List of works - Rüdiger Ettrich

1.2 Å resolution crystal structure of Escherichia coli WrbA holoprotein

scientific article

4-Deoxy-substrates for beta-N-acetylhexosaminidases: how to make use of their loose specificity.

scientific article published on 14 April 2010

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription

scientific article published on 22 December 2015

A computational study of the oligosaccharide binding sites in the lectin-like domain of Tumor Necrosis Factor and the TNF-derived TIP peptide

scientific article

A refined atomic scale model of the Saccharomyces cerevisiae K+-translocation protein Trk1p combined with experimental evidence confirms the role of selectivity filter glycines and other key residues

scientific article published on 14 February 2015

A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I

scientific article published on 26 June 2018

ATP-binding is stabilized by a stacking interaction within the binding site of Na+/K+ -ATPase

scientific article

Backbone assignment and secondary structure of the PsbQ protein from photosystem II

2011 scientific article

Binding-competent states for L-arginine in E. coli arginine repressor apoprotein.

scientific article

Biphasic Kinetic Behavior of E. coli WrbA, an FMN-Dependent NAD(P)H:Quinone Oxidoreductase ⬇️

scientific article published on August 29, 2012

Charybdotoxin and margatoxin acting on the human voltage-gated potassium channel hKv1.3 and its H399N mutant: an experimental and computational comparison

scientific article published on 19 April 2012

Charybdotoxin unbinding from the mKv1.3 potassium channel: a combined computational and experimental study

scientific article published on 13 September 2011

Cholesterol modulates Orai1 channel function

scientific article published on 26 January 2016

Communication between N-terminus and Loop2 tunes Orai activation.

scientific article published on 13 December 2017

Computational study of β-N-acetylhexosaminidase from Talaromyces flavus, a glycosidase with high substrate flexibility

scientific article

Conserved Dynamic Mechanism of Allosteric Response to L-arg in Divergent Bacterial Arginine Repressors

scientific article published on 10 May 2020

Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1).

scientific article

Crystal structure of a novel domain of the motor subunit of the Type I restriction enzyme EcoR124 involved in complex assembly and DNA binding

scientific article published on 27 July 2018

Crystallization and preliminary crystallographic characterization of the extrinsic PsbP protein of photosystem II from Spinacia oleracea.

scientific article published on 7 January 2009

Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.

scientific article published in June 2003

Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel

scientific article

Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β-N-acetylhexosaminidase.

scientific article

Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.

scientific article published on 5 May 2009

Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents

scientific article

Expression, characterization and homology modeling of a novel eukaryotic GH84 β-N-acetylglucosaminidase from Penicillium chrysogenum

scientific article published on 14 January 2014

Functional coupling of duplex translocation to DNA cleavage in a type I restriction enzyme

scientific article published on 3 June 2015

Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

scientific article

In silico characterization of the motor subunit of the e.coli. restriction-modification system EcoR1241

Influence of ligand binding on structure and thermostability of human α1-acid glycoprotein.

scientific article published on 24 September 2015

Inhibition of GlcNAc-processing glycosidases by C-6-azido-NAG-thiazoline and its derivatives

scientific article published on 20 March 2014

Inhibition of human serine racemase, an emerging target for medicinal chemistry.

scientific article published on June 2011

Interaction of organic solvents with protein structures at protein-solvent interface

scientific article published on 4 July 2012

Interdomain communication in the endonuclease/motor subunit of type I restriction-modification enzyme EcoR124I

scientific article published on 28 June 2014

Localization of catalytic active sites in the large cytoplasmic domain of Na+/K+-ATPase

scientific article published in April 2003

Mechanistic insights into the Orai channel by molecular dynamics simulations

scientific article published on 15 January 2019

Molecular dynamics comparison of E. coli WrbA apoprotein and holoprotein.

scientific article

Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.

