Search filters

List of works by Sandro Sonnino

1H-NMR study on ganglioside amide protons: evidence that the deuterium exchange kinetics are affected by the preparation of samples.

scientific article published on December 1993

A new chemical procedure for the preparation of gangliosides carrying fluorescent or paramagnetic probes on the lipid moiety

scientific article published in May 1986

A photo-reactive derivative of ganglioside GM1 specifically cross-links VIP21-caveolin on the cell surface.

scientific article published on November 1995

A photoreactive derivative of radiolabeled GM1 ganglioside: preparation and use to establish the involvement of specific proteins in GM1 uptake by human fibroblasts in culture

scientific article published on 01 January 1989

A practical route to long-chain non-natural α,ω-diamino acids

scientific article published on 10 July 2012

A procedure for the preparation of GM3 ganglioside from GM1-lactone

scientific article published on 01 March 1999

Aberrant glycosphingolipid expression and membrane organization in tumor cells: consequences on tumor-host interactions

scientific article published on 01 January 2011

Absence of metabolic cross-correction in Tay-Sachs cells: implications for gene therapy

scientific article published on 28 March 2002

Activation of (Na+, K+)-ATPase by nanomolar concentrations of GM1 ganglioside

scientific article published on 01 August 1981

Activity of plasma membrane beta-galactosidase and beta-glucosidase

scientific article published on 4 July 2009

Age-related changes of the ganglioside long-chain base composition in rat cerebellum

scientific article published in February 1996

Aggregation properties of semisynthetic GD1a ganglioside (IV3Neu5ACII3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety

scientific article published on August 1, 1995

Aggregation properties of semisynthetic GM1 ganglioside (II3Neu5AcGgOse4Cer) containing an acetyl group as acyl moiety

scientific article published on 01 November 1990

Aggregative properties of gangliosides in solution

scientific article published in May 1994

Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A.

scientific article

Altered expression of ganglioside GM3 molecular species and a potential regulatory role during myoblast differentiation

scientific article published on 8 March 2017

Altered sphingolipid metabolism in N-(4-hydroxyphenyl)-retinamide-resistant A2780 human ovarian carcinoma cells

scientific article

Analysis of gangliosides using fast atom bombardment mass spectrometry

scientific article published in May 1985

Analytical and preparative high-performance liquid chromatography of gangliosides

scientific article published on 01 January 1984

Anti-GM1/GD1a complex antibodies in GBS sera specifically recognize the hybrid dimer GM1-GD1a.

scientific article

Association of Src-family protein tyrosine kinases with sphingolipids in rat cerebellar granule cells differentiated in culture

scientific article published on 01 March 2000

Association of gangliosides to fibroblasts in culture: A study performed with GM1 [14C]-labelled at the sialic acid acetyl group

article

Association of rat8 with Fyn protein kinase via lipid rafts is required for rat mammary cell differentiation in vitro

scholarly article

Behavior of gangliosides on dialysis.

scientific article

Bicistronic lentiviral vector corrects beta-hexosaminidase deficiency in transduced and cross-corrected human Sandhoff fibroblasts.

scientific article published on 13 June 2005

Biosynthesis of gangliosides containing C18:1 and C20:1 [3-14C]sphingosine after administrating [1-14C]palmitic acid and [1-14C]stearic acid to rat cerebellar granule cells in culture

scientific article published in May 1994

Brain lipid composition in grey-lethal mutant mouse characterized by severe malignant osteopetrosis

scientific article

Brain pathology in Niemann Pick disease type A: insights from the acid sphingomyelinase knockout mice

scientific article published on January 7, 2011

Carbohydrate dynamics at a micellar surface: GD1a headgroup transformations revealed by NMR spectroscopy.

