List of works by Jennifer Southgate

A Rare Urachal Cyst in a Case of Ketamine-induced Cystitis Provides Mechanistic Insights

scientific article published on 29 December 2015

A biomimetic tissue from cultured normal human urothelial cells: analysis of physiological function

scientific article published on 22 March 2005

A novel bidirectional positive-feedback loop between Wnt-β-catenin and EGFR-ERK plays a role in context-specific modulation of epithelial tissue regeneration.

scientific article published on 9 May 2014

A novel epigenetic phenotype associated with the most aggressive pathway of bladder tumor progression

scientific article

A novel mechanism of CD40-induced apoptosis of carcinoma cells involving TRAF3 and JNK/AP-1 activation.

scientific article published on 20 January 2006

A protein of squamous keratinising epithelium from odontogenic keratocyst fluid

scientific article published in January 1986

A redox state-dictated signalling pathway deciphers the malignant cell specificity of CD40-mediated apoptosis

scientific article published on 21 November 2016

A surgical model of composite cystoplasty with cultured urothelial cells: a controlled study of gross outcome and urothelial phenotype.

scientific article published in March 2004

Activation of peroxisome proliferator-activated receptor-gamma reverses squamous metaplasia and induces transitional differentiation in normal human urothelial cells

scientific article published on May 2004

Agent-based computational modeling of wounded epithelial cell monolayers.

scientific article

An integrated agent-mathematical model of the effect of intercellular signalling via the epidermal growth factor receptor on cell proliferation.

scientific article published on 9 May 2006

Analysis of apoptosis in the preimplantation bovine embryo using TUNEL.

scientific article published in September 1999

Anti-social cells: predicting the influence of E-cadherin loss on the growth of epithelial cell populations.

scientific article published on 21 October 2009

Antibodies to normal human colon membranes: preparation, characterization and tissue distribution

scientific article published in June 1985

Aquaporin expression contributes to human transurothelial permeability in vitro and is modulated by NaCl.

scientific article

Assessing UK specialists’ knowledge of the diagnostic criteria for painful bladder syndrome/interstitial cystitis

scientific article published on 21 December 2007

Augmentation of the insufficient tissue bed for surgical repair of hypospadias using acellular matrix grafts: A proof of concept study

scientific article published on 01 January 2021

Autocrine regulation of human urothelial cell proliferation and migration during regenerative responses in vitro

scientific article published in May 2005

Bilateral congenital pseudarthrosis of the olecranon presenting in an adult

scientific article published on 09 April 2010

Bio-engineering urothelial cells for bladder tissue transplant

scientific article published on 01 August 2008

Biomimetic urothelial tissue models for the in vitro evaluation of barrier physiology and bladder drug efficacy

scientific article published on 17 April 2014

Bladder organoids: a step towards personalised cancer therapy?

scientific article published on 01 July 2019

Bladder reconstruction--from cells to materials

scientific article

Calcium signalling in wound-responsive normal human urothelial cell monolayers.

scientific article published on 15 April 2008

Cell-type-specific modelling of intracellular calcium signalling: a urothelial cell model

scientific article published on 17 July 2013

Cellular integration and vascularisation promoted by a resorbable, particulate-leached, cross-linked poly(ε-caprolactone) scaffold

scientific article published on 22 February 2011

Changes in surface structure and concanavalin A-binding capacity of urothelium in the mouse bladder after whole-body neutron irradiation

scientific article published in January 1985

Characterisation of electrospun polystyrene scaffolds for three-dimensional in vitro biological studies

scientific article published on 10 February 2006

Characterization and classification of adherent cells in monolayer culture using automated tracking and evolutionary algorithms

scientific article published on 3 June 2016

Culture of ascitic ovarian cancer cells as a clinically-relevant ex vivo model for the assessment of biological therapies.

scientific article published in January 1998

Current status of tissue engineering in urology

scientific article

Cyclin E is recruited to the nuclear matrix during differentiation, but is not recruited in cancer cells.

