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List of works by Espen Molden

4β-Hydroxycholesterol Level in Patients With Rheumatoid Arthritis Before vs. After Initiation of bDMARDs and Correlation With Inflammatory State

scientific article

4β-Hydroxycholesterol level significantly correlates with steady-state serum concentration of the CYP3A4 substrate quetiapine in psychiatric patients

scientific article published on 5 June 2017

4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation?

scientific article published on 17 November 2015

Adipokine levels are associated with insulin resistance in antipsychotics users independently of BMI

scientific article published on 06 January 2019

Age Impacts Olanzapine Exposure Differently During Use of Oral Versus Long-Acting Injectable Formulations: An Observational Study Including 8,288 Patients

article

Association of CYP2C19 and CYP2D6 Poor and Intermediate Metabolizer Status With Antidepressant and Antipsychotic Exposure: A Systematic Review and Meta-analysis

scientific article published on 25 November 2020

Associations between Cytokine Levels and CYP3A4 Phenotype in Patients with Rheumatoid Arthritis

scientific article published on 10 July 2018

Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance.

scientific article published on 22 December 2016

CYP2C19 genetics in fatal carisoprodol intoxications ⬇️

scientific article published on April 15, 2012

CYP2D6 is involved in O-demethylation of diltiazem. An in vitro study with transfected human liver cells

scientific article published on 01 November 2000

Changes in drug disposition of lithium during pregnancy: a retrospective observational study of patient data from two routine therapeutic drug monitoring services in Norway

scientific article

Clinically Relevant Effect of UGT1A4*3 on Lamotrigine Serum Concentration Is Restricted to Postmenopausal Women-A Study Matching Therapeutic Drug Monitoring and Genotype Data From 534 Patients

scientific article published on 01 October 2018

Clozapine ultrarapid metabolism during weak induction probably exists but requires careful diagnosis. A literature review, five new cases and a proposed definition

scientific article published in 2023

Combined Effect of CYP2B6 Genotype and Other Candidate Genes on a Steady-State Serum Concentration of Methadone in Opioid Maintenance Treatment

scientific article published on 18 July 2017

Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection.

scientific article published on 26 February 2018

Comparison of CYP3A4-Inducing Capacity of Enzyme-Inducing Antiepileptic Drugs Using 4β-Hydroxycholesterol as Biomarker

scientific article published on 01 August 2018

Correction: Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits

scientific article published on 02 November 2020

Correction: Selective serotonin reuptake inhibitors and venlafaxine in pregnancy: Changes in drug disposition

scientific article

Correlation Between Serum Concentrations of N-Desmethylclozapine and Granulocyte Levels in Patients with Schizophrenia: A Retrospective Observational Study

scientific article

Desacetyl-Diltiazem Displays Severalfold Higher Affinity to CYP2D6 Compared with CYP3A4 ⬇️

scientific article published on January 1, 2002

Effect of CYP2B6*6 on Steady-State Serum Concentrations of Bupropion and Hydroxybupropion in Psychiatric Patients: A Study Based on Therapeutic Drug Monitoring Data

scientific article

Effect of CYP2D6 genotype on exposure and efficacy of risperidone and aripiprazole: a retrospective, cohort study

scientific article published on 15 April 2019

Effect of Grapefruit Juice Intake on Serum Level of the Endogenous CYP3A4 Metabolite 4β-Hydroxycholesterol-an Interaction Study in Healthy Volunteers

scientific article published on 24 April 2019

Elevated 4β-hydroxycholesterol/cholesterol ratio in anorexia nervosa patients

scholarly article by Kristine Hole et al published October 2018 in Pharmacology research & perspectives

