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List of works by François Paquet-Durand

A key role for cyclic nucleotide gated (CNG) channels in cGMP-related retinitis pigmentosa.

scientific article published on 10 December 2010

A retinal model of cerebral malaria

scientific article published on 05 March 2019

CNTF+BDNF treatment and neuroprotective pathways in the rd1 mouse retina

scientific article published on 6 December 2006

Calcium dynamics change in degenerating cone photoreceptors

scientific article published on 8 July 2016

Calpain activity in retinal degeneration.

scientific article published on March 2007

Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats

scientific article

Calpain is activated in degenerating photoreceptors in the rd1 mouse

scientific article published on 9 January 2006

Calpain-mediated ataxin-3 cleavage in the molecular pathogenesis of spinocerebellar ataxia type 3 (SCA3).

scientific article

Cav1.4 L-Type Calcium Channels Contribute to Calpain Activation in Degenerating Photoreceptors of rd1 Mice

scientific article

Cell death of spinal cord ED1(+) cells in a rat model of multiple sclerosis.

scientific article

Cellular phenotypes of human model neurons (NT2) after differentiation in aggregate culture

scientific article published on 18 April 2009

Characterization of a mouse model with complete RPE loss and its use for RPE cell transplantation

scientific article published on 7 August 2014

Combination of cGMP analogue and drug delivery system provides functional protection in hereditary retinal degeneration.

scientific article published on 12 March 2018

Current therapeutic approaches in inherited retinal degeneration: from genes to chip

scientific article published on 21 March 2014

DNA methylation and differential gene regulation in photoreceptor cell death

scientific article published on 4 December 2014

Differential modification of phosducin protein in degenerating rd1 retina is associated with constitutively active Ca2+/calmodulin kinase II in rod outer segments

scientific article

Diltiazem protects human NT-2 neurons against excitotoxic damage in a model of simulated ischemia.

scientific article published on 27 October 2006

Drug delivery to retinal photoreceptors

scientific article published on 13 March 2019

Efficacy of PARP inhibition in Pde6a mutant mouse models for retinitis pigmentosa depends on the quality and composition of individual human mutations.

scientific article published on 4 July 2016

Excessive Activation of Poly(ADP-Ribose) Polymerase Contributes to Inherited Photoreceptor Degeneration in the Retinal Degeneration 1 Mouse

scientific article published on 01 September 2007

Excessive HDAC activation is critical for neurodegeneration in the rd1 mouse.

scientific article

Expression of poly(ADP-ribose) glycohydrolase in wild-type and PARG-110 knock-out retina

scientific article published in January 2014

Gene therapy successfully delays degeneration in a mouse model of PDE6A-linked retinitis pigmentosa (RP 43).

scientific article published on 7 December 2017

HDAC inhibition prevents Rd1 mouse photoreceptor degeneration

scientific article published on 01 January 2012

Hypoxic/ischaemic cell damage in cultured human NT-2 neurons.

scientific article published on June 2004

Identification of a common non-apoptotic cell death mechanism in hereditary retinal degeneration

scientific article

Imaging Ca2+ dynamics in cone photoreceptor axon terminals of the mouse retina.

scientific article

In vivo assessment of rodent retinal structure using spectral domain optical coherence tomography

scientific article published on 01 January 2012

Inhibition of mitochondrial pyruvate transport by zaprinast causes massive accumulation of aspartate at the expense of glutamate in the retina

scientific article

Integrative Kinase Activity Profiling and Phosphoproteomics of rd10 Mouse Retina during cGMP-Dependent Retinal Degeneration

scientific article published in 2024

Knockout of PARG110 confers resistance to cGMP-induced toxicity in mammalian photoreceptors

scientific article published on 22 May 2014

Light-Driven Calcium Signals in Mouse Cone Photoreceptors

scientific article published on 01 May 2012

Neuroprotective Strategies for the Treatment of Inherited Photoreceptor Degeneration ⬇️

scientific article published on June 1, 2012

Novel in situ activity assays for the quantitative molecular analysis of neurodegenerative processes in the retina

scientific article

Olaparib significantly delays photoreceptor loss in a model for hereditary retinal degeneration

scientific article published on 22 December 2016

Organotypic retinal explant cultures as in vitro alternative for diabetic retinopathy studies.

scientific article published on 9 May 2016

PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.

scientific article

PKG activity causes photoreceptor cell death in two retinitis pigmentosa models

scientific article published in February 2009

PKG-Dependent Cell Death in 661W Cone Photoreceptor-like Cell Cultures (Experimental Study).

scientific article

Photoreceptor cell death mechanisms in inherited retinal degeneration.

scientific article

Photoreceptor rescue and toxicity induced by different calpain inhibitors.

scientific article published on 28 September 2010

Primary Rod and Cone Degeneration Is Prevented by HDAC Inhibition

scientific article published on 01 January 2018

Retinitis Pigmentosa: over-expression of anti-ageing protein Klotho in degenerating photoreceptors

scientific article published on 22 July 2013

Retinitis pigmentosa: impact of different Pde6a point mutations on the disease phenotype.

scientific article published on 17 July 2015

Spectral domain optical coherence tomography in mouse models of retinal degeneration.

scientific article published on 6 August 2009

Study of gene-targeted mouse models of splicing factor gene Prpf31 implicated in human autosomal dominant retinitis pigmentosa (RP).

scientific article

Targeted ablation of the Pde6h gene in mice reveals cross-species differences in cone and rod phototransduction protein isoform inventory.

scientific article

Targeting connexin hemichannels to control the inflammasome: the correlation between connexin43 and NLRP3 expression in chronic eye disease

scientific article published on 11 October 2019

Temporal progression of PARP activity in the Prph2 mutant rd2 mouse: Neuroprotective effects of the PARP inhibitor PJ34.

scientific article

Turning teratocarcinoma cells into neurons: rapid differentiation of NT-2 cells in floating spheres

scientific article published in May 2003

Up-regulation and increased phosphorylation of protein kinase C (PKC) delta, mu and theta in the degenerating rd1 mouse retina

scientific article published on 28 February 2006

Visualizing Cell Death in Live Retina: Using Calpain Activity Detection as a Biomarker for Retinal Degeneration

scientific article published on 31 March 2022

cGMP-Prkg1 signaling PDE5 inhibition shelter cochlear hair cells and hearing function

scientific article published on 29 August 2013

cGMP-Prkg1 signaling and Pde5 inhibition shelter cochlear hair cells and hearing function

scientific article published on 22 January 2012

cGMP-dependent cone photoreceptor degeneration in the cpfl1 mouse retina.

scientific article published in September 2010

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