List of works - Alessio Squassina

A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics

scientific article

A case???control association study of the PDLIM5 gene and bipolar disorder in a Sardinian sample

article

A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric dis

scientific article published on 26 January 2020

Age at onset in bipolar disorder: Investigation of the role of TaqIA polymorphism of DRD2 gene in a Sardinian sample

article

Alzheimer's disease: case-control association study of polymorphisms in ACHE, CHAT, and BCHE genes in a Sardinian sample

scientific article published in October 2007

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

scientific article published on 31 May 2018

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report

scientific article published on 19 June 2013

Assessment of the pharmacogenomics educational environment in Southeast Europe.

scientific article published on 17 October 2014

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.

scientific article published on 9 November 2017

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

scientific article published on 16 March 2020

Association study in a Sardinian sample between bipolar disorder and the nuclear receptor REV-ERBalpha gene, a critical component of the circadian clock system

scientific article published in March 2009

Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case-control and family based study designs.

scientific article published on 24 July 2010

Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder

scientific article published in September 2008

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 01 September 2019

Bridging genomics research between developed and developing countries: the Genomic Medicine Alliance

C9ORF72repeat expansion and bipolar disorder - is there a link? No mutation detected in a Sardinian cohort of patients with bipolar disorder

scientific article published on 05 May 2014

Cellular models to study bipolar disorder: A systematic review

scientific article published on 28 May 2015

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

scientific article published on 7 June 2021

Convergent analysis of genome-wide genotyping and transcriptomic data suggests association of zinc finger genes with lithium response in bipolar disorder

article

Converging Evidence Points to BDNF as Biomarker of Depressive Symptoms in Schizophrenia-Spectrum Disorders

scientific article published in 2022

Differential effect of lithium on spermidine/spermine N1-acetyltransferase expression in suicidal behaviour

scientific article published on 17 June 2013

Ethical considerations for precision psychiatry: A roadmap for research and clinical practice

scientific article published in 2022

Evidence for association of anACCN1gene variant with response to lithium treatment in Sardinian patients with bipolar disorder

article

Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI

scientific article published on 21 November 2019

Exploring the Role of Gut Microbiota in Major Depressive Disorder and in Treatment Resistance to Antidepressants

scientific article published on 27 August 2020

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

scientific article published on 28 February 2019

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

scientific article published on 21 January 2016

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

scientific article

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

article

Golden Helix Pharmacogenomics Days: educational activities on pharmacogenomics and personalized medicine

scientific article published on 01 April 2012

HDAC3 role in medication consumption in medication overuse headache patients: a pilot study

scientific article

Increasing engagement in pharmacology and pharmacogenetics education using games and online resources: The PharmacoloGenius mobile app

scientific article published on 06 July 2020

Individualizing clozapine and risperidone treatment for schizophrenia patients

scientific article published on January 2014

Insulin-like Growth Factor 1 Differentially Affects Lithium Sensitivity of Lymphoblastoid Cell Lines from Lithium Responder and Non-responder Bipolar Disorder Patients

scientific article

Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients

scientific article published on 22 April 2013

Interacting genes in lithium prophylaxis: preliminary results of an exploratory analysis on the role of DGKH and NR1D1 gene polymorphisms in 199 Sardinian bipolar patients.

scientific article

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study

Investigation of endocannabinoid system genes suggests association between peroxisome proliferator activator receptor-α gene (PPARA) and schizophrenia

scientific article published on 21 August 2012

Investigation of the dopamine D5 receptor gene (DRD5) in adult attention deficit hyperactivity disorder

scientific article

Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders

scientific article

Leukocyte telomere length is reduced in patients with major depressive disorder

scientific article published on 01 November 2019

Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients

scientific article

Linkage of M5 muscarinic and alpha7-nicotinic receptor genes on 15q13 to schizophrenia

scientific article

Lithium Pharmacogenetics: Where Do We Stand?

scientific article published on 16 September 2016

Lithium-induced differential expression of SAT1 in suicide completers and controls is not correlated with polymorphisms in the promoter region of the gene

scientific article

Migraine and tumour necrosis factor gene polymorphism. An association study in a Sardinian sample

scientific article published in February 2009

Minimum information required for a DMET experiment reporting

scientific article published on 22 August 2016

Mixture regression analysis on age at onset in bipolar disorder patients: investigation of the role of serotonergic genes.

scientific article published on 8 May 2010

NRG1 and BDNF genes in schizophrenia: an association study in an Italian case-control sample

scientific article published on 12 January 2010

No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample

scientific article published on 31 July 2009

No association of endocannabinoid genes with bipolar disorder or lithium response in a Sardinian sample

scientific article published on 29 September 2013

Novel integrative genomic tool for interrogating lithium response in bipolar disorder.

