List of works - Michael Hough

A Histidine Residue and a Tetranuclear Cuprous-thiolate Cluster Dominate the Copper Loading Landscape of a Copper Storage Protein from Streptomyces lividans

scientific article published on 09 July 2019

A QM/MM Study of Nitrite Binding Modes in a Three-Domain Heme-Cu Nitrite Reductase

scientific article published on 16 November 2018

A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans

scientific article published on 2 January 2018

A subtle structural change in the distal haem pocket has a remarkable effect on tuning hydrogen peroxide reactivity in dye decolourising peroxidases from Streptomyces lividans

scientific article published on 16 January 2020

Active site structures and the redox properties of blue copper proteins: atomic resolution structure of azurin II and electronic structure calculations of azurin, plastocyanin and stellacyanin

scientific article published on 23 February 2006

Active-site maturation and activity of the copper-radical oxidase GlxA are governed by a tryptophan residue.

scientific article published on 16 January 2017

Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase

scientific article published on 16 June 2017

An Aromatic Dyad Motif in Dye Decolourising Peroxidases Has Implications for Free Radical Formation and Catalysis

scientific article published on 04 April 2019

Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells.

scientific article

Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data.

scientific article

Challenges of sulfur SAD phasing as a routine method in macromolecular crystallography

scientific article published on 29 November 2011

Conformational control of the binding of diatomic gases to cytochrome c'

scientific article

Conformational variability of the Cu site in one subunit of bovine CuZn superoxide dismutase: the importance of mobility in the Glu119-Leu142 loop region for catalytic function

scientific article

Crystal structures of the Met148Leu and Ser86Asp mutants of rusticyanin from Thiobacillus ferrooxidans: insights into the structural relationship with the cupredoxins and the multi copper proteins

scientific article

Crystallographic structures of bovine copper-zinc superoxide dismutase reveal asymmetry in two subunits: functionally important three and five coordinate copper sites captured in the same crystal

scientific article

Crystallography with online optical and X-ray absorption spectroscopies demonstrates an ordered mechanism in copper nitrite reductase

scientific article

Cytochromes c': Structure, Reactivity and Relevance to Haem-Based Gas Sensing.

scientific article

Demonstration of proton-coupled electron transfer in the copper-containing nitrite reductases

scientific article published on 7 July 2009

Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

scholarly article

Distal-to-proximal NO conversion in hemoproteins: the role of the proximal pocket

scientific article

Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins

scientific article published on 03 May 2019

Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design.

scientific article

Enzyme catalysis captured using multiple structures from one crystal at varying temperatures.

scientific article

Fingerprinting redox and ligand states in haemprotein crystal structures using resonance Raman spectroscopy

scientific article

From crystal to structure with CCP4.

scientific article published in February 2018

GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of Streptomyces lividans

scientific article

Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases ⬇️

scientific article published on 15 April 2016

High Resolution Structural Studies of Mutants Provide Insights into Catalysis and Electron Transfer Processes in Copper Nitrite Reductase

article

High-throughput structures of protein-ligand complexes at room temperature using serial femtosecond crystallography

scientific article published on 10 October 2019

Hydrogen bonding of the dissociated histidine ligand is not required for formation of a proximal NO adduct in cytochrome c'

scientific article

Hydroxylamine Complexes of Cytochrome c': Influence of Heme Iron Redox State on Kinetic and Spectroscopic Properties

scientific article published on 24 September 2020

Identification of the proton channel to the active site type 2 Cu center of nitrite reductase: structural and enzymatic properties of the His254Phe and Asn90Ser mutants

scientific article

Implementation of cluster analysis for ab initio phasing using the molecular envelope from solution X-ray scattering

scientific article published on 01 August 2000

Insights into redox partner interactions and substrate binding in nitrite reductase from Alcaligenes xylosoxidans: crystal structures of the Trp138His and His313Gln mutants.

scientific article published in December 2004

Interaction of Azole-Based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: A Molecular Basis for Toxicity

scientific article published on 7 April 2017

Modulation of ligand-heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond-second temporal range.

scientific article published on 11 October 2013

Monitoring and validating active site redox states in protein crystals

scientific article

NO binding to the proapoptotic cytochrome c-cardiolipin complex.

