List of works - Javier Sáez

Acetylcholinesterase activation in organotypic rat hippocampal slice cultures deprived of oxygen and glucose.

scientific article published in September 2003

Acetylcholinesterase level and molecular isoforms are altered in brain of Reelin Orleans mutant mice ⬇️

scientific article published on November 1, 2003

Acetylcholinesterase modulates presenilin-1 levels and γ-secretase activity.

scientific article published in January 2014

Acetylcholinesterase protein level is preserved in the Alzheimer's brain

scientific article

Alterations in the Balance of Amyloid-β Protein Precursor Species in the Cerebrospinal Fluid of Alzheimer's Disease Patients

scientific article

Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice.

scientific article published on 6 May 2011

Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition.

scientific article

Altered glycosylation of acetylcholinesterase in Creutzfeldt-Jakob disease.

scientific article published on 8 November 2005

Altered glycosylation of acetylcholinesterase in the Creutzfeldt-Jakob cerebrospinal fluid

scientific article published on 01 January 2006

Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in Alzheimer's disease.

scientific article

Altered levels of acetylcholinesterase in Alzheimer plasma

scientific article

Altered levels of cerebrospinal fluid reelin in frontotemporal dementia and Alzheimer's disease.

scientific article published on April 2003

Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease

scientific article published on 12 August 2020

ApoER2 processing by presenilin-1 modulates reelin expression

scientific article published on 16 December 2013

Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid.

scientific article published on 07 May 2008

Beta-amyloid controls altered Reelin expression and processing in Alzheimer's disease

scientific article

Biochemical properties of acetyl- and butyrylcholinesterase in human meningioma.

scientific article published in December 1996

Brain cholinergic impairment in liver failure.

scientific article published on 04 September 2008

Brain edema and inflammatory activation in bile duct ligated rats with diet-induced hyperammonemia: A model of hepatic encephalopathy in cirrhosis.

scientific article published in June 2006

C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease

scientific article

CSF Presenilin-1 complexes are increased in Alzheimer's disease

scientific article published on 06 August 2013

Caspase-3 activation by beta-amyloid and prion protein peptides is independent from their neurotoxic effect

scientific article published on 01 November 2000

Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease

scientific article published on 26 February 2007

Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels.

scientific article published on 28 May 2011

Changes in molecular isoform distribution of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloid beta-peptide.

scientific article published in June 2002

Characterization of Cerebrospinal Fluid BACE1 Species

scientific article published on 09 July 2019

Characterization of molecular forms of acetyl- and butyrylcholinesterase in human acoustic neurinomas

scientific article published on 01 October 1999

Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis

scientific article published on 27 December 2018

Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease.

scientific article published in May 2003

Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease.

scientific article published in September 1997

Identification of a 31-bp deletion in the RELN gene causing lissencephaly with cerebellar hypoplasia in sheep.

scientific article

Inhibition of neurite outgrowth from chick sympathetic neurons by cholinesterase inhibitors is not mediated by binding to cholinesterases

scientific article published on 01 May 1999

Inhibition of γ-Secretase Leads to an Increase in Presenilin-1.

scientific article published on 16 August 2017

Intraperitoneal administration of 340 kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats.

scientific article published on 12 April 2005

Levels of ADAM10 are reduced in Alzheimer's disease CSF

scientific article published on 25 July 2018

Molecular forms of acetyl- and butyrylcholinesterase in human glioma.

scientific article published in March 1996

Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease.

scientific article published in April 1999

Monomers and dimers of acetylcholinesterase in human meningioma are anchored to the membrane by glycosylphosphatidylinositol.

scientific article

Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation.

scientific article published on 25 February 2008

Presenilin-1 influences processing of the acetylcholinesterase membrane anchor PRiMA.

scientific article published on 6 February 2014

Quantification of the transcripts encoding different forms of AChE in various cell types: real-time PCR coupled with standards in revealing the copy number

scientific article published on 03 January 2014

Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update

scientific article published on August 2012

Reelin expression and glycosylation patterns are altered in Alzheimer's disease

scientific article

Ricinus communis agglutinin I reacting and non-reacting butyrylcholinesterase in human cerebrospinal fluid

scientific article published on September 28, 1992

Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression

scientific article published on 21 September 2020

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

scientific article published on 15 May 2015

Wheat germ agglutinin-binding glycoproteins are decreased in Alzheimer's disease cerebrospinal fluid.

scientific article published in December 2001

List of works by Javier Sáez

Acetylcholinesterase activation in organotypic rat hippocampal slice cultures deprived of oxygen and glucose.

