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List of works by Wei Xiao

A single Mms2 "key" residue insertion into a Ubc13 pocket determines the interface specificity of a human Lys63 ubiquitin conjugation complex

scientific article (publication date: 6 May 2005)

A single amino acid substitution in MSH5 results in DNA alkylation tolerance

scientific article published in October 2003

A stable and sensitive genotoxic testing system based on DNA damage induced gene expression in Saccharomyces cerevisiae

scientific article published in August 2002

A transient duplication of the acetolactate synthase gene in a cell culture of Datura innoxia

scientific article published on 01 August 1987

Active Site Gate Dynamics Modulate the Catalytic Activity of the Ubiquitination Enzyme E2-25K.

scientific article

An NMR-based model of the ubiquitin-bound human ubiquitin conjugation complex Mms2.Ubc13. The structural basis for lysine 63 chain catalysis

scientific article (publication date: 11 April 2003)

An improved method for yeast 2 microns plasmid curing

scientific article published on 01 April 1990

Antisense RNA regulation of the ILV2 gene in yeast: a correction

scientific article published on 01 March 1994

Arabidopsis OTU1, a linkage-specific deubiquitinase, is required for endoplasmic reticulum-associated protein degradation

scientific article published on 10 October 2019

Arabidopsis UBC13 differentially regulates two programmed cell death pathways in responses to pathogen and low-temperature stress

scientific article published on 15 September 2018

Arabidopsis UEV1D promotes Lysine-63-linked polyubiquitination and is involved in DNA damage response

scientific article published on 4 January 2008

Arabidopsis cryptochrome 1 functions in nitrogen regulation of flowering

scientific article published on 20 June 2016

Arabidopsis thaliana UBC13: implication of error-free DNA damage tolerance and Lys63-linked polyubiquitylation in plants

scientific article

Arabidopsis thaliana Y-family DNA polymerase eta catalyses translesion synthesis and interacts functionally with PCNA2.

scientific article

Bcl10 activates the NF-kappaB pathway through ubiquitination of NEMO

scientific article

Biological significance of structural differences between two highly conserved Ubc variants

scientific article

CSN6, a subunit of the COP9 signalosome, is involved in early response to iron deficiency in Oryza sativa

scientific article published on 3 May 2016

Catalytic proficiency of ubiquitin conjugation enzymes: balancing pK(a) suppression, entropy, and electrostatics.

scientific article

Cdk1 interplays with Oct4 to repress differentiation of embryonic stem cells into trophectoderm

scientific journal article

Cdk1 is required for the self-renewal of mouse embryonic stem cells.

scientific article published on March 2011

Characterization of four rice UEV1 genes required for Lys63-linked polyubiquitination and distinct functions

scientific article

Cloning of industrial Saccharomyces 2-microns plasmid variants by in vivo site-specific recombination

scientific article published on 01 January 1990

Compromised DNA repair enhances sensitivity of the yeast RNR3-lacZ genotoxicity testing system

scientific article published on 12 June 2003

Constitutive fusion of ubiquitin to PCNA provides DNA damage tolerance independent of translesion polymerase activities

scientific article published on 12 April 2010

Construction and evaluation of two biosensors based on yeast transcriptional response to genotoxic chemicals

scientific article published on 23 January 2013

Creation of a hyperpermeable yeast strain to genotoxic agents through combined inactivation of PDR and CWP genes

scientific article published on 01 November 2009

Crystal structure of the human ubiquitin conjugating enzyme complex, hMms2-hUbc13

scientific article

DNA damage checkpoints are involved in postreplication repair.

scientific article published on 22 October 2006

DNA damage research in China

scientific article published on 08 November 2011

DNA damage-induced gene expression in Saccharomyces cerevisiae.

scientific article published on 26 June 2008

DNA mismatch repair mutants do not increase N-methyl-N'-nitro- N-nitrosoguanidine tolerance in O6-methylguanine DNA methyltransferase-deficient yeast cells

scientific article published on August 1, 1995

DNA postreplication repair and mutagenesis in Saccharomyces cerevisiae

scientific article

DNA postreplication repair modulated by ubiquitination and sumoylation.

