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List of works by Francisco Blanco-vaca

A genomewide exploration suggests a new candidate gene at chromosome 11q23 as the major determinant of plasma homocysteine levels: results from the GAIT project

scientific article

ATP-binding cassette G5/G8 deficiency causes hypertriglyceridemia by affecting multiple metabolic pathways.

scientific article published on 10 August 2011

Acute Psychological Stress Accelerates Reverse Cholesterol Transport via Corticosterone-Dependent Inhibition of Intestinal Cholesterol Absorption ⬇️

scientific article published on August 28, 2012

Adiponectin: a new link between obesity, insulin resistance and cardiovascular disease

scientific article

Administration of CORM-2 inhibits diabetic neuropathy but does not reduce dyslipidemia in diabetic mice

scientific article published in PLoS ONE

Alterations in the protein content and dysfunction of high-density lipoproteins from hyperhomocysteinemic mice

scientific article published on 12 August 2013

Antiatherogenic potential of ezetimibe in sitosterolemia: Beyond plant sterols lowering.

scientific article

Apo(B)-dependent dyslipidemic phenotypes in type 1 diabetic patients.

scientific article published in December 2001

ApoA-I mimetic administration, but not increased apoA-I-containing HDL, inhibits tumour growth in a mouse model of inherited breast cancer.

scientific article

Apolipoprotein A-II, genetic variation on chromosome 1q21-q24, and disease susceptibility

scientific article published on June 2004

Apolipoprotein A5 S19W may play a role in dysbetalipoproteinemia in patients with the Apo E2/E2 genotype

scientific article published on 01 October 2006

Apolipoprotein modulation of streptococcal serum opacity factor activity against human plasma high-density lipoproteins.

scientific article published on August 2009

Are LXR-regulated genes a major molecular target of plant sterols/stanols?

scientific article published on 12 January 2007

Atorvastatin does not decrease or delay diabetes onset in two different mouse models of type 1 diabetes

scientific article published on 30 June 2005

Bariatric surgery in morbidly obese patients improves the atherogenic qualitative properties of the plasma lipoproteins

scientific article published on 14 March 2014

Basic mechanisms: structure, function and metabolism of plasma lipoproteins

scientific article published in April 2013

CETP activity variation in mice does not affect two major HDL antiatherogenic properties: macrophage-specific reverse cholesterol transport and LDL antioxidant protection

scientific article published on 22 June 2007

Changes in intestinal and liver global gene expression in response to a phytosterol-enriched diet

scientific article published on 12 February 2005

Changes in low-density lipoprotein electronegativity and oxidizability after aerobic exercise are related to the increase in associated non-esterified fatty acids

scientific article published in January 2002

Chronic intermittent psychological stress promotes macrophage reverse cholesterol transport by impairing bile acid absorption in mice

scientific article

Chylomicrons: Advances in biology, pathology, laboratory testing, and therapeutics.

scientific article published on 08 February 2016

Clinically used selective estrogen receptor modulators affect different steps of macrophage-specific reverse cholesterol transport

scientific article published on 07 September 2016

Consumption of polyunsaturated fat improves the saturated fatty acid-mediated impairment of HDL antioxidant potential

scientific article published on 29 June 2015

Deficiency in monocyte chemoattractant protein-1 modifies lipid and glucose metabolism

scientific article published on 31 August 2007

Determination and utilisation of the plasmatic concentration of homocysteine in clinical practice

scientific article published in April 2005

Dietary phytosterols modulate T-helper immune response but do not induce apparent anti-inflammatory effects in a mouse model of acute, aseptic inflammation

scientific article published on 01 March 2007

Differential effects of gemfibrozil and fenofibrate on reverse cholesterol transport from macrophages to feces in vivo.

scientific article published on 30 November 2010

Differential intestinal mucosal protein expression in hypercholesterolemic mice fed a phytosterol-enriched diet

scholarly article by Laura Calpe-Berdiel published in August 2007

Direct evidence in vivo of impaired macrophage-specific reverse cholesterol transport in ATP-binding cassette transporter A1-deficient mice

scientific article published on 27 December 2005

Disodium ascorbyl phytostanol phosphate (FM-VP4), a modified phytostanol, is a highly active hypocholesterolaemic agent that affects the enterohepatic circulation of both cholesterol and bile acids in mice

scientific article published on 13 October 2009

Disulfide linked dimers of apolipoprotein D in urine

scientific article published on 01 October 1993

Effect of PPAR-β/δ agonist GW0742 treatment in the acute phase response and blood-brain barrier permeability following brain injury

scientific article published on 18 October 2016

Effect of atorvastatin on lipoprotein (a) and interleukin-10: A randomized placebo-controlled trial

scientific article published on 04 December 2010

Effect of improving glycemic control in patients with type 2 diabetes mellitus on low-density lipoprotein size, electronegative low-density lipoprotein and lipoprotein-associated phospholipase A2 distribution

scientific article published on 3 April 2012

Effect of simvastatin treatment on the electronegative low-density lipoprotein present in patients with heterozygous familial hypercholesterolemia

scientific article

Effects of site-directed mutagenesis on the serine residues of human lecithin:cholesterol acyltransferase

scientific article published on 01 December 1994

Emerging cardiovascular risk factors in subclinical hypothyroidism: lack of change after restoration of euthyroidism.

