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List of works by Robert J. Simpson

2, 4-diamino-6- hydroxy pyrimidine inhibits NSAIDs induced nitrosyl-complex EPR signals and ulcer in rat jejunum

scientific article

A nano-disperse ferritin-core mimetic that efficiently corrects anemia without luminal iron redox activity ⬇️

scientific article

A study of the effects of indometacin on liver mitochondria from rats, mice and humans

scientific article published in November 2001

An iron-regulated ferric reductase associated with the absorption of dietary iron

scientific article (publication date: 2 March 2001)

Application of selective extraction to the study of iron species present in diet and rat gastrointestinal tract contents

scientific article published on 01 May 1992

BMPER protein is a negative regulator of hepcidin and is up-regulated in hypotransferrinemic mice.

scientific article published on 5 December 2011

COX-1, COX-2 and the topical effect in NSAID-induced enteropathy

scientific article published on 01 January 2003

Characterization of the transition-metal-binding properties of hepcidin

scientific journal article

Comparison of indomethacin and nimesulide, a selective cyclooxygenase-2 inhibitor, on key pathophysiologic steps in the pathogenesis of nonsteroidal anti-inflammatory drug enteropathy in the rat

scientific article published on 01 July 1998

Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro.

scientific article

Duodenal cytochrome b (Cybrd 1) and HIF-2α expression during acute hypoxic exposure in mice.

scientific article published on 27 February 2011

Duodenal mucosal reductase in wild-type and Hfe knockout mice on iron adequate, iron deficient, and iron rich feeding.

scientific article published in April 2003

Duodenal nonheme iron content correlates with iron stores in mice, but the relationship is altered by Hfe gene knock-out

scientific article published on 05 December 2002

Duodenal reductase activity and spleen iron stores are reduced and erythropoiesis is abnormal in Dcytb knockout mice exposed to hypoxic conditions

scientific article

Effect of Tin-mesoporphyrin, an inhibitor of haem catabolism, on intestinal iron absorption

scientific article published in July 2003

Effect of altered iron metabolism on markers of haem biosynthesis and intestinal iron absorption in mice

scientific article published on 15 September 2004

Effect of hepcidin on intestinal iron absorption in mice.

scientific article published on 29 January 2004

Effect of hypoxic exposure on iron absorption in heterozygous hypotransferrinaemic mice

scientific article published on 01 December 1992

Effect of transition metal ions (cobalt and nickel chlorides) on intestinal iron absorption

scientific article published in September 2004

Effects of acute and chronic inflammation on proteins involved in duodenal iron absorption in mice: a time-course study

scientific article published on 24 February 2012

Effects of indomethacin on energy metabolism in rat and human jejunal tissue in vitro

scientific article published in November 2001

Effects of indomethacin on energy metabolism in rat jejunal tissue in vivo

scientific article published in May 2002

Expression of iron absorption genes in mouse large intestine

scientific article (publication date: February 2005)

Gastric acid secretion in cyclooxygenase-1 deficient mice

scientific article published in October 2000

Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1).

scientific article published on 10 September 2008

Hypoxic response of iron absorption is not affected by the Hfe gene knock-out in mice

scientific article

Immunolocalization of duodenal cytochrome B: a relationship with circulating markers of iron status

scientific article published on 01 December 2006

Impaired iron transport activity of ferroportin 1 in hereditary iron overload

scientific article

Intestinal iron absorption and mucosal transferrin in rats subjected to hypoxia

scientific article published on 01 November 1987

Iron absorption in hepcidin1 knockout mice

scientific article published on 08 February 2011

Iron absorption: biochemical and molecular insights into the importance of iron species for intestinal uptake.

scientific article

Iron and cadmium uptake by duodenum of hypotransferrinaemic mice

scientific article published on 01 October 2006

Iron binding to, and release from, the basolateral membrane of mouse duodenal enterocytes

scientific article published in May 1991

Iron metabolism in hepcidin1 knockout mice in response to phenylhydrazine-induced hemolysis

scientific article published on 19 May 2012

Iron proteins of duodenal enterocytes isolated from mice with genetically and experimentally altered iron metabolism

scientific article published on 01 June 1999

Long-term sequelae of HFE deletion in C57BL/6 x 129/O1a mice, an animal model for hereditary haemochromatosis

scientific article published on 01 August 2002

Nitric oxide: potential role for reducing gastro-enteropathy

scientific article published on 01 January 2003

Of mice and men: genetic determinants of iron status

scientific article

Quantification of hepcidin using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.

scientific article

Quantitation of hepcidin in human urine by liquid chromatography-mass spectrometry.

scientific article published on 5 October 2008

Regulation of intestinal iron absorption: the mucosa takes control?

scientific article published on August 2009

Regulation of iron metabolism in Hamp (-/-) mice in response to iron-deficient diet

scientific article published on 13 January 2012

Role of COX-2 in nonsteroidal anti-inflammatory drug enteropathy in rodents

scientific article published in August 2010

Role of bile in pathogenesis of indomethacin-induced enteropathy

scientific article published on 07 December 2006

Role of interleukin-6 in hypoxic regulation of intestinal iron absorption

scientific article published on 01 December 2005

Subcellular localization of recently-absorbed iron in mouse duodenal enterocytes: identification of a basolateral membrane iron-binding site

scientific article published on 01 April 1990

The effect of haem biosynthesis inhibitors and inducers on intestinal iron absorption and liver haem biosynthetic enzyme activities

scientific article published on 7 February 2008

The effects of AZD3582 [4-(nitroxy)butyl-(2S)-2-(6-methoxy-2-naphthyl) propanoate], and naproxen on key pathogenic steps in NSAID-enteropathy in the rat.

scientific article published in June 2007

The ferric-reducing activity of duodenal brush-border membrane vesicles is associated with a b-type haem

scientific article published on 01 March 1999

The hypotransferrinaemic mouse: ultrastructural and laser microprobe analysis observations.

scientific article published on September 1995

The transcription factor ATOH8 is regulated by erythropoietic activity and regulates HAMP transcription and cellular pSMAD1,5,8 levels

scientific article

Tissue iron loading and histopathological changes in hypotransferrinaemic mice

scientific article published on 01 November 1993

Tumour necrosis factor alpha causes hypoferraemia and reduced intestinal iron absorption in mice.

scientific article published on July 2006

Uptake of 26-Al and 67-Ga into brain and other tissues of normal and hypotransferrinaemic mice

scientific article published in July 1997

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