List of works - Tomohiro Kabuta

4-Hydroxynonenal induces persistent insolubilization of TDP-43 and alters its intracellular localization.

scientific article published on 18 May 2015

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development

scientific article

Abnormal instability, excess density, and aberrant morphology of dendritic spines in prenatally testosterone-exposed mice

scientific article

Age-dependent sensitivity to glucocorticoids in the developing mouse basolateral nucleus of the amygdala

scientific article published on 19 April 2014

An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding

scientific article published on 13 March 2015

Association of ubiquitin carboxy-terminal hydrolase-L1 in cerebrospinal fluid with clinical severity in a cohort of patients with Guillain-Barré syndrome

scientific article

Cytosolic domain of SIDT2 carries an arginine-rich motif that binds to RNA/DNA and is important for the direct transport of nucleic acids into lysosomes

scientific article published on 16 January 2020

Deficiency of ubiquitin carboxy-terminal hydrolase-L1 (UCH-L1) leads to vulnerability to lipid peroxidation

scientific article published on 4 May 2010

Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome

scientific article published in Journal of Biological Chemistry

Differential subcellular localization of insulin receptor substrates depends on C-terminal regions and importin beta

scientific article published in October 2008

Direct uptake and degradation of DNA by lysosomes

scientific article published on 21 May 2013

Discovery of a novel type of autophagy targeting RNA

scientific article published on 4 January 2013

Disturbance in Maternal Environment Leads to Abnormal Synaptic Instability during Neuronal Circuitry Development

scientific article published on 06 February 2017

Does proteasome [corrected] inhibition decrease or accelerate toxin-induced dopaminergic neurodegeneration?

scientific article

Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.

scientific article

GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation

scientific journal article

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Identification of a novel chemical potentiator and inhibitors of UCH-L1 by in silico drug screening

scientific article published on 6 February 2010

Insulin receptor substrate-3 functions as transcriptional activator in the nucleus

scientific journal article

Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity

scientific article published on 11 March 2010

Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies

scientific article

Lysosomal degradation of intracellular nucleic acids-multiple autophagic pathways

scientific article published on 30 December 2016

Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes

scientific article

Lysosomal storage and advanced senescence in the brain of LAMP-2-deficient Danon disease

scientific article published on 23 December 2012

Lysosomal-associated membrane protein 2 isoforms are differentially affected in early Parkinson's disease

scientific article published on 16 January 2015

Maternal high-fat diet leads to persistent synaptic instability in mouse offspring via oxidative stress during lactation

scientific article published on 9 March 2016

Parkinson's disease-associated mutations in α-synuclein and UCH-L1 inhibit the unconventional secretion of UCH-L1.

scientific article published on 12 June 2011

Pathology-associated change in levels and localization of SIDT2 in postmortem brains of Parkinson's disease and dementia with Lewy bodies patients

scientific article published in 2022

Property of lysosomal storage disease associated with midbrain pathology in the central nervous system of Lamp-2-deficient mice

scientific article

Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse

scientific article published on 25 December 2008

RNautophagy/DNautophagy possesses selectivity for RNA/DNA substrates

scientific article published in June 2015

Reduction in memory in passive avoidance learning, exploratory behaviour and synaptic plasticity in mice with a spontaneous deletion in the ubiquitin C-terminal hydrolase L1 gene

scientific article published in February 2008

Reduction of abnormal behavioral response to brief restraint by information from other mice in dystrophin-deficient mdx mice

scientific article published on 16 June 2010

Roles of Multiple Types of Autophagy in Neurodegenerative Diseases

SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells

scientific article published on 9 March 2017

TDP-43 associates with stalled ribosomes and contributes to cell survival during cellular stress

scientific article published on March 2013

TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase

article published in 2010

The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation

scientific article published on 11 March 2013

Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity

scientific article published on 29 March 2013

Ubiquitin C-terminal hydrolase-L3-knockout mice are resistant to diet-induced obesity and show increased activation of AMP-activated protein kinase in skeletal muscle

scientific article published on 11 August 2009

Virtual screening identification of novel chemical inhibitors for aberrant interactions between pathogenic mutant SOD1 and tubulin

scientific article published on 01 March 2019

List of works by Tomohiro Kabuta

4-Hydroxynonenal induces persistent insolubilization of TDP-43 and alters its intracellular localization.

