological pH: nuclear magnetic resonance insights from the V210I human prion protein mutant

scientific article

Synthetic prions and other human neurodegenerative proteinopathies.

scientific article

The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain.

scientific article

The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein

scientific article

The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion.

scientific article published on 20 October 2015

Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation

scientific article

Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease

scientific article published on 15 November 2019

List of works by Gabriele Giachin

A novel expression system for production of soluble prion proteins in E. coli

Characterization of prion protein function by focal neurite stimulation.

Deciphering Copper Coordination in the Mammalian Prion Protein Amyloidogenic Domain

Dominant-negative effects in prion diseases: insights from molecular dynamics simulations on mouse prion protein chimeras

Dynamics of Human Mitochondrial Complex I Assembly: Implications for Neurodegenerative Diseases

Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site

Epitope mapping of a PrP(Sc)-specific monoclonal antibody: identification of a novel C-terminally truncated prion fragment

In vitro aggregation assays for the characterization of α-synuclein prion-like properties.

NMR Structure of the Human Prion Protein with the Pathological Q212P Mutation Reveals Unique Structural Features

NMR structural studies of human cellular prion proteins

Prion protein interaction with soil humic substances: environmental implications

Probing early misfolding events in prion protein mutants by NMR spectroscopy.

Probing the N-terminal β-sheet conversion in the crystal structure of the human prion protein bound to a nanobody

Role of Prion Disease-Linked Mutations in the Intrinsically Disordered N-Terminal Domain of the Prion Protein

Structural basis for osmotic regulation of the DNA binding properties of H-NS proteins

Structural basis for the protective effect of the human prion protein carrying the dominant-negative E219K polymorphism

Structural determinants in prion protein folding and stability.

Structural evidence for the critical role of the prion protein hydrophobic region in forming an infectious prion

Structural facets of disease-linked human prion protein mutants: a molecular dynamic study

Structural rearrangements at physiological pH: nuclear magnetic resonance insights from the V210I human prion protein mutant

Synthetic prions and other human neurodegenerative proteinopathies.

The N Terminus of the Prion Protein Mediates Functional Interactions with the Neuronal Cell Adhesion Molecule (NCAM) Fibronectin Domain.

The mechanisms of humic substances self-assembly with biological molecules: The case study of the prion protein

The non-octarepeat copper binding site of the prion protein is a key regulator of prion conversion.

Toward the molecular basis of inherited prion diseases: NMR structure of the human prion protein with V210I mutation

Unique Structural Features of Mule Deer Prion Protein Provide Insights into Chronic Wasting Disease