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List of works by Corine Bertolotto

A Jurkat T cell variant resistant to death receptor-induced apoptosis. Correlation with heat shock protein (Hsp) 27 and 70 levels.

scientific article

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

scientific article

A germline oncogenic MITF mutation and tumor susceptibility.

scientific article published on 26 October 2013

A new KIT mutation (N505I) in acral melanoma confers constitutive signaling, favors tumorigenic properties, and is sensitive to imatinib.

scientific article

Advances in melanoma senescence and potential clinical application.

scientific article published on 11 January 2011

Autophagy plays a critical role in the degradation of active RHOA, the control of cell cytokinesis, and genomic stability.

scientific article

BMP-2 stimulates tyrosinase gene expression and melanogenesis in differentiated melanocytes

scientific article

BRCA1 is a new MITF target gene.

scientific article

CD271 is an imperfect marker for melanoma initiating cells.

scientific article

Cleavage of the Serum Response Factor during Death Receptor-induced Apoptosis Results in an Inhibition of the c-FOSPromoter Transcriptional Activity

scientific article published in Journal of Biological Chemistry

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance

scientific journal article

Compounds Triggering ER Stress Exert Anti-Melanoma Effects and Overcome BRAF Inhibitor Resistance.

scientific article

Constitutive ERK activity induces downregulation of tristetraprolin, a major protein controlling interleukin8/CXCL8 mRNA stability in melanoma cells.

scientific article published on 18 May 2011

Cyclic AMP promotes a peripheral distribution of melanosomes and stimulates melanophilin/Slac2-a and actin association

scientific article

Deciphering the Role of Oncogenic MITFE318K in Senescence Delay and Melanoma Progression

scientific article

Deregulated MITF sumoylation: A route to melanoma

scientific article published on 26 May 2017

Different cis-acting elements are involved in the regulation of TRP1 and TRP2 promoter activities by cyclic AMP: pivotal role of M boxes (GTCATGTGCT) and of microphthalmia

scientific article

Differential requirements for ERK1/2 and P38 MAPK activation by thrombin in T cells. Role of P59Fyn and PKCepsilon.

scientific article published in April 2001

Erratum: Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

scientific article published in Nature

Erratum: NF-kB2 induces senescence bypass in melanoma via a direct transcriptional activation of EZH2

scientific article published on 01 May 2016

Essential role of microphthalmia transcription factor for DNA replication, mitosis and genomic stability in melanoma.

scientific article published on 24 January 2011

FANCD2 functions as a critical factor downstream of MiTF to maintain the proliferation and survival of melanoma cells ⬇️

scientific article

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells

scientific article published on 18 January 2021

Fifteen-year quest for microphthalmia-associated transcription factor target genes

scientific article

Fitting MITF regulation of PDE4D3 into the skin pigmentation puzzle

scientific article published on 4 November 2010

Focus on cutaneous and uveal melanoma specificities.

scientific article published in April 2017

Functional role of MITF phosphorylation. In vivo veritas?

scientific article published on 19 August 2009

GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cells

scientific article

GLI2-mediated melanoma invasion and metastasis

scientific article

Glycogen Synthase Kinase 3β Is Activated by cAMP and Plays an Active Role in the Regulation of Melanogenesis

scientific article published in Journal of Biological Chemistry

Hypoxia and MITF control metastatic behaviour in mouse and human melanoma cells

scientific article published on 26 September 2011

Hypoxia-inducible factor 1{alpha} is a new target of microphthalmia-associated transcription factor (MITF) in melanoma cells

scientific article published on 27 June 2005

In B16 melanoma cells, the inhibition of melanogenesis by TPA results from PKC activation and diminution of microphthalmia binding to the M-box of the tyrosinase promoter

scientific article published on 01 April 1998

In vitro and in vivo anti-melanoma effects of ciglitazone.

scientific article

Increased CD271 expression by the NF-kB pathway promotes melanoma cell survival and drives acquired resistance to BRAF inhibitor vemurafenib

scientific article published on 27 October 2015

Inhibition of Rho is required for cAMP-induced melanoma cell differentiation.

scientific article published on June 1998

Inhibition of melanogenesis by the antidiabetic metformin

scientific article published on 22 April 2014

Inhibition of the Phosphatidylinositol 3-Kinase/p70S6-Kinase Pathway Induces B16 Melanoma Cell Differentiation

scientific article published in Journal of Biological Chemistry

Inhibition of the mitogen-activated protein kinase pathway triggers B16 melanoma cell differentiation.

scientific article published on April 1998

Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo

scientific article published on 16 May 2019

Involvement of FKHRL1 in melanoma cell survival and death.

scientific article

Involvement of microphthalmia in the inhibition of melanocyte lineage differentiation and of melanogenesis by agouti signal protein.