scientific article published on 24 November 2010

Cytokeratin 20 as an objective marker of urothelial dysplasia.

scientific article published in December 1996

Cytokeratin 20 expression by non-invasive transitional cell carcinomas: potential for distinguishing recurrent from non-recurrent disease.

scientific article published in August 1995

Deregulation of Rab and Rab effector genes in bladder cancer.

scientific article

Detection of melanoma cells in peripheral blood by means of reverse transcriptase and polymerase chain reaction

scientific article published on November 1991

Development and characterisation of a full-thickness acellular porcine bladder matrix for tissue engineering

scientific article published on 7 November 2006

Differential Display

scientific article published on 01 January 2001

Differential expression of Oct4 variants and pseudogenes in normal urothelium and urothelial cancer

scientific article published on 8 August 2013

Differential regulation of growth-promoting signalling pathways by E-cadherin

scientific article

Differential susceptibility to TRAIL of normal versus malignant human urothelial cells.

scientific article published on 13 January 2006

Differential transcription factor expression by human epithelial cells of buccal and urothelial derivation

scientific article published on 26 May 2018

Differentiation potential of urothelium from patients with benign bladder dysfunction

scientific article

Differentiation-associated reprogramming of the transforming growth factor β receptor pathway establishes the circuitry for epithelial autocrine/paracrine repair

scientific article

Differentiation-associated urothelial cytochrome P450 oxidoreductase predicates the xenobiotic-metabolizing activity of "luminal" muscle-invasive bladder cancers.

scientific article

EGFR as a potential therapeutic target for a subset of muscle-invasive bladder cancers presenting a basal-like phenotype

scientific article

Effect of long-chain fatty acids on human urothelial cells in organ culture

article

Effects of PPAR agonists on proliferation and differentiation in human urothelium

scientific article published on 20 June 2008

Effects of insulin-like growth factors I and II on tumour-necrosis-factor-a-induced apoptosis in early murine embryos

scientific article published on 01 January 2002

Effects of loss of p53 and p16 function on life span and survival of human urothelial cells

scientific article published on 01 September 2005

Experimental models of human bladder carcinogenesis.

scientific article

Expression and cytokine regulation of immune recognition elements by normal human biliary epithelial and established liver cell lines in vitro.

scientific article published on October 1998

Expression and localisation of aquaporin water channels in human urothelium in situ and in vitro

scientific article

Expression of CD44 on bile ducts in primary sclerosing cholangitis and primary biliary cirrhosis.

scientific article published on October 1999

Expression of activation and costimulatory elements by human intestinal intraepithelial lymphocytes.

scientific article published in July 1999

Expression of an antigen associated with basal bodies of human ciliated epithelial cells.

scientific article published on January 1999

Expression of cytokeratin 20 in urinary cytology of patients with bladder carcinoma

scientific article published on 01 September 1998

Expression of cytokeratin 20 redefines urothelial papillomas of the bladder.

scientific article published in March 1999

FOXA1 and IRF-1 intermediary transcriptional regulators of PPARgamma-induced urothelial cytodifferentiation

scientific article

From pathway to population--a multiscale model of juxtacrine EGFR-MAPK signalling.

scientific article

Functional expression of purinergic P2 receptors and transient receptor potential channels by the human urothelium

scientific article published on 29 May 2013

Generation of a functional, differentiated porcine urothelial tissue in vitro

scientific article

Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

scientific article published on 6 November 2017

Growth factor production during multistage transformation of epithelium in vitro. I. Partial purification and characterisation of the factor(s) from a fully transformed epithelial cell line.

scientific article

Hallux rigidus: the long-term results of dorsal wedge osteotomy and arthrodesis in adults.

scientific article published on March 1997

Heterarchy of transcription factors driving basal and luminal cell phenotypes in human urothelium

scientific article

Human Fallopian tubal epithelial cells in vitro: establishment of polarity and potential role of intracellular calcium and extracellular ATP in fluid secretion.

