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List of works by Julian Paton

14-3-3 proteins within the hypothalamic-neurohypophyseal system of the osmotically stressed rat: transcriptomic and proteomic studies.

scientific article

A cardiovascular role for fractalkine and its cognate receptor, CX3CR1, in the rat nucleus of the solitary tract.

scientific article published on 21 February 2012

A comparison of physiological and transcriptome responses to water deprivation and salt loading in the rat supraoptic nucleus

scientific article

A decerebrate, artificially-perfused in situ preparation of rat: utility for the study of autonomic and nociceptive processing

scientific article published on 23 February 2006

A fully implantable telemetry system for the chronic monitoring of brain tissue oxygen in freely moving rats

scientific article published in March 2012

A functional analysis of the influence of β3-adrenoceptors on the rat micturition cycle

scientific article published on 05 September 2013

A micro-optrode for simultaneous extracellular electrical and intracellular optical recording from neurons in an intact oscillatory neuronal network

scientific article

A spinal vasopressinergic mechanism mediates hyperosmolality-induced sympathoexcitation

scientific article published on 27 July 2006

A working heart-brainstem preparation of the rat for the study of reflex mediated autonomic influences on atrial arrhythmia development.

scientific article published in January 2013

A μ-opioid receptor agonist DAMGO induces rapid breathing in the arterially perfused in situ preparation of rat.

scientific article published on 13 April 2011

Abdominal expiratory activity in the rat brainstem-spinal cord in situ: patterns, origins and implications for respiratory rhythm generation

scientific article published on 2 June 2009

Activation of peripheral chemoreceptors causes positive inotropic effects in a working heart-brainstem preparation of the rat.

scientific article published in November 2007

Acute hydrocortisone administration reduces cardiovagal baroreflex sensitivity and heart rate variability in young men

scientific article published on 12 September 2018

Acute reductions in blood flow restricted to the dorsomedial medulla induce a pressor response in rats

scientific article published on 01 August 2011

Adaptive transcriptional dynamics of A2 neurons and central cardiovascular control pathways

scientific article

Amplified respiratory-sympathetic coupling in the spontaneously hypertensive rat: does it contribute to hypertension?

scientific article published on 08 December 2008

An efficient one-step site-directed deletion, insertion, single and multiple-site plasmid mutagenesis protocol

scientific article

An exploration of the control of micturition using a novel in situ arterially perfused rat preparation.

scientific article

Antagonism of orexin receptors significantly lowers blood pressure in spontaneously hypertensive rats.

scientific article

Are systolic function and ejection fraction interchangeable? New insights from cardiovascular magnetic resonance and in-vivo validation of mathematical models of LV function.

scientific article published on 3 February 2015

Area-specific differences in transmitter release in central catecholaminergic neurons of spontaneously hypertensive rats

scientific article published on 07 July 2008

Arteriovenous anastomosis: is this the way to control hypertension?

scientific article published on 07 April 2014

Astroglia are a possible cellular substrate of angiotensin(1-7) effects in the rostral ventrolateral medulla

scientific article

Automation of analysis of cardiovascular autonomic function from chronic measurements of arterial pressure in conscious rats

scientific article published on 20 October 2005

Autonomic mechanisms underpinning the stress response in borderline hypertensive rats.

scientific article

Autonomic-Immune-Vascular Interaction: An Emerging Concept for Neurogenic Hypertension

scientific article

Blockade of central vasopressin receptors reduces the cardiovascular response to acute stress in freely moving rats

scientific journal article

Brainstem hypoxia contributes to the development of hypertension in the spontaneously hypertensive rat.

scientific article

Brainstem respiratory networks: building blocks and microcircuits

scientific article

Brainstem: neural networks vital for life.

scientific article published on September 2009

Cardio-respiratory coupling depends on the pons

scientific article published on 29 July 2009

Carotid body overactivity induces respiratory neurone channelopathy contributing to neurogenic hypertension

scientific article

Carotid body removal for treatment of chronic systolic heart failure

scientific article

Cell- and region-specific miR30-based gene knock-down with temporal control in the rat brain

scientific article

Central regulation of heart rate and the appearance of respiratory sinus arrhythmia: new insights from mathematical modeling

scientific article

Chronic blockade of phosphatidylinositol 3-kinase in the nucleus tractus solitarii is prohypertensive in the spontaneously hypertensive rat

scientific journal article

Chronic depression of hypothalamic paraventricular neuronal activity produces sustained hypotension in hypertensive rats.

