List of works - Roberto Ruller

A novel carbohydrate-binding module from sugar cane soil metagenome featuring unique structural and carbohydrate affinity properties

scientific article

A novel cold-adapted and glucose-tolerant GH1 β-glucosidase from Exiguobacterium antarcticum B7.

scientific article

A novel β-glucosidase isolated from the microbial metagenome of Lake Poraquê (Amazon, Brazil).

scientific article published on 15 February 2018

A practical teaching course in directed protein evolution using the green fluorescent protein as a model.

scientific article

A predominant role for hydrogen bonding in the stability of the homodimer of bothropstoxin-I, A lysine 49-phospholipase A2.

scientific article published in November 2005

Assembling a xylanase-lichenase chimera through all-atom molecular dynamics simulations

scientific article published on 28 February 2013

Bioethanol production by recycled Scheffersomyces stipitis in sequential batch fermentations with high cell density using xylose and glucose mixture.

scientific article

Characterization and mRNA expression analysis of PI31, an endogenous proteasome inhibitor from Schistosoma mansoni.

scientific article published on 3 August 2010

Characterization of a hexameric exo-acting GH51 α-l-arabinofuranosidase from the mesophilic Bacillus subtilis.

scientific article published in November 2013

Chemical denaturation of a homodimeric lysine-49 phospholipase A2: a stable dimer interface and a native monomeric intermediate

scientific article published in March 2003

Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of the catalytic domain of a hyperthermostable endo-1,4-beta-D-mannanase from Thermotoga petrophila RKU-1

scientific article

Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.

scientific article

Concommitant adaptation of a GH11 xylanase by directed evolution to create an alkali-tolerant/thermophilic enzyme

scientific article

Correlation of temperature induced conformation change with optimum catalytic activity in the recombinant G/11 xylanase A from Bacillus subtilis strain 168 (1A1)

scientific article published on 02 November 2005

Crystal structure and biochemical characterization of the recombinant ThBgl, a GH1 β-glucosidase overexpressed in Trichoderma harzianum under biomass degradation conditions.

scientific article

Crystallization and preliminary X-ray crystallographic studies of the mesophilic xylanase A from Bacillus subtilis 1A1.

scientific article published on 20 January 2005

Development and Biotechnological Application of a Novel Endoxylanase Family GH10 Identified from Sugarcane Soil Metagenome

scientific article

Development of a chimeric hemicellulase to enhance the xylose production and thermotolerance.

scientific article published on 5 December 2014

Development of hemicellulolytic enzyme mixtures for plant biomass deconstruction on target biotechnological applications.

scientific article published on 31 July 2014

Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168

scientific article

Draft genome sequence of Streptomyces sp. strain F1, a potential source for glycoside hydrolases isolated from Brazilian soil

scientific article published on 10 February 2017

Engineering increased thermostability in the GH-10 endo-1,4-β-xylanase from Thermoascus aurantiacus CBMAI 756.

scientific article published on 20 August 2016

Functional and biophysical characterization of a hyperthermostable GH51 α-l-arabinofuranosidase from Thermotoga petrophila ⬇️

scientific article published on September 25, 2010

Functional characterization and synergic action of fungal xylanase and arabinofuranosidase for production of xylooligosaccharides

scientific article published on 23 May 2012

GH53 Endo-Beta-1,4-Galactanase from a Newly Isolated Bacillus licheniformis CBMAI 1609 as an Enzymatic Cocktail Supplement for Biomass Saccharification

scientific article published on 15 February 2016

Increased biomass saccharification by supplementation of a commercial enzyme cocktail with endo-arabinanase from Bacillus licheniformis.

