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List of works by Sophie Erhardt

A role for inflammatory metabolites as modulators of the glutamate N-methyl-D-aspartate receptor in depression and suicidality

scientific article published on 12 August 2014

Activation of brain interleukin-1beta in schizophrenia.

scientific article published on December 2009

Activation of nigral dopamine neurons by the selective GABA(B)-receptor antagonist SCH 50911.

scientific article

Activation of noradrenergic locus coeruleus neurons by clozapine and haloperidol: involvement of glutamatergic mechanisms

scientific article published on 18 February 2005

Activation of rat ventral tegmental area dopamine neurons by endogenous kynurenic acid: a pharmacological analysis

scientific article published on 20 September 2007

Acyclovir inhibition of IDO to decrease Tregs as a glioblastoma treatment adjunct.

scientific article published on 6 August 2010

Altered chemokine levels in the cerebrospinal fluid and plasma of suicide attempters

scientific article published on 9 October 2012

Behavioral disturbances in adult mice following neonatal virus infection or kynurenine treatment--role of brain kynurenic acid

scientific article

CSF biomarkers in suicide attempters--a principal component analysis.

scientific article

CSF kynurenic acid and suicide risk in schizophrenia spectrum psychosis

scientific article

Cerebrospinal fluid concentration of complement component 4A is increased in first episode schizophrenia

scientific article published in 2022

Cerebrospinal fluid kynurenic acid in male and female controls - correlation with monoamine metabolites and influences of confounding factors

scientific article published on 24 January 2006

Cerebrospinal fluid kynurenic acid in male patients with schizophrenia – correlation with monoamine metabolites

scientific article published on 01 February 2007

Cerebrospinal fluid kynurenic acid is associated with manic and psychotic features in patients with bipolar I disorder

scientific article published on 3 October 2012

Clozapine interacts with the glycine site of the NMDA receptor: electrophysiological studies of dopamine neurons in the rat ventral tegmental area

scientific article published on 10 June 2008

Clozapine modulates midbrain dopamine neuron firing via interaction with the NMDA receptor complex

scientific article published in May 2004

Connecting inflammation with glutamate agonism in suicidality.

scientific article published on 3 December 2012

Effects of COX-1 and COX-2 inhibitors on the firing of rat midbrain dopaminergic neurons--possible involvement of endogenous kynurenic acid

scientific article published in April 2006

Elevated levels of kynurenic acid change the dopaminergic response to amphetamine: implications for schizophrenia

scientific article

Elevated levels of kynurenic acid in the cerebrospinal fluid of male patients with schizophrenia

scientific article published on 25 August 2005

Elevated levels of kynurenic acid in the cerebrospinal fluid of patients with bipolar disorder

scientific article

Endogenous kynurenic acid disrupts prepulse inhibition

scientific article

Excitation of nigral dopamine neurons by the GABA(A) receptor agonist muscimol is mediated via release of glutamate

scientific article published on 01 September 2000

Excitatory and inhibitory responses of dopamine neurons in the ventral tegmental area to nicotine.

scientific article published on March 2002

GABA(B) receptor-mediated modulation of the firing pattern of ventral tegmental area dopamine neurons in vivo

scientific article published on 6 February 2002

Imbalanced kynurenine pathway in schizophrenia

scientific article published on 16 September 2014

Increased levels of IL-6 in the cerebrospinal fluid of patients with chronic schizophrenia--significance for activation of the kynurenine pathway.

scientific article

Increased levels of kynurenine and kynurenic acid in the CSF of patients with schizophrenia.

scientific article published on 20 August 2010

Increased peripheral levels of TARC/CCL17 in first episode psychosis patients

scientific article published on 03 January 2019

Increased phasic activity of dopaminergic neurones in the rat ventral tegmental area following pharmacologically elevated levels of endogenous kynurenic acid

scientific article published in May 2002

Inhibition of firing rate and changes in the firing pattern of nigral dopamine neurons by gamma-hydroxybutyric acid (GHBA) are specifically induced by activation of GABA(B) receptors

scientific article

Inhibitory action of clozapine on rat ventral tegmental area dopamine neurons following increased levels of endogenous kynurenic acid

scientific article

Interleukin-6 is elevated in the cerebrospinal fluid of suicide attempters and related to symptom severity.

scientific article published on 6 March 2009

Kynurenic Acid levels in cerebrospinal fluid from patients with Alzheimer's disease or dementia with lewy bodies

scientific article

Kynurenic acid levels are elevated in the cerebrospinal fluid of patients with schizophrenia

scientific article published in November 2001

Kynurenine 3-monooxygenase (KMO) polymorphisms in schizophrenia: An association study

Kynurenine 3-monooxygenase polymorphisms: relevance for kynurenic acid synthesis in patients with schizophrenia and healthy controls

scientific article

Lipopolysaccharide Increases Cortical Kynurenic Acid and Deficits in Reference Memory in Mice

scientific article published on 17 December 2019

Neonatal infection with neurotropic influenza A virus induces the kynurenine pathway in early life and disrupts sensorimotor gating in adult Tap1-/- mice

scientific article

Nicotine-induced excitation of locus coeruleus neurons is blocked by elevated levels of endogenous kynurenic acid

scientific article published on 01 August 2000

Oxytocin increases locus coeruleus alpha 2-adrenoreceptor responsiveness in rats

scientific article published in October 1998

Pharmacological elevation of endogenous kynurenic acid levels activates nigral dopamine neurons

scientific article published in January 2001

Pharmacological manipulation of kynurenic acid: potential in the treatment of psychiatric disorders

scientific article published on January 2009

Prenatal dexamethasone impairs behavior and the activation of the BDNF exon IV promoter in the paraventricular nucleus in adult offspring

scientific article published on 28 August 2008

Quantification of Plasma Kynurenine Metabolites Following One Bout of Sprint Interval Exercise

scientific article published on 10 December 2020

Repeated LPS Injection Induces Distinct Changes in the Kynurenine Pathway in Mice.

scientific article

Role of the NMDA-receptor in Prepulse Inhibition in the Rat ⬇️

scientific article published on February 12, 2010

Skeletal muscle PGC-1α1 modulates kynurenine metabolism and mediates resilience to stress-induced depression

scientific article

Subchronic elevation of brain kynurenic acid augments amphetamine-induced locomotor response in mice.

scientific article published on 9 September 2011

Subchronic treatment with kynurenine and probenecid: effects on prepulse inhibition and firing of midbrain dopamine neurons

scientific article published on 5 August 2005

The KMO allele encoding Arg452 is associated with psychotic features in bipolar disorder type 1, and with increased CSF KYNA level and reduced KMO expression

scientific article published on 05 March 2013

The anaesthetic agent propofol interacts with GABA(B)-receptors: an electrophysiological study in rat.

scientific article published in May 2003

The kynurenic acid hypothesis of schizophrenia

scientific article

The kynurenine pathway in schizophrenia and bipolar disorder.

scientific article published on 28 May 2016

Twin study shows association between monocyte chemoattractant protein-1 and kynurenic acid in cerebrospinal fluid

scientific article published on 13 July 2019

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