scientific article published on 3 February 2015

Personalized medicine in bipolar disorder: how can we overcome the barriers to clinical translation?

scientific article published on 01 November 2013

Pharmacogenetics of lithium effects on glomerular function in bipolar disorder patients under chronic lithium treatment: a pilot study

scientific article published on 3 December 2016

Pharmacogenomics of bipolar disorder

scientific article published on April 2013

Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder

scientific article

Preliminary Transcriptome Analysis in Lymphoblasts from Cluster Headache and Bipolar Disorder Patients Implicates Dysregulation of Circadian and Serotonergic Genes.

scientific article published on 28 April 2015

RGS2 expression predicts amyloid-β sensitivity, MCI and Alzheimer's disease: genome-wide transcriptomic profiling and bioinformatics data mining.

scientific article

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice

scientific article

SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease.

scientific article

Selected rapporteur summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012.

scientific article

Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications

scientific article published on 12 September 2020

Telomere length in bipolar disorder and lithium response.

scientific article

Test Pricing and Reimbursement in Genomic Medicine: Towards a General Strategy

scientific article published on 28 September 2016

The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment

scientific article

The PDLIM5 gene and lithium prophylaxis: An association and gene expression analysis in Sardinian patients with bipolar disorder

article

The Role of Pharmacogenomics in Bipolar Disorder: Moving Towards Precision Medicine

scientific article published on 01 August 2018

The diacylglycerol kinase eta gene and bipolar disorder: a replication study in a Sardinian sample

article

Understanding the molecular mechanisms underlying mood stabilizer treatments in bipolar disorder: Potential involvement of epigenetics.

scientific article published on 22 June 2016

Whole Genome Expression Analyses of miRNAs and mRNAs Suggest the Involvement of miR-320a and miR-155-3p and their Targeted Genes in Lithium Response in Bipolar Disorder

scientific article published on 30 November 2019

List of works by Alessio Squassina

A European Spectrum of Pharmacogenomic Biomarkers: Implications for Clinical Pharmacogenomics

A case???control association study of the PDLIM5 gene and bipolar disorder in a Sardinian sample

A multidisciplinary approach to mental illness: do inflammation, telomere length and microbiota form a loop? A protocol for a cross-sectional study on the complex relationship between inflammation, telomere length, gut microbiota and psychiatric dis

Age at onset in bipolar disorder: Investigation of the role of TaqIA polymorphism of DRD2 gene in a Sardinian sample

Alzheimer's disease: case-control association study of polymorphisms in ACHE, CHAT, and BCHE genes in a Sardinian sample

Analysis of the Influence of microRNAs in Lithium Response in Bipolar Disorder.

Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: A Consortium on Lithium Genetics (ConLiGen) Report

Assessment of the pharmacogenomics educational environment in Southeast Europe.

Association of Polygenic Score for Schizophrenia and HLA Antigen and Inflammation Genes With Response to Lithium in Bipolar Affective Disorder: A Genome-Wide Association Study.

Association of polygenic score for major depression with response to lithium in patients with bipolar disorder

Association study in a Sardinian sample between bipolar disorder and the nuclear receptor REV-ERBalpha gene, a critical component of the circadian clock system

Association study of BDNF and DRD3 genes in schizophrenia diagnosis using matched case-control and family based study designs.

Association study of brain-derived neurotrophic factor (BDNF) and LIN-7 homolog (LIN-7) genes with adult attention-deficit/hyperactivity disorder

Author Correction: Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Bridging genomics research between developed and developing countries: the Genomic Medicine Alliance

C9ORF72repeat expansion and bipolar disorder - is there a link? No mutation detected in a Sardinian cohort of patients with bipolar disorder

Cellular models to study bipolar disorder: A systematic review

Common variants in Alzheimer's disease and risk stratification by polygenic risk scores

Convergent analysis of genome-wide genotyping and transcriptomic data suggests association of zinc finger genes with lithium response in bipolar disorder

Converging Evidence Points to BDNF as Biomarker of Depressive Symptoms in Schizophrenia-Spectrum Disorders

Differential effect of lithium on spermidine/spermine N1-acetyltransferase expression in suicidal behaviour

Ethical considerations for precision psychiatry: A roadmap for research and clinical practice

Evidence for association of anACCN1gene variant with response to lithium treatment in Sardinian patients with bipolar disorder

Evidence that genes involved in hedgehog signaling are associated with both bipolar disorder and high BMI

Exploring the Role of Gut Microbiota in Major Depressive Disorder and in Treatment Resistance to Antidepressants

Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing

Genetic variants associated with response to lithium treatment in bipolar disorder: a genome-wide association study

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Genome-wide association study of 40,000 individuals identifies two novel loci associated with bipolar disorder

Golden Helix Pharmacogenomics Days: educational activities on pharmacogenomics and personalized medicine

HDAC3 role in medication consumption in medication overuse headache patients: a pilot study

Increasing engagement in pharmacology and pharmacogenetics education using games and online resources: The PharmacoloGenius mobile app

Individualizing clozapine and risperidone treatment for schizophrenia patients

Insulin-like Growth Factor 1 Differentially Affects Lithium Sensitivity of Lymphoblastoid Cell Lines from Lithium Responder and Non-responder Bipolar Disorder Patients

Insulin-like growth factor 1 (IGF-1) expression is up-regulated in lymphoblastoid cell lines of lithium responsive bipolar disorder patients

Interacting genes in lithium prophylaxis: preliminary results of an exploratory analysis on the role of DGKH and NR1D1 gene polymorphisms in 199 Sardinian bipolar patients.

Investigating polygenic burden in age at disease onset in bipolar disorder: Findings from an international multicentric study

Investigation of endocannabinoid system genes suggests association between peroxisome proliferator activator receptor-α gene (PPARA) and schizophrenia

Investigation of the dopamine D5 receptor gene (DRD5) in adult attention deficit hyperactivity disorder

Investigation of the genetic interaction between BDNF and DRD3 genes in suicidical behaviour in psychiatric disorders

Leukocyte telomere length is reduced in patients with major depressive disorder

Leukocyte telomere length positively correlates with duration of lithium treatment in bipolar disorder patients

Linkage of M5 muscarinic and alpha7-nicotinic receptor genes on 15q13 to schizophrenia

Lithium Pharmacogenetics: Where Do We Stand?

Lithium-induced differential expression of SAT1 in suicide completers and controls is not correlated with polymorphisms in the promoter region of the gene

Migraine and tumour necrosis factor gene polymorphism. An association study in a Sardinian sample

Minimum information required for a DMET experiment reporting

Mixture regression analysis on age at onset in bipolar disorder patients: investigation of the role of serotonergic genes.

NRG1 and BDNF genes in schizophrenia: an association study in an Italian case-control sample

No association between lithium full responders and the DRD1, DRD2, DRD3, DAT1, 5-HTTLPR and HTR2A genes in a Sardinian sample

No association of endocannabinoid genes with bipolar disorder or lithium response in a Sardinian sample

Novel integrative genomic tool for interrogating lithium response in bipolar disorder.

Personalized medicine in bipolar disorder: how can we overcome the barriers to clinical translation?

Pharmacogenetics of lithium effects on glomerular function in bipolar disorder patients under chronic lithium treatment: a pilot study

Pharmacogenomics of bipolar disorder

Pharmacogenomics of mood stabilizers in the treatment of bipolar disorder

Preliminary Transcriptome Analysis in Lymphoblasts from Cluster Headache and Bipolar Disorder Patients Implicates Dysregulation of Circadian and Serotonergic Genes.

RGS2 expression predicts amyloid-β sensitivity, MCI and Alzheimer's disease: genome-wide transcriptomic profiling and bioinformatics data mining.

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

Realities and expectations of pharmacogenomics and personalized medicine: impact of translating genetic knowledge into clinical practice

SIRT1, miR-132 and miR-212 link human longevity to Alzheimer's Disease.

Selected rapporteur summaries from the XX World Congress of Psychiatric Genetics, Hamburg, Germany, October 14-18, 2012.

Telomere attrition and inflammatory load in severe psychiatric disorders and in response to psychotropic medications

Telomere length in bipolar disorder and lithium response.

Test Pricing and Reimbursement in Genomic Medicine: Towards a General Strategy

The International Consortium on Lithium Genetics (ConLiGen): an initiative by the NIMH and IGSLI to study the genetic basis of response to lithium treatment

The PDLIM5 gene and lithium prophylaxis: An association and gene expression analysis in Sardinian patients with bipolar disorder

The Role of Pharmacogenomics in Bipolar Disorder: Moving Towards Precision Medicine

The diacylglycerol kinase eta gene and bipolar disorder: a replication study in a Sardinian sample

Understanding the molecular mechanisms underlying mood stabilizer treatments in bipolar disorder: Potential involvement of epigenetics.

Whole Genome Expression Analyses of miRNAs and mRNAs Suggest the Involvement of miR-320a and miR-155-3p and their Targeted Genes in Lithium Response in Bipolar Disorder