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List of works by Giovanni Chillemi

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Massively parallel pyrosequencing highlights minority variants in the HIV-1 env quasispecies deriving from lymphomonocyte sub-populations

scientific article published on 12 February 2009
Single mutation in the linker domain confers protein flexibility and camptothecin resistance to human topoisomerase I.

scientific article
Antisense transcripts enhanced by camptothecin at divergent CpG-island promoters associated with bursts of topoisomerase I-DNA cleavage complex and R-loop formation

scientific article published on 2 September 2013
Identification of a short region on chromosome 6 affecting direct calving ease in Piedmontese cattle breed

scientific article
Massive screening of copy number population-scale variation in Bos taurus genome

scientific article (publication date: 26 February 2013)
Biallelic Mutations in TBCD, Encoding the Tubulin Folding Cofactor D, Perturb Microtubule Dynamics and Cause Early-Onset Encephalopathy

scientific journal article
Analysis of co-receptor usage of circulating viral and proviral HIV genome quasispecies by ultra-deep pyrosequencing in patients who are candidates for CCR5 antagonist treatment.

scientific article published on 5 November 2010
The p53 tetramer shows an induced-fit interaction of the C-terminal domain with the DNA-binding domain

scientific article published on 19 October 2015
Protein concerted motions in the DNA-human topoisomerase I complex.

scientific article
Revised Ionic Radii of Lanthanoid(III) Ions in Aqueous Solution

scientific article published on 15 April 2011
Valproic acid induces neuroendocrine differentiation and UGT2B7 up-regulation in human prostate carcinoma cell line

scientific article published on 19 March 2007
Global transcription regulation by DNA topoisomerase I in exponentially growing Saccharomyces cerevisiae cells: activation of telomere-proximal genes by TOP1 deletion

scientific article
Structure and hydration of the DNA-human topoisomerase I covalent complex.

scientific article
Structural and dynamical effects induced by the anticancer drug topotecan on the human topoisomerase I - DNA complex

scientific article
RNA-Sequencing for profiling goat milk transcriptome in colostrum and mature milk

scientific article
Evidence of the crucial role of the linker domain on the catalytic activity of human topoisomerase I by experimental and simulative characterization of the Lys681Ala mutant.

scientific article published on 18 September 2009
Effects of the pathological Q212P mutation on human prion protein non-octarepeat copper-binding site

scientific article published on 27 July 2012
Molecular dynamics of the full-length p53 monomer

scientific article published on September 5, 2013
Type I DNA Topoisomerases

scientific article published on 10 January 2017
Hydrogen and Higher Shell Contributions in Zn2+, Ni2+, and Co2+Aqueous Solutions: An X-ray Absorption Fine Structure and Molecular Dynamics Study

scientific article published on 01 March 2002
UV-vis spectra of the anticancer camptothecin family drugs in aqueous solution: specific spectroscopic signatures unraveled by a combined computational and experimental study

scientific article
A single mutation in the 729 residue modulates human DNA topoisomerase IB DNA binding and drug resistance.

scientific article published on 4 September 2008
New hints on the Ph-driven tautomeric equilibria of the topotecan anticancer drug in aqueous solutions from an integrated spectroscopic and quantum-mechanical approach

scientific article published in November 2005
Effects of dutasteride on the expression of genes related to androgen metabolism and related pathway in human prostate cancer cell lines.

scientific article
Signatures of selection in five Italian cattle breeds detected by a 54K SNP panel.

scientific article published on 19 January 2014
Microarrays and high-throughput transcriptomic analysis in species with incomplete availability of genomic sequences.

scientific article published on 05 April 2009
Hif1α down-regulation is associated with transposition of great arteries in mice treated with a retinoic acid antagonist

scientific article
Development and validation of an integrated computational approach for the study of ionic species in solution by means of effective two-body potentials. The case of Zn2+, Ni2+, and Co2+ in aqueous solutions.

scientific article published in March 2002
Role of the linker domain and the 203-214 N-terminal residues in the human topoisomerase I DNA complex dynamics.

scientific article published on 3 September 2004
Structural Evolution and Dynamics of the p53 Proteins.

scientific article published on 18 April 2016
Structural dynamics of the mitochondrial ADP/ATP carrier revealed by molecular dynamics simulation studies

scientific article
Erybraedin C, a natural compound from the plant Bituminaria bituminosa, inhibits both the cleavage and religation activities of human topoisomerase I.

scientific article published on 15 January 2010
Structural and dynamical properties of the Hg2+ aqua ion: a molecular dynamics study

scientific article published on 27 March 2008
Simulations of DNA topoisomerase 1B bound to supercoiled DNA reveal changes in the flexibility pattern of the enzyme and a secondary protein-DNA binding site

scientific article
Evidence for sevenfold coordination in the first solvation shell of Hg(II) aqua ion.

scientific article published on 6 April 2007
Archived HIV-1 minority variants detected by ultra-deep pyrosequencing in provirus may be fully replication competent

scientific article published in November 2009
Genome assembly and transcriptome resource for river buffalo, Bubalus bubalis (2n = 50).

scientific article published in September 2017
Molecular Characterization of the First Ebola Virus Isolated in Italy, from a Health Care Worker Repatriated from Sierra Leone

scientific article published on 18 June 2015
Novel and known genetic variants for male breast cancer risk at 8q24.21, 9p21.3, 11q13.3 and 14q24.1: results from a multicenter study in Italy

scientific article published on 3 August 2015
Whole-exome sequencing and targeted gene sequencing provide insights into the role of PALB2 as a male breast cancer susceptibility gene.

scientific article published on 20 September 2016
Dynamic changes in gene expression profiles of 22q11 and related orthologous genes during mouse development

scientific article published on 19 January 2007
CoVaCS: a consensus variant calling system

scientific article
Transcriptomic investigation of meat tenderness in two Italian cattle breeds.

scientific article published on 9 February 2016
The different cleavage DNA sequence specificity explains the camptothecin resistance of the human topoisomerase I Glu418Lys mutant.

scientific article
Modeling conformational transitions in kinases by molecular dynamics simulations: achievements, difficulties, and open challenges

scientific article published on 13 May 2014
Deciphering the structural properties that confer stability to a DNA nanocage.

scientific article
Importance of V3 Loop Flexibility and Net Charge in the Context of Co-Receptor Recognition. A Molecular Dynamics Study on HIV gp120

scientific article published on 01 January 2012
Microcephaly, intractable seizures and developmental delay caused by biallelic variants in TBCD: further delineation of a new chaperone-mediated tubulinopathy.

scientific article published on 2 November 2016
Assembly and characterization of pandemic influenza A H1N1 genome in nasopharyngeal swabs using high-throughput pyrosequencing.

scientific article
Dynamic Investigation of Protein Metal Active Sites: Interplay of XANES and Molecular Dynamics Simulations

scientific article published on 01 October 2010

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