Evaluation of microsomal incubation conditions on CYP3A4-mediated metabolism of cyclosporine A by a statistical experimental design

scientific article published on 01 April 2006

Evaluation of organic anion-transporting polypeptide 1B1 and CYP3A4 activities in primary human hepatocytes and HepaRG cells cultured in a dynamic three-dimensional bioreactor system

scientific article published on 12 July 2012

Exploring low clozapine C/D ratios, inverted clozapine-norclozapine ratios and undetectable concentrations as measures of non-adherence in clozapine patients

scientific article published in 2023

Exposure of atorvastatin is unchanged but lactone and acid metabolites are increased several-fold in patients with atorvastatin-induced myopathy

scientific article

Extensive metabolism of diltiazem and P-glycoprotein-mediated efflux of desacetyl-diltiazem (M1) by rat jejunum in vitro.

scientific article published in February 2000

Fatal liver failure after therapeutic doses of paracetamol in a patient with Duchenne muscular dystrophy and atypical pharmacogenetic profile of drug-metabolizing enzymes

scientific article published on 24 January 2020

Free thyroxine and thyroid-stimulating hormone in severe mental disorders: A naturalistic study with focus on antipsychotic medication

scientific article published on 25 September 2018

Gjestad et al. reply to 'Was 4β-hydroxycholesterol ever going to be a useful marker of CYP3A4 activity?' by Neuhoff and Tucker

scientific article published on 10 May 2018

Heterozygous mutation in CYP2C19 significantly increases the concentration/dose ratio of racemic citalopram and escitalopram (S-citalopram).

scientific article published in February 2006

High-performance liquid chromatography-mass spectrometry analysis of diltiazem and 11 of its phase I metabolites in human plasma

scientific article

Hvis du skal gjøre det, gjør det riktig!

scientific article published on 26 June 2017

Identification of a novel CYP2C19-mediated metabolic pathway of S-citalopram in vitro

scientific article published on 22 September 2009

Identification of a novel polymorphism associated with reduced clozapine concentration in schizophrenia patients-a genome-wide association study adjusting for smoking habits

scientific article published on 19 June 2020

Identification of epoxybergamottin as a CYP3A4 inhibitor in grapefruit peel

scientific article

Impact of Ageing on Serum Concentrations of Risperidone and Its Active Metabolite in Patients with Known CYP2D6 Genotype

scientific article published on 4 May 2016

Impact of CYP2C19 Genotype on Escitalopram Exposure and Therapeutic Failure: A Retrospective Study Based on 2,087 Patients

scientific article published on 12 January 2018

Impact of CYP2C19 genotype on sertraline exposure in 1200 Scandinavian patients

scientific article published on 24 October 2019

Impact of CYP2D6 genotype on steady-state serum concentrations of risperidone and 9-hydroxyrisperidone in patients using long-acting injectable risperidone

scientific article published in December 2009

Impact of OATP1B1, MDR1, and CYP3A4 Expression in Liver and Intestine on Interpatient Pharmacokinetic Variability of Atorvastatin in Obese Subjects

scientific article published on December 27, 2012

Impact of age and CYP2D6 genetics on exposure of aripiprazole and dehydroaripiprazole in patients using long-acting injectable versus oral formulation: relevance of poor and intermediate metabolizer status

scientific article published on 21 October 2019

Impact of age and CYP2D6 genotype on exposure of zuclopenthixol in patients using long-acting injectable versus oral formulation-an observational study including 2044 patients

scientific article published on 30 September 2020

Impact of age on serum concentrations of venlafaxine and escitalopram in different CYP2D6 and CYP2C19 genotype subgroups

scientific article published on 27 May 2014

Impact of age, gender and CYP2C9/2C19 genotypes on dose-adjusted steady-state serum concentrations of valproic acid-a large-scale study based on naturalistic therapeutic drug monitoring data

scientific article

Impact of antipsychotic polypharmacy on nonadherence of oral antipsychotic drugs - A study based on blood sample analyses from 24,239 patients

scientific article published on 25 June 2020

Impact of genetic and nongenetic factors on interindividual variability in 4β-hydroxycholesterol concentration

scientific article published on 14 December 2016

Impact of genetic variability in CYP2D6, CYP3A5, and ABCB1 on serum concentrations of quetiapine and N-desalkylquetiapine in psychiatric patients

