List of works - Fredrik Svensson

5-Phenyl-1,3,4-oxadiazol-2(3H)-ones Are Potent Inhibitors of Notum Carboxylesterase Activity Identified by the Optimization of a Crystallographic Fragment Screening Hit

scientific article published on 30 October 2020

Changing the HTS Paradigm: AI-Driven Iterative Screening for Hit Finding

scientific article published on 18 August 2020

Conformal Regression for Quantitative Structure–Activity Relationship Modeling—Quantifying Prediction Uncertainty

scientific article published on 10 May 2018

Correction to "Using Predicted Bioactivity Profiles to Improve Predictive Modeling"

scientific article published on 24 November 2020

Decarboxylative palladium(II)-catalyzed synthesis of aryl amidines from aryl carboxylic acids: development and mechanistic investigation.

scientific article published on 28 August 2013

Design of a Potent, Selective, and Brain-Penetrant Inhibitor of Wnt-Deactivating Enzyme Notum by Optimization of a Crystallographic Fragment Hit

scientific article published on 10 May 2022

Fragment-Based Drug Discovery of Phosphodiesterase Inhibitors

scientific article published on 11 August 2017

GBM Drug Bank-a new resource for glioblastoma drug discovery and informatics research

scientific article published on 01 November 2018

Improving Screening Efficiency through Iterative Screening Using Docking and Conformal Prediction

scientific article published on 14 February 2017

Information-Derived Mechanistic Hypotheses for Structural Cardiotoxicity

scientific article published on 17 October 2018

Inhibition of Insulin-Regulated Aminopeptidase (IRAP) by Arylsulfonamides

scientific article published on 21 November 2014

LightGBM: An Effective and Scalable Algorithm for Prediction of Chemical Toxicity-Application to the Tox21 and Mutagenicity Data Sets

scientific article published on 09 October 2019

Maximizing gain in high-throughput screening using conformal prediction

scientific article published on 21 February 2018

Modelling compound cytotoxicity using conformal prediction and PubChem HTS data

Multitask Modeling with Confidence Using Matrix Factorization and Conformal Prediction

scientific article published on 05 April 2019

Palladium(II)-catalyzed desulfitative synthesis of aryl ketones from sodium arylsulfinates and nitriles: scope, limitations, and mechanistic studies

scientific article published on 31 October 2014

Systematic Analysis of Protein Targets Associated with Adverse Events of Drugs from Clinical Trials and Postmarketing Reports

scientific article published on 22 December 2020

Temperature measurements with two different IR sensors in a continuous-flow microwave heated system

scientific article published on 10 October 2013

Toward a benchmarking data set able to evaluate ligand- and structure-based virtual screening using public HTS data

scientific article

Understanding Conditional Associations between ToxCast in Vitro Readouts and the Hepatotoxicity of Compounds Using Rule-Based Methods

scientific article published on 20 September 2019

Virtual Screening for Transition State Analogue Inhibitors of IRAP Based on Quantum Mechanically Derived Reaction Coordinates

scientific article published on 7 August 2015

Virtual screening data fusion using both structure- and ligand-based methods