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List of works by David Friedecký

A fatal combination: a thymidylate synthase inhibitor with DNA damaging activity

scientific article published on 11 February 2015

A lower dosage of imatinib is sufficient to maintain undetectable disease in patients with chronic myeloid leukemia with long-term low-grade toxicity of the treatment

scientific article published on 22 June 2015

A significant proportion of patients with chronic myeloid leukemia and suboptimal response according to European Leukemia Net criteria have excellent prognosis without treatment change.

scientific article

Analysis of aminoimidazole ribosides by capillary electrophoresis--diagnosing defects in second part of purine biosynthetic pathway.

scientific article published on 29 September 2006

Analysis of cytokinin nucleotides by capillary zone electrophoresis with diode array and mass spectrometric detection in a recombinant enzyme in vitro reaction

scientific article published on 05 September 2012

Analysis of intracellular nucleotides by capillary electrophoresis-mass spectrometry

scientific article published on 01 January 2006

Analytical derivatization-a tool for determination of orotic acid.

scientific article published in January 2004

Biomarkers of Neurodegenerative Diseases: Biology, Taxonomy, Clinical Relevance, and Current Research Status

scientific article published in 2022

Capillary electrophoresis determination of thiopurine methyl transferase activity in erythrocytes.

scientific article published on 13 May 2009

Capillary electrophoresis for detection of inherited disorders of purine and pyrimidine metabolism: a selective approach

scientific article published in February 2002

Capillary electrophoretic method for nucleotide analysis in cells: application on inherited metabolic disorders.

scientific article published in February 2007

Citrulline as a biomarker of gastrointestinal toxicity in patients with rectal carcinoma treated with chemoradiation.

scientific article published in February 2016

Detailed study of imatinib metabolization using high-resolution mass spectrometry

scientific article published on 13 July 2015

Determination of ITPase activity by capillary electrophoresis

scientific article published on 01 June 2007

Dr Jekyll and Mr Hyde: a strange case of 5-ethynyl-2'-deoxyuridine and 5-ethynyl-2'-deoxycytidine

scientific article published on January 2016

Fenretinide prevents inflammation and airway hyperresponsiveness in a mouse model of allergic asthma.

scientific article

Flow injection analysis vs. ultra high performance liquid chromatography coupled with tandem mass spectrometry for determination of imatinib in human plasma.

scientific article published on 13 August 2010

High lapatinib plasma levels in breast cancer patients: risk or benefit?

scientific article

High-throughput capillary electrophoretic method for determination of total aminothiols in plasma and urine.

scientific article

ITPase activity in dry blood spots is comparable with that in fresh erythrocytes.

scientific article published in June 2008

Imatinib dose escalation in two patients with chronic myeloid leukemia, with low trough imatinib plasma levels measured at various intervals from the beginning of therapy and with suboptimal treatment response, leads to the achievement of higher pla

scientific article published in May 2010

Imatinib trough plasma levels do not correlate with the response to therapy in patients with chronic myeloid leukemia in routine clinical setting

scientific article published on 11 January 2012

Isotope dilution direct injection mass spectrometry method for determination of four tyrosine kinase inhibitors in human plasma.

scientific article

Lipidomic profiling of human serum enables detection of pancreatic cancer

scientific article published on 10 January 2022

Mass spectrometric analysis of purine de novo biosynthesis intermediates

scientific article published in PLoS ONE

Mass spectrometry for analysis of purine and pyrimidine compounds

scientific article published on 01 January 2000

Metabolic status of CSF distinguishes rats with tauopathy from controls.

scientific article published on 21 September 2017

Metabolite Profiling of the Plasma and Leukocytes of Chronic Myeloid Leukemia Patients

scientific article published on 28 July 2016

Novel sulphur-containing imatinib metabolites found by untargeted LC-HRMS analysis.

scientific article published on 19 April 2017

Oligodendroglia from ADSL-deficient patient produce SAICAribotide and SAMP.

scientific article published on 25 June 2010

Oxidized phosphatidylcholines suggest oxidative stress in patients with medium-chain acyl-CoA dehydrogenase deficiency.

scientific article

Radio-sensitizing effects of VE-821 and beyond: Distinct phosphoproteomic and metabolomic changes after ATR inhibition in irradiated MOLT-4 cells

scientific article published on 12 July 2018

Screening method for inherited disorders of purine and pyrimidine metabolism by capillary electrophoresis with reversed electroosmotic flow

scientific article published in February 2002

Structural elucidation of novel biomarkers of known metabolic disorders based on multistage fragmentation mass spectra.

scientific article

Synthesis and mass spectrometric fragmentation characteristics of imidazole ribosides-analogs of intermediates of purine de novo synthetic pathway.

scientific article published in January 2006

TLR 7/8 Ligand, S28463, Suppresses Ascaris Suum Induced Allergic Asthma in Nonhuman Primates

scientific article published on 29 August 2017

Targeted metabolomic analysis of plasma samples for the diagnosis of inherited metabolic disorders

scientific article published on 04 October 2011

Ultrafast Online SPE-MS/MS Method for Quantification of 3 Tyrosine Kinase Inhibitors in Human Plasma.

scientific article published in August 2016

Untargeted metabolomic analysis of urine samples in the diagnosis of some inherited metabolic disorders.

scientific article published on 7 November 2014

Urease-immobilized magnetic microparticles in urine sample preparation for metabolomic analysis by gas chromatography-mass spectrometry

scientific article published on 10 July 2019

White Adipose Tissue Response of Obese Mice to Ambient Oxygen Restriction at Thermoneutrality: Response Markers Identified, but no WAT Inflammation.

scientific article published on 10 May 2019

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