scientific article

Human hepatocellular carcinoma: cross-reactive and idiotypic antigens associated with malignant transformation of epithelial cells

scientific article published in May 1987

Human uroplakin lb gene structure and promoter analysis

scientific article

Hypoxic changes to the urothelium as a bystander of end-stage bladder disease

scientific article published on 05 February 2019

Identification of ELF3 as an early transcriptional regulator of human urothelium

scientific article published on 25 December 2013

Identification of genes involved in human urothelial cell-matrix interactions: implications for the progression pathways of malignant urothelium.

scientific article

Identification of genes up-regulated in urothelial tumors: the 67-kd laminin receptor and tumor-associated trypsin inhibitor

scientific article

Immortalisation of normal human urothelial cells compromises differentiation capacity.

scientific article published on 21 February 2011

Immunophenotype of transitional metaplasia of the uterine cervix.

scientific article published in April 1999

Implications of TERT promoter mutations and telomerase activity in urothelial carcinogenesis.

scientific article published on 29 March 2018

In vitro assessment of decellularized porcine dermis as a matrix for urinary tract reconstruction

scientific article

Independent component analysis uncovers the landscape of the bladder tumor transcriptome and reveals insights into luminal and basal subtypes

scientific article published on 13 November 2014

Induction of APOBEC3-mediated genomic damage in urothelium implicates BK polyomavirus (BKPyV) as a hit-and-run driver for bladder cancer

scientific article published on 22 February 2022

Induction of a differentiated ciliated cell phenotype in primary cultures of Fallopian tube epithelium.

scientific article published in November 1998

Influence of the physical properties of two-dimensional polyester substrates on the growth of normal human urothelial and urinary smooth muscle cells in vitro

scientific article published on 3 February 2007

Inhibition of T cell activation by normal human biliary epithelial cells

scientific article published on 01 December 1999

Inter-individual variation in urothelial DNA repair gene expression in vitro.

scientific article published on August 2002

Is tissue engineering and biomaterials the future for lower urinary tract dysfunction (LUTD)/pelvic organ prolapse (POP)?

scientific article published on June 2011

Ketamine-Induced Apoptosis in Normal Human Urothelial Cells: A Direct, N-Methyl-d-Aspartate Receptor-Independent Pathway Characterized by Mitochondrial Stress.

scientific article published on 16 March 2016

Loss of Janus Associated Kinase 1 Alters Urothelial Cell Function and Facilitates the Development of Bladder Cancer

scientific article published on 10 September 2019

Loss of cyclin-dependent kinase inhibitor genes and chromosome 9 karyotypic abnormalities in human bladder cancer cell lines ⬇️

scientific article published on November 1, 1995

L’Epidermal Growth Factor Receptor (EGFR) est une cible thérapeutique pour un sous-groupe de tumeurs de vessie agressives de phénotype de type basal

scientific article published on 30 October 2014

Micro-heterogenous expression of peanut agglutinin-binding sites in the extracellular matrix of cultured cells

scientific article published on 01 January 1985

Modelling cell signalling and differentiation in the urothelium

scientific article published in March 2005

Modified lateral radiograph for assessment of the radiocarpal joint following palmar plating of the distal radius

scientific article published on 01 April 2009

Monoclonal antibodies to human urothelial cell lines and hybrids: production and characterization.

scientific article

Multistage carcinogenesis induced by ras and myc oncogenes in a reconstituted organ.

scientific article published in March 1989

Mutation analyses of Uroplakin II in children with renal tract malformations

scientific article

N;-3 and n;-6 polyunsaturated fatty acids induce cytostasis in human urothelial cells independent of p53 gene function

scientific article published in September 2000

Nerve hyperplasia: a unique feature of ketamine cystitis

scientific article published on 8 October 2013

Normal human liver organ culture

article

Normal human urothelial cells in vitro: proliferation and induction of stratification.

