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List of works by Christian Hackenberger

A supramolecular peptide synthesizer

scientific article published on 17 May 2013

A synthetic kiss of death: expressed protein ligation of a ubiquitin-peptide conjugate

scientific article published in July 2007

Acidic and basic deprotection strategies of borane-protected phosphinothioesters for the traceless Staudinger ligation

scientific article published on 9 April 2010

Alkyne phosphonites for sequential azide-azide couplings

scientific article published on 16 July 2013

An improved tripod amphiphile for membrane protein solubilization

scientific article published in May 2001

An improved tripod amphiphile for membrane protein solubilization.

scientific article published on December 2000

Analysis of Phosphorylation-dependent Protein Interactions of Adhesion and Degranulation Promoting Adaptor Protein (ADAP) Reveals Novel Interaction Partners Required for Chemokine-directed T cell Migration

scientific article

Bis(arylmethyl)-substituted unsymmetrical phosphites for the synthesis of lipidated peptides via Staudinger-phosphite reactions

scientific article published on 18 July 2016

Bis‐ethynylphosphonamidates as an Modular Conjugation Platform to Generate Multi‐Functional Protein‐ and Antibody‐Drug‐Conjugates

scientific article published in 2022

Broad substrate tolerance of tubulin tyrosine ligase enables one-step site-specific enzymatic protein labeling.

scientific article

Cell-permeable nanobodies for targeted immunolabelling and antigen manipulation in living cells.

scientific article published on 17 July 2017

Cellular uptake of large biomolecules enabled by cell-surface-reactive cell-penetrating peptide additives

scientific article published in 2021

Cell‐Permeable Nanobodies Allow Dual‐Color Super‐Resolution Microscopy in Untransfected Living Cells

scientific article published in 2021

Chemical Approaches to Investigate Labile Peptide and Protein Phosphorylation.

scientific article published on 19 July 2017

Chemical protein synthesis

scientific article published on 01 February 2014

Chemically Tailored Multivalent Virus Platforms: From Drug Delivery to Catalysis

scientific article published on 01 March 2010

Chemoselective Peptide Cyclization by Traceless Staudinger Ligation

scientific article published on 01 January 2008

Chemoselective Staudinger-phosphite reaction of azides for the phosphorylation of proteins.

scientific article published in January 2009

Chemoselective Staudinger-phosphite reaction of symmetrical glycosyl-phosphites with azido-peptides and polygycerols

scientific article published on 12 June 2012

Chemoselective bioconjugation of triazole phosphonites in aqueous media

scientific article published on 21 November 2014

Chemoselective labeling of engineered fucosylated glycoproteins

scientific article published in October 2007

Chemoselective ligation and modification strategies for peptides and proteins.

scientific article published on January 2008

Chemoselective synthesis and analysis of naturally occurring phosphorylated cysteine peptides

scientific article

Chemoselective triazole-phosphonamidate conjugates suitable for photorelease.

scientific article published on 8 January 2018

Compact hydrophilic electrophiles enable highly efficacious high DAR ADCs with excellent <i>in vivo</i> PK profile

scientific article published in 2023

Completion of proteomic data sets by Kd measurement using cell-free synthesis of site-specifically labeled proteins

scientific article

Controlled thioamide vs. amide formation in the thioacid–azide reaction under acidic aqueous conditions

scientific article published on 01 May 2014

Covalent attachment of cyclic TAT peptides to GFP results in protein delivery into live cells with immediate bioavailability

scientific article published on 17 December 2014

Cover Feature: Site‐Specific Antibody Fragment Conjugates for Reversible Staining in Fluorescence Microscopy (7/2021)

scientific article published in 2021

Current Status: Site-Specific Antibody Drug Conjugates

scientific article

Cysteine-Functional Polymers via Thiol-ene Conjugation

scientific article published on 21 January 2015

Cysteine-Selective Phosphonamidate Electrophiles for Modular Protein Bioconjugations.