scientific article published on January 2014

Nature of the copper-nitrosyl intermediates of copper nitrite reductases during catalysis

scientific article published on 20 October 2020

On-line optical and X-ray spectroscopies with crystallography: an integrated approach for determining metalloprotein structures in functionally well defined states

scientific article

One fold, two functions: cytochrome P460 and cytochrome '-β from the methanotroph (Bath)

scientific article published on 21 January 2019

Photoreduction and validation of haem-ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction

scientific article

Recent structural insights into the function of copper nitrite reductases.

scientific article

Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography

scientific article published on 09 November 2018

Resonance Raman Spectra of Five-Coordinate Heme-Nitrosyl Cytochromes c': Effect of the Proximal Heme-NO Environment.

scientific article published on 22 May 2015

Response to Copper Stress in Streptomyces lividans Extends beyond Genes under Direct Control of a Copper-sensitive Operon Repressor Protein (CsoR)

scientific article

Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal

scientific article

Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase

scientific article

Structural and mechanistic insights into an extracytoplasmic copper trafficking pathway in Streptomyces lividans

scientific article

Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg.

scientific article published on May 2005

Structural insights into conformational switching in the copper metalloregulator CsoR from Streptomyces lividans

scientific article

Structure of fully reduced bovine copper zinc superoxide dismutase at 1.15 A

scientific article

Structure of the M148Q mutant of rusticyanin at 1.5 Å: a model for the copper site of stellacyanin

article

The <i>CCP</i>4 suite: integrative software for macromolecular crystallography

scientific article published in 2023

The benefit of the European User Community from transnational access to national radiation facilities

scientific article

The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant

scientific article

The structure of a class 3 nonsymbiotic plant haemoglobin from Arabidopsis thaliana reveals a novel N-terminal helical extension

scientific article

The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis

scientific article (publication date: 9 May 2003)

The structure of the Met144Leu mutant of copper nitrite reductase from Alcaligenes xylosoxidans provides the first glimpse of a protein-protein complex with azurin II

scientific article

Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu–Zn, Zn–Zn and As-isolated Wild-type Enzymes

scientific article published on 12 December 2005

List of works by Michael Hough

A Histidine Residue and a Tetranuclear Cuprous-thiolate Cluster Dominate the Copper Loading Landscape of a Copper Storage Protein from Streptomyces lividans

A QM/MM Study of Nitrite Binding Modes in a Three-Domain Heme-Cu Nitrite Reductase

A cytosolic copper storage protein provides a second level of copper tolerance in Streptomyces lividans

A subtle structural change in the distal haem pocket has a remarkable effect on tuning hydrogen peroxide reactivity in dye decolourising peroxidases from Streptomyces lividans

Active site structures and the redox properties of blue copper proteins: atomic resolution structure of azurin II and electronic structure calculations of azurin, plastocyanin and stellacyanin

Active-site maturation and activity of the copper-radical oxidase GlxA are governed by a tryptophan residue.

Active-site protein dynamics and solvent accessibility in native Achromobacter cycloclastes copper nitrite reductase

An Aromatic Dyad Motif in Dye Decolourising Peroxidases Has Implications for Free Radical Formation and Catalysis

Antiandrogens act as selective androgen receptor modulators at the proteome level in prostate cancer cells.

Challenges and solutions for the analysis of in situ, in crystallo micro-spectrophotometric data.

Challenges of sulfur SAD phasing as a routine method in macromolecular crystallography

Conformational control of the binding of diatomic gases to cytochrome c'

Conformational variability of the Cu site in one subunit of bovine CuZn superoxide dismutase: the importance of mobility in the Glu119-Leu142 loop region for catalytic function

Crystal structures of the Met148Leu and Ser86Asp mutants of rusticyanin from Thiobacillus ferrooxidans: insights into the structural relationship with the cupredoxins and the multi copper proteins

Crystallographic structures of bovine copper-zinc superoxide dismutase reveal asymmetry in two subunits: functionally important three and five coordinate copper sites captured in the same crystal

Crystallography with online optical and X-ray absorption spectroscopies demonstrates an ordered mechanism in copper nitrite reductase

Cytochromes c': Structure, Reactivity and Relevance to Haem-Based Gas Sensing.

Demonstration of proton-coupled electron transfer in the copper-containing nitrite reductases

Dimer destabilization in superoxide dismutase may result in disease-causing properties: structures of motor neuron disease mutants.

Distal-to-proximal NO conversion in hemoproteins: the role of the proximal pocket

Dose-resolved serial synchrotron and XFEL structures of radiation-sensitive metalloproteins

Engineering proximal vs. distal heme-NO coordination via dinitrosyl dynamics: implications for NO sensor design.