scientific article

Deletion of the MAG1 DNA glycosylase gene suppresses alkylation-induced killing and mutagenesis in yeast cells lacking AP endonucleases

scientific article published in December 2001

Deletion of yeast CWP genes enhances cell permeability to genotoxic agents

scientific article published on 16 February 2008

Detection of Protein Posttranslational Modifications from Whole-Cell Extracts in Saccharomyces cerevisiae

scientific article published on 01 January 2014

Development of Th1 imprints to rBCG expressing a foreign protein: implications for vaccination against HIV-1 and diverse influenza strains

scientific article

Distinct regulation of Ubc13 functions by the two ubiquitin-conjugating enzyme variants Mms2 and Uev1A

scientific article

Distinct requirements for budding yeast Rev1 and Polη in translesion DNA synthesis across different types of DNA damage

scientific article published on 04 July 2020

Energetics and specificity of interactions within Ub.Uev.Ubc13 human ubiquitin conjugation complexes

scientific article published in July 2003

Error-free DNA-damage tolerance in Saccharomyces cerevisiae.

scientific article published on 16 February 2015

Eukaryotic DNA damage tolerance and translesion synthesis through covalent modifications of PCNA.

scientific article published on January 2008

Evidence for cis- and trans-acting element coevolution of the 2-microns circle genome in Saccharomyces cerevisiae

scientific article published on February 1991

Expression of Malus xiaojinensis IRT1 (MxIRT1) protein in transgenic yeast cells leads to degradation through autophagy in the presence of excessive iron.

scientific article

Expression of the human MGMT O6-methylguanine DNA methyltransferase gene in a yeast alkylation-sensitive mutant: its effects on both exogenous and endogenous DNA alkylation damage

scientific article published on 01 March 1995

FLP-FRT mediated intrachromosomal recombination on a tandemly duplicated YEp integrant at the ILV2 locus of chromosome XIII in Saccharomyces cerevisiae

scientific article published on 01 February 1989

Functional domains required for the Saccharomyces cerevisiae Mus81-Mms4 endonuclease complex formation and nuclear localization

scientific article published on 01 December 2003

Generation of an ilv bradytrophic phenocopy in yeast by antisense RNA.

scientific article

Genetic interactions between error-prone and error-free postreplication repair pathways in Saccharomyces cerevisiae

scientific article published on 01 September 1999

Identification and characterization of CRT10 as a novel regulator of Saccharomyces cerevisiae ribonucleotide reductase genes.

scientific article

Identification of a protein essential for a major pathway used by human cells to avoid UV- induced DNA damage

scientific article

Identification, chromosomal mapping and tissue-specific expression of hREV3 encoding a putative human DNA polymerase zeta.

scientific article

Inactivation of YAP1 enhances sensitivity of the yeast RNR3-lacZ genotoxicity testing system to a broad range of DNA-damaging agents

scientific article published on 30 December 2010

Involvement of budding yeast Rad5 in translesion DNA synthesis through physical interaction with Rev1

scientific article published on 21 March 2016

Involvement of homologous recombination repair after proton-induced DNA damage.

scientific article published on 10 February 2008

Involvement of two endonuclease III homologs in the base excision repair pathway for the processing of DNA alkylation damage in Saccharomyces cerevisiae

scientific article published in January 2004

Isolation of hMRE11B: failure to complement yeast mre11 defects due to species-specific protein interactions

scientific article

Isolation of yeast nucleic acids.

scientific article

Linear ubiquitin chain induces apoptosis and inhibits tumor growth

scientific article published on 28 November 2017

MMS1 protects against replication-dependent DNA damage in Saccharomyces cerevisiae

scientific article published on 29 November 2001

MMS2, encoding a ubiquitin-conjugating-enzyme-like protein, is a member of the yeast error-free postreplication repair pathway

scientific article

Mapping the chloroplast genome of triazine resistant canola.

scientific article published in February 1986

Mating type regulation of cellular tolerance to DNA damage is specific to the DNA post-replication repair and mutagenesis pathway.