scientific article published on 18 October 2013

Clarity of the rhythmic brainstem

scientific article published on 20 March 2020

Comments on Point:Counterpoint: Respiratory sinus arrhythmia is due to a central mechanism vs. respiratory sinus arrhythmia is due to the baroreflex mechanism

scientific article published on 01 May 2009

Contributions of vascular inflammation in the brainstem for neurogenic hypertension

scientific article published on 12 May 2011

Control of cardiac contractility in the rat working heart-brainstem preparation

scientific article published on 28 August 2009

Correction of respiratory disorders in a mouse model of Rett syndrome.

scientific article

Counterpoint: Medullary pacemaker neurons are essential for gasping, but not eupnea, in mammals

scientific article published in August 2007

CrossTalk opposing view: Which technique for controlling resistant hypertension? Carotid chemoreceptor denervation/modulation

scientific article published on 01 September 2014

Deep brain stimulation for the treatment of resistant hypertension.

scientific article

Deep brain stimulation relieves refractory hypertension ⬇️

scientific article published on January 25, 2011

Defining inhibitory neurone function in respiratory circuits: opportunities with optogenetics?

scientific article

Dehydration-induced proteome changes in the rat hypothalamo-neurohypophyseal system.

scientific article

Detection of angiotensin II mediated nitric oxide release within the nucleus of the solitary tract using electron-paramagnetic resonance (EPR) spectroscopy

scientific article published on 3 April 2006

Differences in autonomic innervation to the vertebrobasilar arteries in spontaneously hypertensive and Wistar rats

scientific article published on 19 July 2018

Differences in transductional tropism of adenoviral and lentiviral vectors in the rat brainstem

scientific article published on 12 November 2004

Differential baroreflex control of sympathetic drive by angiotensin II in the nucleus tractus solitarii

scientific article published on 05 September 2007

Differential sensitivity of excitatory and inhibitory synaptic transmission to modulation by nitric oxide in rat nucleus tractus solitarii

scientific article published on 30 November 2006

Disinhibition of the cardiac limb of the arterial baroreflex in rat: a role for metabotropic glutamate receptors in the nucleus tractus solitarii

scientific article published on 29 June 2006

Dissociation between blood pressure and heart rate response to hypoxia after bilateral carotid body removal in men with systolic heart failure

article

Dominant role of aortic baroreceptors in the cardiac baroreflex of the rat in situ

scientific article published on 13 May 2008

Down-regulation of chemokine Ccl5 gene expression in the NTS of SHR may be pro-hypertensive.

scientific article

Dynamic changes in glottal resistance during exposure to severe hypoxia in neonatal rats in situ

scientific article

Effect of Sarizotan, a 5-HT1a and D2-like receptor agonist, on respiration in three mouse models of Rett syndrome

scientific article

Effect of baroreceptor stimulation on the respiratory pattern: insights into respiratory-sympathetic interactions

scientific article published on 15 September 2010

Elevated vertebrobasilar artery resistance in neonatal spontaneously hypertensive rats ⬇️

scientific article published on April 14, 2011

Endothelial NO synthase activity in nucleus tractus solitarii contributes to hypertension in spontaneously hypertensive rats

scientific article published on 28 August 2006

Enhancing respiratory sinus arrhythmia increases cardiac output in rats with left ventricular dysfunction

scientific article published on 09 December 2019

Essential role of RVL medullary neuronal activity in the long term maintenance of hypertension in conscious SHR.

scientific article published on 16 September 2014

Evaluating the physiological significance of respiratory sinus arrhythmia: looking beyond ventilation-perfusion efficiency

scientific article (publication date: 13 April 2012)

Evidence for cardiovascular autonomic dysfunction in neonates with coarctation of the aorta

scientific article

Evidence of specific inflammatory condition in nucleus tractus solitarii of spontaneously hypertensive rats

scientific article published on 18 November 2009

Excitatory convergence of periaqueductal gray and somatic afferents in the solitary tract nucleus: role for neurokinin 1 receptors

scientific article published on 02 September 2004

Exercise with angina and cramp?

scientific article published on 01 January 2011

Gene expression profiles of major cytokines in the nucleus tractus solitarii of the spontaneously hypertensive rat.

scientific article published on 13 August 2008

Harvey Cushing and the regulation of blood pressure in giraffe, rat and man: introducing 'Cushing's mechanism'.

scientific article published on 26 September 2008

Hierarchical recruitment of the sympathetic and parasympathetic limbs of the baroreflex in normotensive and spontaneously hypertensive rats

scientific article published on 14 December 2006

Hypertension and coarctation of the aorta: an inevitable consequence of developmental pathophysiology

scientific article published on 17 March 2011

Hypertension before and after posterior circulation infarction: analysis of data from the South London Stroke Register.

