List of works - Robin Shaw

3-OST-7 regulates BMP-dependent cardiac contraction

scientific article

A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia.

scientific article

A Surprising Noncanonical Role for Calcineurin in Pressure-Induced Cardiac Hypertrophy.

scientific article published in February 2018

A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders

scientific article

A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy

scientific article published on 01 April 2020

Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane.

scientific article

Acute vincristine pretreatment protects adult mouse cardiac myocytes from oxidative stress

scientific article published on 21 June 2007

An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression

scientific article published on 20 March 2020

Autoregulation of connexin43 gap junction formation by internally translated isoforms

scientific article published on 7 November 2013

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.

scientific article published on 2 December 2011

BIN1 localizes the L-type calcium channel to cardiac T-tubules

scientific article (publication date: February 2010)

CASAAV Technology to Examine Regulators of Heart Failure: Cause or Effect.

scientific article published in June 2017

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

scientific article

Cardiac T-Tubule Microanatomy and Function

scientific article

Cardiac conduction is required to preserve cardiac chamber morphology

scientific article

Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling

scientific article published in February 2009

Cardiac muscle is not a uniform syncytium.

scientific article published on June 2010

Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention

scientific article

Connexin 43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium.

scientific article published on June 2016

Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport

scientific article published on 7 November 2017

Cytoskeleton regulation of ion channels

scientific article

Desmosomal hotspots, microtubule delivery, and cardiac arrhythmogenesis.

scientific article published on October 2014

Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart

scientific article

Editorial commentary: Are cytokines ready for prime time? Insights from markers and trials

scientific article published on 20 March 2018

Editorial commentary: Extracellular vesicles in cardiovascular diagnosis and therapy

scientific article published on 14 November 2018

Electrophysiologic effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration

scientific article published in August 1997

Forward trafficking of ion channels: what the clinician needs to know.

scientific article published on 25 May 2010

GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs

scientific article published on 18 September 2017

Genetic and physiologic dissection of the vertebrate cardiac conduction system

scientific article

Intracellular trafficking pathways of Cx43 gap junction channels

scientific article published on 30 May 2017

Ion Channel Trafficking

Ion Channel Trafficking in the Heart

Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.

scientific article

L-type calcium channel targeting and local signalling in cardiac myocytes

scientific article

Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium

scientific article

Mammalian electrophysiology on a microfluidic platform

scientific article

Microfluidic application-specific integrated device for monitoring direct cell-cell communication via gap junctions between individual cell pairs

Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions

scientific article

Multilayered regulation of cardiac ion channels ⬇️

scientific article published on October 24, 2012

Na+ channel function, regulation, structure, trafficking and sequestration

scientific article

Performance of the REVEAL model in WHO Group 2 to 5 pulmonary hypertension: application beyond pulmonary arterial hypertension

scientific article

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy

scientific article

Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart.

scientific article published on 31 October 2016

Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5.

scientific article

Reduced sodium channels in human ARVC.

scientific article published on 22 December 2012

Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes

scientific journal article

Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction

scientific article published on 21 April 2008

The "tail" of Connexin43: An unexpected journey from alternative translation to trafficking.

scientific article published on 22 October 2015

The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles

scientific article published on 14 August 2017

The Vulnerable Window for Unidirectional Block in Cardiac Tissue:

scientific article published on 01 February 1995

The gap junction life cycle

scientific article published on 26 July 2011

Trafficking highways to the intercalated disc: new insights unlocking the specificity of connexin 43 localization.

scientific article published on February 2014

Validation of the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) pulmonary hypertension prediction model in a unique population and utility in the prediction of long-term survival.

scientific article

Visualizing cardiac ion channel trafficking pathways.

scientific article published on January 2012

Visualizing ion channel dynamics at the plasma membrane

scientific article published on 16 February 2008

List of works by Robin Shaw

3-OST-7 regulates BMP-dependent cardiac contraction

A 14-3-3 mode-1 binding motif initiates gap junction internalization during acute cardiac ischemia.

A Surprising Noncanonical Role for Calcineurin in Pressure-Induced Cardiac Hypertrophy.