scientific article

Mechanism for recognition of polyubiquitin chains: balancing affinity through interplay between multivalent binding and dynamics

scientific article published on 01 August 2010

Methionine reduces spontaneous and alkylation-induced mutagenesis in Saccharomyces cerevisiae cells deficient in O6-methylguanine-DNA methyltransferase.

scientific article published in November 1999

MicroRNA regulation of cancer stem cells in the pathogenesis of breast cancer

scientific article published on 07 January 2021

Mms4, a putative transcriptional (co)activator, protects Saccharomyces cerevisiae cells from endogenous and environmental DNA damage

scientific article

Molecular Cloning and Functional Characterization of Two Brachypodium distachyon UBC13 Genes Whose Products Promote K63-Linked Polyubiquitination

scientific article published in January 2015

Molecular basis of ataxia telangiectasia and related diseases

scientific article

Molecular cloning and functional characterization of two murine cDNAs which encode Ubc variants involved in DNA repair and mutagenesis

scientific journal article

Molecular cloning and genetic characterization of the Saccharomyces cerevisiae NGS1/MRE11 gene

article

Mutagenicity and toxicity of the DNA alkylation carcinogens 1,2-dimethylhydrazine and azoxymethane in Escherichia coli and Salmonella typhimurium

scientific article published in May 1996

Noncanonical E2 variant-independent function of UBC13 in promoting checkpoint protein assembly

scientific article published on 4 August 2008

Noncovalent interaction between ubiquitin and the human DNA repair protein Mms2 is required for Ubc13-mediated polyubiquitination

scientific article

Novel method for genomic promoter shuffling by using recyclable cassettes.

scientific article published on 6 September 2013

OsSEC24, a functional SEC24-like protein in rice, improves tolerance to iron deficiency and high pH by enhancing H(+) secretion mediated by PM-H(+)-ATPase

scientific article published on 8 January 2015

PCNA-Ub polyubiquitination inhibits cell proliferation and induces cell-cycle checkpoints

scientific article published on 18 October 2016

POPCORN functions in the auxin pathway to regulate embryonic body plan and meristem organization in Arabidopsis

scientific article

Pdr3 is required for DNA damage induction of MAG1 and DDI1 via a bi-directional promoter element

scientific article

Pol32 is required for Pol zeta-dependent translesion synthesis and prevents double-strand breaks at the replication fork

scientific article published on 28 June 2007

Polymorphism of 2-microns plasmids in industrial strains of Saccharomyces cerevisiae

scientific article published on 01 April 1993

Polymorphism within the nuclear and 2 micron genomes of Saccharomyces cerevisiae

scientific article

RAD5a and REV3 function in two alternative pathways of DNA-damage tolerance in Arabidopsis.

scientific article

REV3 is required for spontaneous but not methylation damage-induced mutagenesis of Saccharomyces cerevisiae cells lacking O6-methylguanine DNA methyltransferase

scientific article published on 01 December 1999

Rad6-Rad18 mediates a eukaryotic SOS response by ubiquitinating the 9-1-1 checkpoint clamp.

scientific article

Regulation of alternative replication bypass pathways at stalled replication forks and its effects on genome stability: a yeast model

scientific article published on November 2003

Regulation of nucleotide excision repair through ubiquitination

scientific article published on 10 October 2011

Rev7/Mad2B plays a critical role in the assembly of a functional mitotic spindle

scientific article published on December 2015

Roles of mouse UBC13 in DNA postreplication repair and Lys63-linked ubiquitination

scientific article (publication date: 20 February 2002)

Roles of sequential ubiquitination of PCNA in DNA-damage tolerance

scientific article published on 28 April 2011

Sequence diversity of yeast 2 microns RAF gene and its co-evolution with STB and REP1.

scientific article published in May 1991

Sequential assembly of translesion DNA polymerases at UV-induced DNA damage sites

scientific article

Sgs1 helicase is required for efficient PCNA monoubiquitination and translesion DNA synthesis in Saccharomyces cerevisiae

scientific article published on 16 September 2017

Similarities and differences between Arabidopsis PCNA1 and PCNA2 in complementing the yeast DNA damage tolerance defect.