scientific article published in April 2015

Impact of genotype-predicted CYP2D6 metabolism on clinical effects and tolerability of metoprolol in patients after myocardial infarction - a prospective observational study

scientific article published on 15 January 2020

Impact of the CYP2D6 genotype on steady-state serum concentrations of aripiprazole and dehydroaripiprazole

scientific article published on 09 September 2007

Impact of the ultrarapid CYP2C19*17 allele on serum concentration of escitalopram in psychiatric patients

scientific article published on 11 July 2007

Impairment of endoxifen formation in tamoxifen-treated premenopausal breast cancer patients carrying reduced-function CYP2D6 alleles

scientific article published on 26 July 2020

Individual variability in clinical effect and tolerability of opioid analgesics - Importance of drug interactions and pharmacogenetics

scientific article published on 17 October 2017

Influence of CYP1A1/CYP1A2 and AHR polymorphisms on systemic olanzapine exposure ⬇️

scientific article published on May 1, 2013

Interactions between metoprolol and antidepressants ⬇️

scientific article published on September 20, 2011

Mapping genomic loci implicates genes and synaptic biology in schizophrenia

scientific article published on 8 April 2022

Metabolism of quetiapine by CYP3A4 and CYP3A5 in presence or absence of cytochrome B5.

scientific article published on 20 November 2008

Metabolism of the Active Metabolite of Quetiapine,N-Desalkylquetiapine In Vitro ⬇️

scientific article published on June 11, 2012

More potent lipid-lowering effect by rosuvastatin compared with fluvastatin in everolimus-treated renal transplant recipients

scientific article

No influence of CYP3A43 rs472660G> A on steady-state serum olanzapine concentrations in white psychiatric patients

scientific article published on May 2014

OATP1B1/1B3 activity in plated primary human hepatocytes over time in culture

scientific article published on 20 July 2011

Pharmacokinetic Variability of Quetiapine and the Active Metabolite N-desalkylquetiapine in Psychiatric Patients ⬇️

scientific article published on April 1, 2011

Pharmacokinetic interactions between microemulsion formulated cyclosporine A and diltiazem in renal transplant recipients

scientific article published on 01 July 1999

Pharmacokinetic variability of aripiprazole and the active metabolite dehydroaripiprazole in psychiatric patients

scientific article published in December 2006

Pharmacokinetics of diltiazem and its metabolites in relation to CYP2D6 genotype

scientific article published in September 2002

Psychotropics and weak opioid analgesics in plasma samples of older hip fracture patients - detection frequencies and consistency with drug records

scientific article

Publisher Correction: Common schizophrenia alleles are enriched in mutation-intolerant genes and in regions under strong background selection

scientific article published on 01 July 2019

Rates of complete nonadherence among atypical antipsychotic drugs: A study using blood samples from 13,217 outpatients with psychotic disorders

scientific article published on 18 November 2020

Recovery of CYP3A Phenotype after Kidney Transplantation

scientific article published on 19 September 2017

Reduction in N-Desmethylclozapine Level Is Determined by Daily Dose But Not Serum Concentration of Valproic Acid-Indications of a Presystemic Interaction Mechanism

scientific article published on 01 August 2019

Response to: 'Response to: Bodyweight-adjustments introduce significant correlations between CYP3A metrics and tacrolimus clearance'.

scientific article published on 3 April 2017

Response: Are thyroid abnormalities only related to antipsychotic treatment in patients with severe mental disorders?

scientific article published on 13 November 2018

Risperidone and Venlafaxine Metabolic Ratios Strongly Predict a CYP2D6 Poor Metabolizing Genotype

scientific article published on 01 February 2016

Safer treatment with serum concentration monitoring of the new anticoagulants?