scientific article published in November 2004

Enhanced vascular permeability facilitates entry of plasma HDL and promotes macrophage-reverse cholesterol transport from skin in mice.

scientific article

Evaluation of two nonisotopic immunoassays for determination of glutamic acid decarboxylase and tyrosine phosphatase autoantibodies in serum

scientific article

Folic acid supplementation delays atherosclerotic lesion development in apoE-deficient mice

scientific article published on 10 November 2006

Functional lecithin:cholesterol acyltransferase deficiency and high density lipoprotein deficiency in transgenic mice overexpressing human apolipoprotein A-II

scientific article

Genetic analysis does not confirm non-classical congenital adrenal hyperplasia in more than a third of the women followed with this diagnosis

scientific article published on 01 October 2014

Genetically based hypertension generated through interaction of mild hypoalphalipoproteinemia and mild hyperhomocysteinemia

scientific article published on 01 August 2007

Genome-wide linkage analysis for identifying quantitative trait loci involved in the regulation of lipoprotein a (Lpa) levels

scientific article published on 18 June 2008

HDL and lifestyle interventions

scientific article

Hepatic lipase- and endothelial lipase-deficiency in mice promotes macrophage-to-feces RCT and HDL antioxidant properties.

scientific article published on 15 January 2013

High-density lipoprotein cholesterol targeting for novel drug discovery: where have we gone wrong?

scientific article published on 12 December 2013

Homocyst(e)ine and the C677T mutation of methylenetetrahydrofolate reductase in survivors of premature myocardial infarction

scientific article published on 01 August 2000

Homocysteine and cognitive impairment. Relation with diagnosis and neuropsychological performance

scientific article published on 20 November 2008

Homozygous Familial Hypercholesterolemia in Spain: Prevalence and Phenotype-Genotype Relationship

scientific article

Human ApoA-I Overexpression Enhances Macrophage-Specific Reverse Cholesterol Transport but Fails to Prevent Inherited Diabesity in Mice ⬇️

scientific article published on 02 February 2019

Human apolipoprotein A-II determines plasma triglycerides by regulating lipoprotein lipase activity and high-density lipoprotein proteome.

scientific article

Human apolipoprotein A-II enrichment displaces paraoxonase from HDL and impairs its antioxidant properties: a new mechanism linking HDL protein composition and antiatherogenic potential.

scientific article published on 23 September 2004

Human hepatic lipase overexpression in mice induces hepatic steatosis and obesity through promoting hepatic lipogenesis and white adipose tissue lipolysis and fatty acid uptake

scientific article published on 15 December 2017

Human scavenger protein AIM increases foam cell formation and CD36-mediated oxLDL uptake.

scientific article published on 2 December 2013

Identification and quantification of apolipoproteins in addition to apo[a] and apo B-100 in human lipoprotein[a]

scientific article published on 01 January 1994

Identification of ZNF366 and PTPRD as novel determinants of plasma homocysteine in a family-based genome-wide association study

scientific article published on 12 June 2009

Identification of a novel mutation in the ANGPTL3 gene in two families diagnosed of familial hypobetalipoproteinemia without APOB mutation

scientific article published on 29 November 2011

Increased production of very-low-density lipoproteins in transgenic mice overexpressing human apolipoprotein A-II and fed with a high-fat diet

scientific article published in November 2000

LXR-dependent regulation of macrophage-specific reverse cholesterol transport is impaired in a model of genetic diabesity.

scientific article published on 18 May 2017

Latent autoimmune diabetes in adults is perched between type 1 and type 2: evidence from adults in one region of Spain

scientific article published in September 2013

Lipoprotein hydrophobic core lipids are partially extruded to surface in smaller HDL: "Herniated" HDL, a common feature in diabetes

scientific article published on 18 January 2016

Liver X receptor-mediated activation of reverse cholesterol transport from macrophages to feces in vivo requires ABCG5/G8.

scientific article published on 28 May 2008

Low-density lipoprotein particle size, triglyceride-rich lipoproteins, and glucose tolerance in non-diabetic men with essential hypertension.

scientific article published in August 2001

Manipulation of inflammation modulates hyperlipidemia in apolipoprotein E-deficient mice: A possible role for interleukin-6

scientific article published on 01 May 2006

Mast cell activation in vivo impairs the macrophage reverse cholesterol transport pathway in the mouse

scientific article published on 6 January 2011

Mechanisms of HDL deficiency in mice overexpressing human apoA-II.

