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List of works by Neil Mabbott

Ablation of the cellular prion protein, PrPC, specifically on follicular dendritic cells has no effect on their maturation or function

scholarly article by Laura McCulloch et al published March 2013 in Immunology

Activated Peyer′s patch B cells sample antigen directly from M cells in the subepithelial dome

scientific article published on 03 June 2019

African trypanosome infections in mice that lack the interferon-gamma receptor gene: nitric oxide-dependent and -independent suppression of T-cell proliferative responses and the development of anaemia.

scientific article published in August 1998

Ageing adversely affects the migration and function of marginal zone B cells.

scientific article

Aging and the mucosal immune system in the intestine

scientific article published on 05 April 2014

An endogenous nanomineral chaperones luminal antigen and peptidoglycan to intestinal immune cells ⬇️

scientific article published on 9 March 2015

An expression atlas of human primary cells: inference of gene function from coexpression networks

scientific article

Antigen-presenting ILC3 regulate T cell-dependent IgA responses to colonic mucosal bacteria

article

Assessing the involvement of migratory dendritic cells in the transfer of the scrapie agent from the immune to peripheral nervous systems

scientific article published on 11 June 2007

B cell-specific S1PR1 deficiency blocks prion dissemination between secondary lymphoid organs

scientific article

Bovine cryptosporidiosis: impact, host-parasite interaction and control strategies.

scientific article published on 11 August 2017

CSF-1 receptor-mediated differentiation of a new type of monocytic cell with B cell-stimulating activity: its selective dependence on IL-34.

scientific article published on 19 September 2013

Can DCs be distinguished from macrophages by molecular signatures?

scientific article published on 01 March 2013

Characterisation of a novel Fc conjugate of macrophage colony-stimulating factor

scientific article published on 25 June 2014

Clusterin expression in follicular dendritic cells associated with prion protein accumulation

scientific article published on 01 August 2006

Complement component C5 is not involved in scrapie pathogenesis

scientific article published on 01 January 2004

Defining the anatomical localisation of subsets of the murine mononuclear phagocyte system using integrin alpha X (Itgax, CD11c) and colony stimulating factor 1 receptor (Csf1r, CD115) expression fails to discriminate dendritic cells from macrophage

scientific article published on 17 August 2011

Deletion of a Csf1r enhancer selectively impacts CSF1R expression and development of tissue macrophage populations

scientific article published on 19 July 2019

Determining the role of mononuclear phagocytes in prion neuroinvasion from the skin

scientific article

Development of in vitro enteroids derived from bovine small intestinal crypts.

scientific article published on 3 July 2018

Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice

article published in 2019

Effects of host-derived chemokines on the motility and viability of Trypanosoma brucei

scientific article published on 27 December 2018

Evidence of subclinical prion disease in aged mice following exposure to bovine spongiform encephalopathy

scientific article published on 15 October 2013

Expression of mesenchyme-specific gene signatures by follicular dendritic cells: insights from the meta-analysis of microarray data from multiple mouse cell populations

scientific article

Follicular dendritic cell dedifferentiation by treatment with an inhibitor of the lymphotoxin pathway dramatically reduces scrapie susceptibility

scientific article

Follicular dendritic cell dedifferentiation reduces scrapie susceptibility following inoculation via the skin

scientific article published in February 2005

Follicular dendritic cell-specific prion protein (PrP) expression alone is sufficient to sustain prion infection in the spleen

scientific article published on December 2011

Follicular dendritic cells as targets for intervention in transmissible spongiform encephalopathies.

scientific article

Follicular dendritic cells in TSE pathogenesis

scientific article published on 01 September 2000

How do PrPSc Prions Spread between Host Species, and within Hosts?

scientific article

Human prion diseases and the risk of their transmission during anatomical dissection

scientific article published on 17 April 2014

Identification of co-expressed gene signatures in mouse B1, marginal zone and B2 B-cell populations

scientific article published on January 2014

Identification of novel genes selectively expressed in the follicle-associated epithelium from the meta-analysis of transcriptomics data from multiple mouse cell and tissue populations.

scientific article

In Vivo Depletion of CD11c+ Cells Impairs Scrapie Agent Neuroinvasion from the Intestine

scientific article published on 01 December 2007

Increased Abundance of M Cells in the Gut Epithelium Dramatically Enhances Oral Prion Disease Susceptibility

scientific article

Increased susceptibility to oral Trichuris muris infection in the specific absence of CXCR5 CD11c cells

scientific article published on 01 August 2018

Influence of ageing on the microarchitecture of the spleen and lymph nodes

scientific article published on 13 May 2017

Inhibition of nitric oxide synthesis leads to reduced parasitemia in murine Trypanosoma brucei infection.

scientific article published on May 1994

Inside-out chicken enteroids with leukocyte component as a model to study host-pathogen interactions

scientific article published on 19 March 2021

Involvement of the immune system in TSE pathogenesis

scientific article published on 01 May 1998

Isolated lymphoid follicle maturation induces the development of follicular dendritic cells

article

M cell-depletion blocks oral prion disease pathogenesis.

scientific article

Meta-analysis of lineage-specific gene expression signatures in mouse leukocyte populations

article

MicroRNA-100-5p indirectly modulates the expression of Il6, Ptgs1/2 and Tlr4 mRNA in the mouse follicular dendritic cell-like cell line, FL-Y.