scientific article

Carbohydrate epitope defined by an antitumor monoclonal antibody detected on glycoproteins and a glycolipid by immunoblotting

scientific article published on 01 January 1986

Cell surface sphingolipid glycohydrolases in neuronal differentiation and aging in culture

scientific article published on 07 January 2011

Ceramide and sphingomyelin species of fibroblasts and neurons in culture

article

Ceramide glycanase activities in human cancer cells

scientific article published on 01 October 1999

Ceramides as possible nutraceutical compounds: characterization of the ceramides of the Moro blood orange ( Citrus sinensis )

scientific article published on 01 October 2012

Changes in rabbit brain cytosolic and membrane-bound gangliosides during prenatal life.

scientific article published in January 1981

Changes in rabbit cerebrum and cerebellum gangliosides during postnatal life. A study especially referring to alkali labile gangliosides.

scientific article published in January 1984

Changes in the ceramide composition of rat forebrain gangliosides with age.

scientific article published in January 1990

Changes in the ganglioside long-chain base composition of rat cerebellar granule cells during differentiation and aging in culture

scientific article published in January 1993

Changes in the lipid turnover, composition, and organization, as sphingolipid-enriched membrane domains, in rat cerebellar granule cells developing in vitro

scientific article

Changes of the ganglioside pattern and content in human fibroblasts by high density cell population subculture progression.

scientific article

Changes of the human liver GM3 ganglioside molecular species during aging

article

Chaperone therapy for GM2 gangliosidosis: effects of pyrimethamine on β-hexosaminidase activity in Sandhoff fibroblasts.

scientific article published on 20 December 2013

Characterization of biotinylated liposomes sensitive to temperature and pH: new tools for anti-cancer drug delivery

scientific article published on 01 August 1996

Characterization of two molecular species GD3 ganglioside from bovine buttermilk

article

Conformation of the Oligosaccharide Chain of GM1 Ganglioside in a Carbohydrate-Enriched Surface

scientific article published on January 1, 1998

Cytosolic gangliosides of rat brain: Their fractionation into protein-bound complexes of different ganglioside compositions

article

Cytosolic gangliosides: occurrence in calf brain as ganglioside--protein complexes.

scientific article published on July 1979

Densitometric quantification of brain gangliosides separated by two-dimensional thin layer chromatography.

scientific article

Deregulated sphingolipid metabolism and membrane organization in neurodegenerative disorders.

scientific article published on 03 February 2010

Direct interaction, instrumental for signaling processes, between LacCer and Lyn in the lipid rafts of neutrophil-like cells.

scientific article published on 23 November 2014

Dynamic and structural properties of sphingolipids as driving forces for the formation of membrane domains.

scientific article published on June 2006

Dynamics of membrane lipid domains in neuronal cells differentiated in culture

scientific article published in August 2003

Effect of structural modifications of ganglioside GM2 on intra-molecular carbohydrate-to-carbohydrate interaction and enzymatic susceptibility.

scientific article published on 5 October 2007

Efflux of sphingolipids metabolically labeled with [1-3H]sphingosine, L-[3- 3H]serine and [9,10- 3H]palmitic acid from normal cells in culture.

scientific article

Electron paramagnetic resonance studies on the fluidity and surface dynamics of egg phosphatidylcholine vesicles containing gangliosides

article

Erratum to: Current and Novel Aspects on the Non-lysosomal β-Glucosylceramidase GBA2

scientific article published on 01 February 2016

Evaluation of the efficiency of an assay procedure for gangliosides in human serum

scientific article published in June 1996

Evidence that ganglioside enriched domains are distinct from caveolae in MDCK II and human fibroblast cells in culture

article

Exogenous gangliosides GD1b and GD1b-lactone, stably associated to rat brain P2 subcellular fraction, modulate differently the process of protein phosphorylation

scientific article published in October 1991

Exogenous sphingosine enters Xenopus laevis embryos grown in petri dishes and it is metabolized.

scientific article published in December 2001

Experimental evidence of a temperature-related conformational change of the hydrophilic portion of gangliosides

scientific article published on 01 March 1996

Exploring the link between ceramide and ionizing radiation

scientific article

Formation of a cytosolic ganglioside-protein complex following administration of photoreactive ganglioside GM1 to human fibroblasts in culture

scientific article published in April 1990

Formation of free sphingosine and ceramide from exogenous ganglioside GM1 by cerebellar granule cells in culture.