scientific article

Hypertension is critically dependent on the carotid body input in the spontaneously hypertensive rat.

scientific article

Hypothalamic paraventricular nucleus neuronal nitric oxide synthase activity is a major determinant of renal sympathetic discharge in conscious Wistar rats.

scientific article

IL-6 microinjected in the nucleus tractus solitarii attenuates cardiac baroreceptor reflex function in rats

scientific article published on 11 November 2009

Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior

scientific article

Improving the poor diagnostic accuracy of the ECG at detecting prognostically significant left ventricular hypertrophy in hypertensive patients.

scientific article

Increased sympathetic outflow in juvenile rats submitted to chronic intermittent hypoxia correlates with enhanced expiratory activity.

scientific article published in May 2008

Increasing brain serotonin corrects CO2 chemosensitivity in methyl‐CpG‐binding protein 2 (Mecp2)‐deficient mice ⬇️

scientific article published on November 23, 2012

Insights from cardiovascular magnetic resonance imaging supporting the selfish brain hypothesis of arterial hypertension

scientific article published on 3 February 2015

Intermittent hypoxia-induced sensitization of central chemoreceptors contributes to sympathetic nerve activity during late expiration in rats

scientific article

Intrinsic chemosensitivity of rostral ventrolateral medullary sympathetic premotor neurons in the in situ arterially perfused preparation of rats

scientific article

Introduction: the interplay between the autonomic and immune systems

scientific article published on 01 November 2012

Involvement of L-glutamate and ATP in the neurotransmission of the sympathoexcitatory component of the chemoreflex in the commissural nucleus tractus solitarii of awake rats and in the working heart-brainstem preparation.

scientific article published on 29 March 2007

Involvement of the purinergic system in central cardiovascular modulation at the level of the nucleus ambiguus of anaesthetized rats

scientific article published on 10 December 2010

Ionic currents and endogenous rhythm generation in the pre-Bötzinger complex: modelling and in vitro studies

scientific article published on 01 January 2004

Is neurogenic hypertension related to vascular inflammation of the brainstem?

scientific article published on 23 May 2008

Ischaemia-induced sympathoexcitation in spinalyzed rats

scientific article

Joint UK societies' 2014 consensus statement on renal denervation for resistant hypertension

scientific article

Junctional adhesion molecule-1 is upregulated in spontaneously hypertensive rats: evidence for a prohypertensive role within the brain stem

scientific journal article

Kidney-induced hypertension depends on superoxide signaling in the rostral ventrolateral medulla.

scientific article published on 6 July 2010

Late-expiratory activity: emergence and interactions with the respiratory CpG.

scientific article

Location and properties of respiratory neurones with putative intrinsic bursting properties in the rat in situ

scientific article published on 5 May 2009

Long-term intracellular recordings of respiratory neuronal activities in situ during eupnea, gasping and blockade of synaptic transmission

scientific article published in September 2005

Maintenance of eupnea and gasping following alterations in potassium ion concentration of perfusates of in situ rat preparation

scientific article published in March 2005

Maintenance of eupnea of in situ and in vivo rats following riluzole: a blocker of persistent sodium channels

scientific article published in July 2006

Mapping the cellular electrophysiology of rat sympathetic preganglionic neurones to their roles in cardiorespiratory reflex integration: a whole cell recording study in situ.

scientific article published on 24 March 2014

Mechanism of nitric oxide action on inhibitory GABAergic signaling within the nucleus tractus solitarii

scientific article published on 23 May 2006

Mechanisms of renal sympathetic activation in renovascular hypertension

scientific article

Modeling the ponto-medullary respiratory network.

scientific article

Modelling respiratory rhythmogenesis: focus on phase switching mechanisms.

scientific article published in January 2004

Modelling the vascular response to sympathetic postganglionic nerve activity

scientific article published on 16 February 2015

Modulation of respiratory sinus arrhythmia in rats with central pattern generator hardware

scientific article published on 28 September 2012

Multiple pontomedullary mechanisms of respiratory rhythmogenesis

scientific article

NOS antagonism using viral vectors as an experimental strategy: implications for in vivo studies of cardiovascular control and peripheral neuropathies.

scientific article published on January 2011

Neck muscle afferents influence oromotor and cardiorespiratory brainstem neural circuits ⬇️

scientific article published on 5 March 2014

Neural control of the lower urinary and gastrointestinal tracts: supraspinal CNS mechanisms.