Acetylcholinesterase level and molecular isoforms are altered in brain of Reelin Orleans mutant mice ⬇️

Acetylcholinesterase modulates presenilin-1 levels and γ-secretase activity.

Acetylcholinesterase protein level is preserved in the Alzheimer's brain

Alterations in the Balance of Amyloid-β Protein Precursor Species in the Cerebrospinal Fluid of Alzheimer's Disease Patients

Altered expression of brain acetylcholinesterase in FTDP-17 human tau transgenic mice.

Altered glycosylation of acetylcholinesterase in APP (SW) Tg2576 transgenic mice occurs prior to amyloid plaque deposition.

Altered glycosylation of acetylcholinesterase in Creutzfeldt-Jakob disease.

Altered glycosylation of acetylcholinesterase in the Creutzfeldt-Jakob cerebrospinal fluid

Altered glycosylation of cerebrospinal fluid butyrylcholinesterase in Alzheimer's disease.

Altered levels of acetylcholinesterase in Alzheimer plasma

Altered levels of cerebrospinal fluid reelin in frontotemporal dementia and Alzheimer's disease.

Amyloid precursor protein glycosylation is altered in the brain of patients with Alzheimer's disease

ApoER2 processing by presenilin-1 modulates reelin expression

Association between acetylcholinesterase and beta-amyloid peptide in Alzheimer's cerebrospinal fluid.

Beta-amyloid controls altered Reelin expression and processing in Alzheimer's disease

Biochemical properties of acetyl- and butyrylcholinesterase in human meningioma.

Brain cholinergic impairment in liver failure.

Brain edema and inflammatory activation in bile duct ligated rats with diet-induced hyperammonemia: A model of hepatic encephalopathy in cirrhosis.

C-terminal fragments of the amyloid precursor protein in cerebrospinal fluid as potential biomarkers for Alzheimer disease

CSF Presenilin-1 complexes are increased in Alzheimer's disease

Caspase-3 activation by beta-amyloid and prion protein peptides is independent from their neurotoxic effect

Cerebrospinal fluid acetylcholinesterase changes after treatment with donepezil in patients with Alzheimer's disease

Changes in acetylcholinesterase expression are associated with altered presenilin-1 levels.

Changes in molecular isoform distribution of acetylcholinesterase in rat cortex and cerebrospinal fluid after intracerebroventricular administration of amyloid beta-peptide.

Characterization of Cerebrospinal Fluid BACE1 Species

Characterization of molecular forms of acetyl- and butyrylcholinesterase in human acoustic neurinomas

Decreased circulating ErbB4 ectodomain fragments as a read-out of impaired signaling function in amyotrophic lateral sclerosis

Glycosylation of acetylcholinesterase and butyrylcholinesterase changes as a function of the duration of Alzheimer's disease.

Glycosylation of acetylcholinesterase as diagnostic marker for Alzheimer's disease.

Identification of a 31-bp deletion in the RELN gene causing lissencephaly with cerebellar hypoplasia in sheep.

Inhibition of neurite outgrowth from chick sympathetic neurons by cholinesterase inhibitors is not mediated by binding to cholinesterases

Inhibition of γ-Secretase Leads to an Increase in Presenilin-1.

Intraperitoneal administration of 340 kDa human plasma butyrylcholinesterase increases the level of the enzyme in the cerebrospinal fluid of rats.

Levels of ADAM10 are reduced in Alzheimer's disease CSF

Molecular forms of acetyl- and butyrylcholinesterase in human glioma.

Molecular isoform distribution and glycosylation of acetylcholinesterase are altered in brain and cerebrospinal fluid of patients with Alzheimer's disease.

Monomers and dimers of acetylcholinesterase in human meningioma are anchored to the membrane by glycosylphosphatidylinositol.

Presenilin 1 interacts with acetylcholinesterase and alters its enzymatic activity and glycosylation.

Presenilin-1 influences processing of the acetylcholinesterase membrane anchor PRiMA.

Quantification of the transcripts encoding different forms of AChE in various cell types: real-time PCR coupled with standards in revealing the copy number

Recommendations to standardize preanalytical confounding factors in Alzheimer's and Parkinson's disease cerebrospinal fluid biomarkers: an update

Reelin expression and glycosylation patterns are altered in Alzheimer's disease

Ricinus communis agglutinin I reacting and non-reacting butyrylcholinesterase in human cerebrospinal fluid

Tau phosphorylation by glycogen synthase kinase 3β modulates AChE expression

Validation of a quantitative cerebrospinal fluid alpha-synuclein assay in a European-wide interlaboratory study

Wheat germ agglutinin-binding glycoproteins are decreased in Alzheimer's disease cerebrospinal fluid.