scientific article published on March 1992

Formation of tritium-labeled polysialylated gangliosides in the cytosol of rat cerebellar granule cells in culture following administration of [3H]GM1 ganglioside

scientific article published in December 1990

Frontiers in membrane biochemistry. Preface

scientific article published on 24 February 2010

Further studies on the changes of chicken brain gangliosides during prenatal and postnatal life

scientific article published in May 1990

Further studies on the gangliosidic nature of the cholinergic-specific antigen, Chol-1.

scientific article published in July 1990

GBA2-encoded β-glucosidase activity is involved in the inflammatory response to Pseudomonas aeruginosa.

scientific article

GM1 Ganglioside: Past Studies and Future Potential.

scientific article

GM1 ganglioside-triton X-100 mixed micelles Transitions among different micellar species monitored by physicochemical and enzymatic methods

scientific article published on 01 September 1980

GM1 promotes TrkA-mediated neuroblastoma cell differentiation by occupying a plasma membrane domain different from TrkA

scientific article published on 26 March 2019

GM1-ganglioside-Triton X-100 mixed micelles: changes of micellar properties studied by laser-light scattering and enzymatic methods.

scientific article published on May 1981

Galactose oxidase action on GM1 ganglioside in micellar and vesicular dispersions

scientific article

Ganglioside GM1 forces the redistribution of cholesterol in a biomimetic membrane.

scientific article

Gangliosides and the multiscale modulation of membrane structure

scientific article published on September 19, 2011

Gangliosides as components of lipid membrane domains.

scientific article published on 18 September 2006

Gangliosides as regulators of cell membrane organization and functions.

scientific article published on January 2010

Gangliosides as regulators of cell signaling: ganglioside-protein interactions or ganglioside-driven membrane organization?

scientific article published in February 2013

Gangliosides in the differentiation process of primary neurons: the specific role of GM1-oligosaccharide

scientific article published on 20 March 2020

Gel phase preference of ganglioside GM1 at low concentration in two-component, two-phase phosphatidylcholine bilayers depends upon the ceramide moiety

scientific article published on 01 May 1995

Geometrical and conformational properties of ganglioside GalNAc-GD1a, IV4GalNAcIV3Neu5AcII3Neu5AcGgOse4Cer.

scientific article published on October 1994

Identification of plasma membrane associated mature β-hexosaminidase A, active towards GM2 ganglioside, in human fibroblasts

scientific article published on 27 September 2005

Identification of the fenretinide metabolite 4-oxo-fenretinide present in human plasma and formed in human ovarian carcinoma cells through induction of cytochrome P450 26A1.

scientific article published on September 2004

Immunoseparation of sphingolipid-enriched membrane domains enriched in Src family protein tyrosine kinases and in the neuronal adhesion molecule TAG-1 by anti-GD3 ganglioside monoclonal antibody

scientific article

In vivo incorporation of D-glucose-U-C14 into tetrasialoganglioside in rat brain

scientific article published in April 1974

Induction of axonal differentiation by silencing plasma membrane-associated sialidase Neu3 in neuroblastoma cells.

scientific article published on 14 December 2006

Interaction of GM1 Ganglioside with Bovine Serum Albumin Formation and Isolation of Multiple Complexes

scientific article published on 01 October 1980

Interaction of Human Substantia Nigra Neuromelanin with Lipids and Peptides

Interaction of cholera toxin with gangliosides: differential effects of the oligosaccharide of ganglioside GM1 and of micellar gangliosides.

scientific article

Interaction of gangliosides with the methyltransferase-I of microsomes from normal and neoplastic human mammary gland

scientific article published in November 1992

Interactions between caveolin-1 and sphingolipids, and their functional relevance

scientific article published on 01 January 2012

Interactions between gangliosides and proteins in the exoplasmic leaflet of neuronal plasma membranes: a study performed with a tritium-labeled GM1 derivative containing a photoactivable group linked to the oligosaccharide chain.