scientific article

Spontaneous mutagenesis assay

scientific article published on 01 January 2014

Stochastic gate dynamics regulate the catalytic activity of ubiquitination enzymes

scientific article

Structural and functional conservation of error-free DNA postreplication repair in Schizosaccharomyces pombe

scientific article

Structural basis for non-covalent interaction between ubiquitin and the ubiquitin conjugating enzyme variant human MMS2

scientific article published on 01 February 2006

Structure and interactions of the ubiquitin-conjugating enzyme variant human Uev1a: implications for enzymatic synthesis of polyubiquitin chains

scientific article

Structure, interactions, and dynamics of the RING domain from human TRAF6

scientific article

Synergism between yeast nucleotide and base excision repair pathways in the protection against DNA methylation damage

scientific article published on 01 February 1998

The MAG1* 3-methyladenine DNA glycosylase gene is closely linked to the SPT15 TATA-binding TFIID gene on chromosome V-R in Saccharomyces cerevisiae.

scientific article

The Mre11-Rad50-Xrs2 complex is required for yeast DNA postreplication repair

scientific article

The Pol30-K196 residue plays a critical role in budding yeast DNA postreplication repair through interaction with Rad18.

scientific article

The Rad5 helicase activity is dispensable for error-free DNA post-replication repair

scientific article published on 13 March 2014

The TRAF6 RING finger domain mediates physical interaction with Ubc13.

scientific article published in May 2004

The construction of recombinant industrial yeasts free of bacterial sequences by directed gene replacement into a nonessential region of the genome

scientific article published on 01 March 1989

The first Sino-German Symposium on DNA Repair and Human Diseases

scientific article published on 2 February 2011

The repair of DNA methylation damage in Saccharomyces cerevisiae

scientific article published on 01 December 1996

The yeast Shu complex couples error-free post-replication repair to homologous recombination

scientific article

The yeast Shu complex utilizes homologous recombination machinery for error-free lesion bypass via physical interaction with a Rad51 paralogue

scientific article

TheSaccharomyces cerevisiae MGT1DNA repair methyltransferease gene: its promoter and entire coding sequence, regulation andin vivobiological functions

scientific article published on July 25, 1992

Three Brachypodium distachyon Uev1s Promote Ubc13-Mediated Lys63-Linked Polyubiquitination and Confer Different Functions

scientific article published on 18 October 2016

Transcriptomic profiling of chemical exposure reveals roles of Yap1 in protecting yeast cells from oxidative and other types of stresses.

scientific article published on 21 September 2015

Transpogenes: the transposition-like integration of short sequence DNA into the yeast 2 micron plasmid creates the STB locus and plasmid-size polymorphism

scientific article published in September 1994

Two Mms2 residues cooperatively interact with ubiquitin and are critical for Lys63 polyubiquitination in vitro and in vivo

scientific article published on 25 October 2007

Two duplicated genes DDI2 and DDI3 in budding yeast encode a cyanamide hydratase and are induced by cyanamide

scientific article

Two-stage transcriptional reprogramming in Saccharomyces cerevisiae for optimizing ethanol production from xylose

scientific article published on 21 May 2014

UBC13, an E2 enzyme for Lys63-linked ubiquitination, functions in root development by affecting auxin signaling and Aux/IAA protein stability.

scientific article published on 3 October 2014

UBP5 encodes a putative yeast ubiquitin-specific protease that is related to the human Tre-2 oncogene product

scientific article published in November 1994

Ube2s regulates Sox2 stability and mouse ES cell maintenance

scientific article published on 21 August 2015

Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation.

scientific article

Uev1A, a ubiquitin conjugating enzyme variant, inhibits stress-induced apoptosis through NF-kappaB activation

scientific article

Yeast chromatin remodeling complexes and their roles in transcription

scientific article published on 01 April 2020

Yeast survival and growth assays

scientific article published on 01 January 2014

Zebrafish Mms2 promotes K63-linked polyubiquitination and is involved in p53-mediated DNA-damage response

scientific article published on 3 November 2011

Zebrafish Ubc13 is required for Lys63-linked polyubiquitination and DNA damage tolerance.

scientific article published on 16 June 2010

hMMS2 serves a redundant role in human PCNA polyubiquitination

scientific article