Enzyme catalysis captured using multiple structures from one crystal at varying temperatures.

Fingerprinting redox and ligand states in haemprotein crystal structures using resonance Raman spectroscopy

From crystal to structure with CCP4.

GlxA is a new structural member of the radical copper oxidase family and is required for glycan deposition at hyphal tips and morphogenesis of Streptomyces lividans

Heterogeneity in the Histidine-brace Copper Coordination Sphere in Auxiliary Activity Family 10 (AA10) Lytic Polysaccharide Monooxygenases ⬇️

High Resolution Structural Studies of Mutants Provide Insights into Catalysis and Electron Transfer Processes in Copper Nitrite Reductase

High-throughput structures of protein-ligand complexes at room temperature using serial femtosecond crystallography

Hydrogen bonding of the dissociated histidine ligand is not required for formation of a proximal NO adduct in cytochrome c'

Hydroxylamine Complexes of Cytochrome c': Influence of Heme Iron Redox State on Kinetic and Spectroscopic Properties

Identification of the proton channel to the active site type 2 Cu center of nitrite reductase: structural and enzymatic properties of the His254Phe and Asn90Ser mutants

Implementation of cluster analysis for ab initio phasing using the molecular envelope from solution X-ray scattering

Insights into redox partner interactions and substrate binding in nitrite reductase from Alcaligenes xylosoxidans: crystal structures of the Trp138His and His313Gln mutants.

Interaction of Azole-Based Environmental Pollutants with the Coelomic Hemoglobin from Amphitrite ornata: A Molecular Basis for Toxicity

Modulation of ligand-heme reactivity by binding pocket residues demonstrated in cytochrome c' over the femtosecond-second temporal range.

Monitoring and validating active site redox states in protein crystals

NO binding to the proapoptotic cytochrome c-cardiolipin complex.

Nature of the copper-nitrosyl intermediates of copper nitrite reductases during catalysis

On-line optical and X-ray spectroscopies with crystallography: an integrated approach for determining metalloprotein structures in functionally well defined states

One fold, two functions: cytochrome P460 and cytochrome '-β from the methanotroph (Bath)

Photoreduction and validation of haem-ligand intermediate states in protein crystals by in situ single-crystal spectroscopy and diffraction

Recent structural insights into the function of copper nitrite reductases.

Resolving polymorphs and radiation-driven effects in microcrystals using fixed-target serial synchrotron crystallography

Resonance Raman Spectra of Five-Coordinate Heme-Nitrosyl Cytochromes c': Effect of the Proximal Heme-NO Environment.

Response to Copper Stress in Streptomyces lividans Extends beyond Genes under Direct Control of a Copper-sensitive Operon Repressor Protein (CsoR)

Serial crystallography captures enzyme catalysis in copper nitrite reductase at atomic resolution from one crystal

Structural Evidence for a Copper-Bound Carbonate Intermediate in the Peroxidase and Dismutase Activities of Superoxide Dismutase

Structural and mechanistic insights into an extracytoplasmic copper trafficking pathway in Streptomyces lividans

Structural consequences of the familial amyotrophic lateral sclerosis SOD1 mutant His46Arg.

Structural insights into conformational switching in the copper metalloregulator CsoR from Streptomyces lividans

Structure of fully reduced bovine copper zinc superoxide dismutase at 1.15 A

Structure of the M148Q mutant of rusticyanin at 1.5 Å: a model for the copper site of stellacyanin

The <i>CCP</i>4 suite: integrative software for macromolecular crystallography

The benefit of the European User Community from transnational access to national radiation facilities

The hydrogen-peroxide-induced radical behaviour in human cytochrome c-phospholipid complexes: implications for the enhanced pro-apoptotic activity of the G41S mutant

The structure of a class 3 nonsymbiotic plant haemoglobin from Arabidopsis thaliana reveals a novel N-terminal helical extension

The structure of holo and metal-deficient wild-type human Cu, Zn superoxide dismutase and its relevance to familial amyotrophic lateral sclerosis

The structure of the Met144Leu mutant of copper nitrite reductase from Alcaligenes xylosoxidans provides the first glimpse of a protein-protein complex with azurin II

Variable Metallation of Human Superoxide Dismutase: Atomic Resolution Crystal Structures of Cu–Zn, Zn–Zn and As-isolated Wild-type Enzymes