scientific article

Interactions of ganglioside GM1 with human and fetal calf sera. Formation of ganglioside-serum albumin complexes

scientific article published on 01 October 1982

Involvement of very long fatty acid-containing lactosylceramide in lactosylceramide-mediated superoxide generation and migration in neutrophils

scientific article published on 28 November 2007

Ionizing radiations increase the activity of the cell surface glycohydrolases and the plasma membrane ceramide content.

scientific article published on 17 May 2012

Isolation and Analysis of Detergent-Resistant Membrane Fractions.

scientific article

Isolation and characterization of a tetrasialoganglioside from mouse brain, containing 9-O-acetyl,N-acetylneuraminic acid.

scientific article published in January 1982

Isolation and structural characterization of N-acetyl- and N-glycolylneuraminic-acid-containing GalNAc-GD1a isomers, IV4GalNAcIV3Neu5AcII3Neu5GcGgOse4Cer and IV4GalNAcIV3Neu5GcII3Neu5AcGgOse4Cer, from bovine brain

scientific article published on 01 December 1995

Lack of ceramide generation and altered sphingolipid composition are associated with drug resistance in human ovarian carcinoma cells

scientific article published on April 2006

Lack of the ganglioside molecular species containing the C20-long-chain bases in human, rat, mouse, rabbit, cat, dog, and chicken brains during prenatal life.

scientific article published in June 1991

Lactonization of GD1b ganglioside under acidic conditions

scientific article published on 01 October 1989

Laser-light scattering investigation of the micellar properties of gangliosides

scientific article published on April 1980

Laser-light scattering study of size and stability of ganglioside-phospholipid small unilamellar vesicles

Linalool modifies the nicotinic receptor-ion channel kinetics at the mouse neuromuscular junction

scientific article published on August 2000

Lipid membrane domains in the brain.

scientific article

Lipid rafts in neurodegeneration and neuroprotection

scientific article published on 22 December 2013

Lipid-based nanoparticles with high binding affinity for amyloid-beta1-42 peptide.

scientific article published in September 2010

Lipids and membrane lateral organization

scientific article

Lipoarabinomannan binding to lactosylceramide in lipid rafts is essential for the phagocytosis of mycobacteria by human neutrophils.

scientific article published on 11 October 2016

Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms

scientific article published on 30 November 2007

Membrane Domains and the “Lipid Raft” Concept

scientific article published on January 1, 2013

Membrane lipid domains in the nervous system.

scientific article published on January 2015

Metabolic processing of gangliosides by human fibroblasts in culture--formation and recycling of separate pools of sphingosine.

scientific article

Metabolic processing of gangliosides by normal and Salla human fibroblasts in culture. A study performed by administering radioactive GM3 ganglioside

scientific article published on 01 September 1996

Modeling ganglioside headgroups by conformational analysis and molecular dynamics.

scientific article

Modulation of cell functions by glycosphingolipid metabolic remodeling in the plasma membrane.

scientific article published on November 2007

Motor neuron disease in a patient with a monoclonal IgMk directed against GM1, GD1b, and high-molecular-weight neural-specific glycoproteins

scientific article published in August 1990

N-glycolyl GM1 ganglioside as a receptor for simian virus 40.

scientific article published on 12 September 2007

Nanoscale structural response of ganglioside-containing aggregates to the interaction with sialidase

scientific article published on 07 January 2011

Nervous system ganglioside composition of normothermic and hibernating dormice (Glis glis)

article

Neural precursor cell cultures from GM2 gangliosidosis animal models recapitulate the biochemical and molecular hallmarks of the brain pathology

scientific article

New approaches to the study of sphingolipid enriched membrane domains: the use of electron microscopic autoradiography to reveal metabolically tritium labeled sphingolipids in cell cultures

scientific article published on 01 March 2000

Nitric Oxide Boosts Chemoimmunotherapy via Inhibition of Acid Sphingomyelinase in a Mouse Model of Melanoma

article

Normal-phase high-performance liquid chromatographic separation of non-derivatized ganglioside mixtures