scientific article published on 11 October 2016

Selective serotonin reuptake inhibitors and venlafaxine in pregnancy: Changes in drug disposition

scientific article published on 14 July 2017

Serum Concentrations and Elimination Rates of Direct-Acting Oral Anticoagulants (DOACs) in Older Hip Fracture Patients Hospitalized for Surgery: A Pilot Study

scientific article published on 01 January 2019

Serum Concentrations of Antidepressants in The Elderly ⬇️

scientific article published on February 1, 2012

Serum concentrations of risperidone and aripiprazole in subgroups encoding CYP2D6 intermediate metabolizer phenotype

scientific article published in February 2014

Serum concentrations of sertraline and N-desmethyl sertraline in relation to CYP2C19 genotype in psychiatric patients

scientific article

Serumkonsentrasjonsmålinger av DOAK-legemidler

scientific article published on 17 April 2018

Sex-Dependent Shared and Nonshared Genetic Architecture Across Mood and Psychotic Disorders

scientific article

Side effect burden of antipsychotic drugs in real life - Impact of gender and polypharmacy

scientific article published on 6 November 2017

Significantly lower CYP2D6 metabolism measured as the O/N-desmethylvenlafaxine metabolic ratio in carriers of CYP2D6*41 versus CYP2D6*9 or CYP2D6*10 - A study on therapeutic drug monitoring data from 1,003 genotyped Scandinavian patients

scientific article published on 11 November 2018

Substantial Differences in Serum Concentrations of Psychoactive Drugs Measured in Samples Stored for 2 Days or More on Standard Serum Tubes Versus Serum Tubes Containing Gel Separators

scientific article published on 01 June 2019

T229. ANTIPSYCHOTIC DRUG USE AND THYROID FUNCTION IN PATIENTS WITH SEVERE MENTAL DISORDERS.

scientific article published in April 2018

The CYP3A biomarker 4β-hydroxycholesterol does not improve tacrolimus dose predictions early after kidney transplantation.

scientific article

The Effect of Coadministration of Duloxetine on Steady-State Serum Concentration of Risperidone and Aripiprazole: A Study Based on Therapeutic Drug Monitoring Data ⬇️

scientific article published on December 1, 2010

The Effect of Valproic Acid on Olanzapine Serum Concentration: A Study Including 2791 Patients Treated With Olanzapine Tablets or Long-Acting Injections

scientific article published on 01 November 2019

The Influence of Combined CYP2D6 and CYP2C19 Genotypes on Venlafaxine and O-Desmethylvenlafaxine Concentrations in a Large Patient Cohort

scientific article published on 01 March 2020

The complexity of active metabolites in therapeutic drug monitoring of psychotropic drugs

scientific article published on July 2006

The effect of ethinylestradiol‐containing contraceptives on the serum concentration of olanzapine and N‐desmethyl olanzapine ⬇️

scientific article published on April 1, 2011

The effect of variable cigarette consumption on the interaction with clozapine and olanzapine

scientific article published on 07 November 2006

Therapeutic Drug Monitoring of Selective Serotonin Reuptake Inhibitors in Elderly Patients

scientific article published on August 2015

Tobacco smoking and drug interactions

scientific article

Treatment with antipsychotics in pregnancy: Changes in drug disposition

scientific article published on 23 June 2017

UGT1A4*3 encodes significantly increased glucuronidation of olanzapine in patients on maintenance treatment and in recombinant systems

scientific article published on 20 June 2012

Undetectable or subtherapeutic serum levels of antipsychotic drugs preceding switch to clozapine

scientific article published on 17 July 2020

Use of Antidepressants in Older People during a 10-Year Period: An Observational Study on Prescribed Doses and Serum Levels

scientific article published on 20 July 2020

Valproic Acid significantly lowers serum concentrations of olanzapine-an interaction effect comparable with smoking

scientific article published in October 2012

[Cytochrome P-450 3A4--the most important arena for drug interactions in the body]

scientific article published on 01 December 2008

[Fruit and berries--interactions with drugs]

scientific article published on 01 December 2007

[Genetically determined variation in bioactivation of tamoxifen and clopidogrel]

scientific article published on 15 March 2016

[Rather common, but not indefensible].

scientific article published in April 2009

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