scientific article

Phe(475) and Glu(446) but not Ser(445) participate in ATP-binding to the alpha-subunit of Na(+)/K(+)-ATPase

scientific article published in September 2002

Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA

scientific article

Raman Spectroscopy Adds Complementary Detail to the High-Resolution X-Ray Crystal Structure of Photosynthetic PsbP from Spinacia oleracea

scientific article

Regulation of the transient receptor potential channel TRPA1 by its N-terminal ankyrin repeat domain

scientific article published on 3 July 2012

Resonance assignment of PsbP: an extrinsic protein from photosystem II of Spinacia oleracea

scientific article

Retraction: Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

Secondary and tertiary structure of nucleotide-binding domain of alphasubunit of Na+/K+-ATPase

scientific article

Sequential activation of STIM1 links Ca2+ with luminal domain unfolding

scientific article published on 19 November 2019

Solution NMR and molecular dynamics reveal a persistent alpha helix within the dynamic region of PsbQ from photosystem II of higher plants

scientific article published on 02 July 2015

Structural analysis of natural killer cell receptor protein 1 (NKR-P1) extracellular domains suggests a conserved long loop region involved in ligand specificity

scientific article published on 14 September 2010

Structural model of lymphocyte receptor NKR-P1C revealed by mass spectrometry and molecular modeling

article

Structural organization of WrbA in apo- and holoprotein crystals

scientific article

Structure and dynamics of the N-terminal loop of PsbQ from photosystem II of Spinacia oleracea

scientific article published on 27 April 2006

Structure of human alpha1-acid glycoprotein and its high-affinity binding site

scientific article published in January 2003

Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.

scientific article

Structure of the motor subunit of type I restriction-modification complex EcoR124I

scientific article published in January 2009

Study of chaperone-like activity of human haptoglobin: conformational changes under heat shock conditions and localization of interaction sites

scientific article

Symmetric allosteric mechanism of hexameric Escherichia coli arginine repressor exploits competition between L-arginine ligands and resident arginine residues.

scientific article

Synergy of Molecular Dynamics and Isothermal Titration Calorimetry in Studies of Allostery

article

The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1.

scientific article published on January 2011

The helical domain of the EcoR124I motor subunit participates in ATPase activity and dsDNA translocation.

scientific article

The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.

scientific article

The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site.

scientific article published in October 2004

The α-galactosidase type A gene aglA from Aspergillus niger encodes a fully functional α-N-acetylgalactosaminidase.

scientific article

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.

scientific article published on 28 November 2017

WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases.

scientific article published on October 2007

pHluorin-assisted expression, purification, crystallization and X-ray diffraction data analysis of the C-terminal domain of the HsdR subunit of the Escherichia coli type I restriction-modification system EcoR124I.

scientific article

List of works by Rüdiger Ettrich

1.2 Å resolution crystal structure of Escherichia coli WrbA holoprotein

4-Deoxy-substrates for beta-N-acetylhexosaminidases: how to make use of their loose specificity.

A calcium-accumulating region, CAR, in the channel Orai1 enhances Ca(2+) permeation and SOCE-induced gene transcription

A computational study of the oligosaccharide binding sites in the lectin-like domain of Tumor Necrosis Factor and the TNF-derived TIP peptide

A refined atomic scale model of the Saccharomyces cerevisiae K+-translocation protein Trk1p combined with experimental evidence confirms the role of selectivity filter glycines and other key residues

A residue of motif III positions the helicase domains of motor subunit HsdR in restriction-modification enzyme EcoR124I

ATP-binding is stabilized by a stacking interaction within the binding site of Na+/K+ -ATPase

Backbone assignment and secondary structure of the PsbQ protein from photosystem II

Binding-competent states for L-arginine in E. coli arginine repressor apoprotein.

Biphasic Kinetic Behavior of E. coli WrbA, an FMN-Dependent NAD(P)H:Quinone Oxidoreductase ⬇️

Charybdotoxin and margatoxin acting on the human voltage-gated potassium channel hKv1.3 and its H399N mutant: an experimental and computational comparison

Charybdotoxin unbinding from the mKv1.3 potassium channel: a combined computational and experimental study

Cholesterol modulates Orai1 channel function

Communication between N-terminus and Loop2 tunes Orai activation.

Computational study of β-N-acetylhexosaminidase from Talaromyces flavus, a glycosidase with high substrate flexibility

Conserved Dynamic Mechanism of Allosteric Response to L-arg in Divergent Bacterial Arginine Repressors

Contribution of the putative inner-pore region to the gating of the transient receptor potential vanilloid subtype 1 channel (TRPV1).

Crystal structure of a novel domain of the motor subunit of the Type I restriction enzyme EcoR124 involved in complex assembly and DNA binding

Crystallization and preliminary crystallographic characterization of the extrinsic PsbP protein of photosystem II from Spinacia oleracea.

Eight amino acids form the ATP recognition site of Na(+)/K(+)-ATPase.