scientific article

DFT‐Guided Discovery of Ethynyl‐Triazolyl‐Phosphinates as Modular Electrophiles for Chemoselective Cysteine Bioconjugation and Profiling

scientific article published in 2022

DFT‐basierte Entdeckung von Ethynyl‐Triazolyl‐Phosphinaten als modulare Elektrophile für die chemoselektive Cystein‐Biokonjugation und Profilierung

scientific article published in 2022

Design of S-Allylcysteine in Situ Production and Incorporation Based on a Novel Pyrrolysyl-tRNA Synthetase Variant

scientific article

Diethinylphosphinate für die Cystein‐selektive Proteinmarkierung und Disulfid‐Verbrückung

scientific article published in 2021

Diethynyl Phosphinates for Cysteine‐Selective Protein Labeling and Disulfide Rebridging

scientific article published in 2021

Direct access to site-specifically phosphorylated-lysine peptides from a solid-support

scientific article published on June 2015

Editorial overview: Synthetic biomolecules: Synthetic protein modifications-a giant leap towards understanding and generating biological functions

scientific article published on 21 September 2015

Efficient metabolic oligosaccharide engineering of glycoproteins by UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase (GNE) knock-down.

scientific article

Electron Transfer/Higher Energy Collisional Dissociation of Doubly Charged Peptide Ions: Identification of Labile Protein Phosphorylations

scientific article published on 20 May 2019

Enzymatically triggered amyloid formation: an approach for studying peptide aggregation

scientific article published on 30 March 2010

Ethynylphosphonamidates for the Rapid and Cysteine-Selective Generation of Efficacious Antibody-Drug Conjugates

scientific article published on 18 July 2019

Ethynylphosphonamidates for the Rapid and Cysteine‐Selective Generation of Efficacious Antibody–Drug Conjugates

scientific article published in 2019

Expression of N-terminal Cys-protein fragments using an intein refolding strategy.

scientific article

Fluorescent labelling in living cells.

scientific article published on 7 April 2017

Gas-Phase Rearrangement in Lysine Phosphorylated Peptides During Electron-Transfer Dissociation Tandem Mass Spectrometry

scientific article published on 29 June 2015

General synthesis of unsymmetrical norbornane scaffolds as inducers for hydrogen bond interactions in peptides

scientific article published in February 2004

Glycan-specific metabolic oligosaccharide engineering of C7-substituted sialic acids

scientific article published in June 2012

Improving glycopeptide synthesis: a convenient protocol for the preparation of beta-glycosylamines and the synthesis of glycopeptides.

scientific article published in April 2005

In-Cell Synthesis of Bioorthogonal Alkene Tag S-Allyl-Homocysteine and Its Coupling with Reprogrammed Translation ⬇️

scientific article published on 09 May 2019

Live-cell MRI with xenon hyper-CEST biosensors targeted to metabolically labeled cell-surface glycans

scientific article

Modern Ligation Methods to Access Natural and Modified Proteins

article published in 2018

Modern Peptide and Protein Chemistry: Reaching New Heights

scientific article published on 01 February 2020

More than add-on: chemoselective reactions for the synthesis of functional peptides and proteins.

scientific article published on 03 October 2014

Multicolor Caged dSTORM Resolves the Ultrastructure of Synaptic Vesicles in the Brain

scientific article published on 8 September 2015

Multivalente Peptid‐Nanopartikel‐Konjugate zur Hemmung des Influenzavirus

scientific article published in 2017

N-Hydroxysuccinimide-Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates

scientific article published on 07 January 2020

Nanobodies: Chemical Functionalization Strategies and Intracellular Applications.

scientific article

Native chemical ligation between asparagine and valine: application and limitations for the synthesis of tri-phosphorylated C-terminal tau.

scientific article

Perturbing the folding energy landscape of the bacterial immunity protein Im7 by site-specific N-linked glycosylation

scientific article

Phage capsid nanoparticles with defined ligand arrangement block influenza virus entry

scientific article published on 30 March 2020

Phosphoramidate-peptide synthesis by solution- and solid-phase Staudinger-phosphite reactions

scientific article published in October 2010

Protein Modification of Lysine with 2-(2-Styrylcyclopropyl)ethanal

scientific article published on 11 December 2019

Semi-synthesis of a tag-free O-GlcNAcylated tau protein by sequential chemoselective ligation.