scientific article published in October 2002

Methionine-induced hyperhomocysteinemia impairs the antioxidant ability of high-density lipoproteins without reducing in vivo macrophage-specific reverse cholesterol transport.

scientific article published on 10 June 2013

Moderate beer consumption does not change early or mature atherosclerosis in mice

scientific article

Modulation of autoimmune arthritis severity in mice by apolipoprotein E (ApoE) and cholesterol.

scientific article published on 29 August 2016

Molecular Diagnosis of Lecithin: Cholesterol Acyltransferase Deficiency in a Presymptomatic Proband ⬇️

scientific article published on June 1, 1998

Molecular analysis of chylomicronemia in a clinical laboratory setting: diagnosis of 13 cases of lipoprotein lipase deficiency.

scientific article published in December 2013

Molecular pathology of multiple endocrine neoplasia type I: two novel germline mutations and updated classification of mutations affecting MEN1 gene.

scientific article

Nicotinamide Prevents Apolipoprotein B-Containing Lipoprotein Oxidation, Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice

scientific article published on 21 November 2020

Overexpression of human apolipoprotein A-II in transgenic mice does not increase their susceptibility to insulin resistance and obesity.

scientific article

PPAR-β/δ activation promotes phospholipid transfer protein expression.

scientific article

Paradoxical exacerbation of combined hyperlipidemia in human apolipoprotein A-II transgenic mice treated with fenofibrate

scientific article

Patient presenting multiple consecutive venous and arterial thrombotic events despite intensive conventional treatment: response after normalization of plasma homocysteine and N-acetylcysteine therapy

scientific article published in October 2003

Patients with MEN-1 are more insulin-resistant than their non-affected relatives

scientific article published in November 2005

Phenytoin treatment reduces atherosclerosis in mice through mechanisms independent of plasma HDL-cholesterol concentration.

scientific article

Phytosterol-mediated inhibition of intestinal cholesterol absorption in mice is independent of liver X receptor

scientific article

Phytosterol-mediated inhibition of intestinal cholesterol absorption is independent of ATP-binding cassette transporter A1.

scientific article published in March 2006

Phytosterols do not change susceptibility to obesity, insulin resistance, and diabetes induced by a high-fat diet in mice

scientific article

Phytosterols inhibit the tumor growth and lipoprotein oxidizability induced by a high-fat diet in mice with inherited breast cancer.

scientific article published on 30 May 2012

Plasma homocysteine is related to albumin excretion rate in patients with diabetes mellitus: a new link between diabetic nephropathy and cardiovascular disease?

scientific article published in June 1998

Platelet-Activating Factor Acetylhydrolase Is Mainly Associated With Electronegative Low-Density Lipoprotein Subfraction

scientific article published on 23 June 2003

Quantification of In Vitro Macrophage Cholesterol Efflux and In Vivo Macrophage-Specific Reverse Cholesterol Transport.

scientific article published on January 2015

Remarkable quantitative and qualitative differences in HDL after niacin or fenofibrate therapy in type 2 diabetic patients

scientific article published on 09 December 2014

Resveratrol administration or SIRT1 overexpression does not increase LXR signaling and macrophage-to-feces reverse cholesterol transport in vivo.

scientific article

Role of vitamin D in the pathogenesis of type 2 diabetes mellitus

scientific article published on March 2008

Seeking Novel Targets for Improving In Vivo Macrophage-Specific Reverse Cholesterol Transport: Translating Basic Science into New Therapies for the Prevention and Treatment of Atherosclerosis

scientific article published on 01 March 2011

Serum soluble transferrin receptor concentrations are increased in central obesity. Results from a screening programme for hereditary hemochromatosis in men with hyperferritinemia.

scientific article

Sitosterolemia: diagnosis, investigation, and management

scientific article

Structural and functional analysis of APOA5 mutations identified in patients with severe hypertriglyceridemia.

scientific article published on 10 January 2013

Structure of human apolipoprotein D: locations of the intermolecular and intramolecular disulfide links

scientific article

The Cholesterol Content of Western Diets Plays a Major Role in the Paradoxical Increase in High-Density Lipoprotein Cholesterol and Upregulates the Macrophage Reverse Cholesterol Transport Pathway

scientific article published on 01 November 2011

The effects of liposuction removal of subcutaneous abdominal fat on lipid metabolism are independent of insulin sensitivity in normal-overweight individuals

scientific article published on 9 February 2008

Turpentine-induced inflammation reduces the hepatic expression of the multiple drug resistance gene, the plasma cholesterol concentration and the development of atherosclerosis in apolipoprotein E deficient mice

scientific article (publication date: 15 April 2005)

[Co-existence of cardiovascular risk factors in patients with diabetes and peripheral vascular disease]

scientific article published on 01 July 2016

[Early cancer diagnosis through proteomics of serum: fiction or fact?]

scientific article published on 01 February 2005

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