Engineering enzyme stability and resistance to an organic cosolvent by modification of residues in the access tunnel

Enzymatic characterization and molecular modeling of an evolutionarily interesting fungal β-N-acetylhexosaminidase.

Essential role for the putative S6 inner pore region in the activation gating of the human TRPA1 channel.

Expansion of access tunnels and active-site cavities influence activity of haloalkane dehalogenases in organic cosolvents

Expression, characterization and homology modeling of a novel eukaryotic GH84 β-N-acetylglucosaminidase from Penicillium chrysogenum

Functional coupling of duplex translocation to DNA cleavage in a type I restriction enzyme

Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

In silico characterization of the motor subunit of the e.coli. restriction-modification system EcoR1241

Influence of ligand binding on structure and thermostability of human α1-acid glycoprotein.

Inhibition of GlcNAc-processing glycosidases by C-6-azido-NAG-thiazoline and its derivatives

Inhibition of human serine racemase, an emerging target for medicinal chemistry.

Interaction of organic solvents with protein structures at protein-solvent interface

Interdomain communication in the endonuclease/motor subunit of type I restriction-modification enzyme EcoR124I

Localization of catalytic active sites in the large cytoplasmic domain of Na+/K+-ATPase

Mechanistic insights into the Orai channel by molecular dynamics simulations

Molecular dynamics comparison of E. coli WrbA apoprotein and holoprotein.

Molecular modeling of human MT2 melatonin receptor: the role of Val204, Leu272 and Tyr298 in ligand binding.

Phe(475) and Glu(446) but not Ser(445) participate in ATP-binding to the alpha-subunit of Na(+)/K(+)-ATPase

Quantum Calculations Indicate Effective Electron Transfer between FMN and Benzoquinone in a New Crystal Structure of Escherichia coli WrbA

Raman Spectroscopy Adds Complementary Detail to the High-Resolution X-Ray Crystal Structure of Photosynthetic PsbP from Spinacia oleracea

Regulation of the transient receptor potential channel TRPA1 by its N-terminal ankyrin repeat domain

Resonance assignment of PsbP: an extrinsic protein from photosystem II of Spinacia oleracea

Retraction: Heterologous expression, purification and characterization of nitrilase from Aspergillus niger K10

Secondary and tertiary structure of nucleotide-binding domain of alphasubunit of Na+/K+-ATPase

Sequential activation of STIM1 links Ca2+ with luminal domain unfolding

Solution NMR and molecular dynamics reveal a persistent alpha helix within the dynamic region of PsbQ from photosystem II of higher plants

Structural analysis of natural killer cell receptor protein 1 (NKR-P1) extracellular domains suggests a conserved long loop region involved in ligand specificity

Structural model of lymphocyte receptor NKR-P1C revealed by mass spectrometry and molecular modeling

Structural organization of WrbA in apo- and holoprotein crystals

Structure and dynamics of the N-terminal loop of PsbQ from photosystem II of Spinacia oleracea

Structure of human alpha1-acid glycoprotein and its high-affinity binding site

Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.

Structure of the motor subunit of type I restriction-modification complex EcoR124I

Study of chaperone-like activity of human haptoglobin: conformational changes under heat shock conditions and localization of interaction sites

Symmetric allosteric mechanism of hexameric Escherichia coli arginine repressor exploits competition between L-arginine ligands and resident arginine residues.

Synergy of Molecular Dynamics and Isothermal Titration Calorimetry in Studies of Allostery

The C-terminal basic residues contribute to the chemical- and voltage-dependent activation of TRPA1.

The helical domain of the EcoR124I motor subunit participates in ATPase activity and dsDNA translocation.

The hydrogen bonds between Arg423 and Glu472 and other key residues, Asp443, Ser477, and Pro489, are responsible for the formation and a different positioning of TNP-ATP and ATP within the nucleotide-binding site of Na(+)/K(+)-ATPase.

The phosphatase activity of the isolated H4-H5 loop of Na+/K+ ATPase resides outside its ATP binding site.

The α-galactosidase type A gene aglA from Aspergillus niger encodes a fully functional α-N-acetylgalactosaminidase.

Transmembrane helix connectivity in Orai1 controls two gates for calcium-dependent transcription.

WrbA bridges bacterial flavodoxins and eukaryotic NAD(P)H:quinone oxidoreductases.

pHluorin-assisted expression, purification, crystallization and X-ray diffraction data analysis of the C-terminal domain of the HsdR subunit of the Escherichia coli type I restriction-modification system EcoR124I.