Nuclear Overhauser effect investigation on GM1 ganglioside containing N-glycolyl-neuraminic acid (II3Neu5GcGgOse4Cer).

scientific article published on February 1996

On the structure of a new, fucose containing ganglioside from pig cerebellum

scientific article

On the structure of two new gangliosides from beef brain

scientific article published in August 1976

Parkinson's disease recovery by GM1 oligosaccharide treatment in the B4galnt1+/- mouse model

scientific article published on 18 December 2019

Phosphatidic acid-mediated activation and translocation to the cell surface of sialidase NEU3, promoting signaling for cell migration

scientific article published on 12 February 2015

Phospholipid content and composition of human meningiomas

article

Photoactivable sphingosine as a tool to study membrane microenvironments in cultured cells

scientific article published on 10 October 2009

Plasma Membrane-Associated Glycohydrolases Along Differentiation of Murine Neural Stem Cells

scientific article published on 16 February 2012

Plasma membrane-associated glycohydrolases activation by extracellular acidification due to proton exchangers.

scientific article

Preparation of radioactive gangliosides, 3H or 14C isotopically labeled at oligosaccharide or ceramide moieties

scientific article published on 01 January 2000

Preparation of the tritiated molecular forms of gangliosides with homogeneous long chain base composition

article

Procedure for separation of GM2 ganglioside species with different ceramide structures by a flash reversed-phase silica gel liquid chromatography.

scientific article

Promotion of neuritogenesis in mouse neuroblastoma cells by exogenous gangliosides. Relationship between the effect and the cell association of ganglioside GM1.

scientific article

Rat cerebellar granule cells in culture associate and metabolize differently exogenous GM1 ganglioside molecular species containing a C18 or C20 long chain base

scientific article

Recognition by two-dimensional thin-layer chromatography and densitometric quantification of alkali-labile gangliosides from the brain of different animals

scientific article published on 01 January 1983

Remodeling of sphingolipids by plasma membrane associated enzymes.

scientific article published on 23 December 2010

Reorganization of prion protein membrane environment during low potassium-induced apoptosis in primary rat cerebellar neurons

scientific article published on 13 September 2007

Restoration of the GM2 ganglioside metabolism in bone marrow-derived stromal cells from Tay-Sachs disease animal model

scientific article published in August 2002

Role of gangliosides and plasma membrane-associated sialidase in the process of cell membrane organization

scientific article published on 01 January 2011

Role of the GM1 ganglioside oligosaccharide portion in the TrkA-dependent neurite sprouting in neuroblastoma cells.

scientific article

Role of very long fatty acid-containing glycosphingolipids in membrane organization and cell signaling: the model of lactosylceramide in neutrophils.

scientific article

Saposin B binds and transfers phospholipids

scientific article published on 6 February 2006

Second generation mimics of ganglioside GM1 as artificial receptors for cholera toxin: replacement of the sialic acid moiety.

scientific article published in October 2000

Secondary alterations of sphingolipid metabolism in lysosomal storage diseases.

scientific article published on 05 January 2011

Selected natural and synthetic retinoids impair CCR7- and CXCR4-dependent cell migration in vitro and in vivo

scientific article

Semisynthetic preparation of N-glycolylneuraminic acid containing GM1 ganglioside: chemical characterization, physico-chemical properties and some biochemical features

scientific article published on March 1, 1988

Separation of ganglioside molecular species, with homogeneous long-chain base composition, by reversed-phase thin-layer chromatography

article

Serum Antibodies to Glycans in Peripheral Neuropathies.

scientific article published on 11 February 2016

Sialic acid and GM3 ganglioside expression in papillomavirus-associated urinary bladder tumours of cattle with chronic enzootic haematuria

scientific article published on 12 July 2007

Specific ganglioside-cell protein interactions: a study performed with GM1 ganglioside derivative containing photoactivable azide and rat cerebellar granule cells in culture

scientific article published in April 1992

Specific recognition of N-acetylneuraminic acid in the GM2 epitope by human GM2 activator protein

scientific article published on 01 October 1995

Sphingolipid uptake by cultured cells: complex aggregates of cell sphingolipids with serum proteins and lipoproteins are rapidly catabolized.

