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List of works by José Luis García-Giménez

A common SNP in the UNG gene decreases ovarian cancer risk in BRCA2 mutation carriers

article

A dinuclear copper(II) complex with adeninate bridge ligands and prominent DNA cleavage activity. Structural and spectroscopic characterization and magnetic properties.

scientific article published on 13 July 2007

A new mass spectrometry-based method for the quantification of histones in plasma from septic shock patients

scientific article published on 6 September 2017

A promising camptothecin derivative: Semisynthesis, antitumor activity and intestinal permeability.

scientific article

Acute telomerase components depletion triggers oxidative stress as an early event previous to telomeric shortening

scientific article published on 7 October 2017

Assessing the risk of cytomegalovirus DNAaemia in allogeneic stem cell transplant recipients by monitoring oxidative-stress markers in plasma.

scientific article published on 10 July 2017

Cellular Responses in Human Dental Pulp Stem Cells Treated with Three Endodontic Materials.

scientific article

Challenges in the analysis of epigenetic biomarkers in clinical samples.

scientific article published on 16 March 2017

Circular RNAs in Sepsis: Biogenesis, Function, and Clinical Significance

scientific article published on 25 June 2020

Circulating miR-323-3p is a biomarker for cardiomyopathy and an indicator of phenotypic variability in Friedreich's ataxia patients.

scientific article

Circulating miRNA expression analysis reveals new potential biomarkers for human cutaneous melanoma staging

scientific article published on 09 December 2019

Circulating miRNAs as diagnostic biomarkers for adolescent idiopathic scoliosis.

scientific article published on 8 February 2018

Cofilin dysregulation alters actin turnover in frataxin-deficient neurons

scientific article published on 23 March 2020

Corrigendum to "A Drosophila model of GDAP1 function reveals the involvement of insulin signalling in the mitochondria-dependent neuromuscular degeneration" [Biochim. Biophys. Acta 1863 (2017) 801-809]

article

Could thiazolidinediones increase the risk of heart failure in Friedreich's ataxia patients?

scientific article published on 05 April 2011

DNA binding, nuclease activity, DNA photocleavage and cytotoxic properties of Cu(II) complexes of N-substituted sulfonamides.

scientific article published on 11 January 2013

DNA cleavage reaction induced by dimeric copper(II) complexes of N-substituted thiazole sulfonamides

scientific article published on 28 November 2005

Decreased cell proliferation and higher oxidative stress in fibroblasts from Down Syndrome fetuses. Preliminary study.

scientific article published on 31 October 2013

Desmopresssin and hemodilution: implications in doping

scientific article published on 2 November 2009

Differential expression of PGC-1α and metabolic sensors suggest age-dependent induction of mitochondrial biogenesis in Friedreich ataxia fibroblasts

scientific article

Epigenetic IVD Tests for Personalized Precision Medicine in Cancer

scientific article published on 28 June 2019

Epigenetic Regulation in the Pathogenesis of Sjögren Syndrome and Rheumatoid Arthritis

scientific article published on 13 November 2019

Epigenetic biomarkers for human sepsis and septic shock: insights from immunosuppression

scientific article published on 12 May 2020

Epigenetic biomarkers: A new perspective in laboratory diagnostics.

scientific article published on June 2012

Epigenetic biomarkers: Current strategies and future challenges for their use in the clinical laboratory.

scientific article published on 11 December 2017

Erythropoietin and the heart: physiological effects and the therapeutic perspective

scientific article published on 18 December 2013

Expression of the genetic suppressor element 24.2 (GSE24.2) decreases DNA damage and oxidative stress in X-linked dyskeratosis congenita cells.

scientific article

Extracellular Histones Activate Endothelial NLRP3 Inflammasome and are Associated with a Severe Sepsis Phenotype

scientific article published in 2022

Extracellular histones activate autophagy and apoptosis via mTOR signaling in human endothelial cells

scientific article published on 11 July 2018

Extracellular histones disarrange vasoactive mediators release through a COX-NOS interaction in human endothelial cells.

scientific article

High stability of microRNAs in tissue samples of compromised quality

scientific article published on 03 October 2013

Histone H3 Glutathionylation in Proliferating Mammalian Cells Destabilizes Nucleosomal Structure ⬇️

scientific article published on May 21, 2013

Histone carbonylation occurs in proliferating cells.

scientific article published on 2 February 2012

Impact of periodontal treatment on the RANKL/OPG ratio in crevicular fluid

scientific article published on 27 January 2020

Increased oxidative stress and impaired antioxidant response in Lafora disease.

scientific article

Irisin: a new potential hormonal target for the treatment of obesity and type 2 diabetes.

scientific article published in September 2012

Lafora disease fibroblasts exemplify the molecular interdependence between thioredoxin 1 and the proteasome in mammalian cells.

scientific article published on 9 July 2013

Maintenance of glutathione levels and its importance in epigenetic regulation

scientific article

Nuclear glutathione

scientific article published on 13 October 2012

Oxidative Stress and Inflammation in COVID-19-Associated Sepsis: The Potential Role of Anti-Oxidant Therapy in Avoiding Disease Progression

scientific article published on 29 September 2020

Oxidative Stress and the Epigenetics of Cell Senescence: Insights from Progeroid Syndromes

scientific article published on 01 January 2018

Oxidative imbalance in low/intermediate-1-risk myelodysplastic syndrome patients: The influence of iron overload

scientific article

Oxidative nuclease activity of ferromagnetically coupled mu-hydroxo-mu-propionato copper(II) complexes [Cu3(L)2(mu-OH)2(mu-propionato)2] (L=N-(pyrid-2-ylmethyl)R-sulfonamidato, R=benzene, toluene, naphthalene).

scientific article published on 30 October 2008

Oxidative post-translational modifications in histones

scientific article published on 11 June 2019

Oxidative stress and mitochondrial dysfunction in Kindler syndrome

scientific article

Oxidative stress, a new hallmark in the pathophysiology of Lafora progressive myoclonus epilepsy.

scientific article

Oxygen in the neonatal period: Oxidative stress, oxygen load and epigenetic changes

scientific article published on 25 January 2020

Physical exercise and epigenetic modulation: elucidating intricate mechanisms

scientific article published on 01 April 2014

Reactive Glia-Derived Neuroinflammation: a Novel Hallmark in Lafora Progressive Myoclonus Epilepsy That Progresses with Age

scientific article published on 05 December 2019

Role of glutathione in the regulation of epigenetic mechanisms in disease

scientific article

Role of p16INK4a and BMI-1 in oxidative stress-induced premature senescence in human dental pulp stem cells.

scientific article

Small RNA-seq analysis of circulating miRNAs to identify phenotypic variability in Friedreich's ataxia patients

scientific article published on 6 March 2018

Thioredoxin and Glutaredoxin Systems as Potential Targets for the Development of New Treatments in Friedreich's Ataxia

scientific article published on 10 December 2020

Toward the development of metal-based synthetic nucleases: DNA binding and oxidative DNA cleavage of a mixed copper(II) complex with N-(9H-purin-6-yl)benzenesulfonamide and 1,10-phenantroline. Antitumor activity in human Caco-2 cells and Jurkat T ly

scientific article

miR-1226 detection in GCF as potential biomarker of chronic periodontitis: A pilot study.

scientific article published on 22 April 2018

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