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List of works by Alexander Titz

A biophysical study with carbohydrate derivatives explains the molecular basis of monosaccharide selectivity of the Pseudomonas aeruginosa lectin LecB

scientific article

A rapid synthesis of low-nanomolar divalent LecA inhibitors in four linear steps from d-galactose pentaacetate

scientific article published on 06 July 2020

Amphiphilic cationic β(3R3)-peptides: membrane active peptidomimetics and their potential as antimicrobial agents.

scientific article

An efficient synthesis of 1,6-anhydro--acetylmuramic acid from -acetylglucosamine

Anti-biofilm Agents against Pseudomonas aeruginosa: A Structure-Activity Relationship Study of C-Glycosidic LecB Inhibitors

scientific article published on 11 October 2019

Bisecting Galactose as a Feature of N-Glycans of Wild-type and Mutant Caenorhabditis elegans

scientific article published on 22 May 2015

Caenorhabditis elegans N-glycan Core β-galactoside Confers Sensitivity towards Nematotoxic Fungal Galectin CGL2

scientific article

Chemical synthesis of tripeptide thioesters for the biotechnological incorporation into the myxobacterial secondary metabolite argyrin via mutasynthesis

scientific article published on 05 December 2019

Cinnamide Derivatives of d-Mannose as Inhibitors of the Bacterial Virulence Factor LecB from Pseudomonas aeruginosa

scientific article

Ciprofloxacin-loaded lipid-core nanocapsules as mucus penetrating drug delivery system intended for the treatment of bacterial infections in cystic fibrosis.

scientific article published on 9 May 2017

Complexation of copper(II)-Chelidamate: A multifrequency-pulsed electron paramagnetic resonance and electron nuclear double resonance analysis

scientific article published on 01 October 2006

Copper dipicolinates as peptidomimetic ligands for the Src SH2 domain

scientific article

Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging

scientific article published on 28 September 2017

Covalent Lectin Inhibition and Application in Bacterial Biofilm Imaging

Crystal Structures of Fungal Tectonin in Complex with O-Methylated Glycans Suggest Key Role in Innate Immune Defense

scientific article published in February 2018

Development and optimization of a competitive binding assay for the galactophilic low affinity lectin LecA from Pseudomonas aeruginosa.

scientific article published on 4 August 2016

Development of a competitive binding assay for the Burkholderia cenocepacia lectin BC2L-A and structure activity relationship of natural and synthetic inhibitors

article

Discovery of two classes of potent glycomimetic inhibitors of Pseudomonas aeruginosa LecB with distinct binding modes

scientific article

Electrochemical synthesis of dimerizing and nondimerizing orthoquinone monoketals

scientific article published in December 2004

Glycomimetic, orally bioavailable LecB inhibitors block biofilm formation of Pseudomonas aeruginosa.

scientific article published on 22 December 2017

Is adamantane a suitable substituent to pre-organize the acid orientation in E-selectin antagonists?

scientific article published on 22 August 2007

Methylated glycans as conserved targets of animal and fungal innate defense.

scientific article

Molecular basis for galactosylation of core fucose residues in invertebrates: identification of caenorhabditis elegans N-glycan core alpha1,6-fucoside beta1,4-galactosyltransferase GALT-1 as a member of a novel glycosyltransferase family

scientific article published on 26 October 2009

New approaches to control infections: anti-biofilm strategies against gram-negative bacteria.

scientific article published on January 2013

Novel Strategies for the Treatment of Pseudomonas aeruginosa Infections.

scientific article published on 23 January 2016

O-Alkylated heavy atom carbohydrate probes for protein X-ray crystallography: Studies towards the synthesis of methyl 2-O-methyl-L-selenofucopyranoside

scientific article published on 22 December 2016

Parasite Glycobiology: A Bittersweet Symphony

scientific article

Pathoblockers or antivirulence drugs as a new option for the treatment of bacterial infections

scientific article published on 11 October 2018

Photorhabdus luminescens lectin A (PllA): A new probe for detecting α-galactoside-terminating glycoconjugates

scientific article published on 28 September 2017

Photoswitchable Janus glycodendrimer micelles as multivalent inhibitors of LecA and LecB from Pseudomonas aeruginosa

Probing the carbohydrate recognition domain of E-selectin: the importance of the acid orientation in sLex mimetics.

scientific article

Synthesis of mannoheptose derivatives and their evaluation as inhibitors of the lectin LecB from the opportunistic pathogen Pseudomonas aeruginosa.

scientific article

The exo-β-N-acetylmuramidase NamZ from Bacillus subtilis is the founding member of a family of exo-lytic peptidoglycan hexosaminidases

scientific article published on 01 January 2021

The virulence factor LecB varies in clinical isolates: consequences for ligand binding and drug discovery

Towards the sustainable discovery and development of new antibiotics

scientific article published in 2021

Virtual Screening Against Carbohydrate-Binding Proteins: Evaluation and Application to Bacterial Burkholderia ambifaria Lectin

scientific article published on 04 September 2018

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