A novel 4EHP-GIGYF2 translational repressor complex is essential for mammalian development

Abnormal instability, excess density, and aberrant morphology of dendritic spines in prenatally testosterone-exposed mice

Age-dependent sensitivity to glucocorticoids in the developing mouse basolateral nucleus of the amygdala

An RNautophagy/DNautophagy receptor, LAMP2C, possesses an arginine-rich motif that mediates RNA/DNA-binding

Association of ubiquitin carboxy-terminal hydrolase-L1 in cerebrospinal fluid with clinical severity in a cohort of patients with Guillain-Barré syndrome

Cytosolic domain of SIDT2 carries an arginine-rich motif that binds to RNA/DNA and is important for the direct transport of nucleic acids into lysosomes

Deficiency of ubiquitin carboxy-terminal hydrolase-L1 (UCH-L1) leads to vulnerability to lipid peroxidation

Degradation of Amyotrophic Lateral Sclerosis-linked Mutant Cu,Zn-Superoxide Dismutase Proteins by Macroautophagy and the Proteasome

Differential subcellular localization of insulin receptor substrates depends on C-terminal regions and importin beta

Direct uptake and degradation of DNA by lysosomes

Discovery of a novel type of autophagy targeting RNA

Disturbance in Maternal Environment Leads to Abnormal Synaptic Instability during Neuronal Circuitry Development

Does proteasome [corrected] inhibition decrease or accelerate toxin-induced dopaminergic neurodegeneration?

Dopaminergic neuronal loss in transgenic mice expressing the Parkinson's disease-associated UCH-L1 I93M mutant.

GIGYF2 is present in endosomal compartments in the mammalian brains and enhances IGF-1-induced ERK1/2 activation

Guidelines for the use and interpretation of assays for monitoring autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Identification of a novel chemical potentiator and inhibitors of UCH-L1 by in silico drug screening

Insulin receptor substrate-3 functions as transcriptional activator in the nucleus

Insulin receptor substrate-3, interacting with Bcl-3, enhances p50 NF-kappaB activity

Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies

Lysosomal degradation of intracellular nucleic acids-multiple autophagic pathways

Lysosomal membrane protein SIDT2 mediates the direct uptake of DNA by lysosomes

Lysosomal storage and advanced senescence in the brain of LAMP-2-deficient Danon disease

Lysosomal-associated membrane protein 2 isoforms are differentially affected in early Parkinson's disease

Maternal high-fat diet leads to persistent synaptic instability in mouse offspring via oxidative stress during lactation

Parkinson's disease-associated mutations in α-synuclein and UCH-L1 inhibit the unconventional secretion of UCH-L1.

Pathology-associated change in levels and localization of SIDT2 in postmortem brains of Parkinson's disease and dementia with Lewy bodies patients

Property of lysosomal storage disease associated with midbrain pathology in the central nervous system of Lamp-2-deficient mice

Proteomic and histochemical analysis of proteins involved in the dying-back-type of axonal degeneration in the gracile axonal dystrophy (gad) mouse

RNautophagy/DNautophagy possesses selectivity for RNA/DNA substrates

Reduction in memory in passive avoidance learning, exploratory behaviour and synaptic plasticity in mice with a spontaneous deletion in the ubiquitin C-terminal hydrolase L1 gene

Reduction of abnormal behavioral response to brief restraint by information from other mice in dystrophin-deficient mdx mice

Roles of Multiple Types of Autophagy in Neurodegenerative Diseases

SIDT2 mediates gymnosis, the uptake of naked single-stranded oligonucleotides into living cells

TDP-43 associates with stalled ribosomes and contributes to cell survival during cellular stress

TDP-43 physically interacts with amyotrophic lateral sclerosis-linked mutant CuZn superoxide dismutase

The AP-1 complex regulates intracellular localization of insulin receptor substrate 1, which is required for insulin-like growth factor I-dependent cell proliferation

Ubiquitin C-terminal hydrolase L1 (UCH-L1) acts as a novel potentiator of cyclin-dependent kinases to enhance cell proliferation independently of its hydrolase activity

Ubiquitin C-terminal hydrolase-L3-knockout mice are resistant to diet-induced obesity and show increased activation of AMP-activated protein kinase in skeletal muscle

Virtual screening identification of novel chemical inhibitors for aberrant interactions between pathogenic mutant SOD1 and tubulin