scientific article

Semisynthese. Chemie mit den Molekülen der Natur

Side-chain cysteine-functionalized poly(2-oxazoline)s for multiple peptide conjugation by native chemical ligation.

scientific article

Site-Specifically Phosphorylated Lysine Peptides

scientific article published on 22 September 2014

Site-selective modification of proteins for the synthesis of structurally defined multivalent scaffolds

scientific article published on 09 November 2011

Site-specific PEGylation of proteins: recent developments

scientific article published on 3 November 2014

Site-specific functionalisation of proteins by a Staudinger-type reaction using unsymmetrical phosphites.

scientific article published on 11 March 2010

Site-specific modification of proteins by the staudinger-phosphite reaction.

scientific article

Small Molecules Targeting Human N-Acetylmannosamine Kinase

scientific article published on 27 March 2017

Stabilization of bacterially expressed erythropoietin by single site-specific introduction of short branched PEG chains at naturally occurring glycosylation sites

scientific article published on 18 January 2016

Stabilization of peptides for intracellular applications by phosphoramidate-linked polyethylene glycol chains

scientific article published on 22 August 2013

Staudinger Ligation and Reactions – From Bioorthogonal Labeling to Next‐Generation Biopharmaceuticals

scientific article published in 2022

Staudinger-phosphonite reactions for the chemoselective transformation of azido-containing peptides and proteins

scientific article published on 29 September 2011

Synthesis and evaluation of non-hydrolyzable phospho-lysine peptide mimics

scientific article published on 28 September 2020

Synthesis of N,N-disubstituted phosphoramidates via a Lewis acid-catalyzed phosphorimidate rearrangement

scientific article published on 18 April 2008

Synthesis of phosphonamidate peptides by Staudinger reactions of silylated phosphinic acids and esters

scientific article published on 7 September 2010

Synthetic and Spectroscopic Investigation ofN-Acylated Sulfoximines

scientific article published on 01 June 2004

Tag and release: strategies for the intracellular cleavage of protein conjugates

scientific article published on 31 May 2019

Tag-Free Semi-Synthesis of the Tau Protein.

scientific article published in January 2017

Targeted Subcellular Protein Delivery Using Cleavable Cyclic Cell-Penetrating Peptides

scientific article published on 14 January 2019

The Alzheimer's disease related tau protein as a new target for chemical protein engineering

scientific article published on 9 January 2012

The mechanism behind enhanced reactivity of unsaturated phosphorus(<scp>v</scp>) electrophiles towards thiols

scientific article published in 2021

The reduction of oxidized methionine residues in peptide thioesters with NH4I-Me2S.

scientific article published on 5 May 2006

The stability of pseudopeptides bearing sulfoximines as chiral backbone modifying element towards proteinase K

scientific article published on 01 October 2003

Traceless Staudinger acetylation of azides in aqueous buffers

scientific article

Traceless purification and desulfurization of tau protein ligation products

scientific article published on 17 November 2014

TuPPL: Tub-tag mediated C-terminal protein-protein-ligation using complementary click-chemistry handles

scientific article published on 01 April 2019

Tub-Tag Labeling; Chemoenzymatic Incorporation of Unnatural Amino Acids

scientific article published in January 2018

Turn Formation Initiated by a Bissulfoximine Motif:  Synthesis and Structural Investigation

scientific article published on 01 March 2002

Versatile and Efficient Site-Specific Protein Functionalization by Tubulin Tyrosine Ligase.

scientific article published on 25 September 2015

Vinylphosphonites for Staudinger-induced chemoselective peptide cyclization and functionalization

scientific article published on 16 May 2019

Werner Reutter: A Visionary Pioneer in Molecular Glycobiology.

scientific article published on 16 June 2017

Zellpermeable Nanobodys ermöglichen Zwei‐Farben‐Superauflösungsmikroskopie in lebenden, nicht transfizierten Zellen

scientific article published in 2021

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