List of works - Chris Jones

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.

scientific article published on 8 May 2009

A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications.

scientific article

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

scientific article published on 12 February 2009

Anti-platelet effect of aspirin is substantially reduced after administration of heparin during carotid endarterectomy

scientific article (publication date: September 2004)

Apheresis donors and platelet function: inherent platelet responsiveness influences platelet quality

scientific article published on 10 January 2008

Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy

scientific article (publication date: 30 March 2004)

Combined therapy with clopidogrel and aspirin significantly increases the bleeding time through a synergistic antiplatelet action

scientific article (publication date: June 2002)

Differential effects of the iodinated contrast agents Ioxaglate, Iohexol and Iodixanol on thrombus formation and fibrinolysis

scientific article published in January 2003

Discovery of novel GPVI receptor antagonists by structure-based repurposing

scientific article (publication date: 2014)

Effect of hypobaric hypoxia, simulating conditions during long-haul air travel, on coagulation, fibrinolysis, platelet function, and endothelial activation

scientific article

Endogenous inhibitory mechanisms and the regulation of platelet function.

scientific article

EphB2 regulates contact-dependent and contact-independent signaling to control platelet function

scientific article published on 4 November 2014

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

scientific article

Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers

scientific article

Height-reducing variants and selection for short stature in Sardinia

scientific article

Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi

scientific article

LXR as a novel antithrombotic target

scientific article published on 16 March 2011

Low molecular weight heparin significantly reduces embolisation after carotid endarterectomy--a randomised controlled trial

scientific article

Mandibular hypoplasia, deafness, progeroid features and lipodystrophy (MDPL) syndrome in the context of inherited lipodystrophies

scientific article

Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus

scientific article published in August 2007

PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways.

scientific article published on 20 October 2009

Pharmacological actions of nobiletin in the modulation of platelet function.

scientific article

Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3.

scientific article

Platelet endothelial cell adhesion molecule‐1 regulates collagen‐stimulated platelet function by modulating the association of phosphatidylinositol 3‐kinase with Grb‐2‐associated binding protein‐1 and linker for activation of T cells ⬇️

scientific article published on November 1, 2010

Platelet function and ageing

scientific article

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation

scientific article

Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe

scientific article (publication date: May 2014)

Population- and individual-specific regulatory variation in Sardinia.

scientific article published on 10 April 2017

Regulation of platelet biology by platelet endothelial cell adhesion molecule-1

scientific article published on 31 October 2011

Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function

scientific article published on 9 November 2015

Tangeretin regulates platelet function through inhibition of phosphoinositide 3-kinase and cyclic nucleotide signaling

scientific article published on 17 October 2013

The antithrombotic effect of dextran-40 in man is due to enhanced fibrinolysis in vivo.

scientific article

The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets

scientific article published on 2 December 2013

Therapeutic benefit of low-dose clopidogrel in patients undergoing carotid surgery is linked to variability in the platelet adenosine diphosphate response and patients' weight

scientific article (publication date: September 2007)

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

scientific article

Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial

scientific article published on 14 March 2013

List of works by Chris Jones

A functional genomics approach reveals novel quantitative trait loci associated with platelet signaling pathways.

A high-density immunoblotting methodology for quantification of total protein levels and phosphorylation modifications.

A novel variant on chromosome 7q22.3 associated with mean platelet volume, counts, and function

Anti-platelet effect of aspirin is substantially reduced after administration of heparin during carotid endarterectomy

Apheresis donors and platelet function: inherent platelet responsiveness influences platelet quality

Beneficial effects of clopidogrel combined with aspirin in reducing cerebral emboli in patients undergoing carotid endarterectomy

Combined therapy with clopidogrel and aspirin significantly increases the bleeding time through a synergistic antiplatelet action

Differential effects of the iodinated contrast agents Ioxaglate, Iohexol and Iodixanol on thrombus formation and fibrinolysis

Discovery of novel GPVI receptor antagonists by structure-based repurposing

Effect of hypobaric hypoxia, simulating conditions during long-haul air travel, on coagulation, fibrinolysis, platelet function, and endothelial activation

Endogenous inhibitory mechanisms and the regulation of platelet function.

EphB2 regulates contact-dependent and contact-independent signaling to control platelet function

Functional genomics in zebrafish permits rapid characterization of novel platelet membrane proteins

Genome sequencing elucidates Sardinian genetic architecture and augments association analyses for lipid and blood inflammatory markers

Height-reducing variants and selection for short stature in Sardinia

Integrin-linked kinase regulates the rate of platelet activation and is essential for the formation of stable thrombi

LXR as a novel antithrombotic target

Low molecular weight heparin significantly reduces embolisation after carotid endarterectomy--a randomised controlled trial

Mandibular hypoplasia, deafness, progeroid features and lipodystrophy (MDPL) syndrome in the context of inherited lipodystrophies

Mapping the platelet profile for functional genomic studies and demonstration of the effect size of the GP6 locus

PECAM-1 expression and activity negatively regulate multiple platelet signaling pathways.

Pharmacological actions of nobiletin in the modulation of platelet function.

Platelet endothelial cell adhesion molecule-1 inhibits platelet response to thrombin and von Willebrand factor by regulating the internalization of glycoprotein Ib via AKT/glycogen synthase kinase-3/dynamin and integrin αIIbβ3.

Platelet endothelial cell adhesion molecule‐1 regulates collagen‐stimulated platelet function by modulating the association of phosphatidylinositol 3‐kinase with Grb‐2‐associated binding protein‐1 and linker for activation of T cells ⬇️

Platelet function and ageing

Platelets release novel thiol isomerase enzymes which are recruited to the cell surface following activation

Population genomic analysis of ancient and modern genomes yields new insights into the genetic ancestry of the Tyrolean Iceman and the genetic structure of Europe

Population- and individual-specific regulatory variation in Sardinia.

Regulation of platelet biology by platelet endothelial cell adhesion molecule-1

Syncytiotrophoblast Extracellular Vesicles from Pre-Eclampsia Placentas Differentially Affect Platelet Function

Tangeretin regulates platelet function through inhibition of phosphoinositide 3-kinase and cyclic nucleotide signaling

The antithrombotic effect of dextran-40 in man is due to enhanced fibrinolysis in vivo.

The role of plasma membrane STIM1 and Ca(2+)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets

Therapeutic benefit of low-dose clopidogrel in patients undergoing carotid surgery is linked to variability in the platelet adenosine diphosphate response and patients' weight

Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function

Transient heparin-induced platelet activation linked to generation of platelet 12-lipoxygenase. Findings from a randomised controlled trial