A micropatterning approach for imaging dynamic Cx43 trafficking to cell-cell borders

A role for connexin-43 in Duchenne muscular dystrophy cardiomyopathy

Actin cytoskeleton rest stops regulate anterograde traffic of connexin 43 vesicles to the plasma membrane.

Acute vincristine pretreatment protects adult mouse cardiac myocytes from oxidative stress

An Alternatively Translated Connexin 43 Isoform, GJA1-11k, Localizes to the Nucleus and Can Inhibit Cell Cycle Progression

Autoregulation of connexin43 gap junction formation by internally translated isoforms

BIN1 is reduced and Cav1.2 trafficking is impaired in human failing cardiomyocytes.

BIN1 localizes the L-type calcium channel to cardiac T-tubules

CASAAV Technology to Examine Regulators of Heart Failure: Cause or Effect.

Cardiac BIN1 folds T-tubule membrane, controlling ion flux and limiting arrhythmia

Cardiac T-Tubule Microanatomy and Function

Cardiac conduction is required to preserve cardiac chamber morphology

Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling

Cardiac muscle is not a uniform syncytium.

Cardiomyocyte protein trafficking: Relevance to heart disease and opportunities for therapeutic intervention

Connexin 43 and CaV1.2 Ion Channel Trafficking in Healthy and Diseased Myocardium.

Cx43 Isoform GJA1-20k Promotes Microtubule Dependent Mitochondrial Transport

Cytoskeleton regulation of ion channels

Desmosomal hotspots, microtubule delivery, and cardiac arrhythmogenesis.

Dynasore protects mitochondria and improves cardiac lusitropy in Langendorff perfused mouse heart

Editorial commentary: Are cytokines ready for prime time? Insights from markers and trials

Editorial commentary: Extracellular vesicles in cardiovascular diagnosis and therapy

Electrophysiologic effects of acute myocardial ischemia: a theoretical study of altered cell excitability and action potential duration

Forward trafficking of ion channels: what the clinician needs to know.

GJA1-20k Arranges Actin to Guide Cx43 Delivery to Cardiac Intercalated Discs

Genetic and physiologic dissection of the vertebrate cardiac conduction system

Intracellular trafficking pathways of Cx43 gap junction channels

Ion Channel Trafficking

Ion Channel Trafficking in the Heart

Iroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.

L-type calcium channel targeting and local signalling in cardiac myocytes

Limited forward trafficking of connexin 43 reduces cell-cell coupling in stressed human and mouse myocardium

Mammalian electrophysiology on a microfluidic platform

Microfluidic application-specific integrated device for monitoring direct cell-cell communication via gap junctions between individual cell pairs

Microtubule plus-end-tracking proteins target gap junctions directly from the cell interior to adherens junctions

Multilayered regulation of cardiac ion channels ⬇️

Na+ channel function, regulation, structure, trafficking and sequestration

Performance of the REVEAL model in WHO Group 2 to 5 pulmonary hypertension: application beyond pulmonary arterial hypertension

Plasma BIN1 correlates with heart failure and predicts arrhythmia in patients with arrhythmogenic right ventricular cardiomyopathy

Rad-deletion Phenocopies Tonic Sympathetic Stimulation of the Heart.

Redox-sensitive sulfenic acid modification regulates surface expression of the cardiovascular voltage-gated potassium channel Kv1.5.

Reduced sodium channels in human ARVC.

Role for myosin-V motor proteins in the selective delivery of Kv channel isoforms to the membrane surface of cardiac myocytes

Stromal cell-derived factor-1alpha is cardioprotective after myocardial infarction

The "tail" of Connexin43: An unexpected journey from alternative translation to trafficking.

The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles

The Vulnerable Window for Unidirectional Block in Cardiac Tissue:

The gap junction life cycle

Trafficking highways to the intercalated disc: new insights unlocking the specificity of connexin 43 localization.

Validation of the Registry to Evaluate Early and Long-Term Pulmonary Arterial Hypertension Disease Management (REVEAL) pulmonary hypertension prediction model in a unique population and utility in the prediction of long-term survival.

Visualizing cardiac ion channel trafficking pathways.

Visualizing ion channel dynamics at the plasma membrane