scientific article

Migrating intestinal dendritic cells transport PrP(Sc) from the gut.

scientific article published in January 2002

Monocyte-derived Prostaglandin E2 inhibits antigen-specific cutaneous immunity during ageing

scientific article published on 03 April 2020

Neuroinvasion by scrapie following inoculation via the skin is independent of migratory Langerhans cells

scientific article

Nitric oxide produced in the lungs of mice immunized with the radiation-attenuated schistosome vaccine is not the major agent causing challenge parasite elimination

scientific article published on 01 January 1998

Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells

scientific article

Oral Prion Neuroinvasion Occurs Independently of PrP Expression in the Gut Epithelium

scholarly article by Alison Marshall published in October 2018

Peripheral prion disease pathogenesis is unaltered in the absence of sialoadhesin (Siglec-1/CD169).

scientific article published on September 2014

Pleiotropic Impacts of Macrophage and Microglial Deficiency on Development in Rats with Targeted Mutation of the Locus

scientific article published on 24 September 2018

Pleiotropic effects of extended blockade of CSF1R signaling in adult mice.

scientific article

Prion disease and the innate immune system

scientific article published on December 2012

Prion disease: bridging the spleen-nerve gap

scientific article published on 01 December 2003

Prion pathogenesis and secondary lymphoid organs (SLO): tracking the SLO spread of prions to the brain

scientific article

Prion uptake in the gut: identification of the first uptake and replication sites

scientific article (publication date: December 2011)

Prions and the blood and immune systems.

scientific article

Prions and their lethal journey to the brain

scientific article

Prospects for safe and effective vaccines against prion diseases

scientific article published on 30 September 2014

Reciprocal regulation of lymphoid tissue development in the large intestine by IL-25 and IL-23.

scientific article published on 24 September 2014

Role of the GALT in scrapie agent neuroinvasion from the intestine

scientific article published in March 2007

Role of the draining lymph node in scrapie agent transmission from the skin

scientific article published on 31 January 2007

Salmonella Transforms Follicle-Associated Epithelial Cells into M Cells to Promote Intestinal Invasion

scientific article (publication date: November 2012)

Scrapie affects the maturation cycle and immune complex trapping by follicular dendritic cells in mice

scientific article

Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells

scientific article published on 01 November 1999

Scrapie transmission following exposure through the skin is dependent on follicular dendritic cells in lymphoid tissues

scientific article

Sestrins induce natural killer function in senescent-like CD8+ T cells

scientific article published on 30 March 2020

Shiga toxin sub-type 2a increases the efficiency of Escherichia coli O157 transmission between animals and restricts epithelial regeneration in bovine enteroids

scientific article published on 03 October 2019

Skin-derived dendritic cells acquire and degrade the scrapie agent following in vitro exposure

scientific article published on September 2005

Structural and functional changes to lymph nodes in ageing mice

scientific article

T lymphocyte activation and the cellular form of the prion protein, PrPc

scientific article published on 01 May 1997

Temporal Profiling of the Cortical Synaptic Mitochondrial Proteome Identifies Ageing Associated Regulators of Stability

scientific article published in 2021

Temporary blockade of the tumor necrosis factor receptor signaling pathway impedes the spread of scrapie to the brain

scientific article published on May 2002

Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie.

scientific article

Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie

scientific article published on 01 July 2000

The Characterization of Varicella Zoster Virus-Specific T Cells in Skin and Blood during Aging

scientific article published on 3 March 2015

The Effects of Immune System Modulation on Prion Disease Susceptibility and Pathogenesis

scientific article published on 02 October 2020

The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

scientific article published on 8 July 2015

The MacBlue binary transgene (csf1r-gal4VP16/UAS-ECFP) provides a novel marker for visualisation of subsets of monocytes, macrophages and dendritic cells and responsiveness to CSF1 administration

scientific article

The complement system in prion diseases

scientific article published in October 2004

The diverse roles of mononuclear phagocytes in prion disease pathogenesis

scientific article

The effects of host age on follicular dendritic cell status dramatically impair scrapie agent neuroinvasion in aged mice

scientific article published on 28 September 2009

The effects of host age on the transport of complement-bound complexes to the spleen and the pathogenesis of intravenous scrapie infection

scientific article published on 26 October 2011

The functional maturation of M cells is dramatically reduced in the Peyer's patches of aged mice

scientific article published on 30 January 2013

The immunobiology of TSE diseases.

scientific article

The role of CSF1R-dependent macrophages in control of the intestinal stem-cell niche

scientific article published on 28 March 2018

The transmissible spongiform encephalopathies: pathogenic mechanisms and strategies for therapeutic intervention

scientific article

Trypanosoma brucei is protected from the cytostatic effects of nitric oxide under in vivo conditions.

scientific article published in January 1994

Type I interferon induces CXCL13 to support ectopic germinal center formation

scholarly article by Alice E. Denton et al published 4 March 2019 in Journal of Experimental Medicine

T‐lymphocyte activation and the cellular form of the prion protein

scientific article published on 01 October 1997

Unaltered intravenous prion disease pathogenesis in the temporary absence of marginal zone B cells

scientific article published on 13 December 2019

c-Rel is dispensable for the differentiation and functional maturation of M cells in the follicle-associated epithelium

scientific article published on 18 September 2016

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