scientific article

Novel urothelium specific gene expression identified by differential display reverse transcriptase-polymerase chain reaction

scientific article published in January 2006

Oestrogen receptor status of mast cells in interstitial cystitis

scientific article published on 01 March 1996

Organotypic and 3D reconstructed cultures of the human bladder and urinary tract

scientific article published on January 2011

PPAR alpha and PPAR gamma coactivation rapidly induces Egr-1 in the nuclei of the dorsal and ventral urinary bladder and kidney pelvis urothelium of rats

scientific article published in December 2009

PPARgamma-regulated tight junction development during human urothelial cytodifferentiation

scientific article

Patterns of splice variant CD44 expression by normal human urothelium in situ and in vitro and by bladder-carcinoma cell lines

scientific article published on August 1995

Permeability of differentiated human urothelium in vitro

scientific article published on January 2011

Plasticity of in vitro-generated urothelial cells for functional tissue formation

scientific article published on 7 February 2014

Publisher Correction: Genome-wide linkage and association study implicates the 10q26 region as a major genetic contributor to primary nonsyndromic vesicoureteric reflux

scientific article

RE

Rat Urinary Bladder Carcinogenesis by Dual-Acting PPARalpha + gamma Agonists

scientific article published on January 2008

Re: Cytokeratin 20: a new marker for early detection of bladder cell carcinoma

scientific article published on 01 August 1999

Reconstitution of Human Urothelium From Monolayer Cultures

article

Recreational ketamine: from pleasure to pain

scientific article published on 14 February 2011

Regenerative medicine in urology

scientific article

Regenerative medicine in urology.

scientific article

Regional biomechanical and histological characterisation of the passive porcine urinary bladder: Implications for augmentation and tissue engineering strategies

scientific article

Regional copy number-independent deregulation of transcription in cancer

scientific article published on 12 November 2006

Regulation of apoptosis in the bovine blastocyst by insulin and the insulin-like growth factor (IGF) superfamily.

scientific article

Relationship between E-cadherin and fibroblast growth factor receptor 2b expression in bladder carcinomas

scientific article published on 01 October 1999

Reprogramming stromal cells from the urinary tract and prostate: a trip to pluripotency and back?

scientific article

Reverse transcriptase-polymerase chain reaction for expression of tyrosinase to identify malignant melanoma cells in peripheral blood.

scientific article published in March 1996

Review: tissue engineering of the urinary bladder: considering structure-function relationships and the role of mechanotransduction

scientific article

Revised Classification of Urothelial Neoplasms

scientific article published on 01 January 2000

Role of PPARgamma and EGFR signalling in the urothelial terminal differentiation programme

scientific article published on 30 March 2004

Role of p53 in the responses of human urothelial cells to genotoxic damage.

scientific article published in July 2001

Sensitivity of normal, paramalignant, and malignant human urothelial cells to inhibitors of the epidermal growth factor receptor signaling pathway

scientific article published on January 2008

Seromuscular grafts for bladder reconstruction: extra-luminal demucosalisation of the bowel

scientific article published on November 2012

Sources of variability in cytosolic calcium transients triggered by stimulation of homogeneous uro-epithelial cell monolayers

scientific article

Specificity of the Metallothionein-1 Response by Cadmium-Exposed Normal Human Urothelial Cells ⬇️

journal article from 'International Journal of Molecular Sciences' published in 2019

Stromal and vascular invasion in an human in vitro bladder cancer model.

scientific article published in June 1997

Structurally diverse peroxisome proliferator-activated receptor agonists induce apoptosis in human uro-epithelial cells by a receptor-independent mechanism involving store-operated calcium channels.

scientific article published on 10 July 2009

Study of the cell biology and biochemistry of cherubism

scientific article

Subcutaneous administration of recombinant glycosylated interleukin 6 in patients with cancer: pharmacokinetics, pharmacodynamics and immunomodulatory effects.