scientific article

Sphingolipid-enriched Membrane Domains from Rat Cerebellar Granule Cells Differentiated in Culture

scientific article published in Journal of Biological Chemistry

Sphingolipidomics of A2780 human ovarian carcinoma cells treated with synthetic retinoids.

scientific article

Sphingolipids and membrane environments for caveolin.

scientific article published on 22 January 2009

Sphingolipids and neuronal degeneration in lysosomal storage disorders

scientific article published on 16 August 2018

Sphingosine kinase mediates resistance to the synthetic retinoid N-(4-hydroxyphenyl)retinamide in human ovarian cancer cells.

scientific article

Spontaneous transfer of GM3 ganglioside between vesicles

scientific article published on 01 August 1995

Spotlight on... Sandro Sonnino

scientific article published on 22 February 2008

Structural basis for the enzymatic resistance of the GM2 ganglioside

scientific article published on 01 January 2003

Structural basis for the resistance of Tay-Sachs ganglioside GM2 to enzymatic degradation

scientific article published in April 1999

Structure of the main ganglioside from the brain of Xenopus laevis

scientific article published in January 2002

Synthesis and aggregative properties of GM1 ganglioside (IV3Neu5AcGgOse4Cer) containing D-(+)-2-hydroxystearic acid.

scientific article published on February 1994

Synthesis and structural characterization of the dilactone derivative of GD1a ganglioside

scientific article published on 01 October 1988

Synthesis, structure, and conformation of the dilactone derivative of GD1b ganglioside

scientific article published on 01 December 1989

The Fourth ISN Special Neurochemistry Conference--"Membrane domains in CNS physiology and pathology", Erice, Trapani, Sicily, 22-26 May 2010

scientific article published on 01 March 2011

The Neuroprotective Role of the GM1 Oligosaccharide, II3Neu5Ac-Gg4, in Neuroblastoma Cells

scientific article published on 26 March 2019

The Role of 3-O-Sulfogalactosylceramide, Sulfatide, in the Lateral Organization of Myelin Membrane

scientific article

The anti-oligosaccharide antibodies present in sera from patients with motor neuron disease and neuropathy recognize the N-glycolylneuraminic acid containing gangliotetrahexosyl oligosaccharide

scientific article published on 01 October 1995

The galactocerebrosidase enzyme contributes to maintain a functional neurogenic niche during early post-natal CNS development

scientific article

The glycosphingolipid hydrolases in the central nervous system

scientific article

The membrane environment of endogenous cellular prion protein in primary rat cerebellar neurons

scientific journal article

The oxysterol-CXCR2 axis plays a key role in the recruitment of tumor-promoting neutrophils

scientific article

The plasma membrane-associated sialidase MmNEU3 modifies the ganglioside pattern of adjacent cells supporting its involvement in cell-to-cell interactions.

scientific article published on 16 February 2004

The role of sphingolipids in neuronal plasticity of the brain

scientific article published on 15 March 2016

The role of the ganglioside lipid moiety in the process of ganglioside-cell interactions

scientific article published in July 1992

The structural basis for the susceptibility of gangliosides to enzymatic degradation.

scientific article

Three dimensional structure of GD1b and GD1b-monolactone gangliosides in dimethylsulphoxide: a nuclear Overhauser effect investigation supported by molecular dynamics calculations.

scientific article published on September 1991

Tumor-mediated liver X receptor-alpha activation inhibits CC chemokine receptor-7 expression on dendritic cells and dampens antitumor responses

scientific article

Unravelling the role of sphingolipids in cystic fibrosis lung disease

scientific article

iPSC-derived neurons from GBA1-associated Parkinson's disease patients show autophagic defects and impaired calcium homeostasis

scientific article

Β-hexosaminidase over-expression affects lysosomal glycohydrolases expression and glycosphingolipid metabolism in mammalian cells.

scientific article published on 7 December 2011