scientific article

Insights on calcium-independent phospholipid membrane damage by Lys49-PLA2 using tryptophan scanning mutagenesis of bothropstoxin-I from Bothrops jararacussu

scientific article published on 4 November 2007

Mechanistic Strategies for Catalysis Adopted by Evolutionary Distinct Family 43 Arabinanases

scientific article

Mode of operation and low-resolution structure of a multi-domain and hyperthermophilic endo-β-1,3-glucanase from Thermotoga petrophila

scientific article published on 23 February 2011

Molecular cloning, overexpression, purification and crystallographic analysis of a GH43 β-xylosidase from Bacillus licheniformis

scientific article published on 28 July 2015

Molecular mechanisms associated with xylan degradation by Xanthomonas plant pathogens

scientific article

Molecular modeling of the human eukaryotic translation initiation factor 5A (eIF5A) based on spectroscopic and computational analyses

scientific article

New Heterofunctional Supports Based on Glutaraldehyde-Activation: A Tool for Enzyme Immobilization at Neutral pH.

scientific article published on 29 June 2017

Oligomerization as a strategy for cold adaptation: Structure and dynamics of the GH1 β-glucosidase from Exiguobacterium antarcticum B7.

scientific article published on 31 March 2016

Purification and biochemical characterization of a novel alpha-glucosidase from Aspergillus niveus

scientific article published in November 2009

Structure and Function of a Novel Cellulase 5 from Sugarcane Soil Metagenome

scientific article

Structure of a novel thermostable GH51 α-L-arabinofuranosidase from Thermotoga petrophila RKU-1

scientific article

Structure-guided design combined with evolutionary diversity led to the discovery of the xylose-releasing exo-xylanase activity in the glycoside hydrolase family 43

scientific article published on 05 February 2019

Substrate cleavage pattern, biophysical characterization and low-resolution structure of a novel hyperthermostable arabinanase from Thermotoga petrophila.

scientific article

Tertiary structural changes of the alpha-hemolysin from Staphylococcus aureus on association with liposome membranes

scientific article published on 01 March 1998

The Penicillium echinulatum secretome on sugar cane bagasse

scientific article

Thermal-induced conformational changes in the product release area drive the enzymatic activity of xylanases 10B: Crystal structure, conformational stability and functional characterization of the xylanase 10B from Thermotoga petrophila RKU-1

scientific article

Topology of the substrate-binding site of a Lys49-phospholipase A2 influences Ca2+-independent membrane-damaging activity.

scientific article

Understanding the cellulolytic system of Trichoderma harzianum P49P11 and enhancing saccharification of pretreated sugarcane bagasse by supplementation with pectinase and α-L-arabinofuranosidase

scientific article published on 22 December 2012

Xylan-specific carbohydrate-binding module belonging to family 6 enhances the catalytic performance of a GH11 endo-xylanase

scientific article

List of works by Roberto Ruller

A novel carbohydrate-binding module from sugar cane soil metagenome featuring unique structural and carbohydrate affinity properties

A novel cold-adapted and glucose-tolerant GH1 β-glucosidase from Exiguobacterium antarcticum B7.

A novel β-glucosidase isolated from the microbial metagenome of Lake Poraquê (Amazon, Brazil).

A practical teaching course in directed protein evolution using the green fluorescent protein as a model.

A predominant role for hydrogen bonding in the stability of the homodimer of bothropstoxin-I, A lysine 49-phospholipase A2.

Assembling a xylanase-lichenase chimera through all-atom molecular dynamics simulations

Bioethanol production by recycled Scheffersomyces stipitis in sequential batch fermentations with high cell density using xylose and glucose mixture.

Characterization and mRNA expression analysis of PI31, an endogenous proteasome inhibitor from Schistosoma mansoni.

Characterization of a hexameric exo-acting GH51 α-l-arabinofuranosidase from the mesophilic Bacillus subtilis.

Chemical denaturation of a homodimeric lysine-49 phospholipase A2: a stable dimer interface and a native monomeric intermediate

Cloning, expression, purification, crystallization and preliminary X-ray diffraction studies of the catalytic domain of a hyperthermostable endo-1,4-beta-D-mannanase from Thermotoga petrophila RKU-1

Comparative genomics reveals high biological diversity and specific adaptations in the industrially and medically important fungal genus Aspergillus.