scientific article published on January 2010

Neurogenic hypertension

scientific article published on 01 May 2010

Neurogenic hypertension and elevated vertebrobasilar arterial resistance: is there a causative link?

scientific article published on June 2012

Neurokininergic mechanism within the lateral crescent nucleus of the parabrachial complex participates in the heart-rate response to nociception.

scientific article published in February 2005

New insights into central control mechanisms of circulation. A Satellite Symposium of the 5th Congress of the International Society for Autonomic Neuroscience (ISAN 2007) Wakayama City (October 3rd 2007).

scientific article

Nitric oxide and respiratory rhythm in mammals: a new modulator of phase transition?

scientific article published on November 2007

Nitric oxide is fundamental to neurovascular coupling in humans

scientific article published on 12 August 2020

Normal range sympathetic tone in resistant hypertension associated with blood pressure increase following renal denervation in a pre-menopausal woman

scientific article published in May 2013

Normalization of autonomic function in children with coarctation of the aorta after surgical correction in infancy

scientific article published on 10 August 2009

Novel mechanism of brain soluble epoxide hydrolase-mediated blood pressure regulation in the spontaneously hypertensive rat.

scientific article published on 19 January 2005

On the presence and functional significance of sympathetic premotor neurons with collateralized spinal axons in the rat

scientific article published on 11 May 2019

Optical imaging of medullary ventral respiratory network during eupnea and gasping in situ

scientific article published in June 2006

Osmotic regulation of neuronal nitric oxide synthase expression in the rat amygdala: functional role for nitric oxide in adaptive responses?

scientific article published in February 2007

Over-expression of V1A receptors in PVN modulates autonomic cardiovascular control.

scientific article published on 31 October 2016

Overexpression of oxytocin receptors in the hypothalamic PVN increases baroreceptor reflex sensitivity and buffers BP variability in conscious rats

scientific article

Phenotyping patterns of left ventricular remodeling and hypertrophy in systemic hypertension by cardiac magnetic resonance (CMR).

scientific article published on 3 February 2015

Physiological and pathophysiological interactions between the respiratory central pattern generator and the sympathetic nervous system

scientific article published in January 2014

Pontomedullary transection attenuates central respiratory modulation of sympathetic discharge, heart rate and the baroreceptor reflex in the in situ rat preparation

scientific article published on 14 March 2008

Processing of central and reflex vagal drives by rat cardiac ganglion neurones: an intracellular analysis

scientific article published on 17 October 2011

Rebuttal from L. E. K. Ratcliffe, W. Pijacka, F. D. McBryde, A. P. Abdala, D. J. Moraes, P. A. Sobotka, E. C. Hart, K. Narkiewicz, A. K. Nightingale and J. F. R. Paton

scientific article published on 01 September 2014

Recent advances in the renin-angiotensin system: angiotensin-converting enzyme 2 and (pro)renin receptor

scientific article published on 01 May 2008

Reflexly evoked coactivation of cardiac vagal and sympathetic motor outflows: observations and functional implications.

scientific article published on December 2006

Relationship of aortic pulse wave velocity and baroreceptor reflex sensitivity to blood pressure control in patients with repaired coarctation of the aorta

scientific article published on 12 June 2011

Repetitive paired stimulation of nasotrigeminal and peripheral chemoreceptor afferents cause progressive potentiation of the diving bradycardia

scientific article

Reply from Aihua Li, Charles C. T. Hindmarch, Eugene E. Nattie and Julian F. R. Paton

scientific article

Respiratory rhythm entrainment by somatic afferent stimulation.

scientific article

Respiratory rhythm generation during gasping depends on persistent sodium current

scientific article published on 12 February 2006

Response to Role of the Carotid Body in Obesity-Related Sympathoactivation

scientific article published on 01 June 2013

Restraining influence of A2 neurons in chronic control of arterial pressure in spontaneously hypertensive rats

scientific article published on 29 June 2007

Revealing the role of the autonomic nervous system in the development and maintenance of Goldblatt hypertension in rats

scientific article published on 8 February 2014

Revelations about carotid body function through its pathological role in resistant hypertension

scientific article published on August 2013

Role of pontile mechanisms in the neurogenesis of eupnea

scientific article

Salt appetite is reduced by a single experience of drinking hypertonic saline in the adult rat.

scientific article

Selective up-regulation of JunD transcript and protein expression in vasopressinergic supraoptic nucleus neurones in water-deprived rats.

