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List of works by Hiroki Oguri

A fully synthetic 6-aza-artemisinin bearing an amphiphilic chain generates aggregates and exhibits anti-cancer activities

scientific article published on 03 July 2020

Allosteric regulation of epoxide opening cascades by a pair of epoxide hydrolases in monensin biosynthesis

scientific article

An anti-tetraamination of a 1,3-diene unit via cascade annulations of the azulenone scaffold with dicarbonyl azo-compounds

scientific article published on 15 March 2010

Biogenetically inspired synthesis and skeletal diversification of indole alkaloids

scientific article published on 24 November 2013

Biomimetic Assembly Lines Producing Natural Product Analogs: Strategies from a Versatile Manifold to Skeletally Diverse Scaffolds

scientific article published on 01 February 2016

Bioorganic Studies Utilizing Rationally Designed Synthetic Molecules: Absolute Configuration of Ciguatoxin and Development of Immunoassay Systems

article

Biosynthetic machinery of ionophore polyether lasalocid: enzymatic construction of polyether skeleton.

scientific article published on 21 June 2013

Chemo-enzymatic Total Syntheses of Jorunnamycin A, Saframycin A, and N-Fmoc Saframycin Y3

scientific article published on 16 August 2018

Chiroptical Inversion of Europium(III) Complexes by Changing a Remote Stereogenic Center of a C2-Symmetric Bispyrrolidinoindoline Manifold

scientific article published on 12 December 2018

Complete sequence of biosynthetic gene cluster responsible for producing triostin A and evaluation of quinomycin-type antibiotics from Streptomyces triostinicus ⬇️

scientific article

Concise synthesis of ciguatoxin ABC-ring fragments and surface plasmon resonance study of the interaction of their BSA conjugates with monoclonal antibodies

scientific article published in August 2001

Construction of the benzylic quaternary carbon center of zoanthenol by intramolecular Mizoroki-Heck reaction of enone

scientific article published on 01 May 2002

Core assembly mechanism of quinocarcin/SF-1739: bimodular complex nonribosomal peptide synthetases for sequential mannich-type reactions

scientific article published on 21 November 2013

Critical contribution of aromatic rings to specific recognition of polyether rings. The case of ciguatoxin CTX3C-ABC and its specific antibody 1C49

scientific article

Design and De Novo Synthesis of 6-Aza-artemisinins

scientific article published on 23 July 2018

Divergent and expeditious access to fused skeletons inspired by indole alkaloids and transtaganolides.

scientific article

Diversification of echinomycin molecular structure by way of chemoenzymatic synthesis and heterologous expression of the engineered echinomycin biosynthetic pathway

scientific article

Enantioselective synthesis of the fully functionalized ABC ring of zoanthenol

scientific article published on 01 September 2008

Enzymatic epoxide-opening cascades catalyzed by a pair of epoxide hydrolases in the ionophore polyether biosynthesis

scientific article published on 04 March 2011

Enzymatic macrolactonization in the presence of DNA leading to triostin A analogs

scientific article published in August 2008

Epoxide hydrolase Lsd19 for polyether formation in the biosynthesis of lasalocid A: direct experimental evidence on polyene-polyepoxide hypothesis in polyether biosynthesis

scientific article published on 19 August 2008

Generation of Anti-trypanosomal Agents through Concise Synthesis and Structural Diversification of Sesquiterpene Analogues ⬇️

scientific article published on March 17, 2011

Heterologous expression of highly reducing polyketide synthase involved in betaenone biosynthesis

scientific article published on 01 February 2015

Hg(OTf)(2)-catalyzed direct vinylation of tryptamines and versatile applications for tandem reactions

scientific article published on 23 April 2012

Identification and stereochemical assignment of the beta-hydroxytryptophan intermediate in the echinomycin biosynthetic pathway

scientific article published on 01 October 2006

Impact of the E540V Amino Acid Substitution in GyrB of Mycobacterium tuberculosis on Quinolone Resistance ⬇️

scientific article published on June 6, 2011

Intriguing substrate tolerance of epoxide hydrolase Lsd19 involved in biosynthesis of the ionophore antibiotic lasalocid A.

scientific article published in May 2010

Involvement of common intermediate 3-hydroxy-L-kynurenine in chromophore biosynthesis of quinomycin family antibiotics.

scientific article published on 24 November 2010

Nickel-catalyzed dimerization of pyrrolidinoindoline scaffolds: systematic access to chimonanthines, folicanthines and (+)-WIN 64821

scientific article published on 01 January 2014

Parallel and four-step synthesis of natural-product-inspired scaffolds through modular assembly and divergent cyclization

scientific article

Phage-display selection of antibodies to the left end of CTX3C using synthetic fragments.

scientific article

Pictet-Spenglerase involved in tetrahydroisoquinoline antibiotic biosynthesis.

scientific article published on 10 March 2012

Rationally engineered total biosynthesis of a synthetic analogue of a natural quinomycin depsipeptide in Escherichia coli

scientific article

Reconstruction of the saframycin core scaffold defines dual Pictet-Spengler mechanisms.

scientific article

Relative and absolute configuration of antitumor agent SW-163D.

scientific article published on 7 December 2007

Sequential [6+2], [2+2], and [3+2] annulations for rapid assembly of multiple fragments

scientific article published on 01 March 2013

Sequential enzymatic epoxidation involved in polyether lasalocid biosynthesis

scientific article published on 20 April 2012

Skeletal and stereochemical diversification of tricyclic frameworks inspired by Ca(2+)-ATPase inhibitors, artemisinin and transtaganolide D

scientific article published on 01 February 2009

Skeletal diversity via a folding pathway: synthesis of indole alkaloid-like skeletons

scientific article published on 01 January 2005

Solanapyrone synthase, a possible Diels-Alderase and iterative type I polyketide synthase encoded in a biosynthetic gene cluster from Alternaria solani

scientific article

Stereodivergent Synthesis of Bispyrrolidinoindoline Alkaloidal Scaffolds and Generation of a Lead Candidate with Stereospecific Antiproliferative Activity

scientific article published on 28 March 2019

Synthesis of multiply substituted 1,6-dihydropyridines through Cu(I)-catalyzed 6-endo cyclization

scientific article published on 01 June 2015

Synthesis of the fully functionalized ABCDE ring moiety of ciguatoxin

scientific article published on 01 March 2004

Synthesis-based approach toward direct sandwich immunoassay for ciguatoxin CTX3C.

scientific article

The Pictet-Spengler mechanism involved in the biosynthesis of tetrahydroisoquinoline antitumor antibiotics: a novel function for a nonribosomal peptide synthetase.

scientific article published in January 2012

Total biosynthesis of antitumor nonribosomal peptides in Escherichia coli.

scientific article

Total synthesis of alkaloids using both chemical and biochemical methods

scientific article published on 06 March 2020

Total synthesis of ciguatoxin CTX3C.

scientific article

Zn(OTf)2-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds

scientific article published on 01 May 2019

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