scientific article published in April 2000

Surface Shave: Revealing the Apical-Restricted Uroglycome

scientific article published in 2022

Synthesis of jaspaquinol and effect on viability of normal and malignant bladder epithelial cell lines

scientific article published on June 2004

T cell and mononuclear phagocyte populations of the human small and large intestine.

scientific article published in January 1987

Targeting Deficiencies in the TLR5 Mediated Vaginal Response to Treat Female Recurrent Urinary Tract Infection

scientific article published on 8 September 2017

The acute medicine - speciality interface: experience in a large teaching hospital

scientific article published on 01 January 2011

The effect of low-intensity pulsed ultrasound on repair of epithelial cell monolayers in vitro.

scientific article

The effects of dietary fatty acids on the proliferation of normal human urothelial cells in vitro.

scientific article

The effects of malignant transformation on susceptibility of human urothelial cells to CD40-mediated apoptosis.

scientific article published in September 2002

The epitheliome: agent-based modelling of the social behaviour of cells.

scientific article published in August 2004

The human tissue-biomaterial interface: a role for PPARγ-dependent glucocorticoid receptor activation in regulating the CD163+ M2 macrophage phenotype

scientific article

The human urothelial tight junction: claudin 3 and the ZO-1α(+) switch

scientific article

The modulatory effect of cell–cell contact on the tumourigenic potential of pre-malignant epithelial cells: a computational exploration

scientific article published on 24 October 2012

The relationship between the mechanical properties and cell behaviour on PLGA and PCL scaffolds for bladder tissue engineering

scientific article

The role of matrix metalloproteinases in an in vitro model of bladder tumor invasion.

scientific article published in January 1999

The virtual cell--a candidate co-ordinator for 'middle-out' modelling of biological systems

scientific article published on 17 March 2009

Tissue engineering and stem cell research in urology.

scientific article

Tissue engineering potential of urothelial cells from diseased bladders.

scientific article published on 23 September 2011

Toll-like receptor responses of normal human urothelial cells to bacterial flagellin and lipopolysaccharide

scientific article published on 23 July 2011

Towards control of smooth muscle cell differentiation in synthetic 3D scaffolds

scientific article published on 15 May 2008

Towards defining roles and relationships for tenascin-C and TGFbeta-1 in the normal and neoplastic urinary bladder.

scientific article

Trans-species comparison of PPAR and RXR expression by rat and human urothelial tissues.

scientific article published on 25 April 2008

Transcriptional control of the human urothelial-specific gene, uroplakin Ia.

scientific article

Transforming growth factor-beta promotes 'death by neglect' in post-activated human T cells

scientific article published on March 2001

Transplantation of autologous differentiated urothelium in an experimental model of composite cystoplasty

scientific article

Uroplakin gene expression by normal and neoplastic human urothelium

scientific article

Uroplakin gene expression in normal human tissues and locally advanced bladder cancer

scientific article

Urothelial cell transplantation using biodegradable synthetic scaffolds

scientific article published in October 2001

Urothelial differentiation in chronically urine-deprived bladders of patients with end-stage renal disease

scientific article published in September 2005

Urothelial differentiation in vesicoureteric reflux and other urological disorders of childhood: a comparative study.

scientific article published on 2 November 2005

Urothelial tissue culture for bladder reconstruction: an experimental study.

scientific article published in August 1993

Urothelial tissue regulation. Unraveling the role of the stroma

scientific article

Use of donor bladder tissues for in vitro research

scientific article published in January 2014

Use of primary cultures of rabbit oviduct epithelial cells to study the ionic basis of tubal fluid formation.

scientific article

Which proliferation markers for routine immunohistology?

scientific article published on March 1996

p68 RNA helicase: identification of a nucleolar form and cloning of related genes containing a conserved intron in yeasts

scientific article

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