scientific article published in July 1998

Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells

scientific article published on 25 September 2018

MITF: a genetic key to melanoma and renal cell carcinoma?

scientific article

Melanoma models for the next generation of therapies

Melanoma: from melanocyte to genetic alterations and clinical options

scientific article

Metabolism under the spotlight in senescence.

scientific article

Metformin blocks melanoma invasion and metastasis development in AMPK/p53-dependent manner.

scientific article published on 5 June 2013

Metformin inhibits melanoma development through autophagy and apoptosis mechanisms.

scientific article

Microphthalmia associated transcription factor is a target of the phosphatidylinositol-3-kinase pathway.

scientific article published in October 2003

Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma

scientific article published on 28 November 2018

Microphthalmia-associated transcription factor controls the DNA damage response and a lineage-specific senescence program in melanomas.

scientific article published on 13 April 2010

Microphthalmia-associated transcription factor regulates RAB27A gene expression and controls melanosome transport

scientific article

Mitf is the key molecular switch between mouse or human melanoma initiating cells and their differentiated progeny.

scientific article published on 31 January 2011

Molecular phylogeny, species limits, and biogeography of the Brazilian endemic lizard genus Enyalius (Squamata: Leiosauridae): an example of the historical relationship between Atlantic Forests and Amazonia

scientific article published on 16 September 2014

NF-kB2 induces senescence bypass in melanoma via a direct transcriptional activation of EZH2.

scientific article published on 14 September 2015

NF1 loss induces senescence during human melanocyte differentiation in an iPSC-based model

scientific article published on 22 April 2015

Neural precursors express multiple chondroitin sulfate proteoglycans, including the lectican family

scientific article

Nicotinamide as a chemopreventive therapy of skin cancers. Too much of good thing?

scientific article published on 27 February 2019

Novel pathway of adipogenesis through cross-talk between adipose tissue macrophages, adipose stem cells and adipocytes: evidence of cell plasticity.

scientific article

PGJ2 restores RA sensitivity in melanoma cells by decreasing PRAME and EZH2.

scientific article

PI3K mediates protection against TRAIL-induced apoptosis in primary human melanocytes

scientific article published in October 2004

Pathways from senescence to melanoma: focus on MITF sumoylation.

scientific article published on 21 August 2017

Pivotal role of NAMPT in the switch of melanoma cells toward an invasive and drug-resistant phenotype.

scientific article published on 22 March 2018

REGULATION OF MELANOGENESIS BY THE AMINO-ACID TRANSPORTER SLC7A5

scientific article published on 30 March 2020

Regulatory and functional connection of microphthalmia-associated transcription factor and anti-metastatic pigment epithelium derived factor in melanoma

scientific article

SIRT1 promotes proliferation and inhibits the senescence-like phenotype in human melanoma cells

scientific article

SOX9 is a key player in ultraviolet B-induced melanocyte differentiation and pigmentation

scholarly article

Secretome from senescent melanoma engages the STAT3 pathway to favor reprogramming of naive melanoma towards a tumor-initiating cell phenotype

scientific article published on December 2013

Senescent cells develop a PARP-1 and nuclear factor-{kappa}B-associated secretome (PNAS)

scientific article

Signalling and chemosensitivity assays in melanoma: is mutated status a prerequisite for targeted therapy?

scientific article published on 01 December 2011

Targeting cancer cell metabolism: the combination of metformin and 2-deoxyglucose induces p53-dependent apoptosis in prostate cancer cells

scientific article published on 9 March 2010

Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas

scientific article published on 27 November 2018

The cleavage of microphthalmia-associated transcription factor, MITF, by caspases plays an essential role in melanocyte and melanoma cell apoptosis

scientific article published on September 2005

The complex relationship between MITF and the immune system: a Melanoma ImmunoTherapy (response) Factor?

scientific article published on 05 December 2020

Tumor-Derived Fibronectin Is Involved in Melanoma Cell Invasion and Regulated by V600E B-Raf Signaling Pathway

scientific article published on 07 September 2006

Uncovering and deciphering the pro-invasive role of HACE1 in melanoma cells.

scientific article published on 7 March 2018

Up-regulation of MET Expression by α-Melanocyte-stimulating Hormone and MITF Allows Hepatocyte Growth Factor to Protect Melanocytes and Melanoma Cells from Apoptosis

scientific article published in Journal of Biological Chemistry

ZEB1-mediated melanoma cell plasticity enhances resistance to MAPK inhibitors

scientific article published on 05 September 2016

[Key role of nicotinamide phosphoribosyltransferase (NAMPT) and NAD metabolism in the transition of melanoma cells to an invasive and drug-resistant phenotype]

scientific article published on 01 December 2018

{alpha}MSH and Cyclic AMP elevating agents control melanosome pH through a protein kinase A-independent mechanism.

scientific article published on 22 April 2009

β-caténine et N-ras

scientific article published on 01 February 2008

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