Concommitant adaptation of a GH11 xylanase by directed evolution to create an alkali-tolerant/thermophilic enzyme

Correlation of temperature induced conformation change with optimum catalytic activity in the recombinant G/11 xylanase A from Bacillus subtilis strain 168 (1A1)

Crystal structure and biochemical characterization of the recombinant ThBgl, a GH1 β-glucosidase overexpressed in Trichoderma harzianum under biomass degradation conditions.

Crystallization and preliminary X-ray crystallographic studies of the mesophilic xylanase A from Bacillus subtilis 1A1.

Development and Biotechnological Application of a Novel Endoxylanase Family GH10 Identified from Sugarcane Soil Metagenome

Development of a chimeric hemicellulase to enhance the xylose production and thermotolerance.

Development of hemicellulolytic enzyme mixtures for plant biomass deconstruction on target biotechnological applications.

Dissecting structure-function-stability relationships of a thermostable GH5-CBM3 cellulase from Bacillus subtilis 168

Draft genome sequence of Streptomyces sp. strain F1, a potential source for glycoside hydrolases isolated from Brazilian soil

Engineering increased thermostability in the GH-10 endo-1,4-β-xylanase from Thermoascus aurantiacus CBMAI 756.

Functional and biophysical characterization of a hyperthermostable GH51 α-l-arabinofuranosidase from Thermotoga petrophila ⬇️

Functional characterization and synergic action of fungal xylanase and arabinofuranosidase for production of xylooligosaccharides

GH53 Endo-Beta-1,4-Galactanase from a Newly Isolated Bacillus licheniformis CBMAI 1609 as an Enzymatic Cocktail Supplement for Biomass Saccharification

Increased biomass saccharification by supplementation of a commercial enzyme cocktail with endo-arabinanase from Bacillus licheniformis.

Insights on calcium-independent phospholipid membrane damage by Lys49-PLA2 using tryptophan scanning mutagenesis of bothropstoxin-I from Bothrops jararacussu

Mechanistic Strategies for Catalysis Adopted by Evolutionary Distinct Family 43 Arabinanases

Mode of operation and low-resolution structure of a multi-domain and hyperthermophilic endo-β-1,3-glucanase from Thermotoga petrophila

Molecular cloning, overexpression, purification and crystallographic analysis of a GH43 β-xylosidase from Bacillus licheniformis

Molecular mechanisms associated with xylan degradation by Xanthomonas plant pathogens

Molecular modeling of the human eukaryotic translation initiation factor 5A (eIF5A) based on spectroscopic and computational analyses

New Heterofunctional Supports Based on Glutaraldehyde-Activation: A Tool for Enzyme Immobilization at Neutral pH.

Oligomerization as a strategy for cold adaptation: Structure and dynamics of the GH1 β-glucosidase from Exiguobacterium antarcticum B7.

Purification and biochemical characterization of a novel alpha-glucosidase from Aspergillus niveus

Structure and Function of a Novel Cellulase 5 from Sugarcane Soil Metagenome

Structure of a novel thermostable GH51 α-L-arabinofuranosidase from Thermotoga petrophila RKU-1

Structure-guided design combined with evolutionary diversity led to the discovery of the xylose-releasing exo-xylanase activity in the glycoside hydrolase family 43

Substrate cleavage pattern, biophysical characterization and low-resolution structure of a novel hyperthermostable arabinanase from Thermotoga petrophila.

Tertiary structural changes of the alpha-hemolysin from Staphylococcus aureus on association with liposome membranes

The Penicillium echinulatum secretome on sugar cane bagasse

Thermal-induced conformational changes in the product release area drive the enzymatic activity of xylanases 10B: Crystal structure, conformational stability and functional characterization of the xylanase 10B from Thermotoga petrophila RKU-1

Topology of the substrate-binding site of a Lys49-phospholipase A2 influences Ca2+-independent membrane-damaging activity.

Understanding the cellulolytic system of Trichoderma harzianum P49P11 and enhancing saccharification of pretreated sugarcane bagasse by supplementation with pectinase and α-L-arabinofuranosidase

Xylan-specific carbohydrate-binding module belonging to family 6 enhances the catalytic performance of a GH11 endo-xylanase