scientific article

Shift of leading pacemaker site during reflex vagal stimulation and altered electrical source-to-sink balance

scientific article published on 14 May 2019

Shift to an involvement of phosphatidylinositol 3-kinase in angiotensin II actions on nucleus tractus solitarii neurons of the spontaneously hypertensive rat.

scientific article published on 22 October 2009

Should we screen for intracranial aneurysms (IAs) in systemic hypertension at the time of cardiac magnetic resonance (CMR)?

scientific article

Signalling across the blood brain barrier by angiotensin II: novel implications for neurogenic hypertension.

scientific article published on 29 April 2008

Silicon central pattern generators for cardiac diseases.

scientific article published on 05 January 2015

Spatial and functional architecture of the mammalian brain stem respiratory network: a hierarchy of three oscillatory mechanisms

scientific article

Spatial organization and state-dependent mechanisms for respiratory rhythm and pattern generation

scientific article

Specific inflammatory condition in nucleus tractus solitarii of the SHR: novel insight for neurogenic hypertension?

scientific article published on 21 August 2008

Specific respiratory neuron types have increased excitability that drive presympathetic neurones in neurogenic hypertension

scientific article published on 31 March 2014

State-dependent control of the respiratory pattern and coupled oscillators

scientific article

Structural and functional architecture of respiratory networks in the mammalian brainstem

scientific article published on September 2009

Surgical approach for aortic coarctation influences arterial compliance and blood pressure control

scientific article published in August 2010

Switching control of sympathetic activity from forebrain to hindbrain in chronic dehydration

scientific article published on 27 June 2011

Sympathetic-mediated hypertension of awake juvenile rats submitted to chronic intermittent hypoxia is not linked to baroreflex dysfunction.

scientific article

Targeting specific neuronal populations using adeno- and lentiviral vectors: applications for imaging and studies of cell function.

scientific article

Temporal analysis of the spontaneous baroreceptor reflex during mild emotional stress in the rat

Temporal profile and mechanisms of the prompt sympathoexcitation following coronary ligation in Wistar rats

scientific article (publication date: 2014)

Temporal profile of arginine vasopressin release from the neurohypophysis in response to hypertonic saline and hypotension measured using a fluorescent fusion protein

scientific article published on 10 August 2011

The H50Q mutation induces a 10-fold decrease in the solubility of α-synuclein.

scientific article

The Hypothalamic‐Neurohypophyseal System: From Genome to Physiology ⬇️

scientific article published on April 1, 2012

The cardiovascular actions of fractalkine/CX3CL1 in the hypothalamic paraventricular nucleus are attenuated in rats with heart failure.

scientific article published on 13 September 2013

The carotid body as a putative therapeutic target for the treatment of neurogenic hypertension

scientific article published in January 2013

The challenge of real-time measurements of nitric oxide release in the brain.

scientific article

The effects of aging on biosynthetic processes in the rat hypothalamic osmoregulatory neuroendocrine system.

scientific article published on 31 January 2018

The sympathetic nervous system and blood pressure in humans: implications for hypertension ⬇️

scientific article published on 07 July 2011

The transcriptome of the medullary area postrema: the thirsty rat, the hungry rat and the hypertensive rat.

scientific article

The yin and yang of cardiac autonomic control: vago-sympathetic interactions revisited

scientific article

Transcription Factor CREB3L1 Regulates Endoplasmic Reticulum Stress Response Genes in the Osmotically Challenged Rat Hypothalamus

scientific article published on 27 April 2015

Transcription factor CREB3L1 regulates vasopressin gene expression in the rat hypothalamus.

scientific article published on March 2014

Translational examination of changes in baroreflex function after renal denervation in hypertensive rats and humans

scientific article published in July 2013

Uncoupling of rhythmic hypoglossal from phrenic activity in the rat.

scientific article published on 13 September 2004

Upregulation of junctional adhesion molecule-A is a putative prognostic marker of hypertension

scientific article

Variable role of carotid bodies in cardiovascular responses to exercise, hypoxia and hypercapnia in spontaneously hypertensive rats.

scientific article published on 5 January 2018

Vascular-brain signaling in hypertension: role of angiotensin II and nitric oxide.

scientific article published on June 2007

Viral vectors as tools for studies of central cardiovascular control.

scientific article published on February 2004

Viral vectors based on bidirectional cell-specific mammalian promoters and transcriptional amplification strategy for use in vitro and in vivo

scientific article published on 16 May 2008

Water deprivation increases the expression of neuronal nitric oxide synthase (nNOS) but not orexin-A in the lateral hypothalamic area of the rat.

scientific article published in September 2005

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