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List of works by Luke L. Lairson

A Small Molecule Inhibits Deregulated NRF2 Transcriptional Activity in Cancer

scientific article published on 13 August 2015

A cell type-selective apoptosis-inducing small molecule for the treatment of brain cancer

scientific article published on 07 March 2019

A regenerative approach to the treatment of multiple sclerosis

scientific article

A small molecule accelerates neuronal differentiation in the adult rat.

scientific article

Alternative donor substrates for inverting and retaining glycosyltransferases

scientific article published on 07 November 2006

An RNAi screen identifies TRRAP as a regulator of brain tumor-initiating cell differentiation

scientific article published in January 2010

Antitumor activity of a systemic STING-activating non-nucleotide cGAMP mimetic

scientific article published on 01 August 2020

Biochemical Characterization and Structure-Based Mutational Analysis Provide Insight into the Binding and Mechanism of Action of Novel Aspartate Aminotransferase Inhibitors

scientific article published on 12 November 2018

Chemical control of stem cell fate and developmental potential

scientific article published on January 2011

Electronic complementarity permits hindered butenolide heterodimerization and discovery of novel cGAS/STING pathway antagonists

scientific article published on 10 February 2020

Glycosyltransferases: structures, functions, and mechanisms

scientific article (publication date: 2008)

High-Throughput Screening Uncovers Novel Botulinum Neurotoxin Inhibitor Chemotypes

scientific article

High-throughput screening methodology for the directed evolution of glycosyltransferases

scientific article published in August 2006

Identification of a small molecule inhibitor of 3-phosphoglycerate dehydrogenase to target serine biosynthesis in cancers.

scientific article published in February 2016

Identification of clinically viable quinolinol inhibitors of botulinum neurotoxin A light chain

scientific article published on 15 January 2014

Intermediate trapping on a mutant retaining alpha-galactosyltransferase identifies an unexpected aspartate residue

scientific article

Mechanistic analogies amongst carbohydrate modifying enzymes

scientific article published on 27 September 2004

Mutational, structural, and kinetic evidence for a dissociative mechanism in the GDP-mannose mannosyl hydrolase reaction

scientific article published in June 2005

NMR spectroscopic characterization of the sialyltransferase CstII from Campylobacter jejuni: histidine 188 is the general base

scientific article

Pan-Src family kinase inhibitors replace Sox2 during the direct reprogramming of somatic cells

scientific article

Reprogramming of murine fibroblasts to induced pluripotent stem cells with chemical complementation of Klf4.

scientific article published on 15 May 2009

S-alk(en)yl-L-cysteine sulfoxides and relative pungency measurements of photosynthetic and nonphotosynthetic tissues of Allium porrum

scientific article published on 6 September 2007

Small molecule-based approaches to adult stem cell therapies

scientific article

Small molecule-mediated inhibition of myofibroblast transdifferentiation for the treatment of fibrosis

scientific article published on 17 April 2017

Smartphone Analytics: Mobilizing the Lab into the Cloud for Omic-Scale Analyses

scientific article

Structural analysis of the alpha-2,3-sialyltransferase Cst-I from Campylobacter jejuni in apo and substrate-analogue bound forms

scientific article

Structural analysis of the sialyltransferase CstII from Campylobacter jejuni in complex with a substrate analog

scientific article

Structural and Kinetic Analysis of Substrate Binding to the Sialyltransferase Cst-II from Campylobacter jejuni

scientific article

Systems biology guided by XCMS Online metabolomics

scientific article published on April 2017

Using substrate engineering to harness enzymatic promiscuity and expand biological catalysis

scientific article published on 22 October 2006

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