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List of works by Danny J Eckert

A Novel Model to Estimate Key OSA Endotypes from Standard Polysomnography and Clinical Data and Their Contribution to OSA Severity

scientific article published on 16 October 2020

A method for measuring and modeling the physiological traits causing obstructive sleep apnea ⬇️

scientific article published on March 24, 2011

A pragmatic, phase III, multisite, double-blind, placebo-controlled, parallel-arm, dose increment randomised trial of regular, low-dose extended-release morphine for chronic breathlessness: Breathlessness, Exertion And Morphine Sulfate (BEAMS) study

scientific article published on 17 July 2017

A secondary reflex suppression phase is present in genioglossus but not tensor palatini in response to negative upper airway pressure.

scientific article

A systematic review and meta-analysis of upper airway sensation in obstructive sleep apnea – Implications for pathogenesis, treatment and future research directions

scientific article published in April 2022

Acetazolamide improves loop gain but not the other physiological traits causing obstructive sleep apnoea.

scientific article published on 4 January 2012

Acute sustained hypoxia suppresses the cough reflex in healthy subjects

scientific article published in December 2005

Alcohol Alters Sensory Processing to Respiratory Stimuli in Healthy Men and Women During Wakefulness ⬇️

scientific article published on October 1, 2010

An Integrative Model of Physiological Traits Can be Used to Predict Obstructive Sleep Apnea and Response to Non Positive Airway Pressure Therapy.

scientific article published on June 2015

An automated and reliable method for breath detection during variable mask pressures in awake and sleeping humans

scientific article

Arousal Intensity is a Distinct Pathophysiological Trait in Obstructive Sleep Apnea

scientific article published on 20 October 2016

Arousal from sleep does not lead to reduced dilator muscle activity or elevated upper airway resistance on return to sleep in healthy individuals

scientific article

Arousal from sleep: implications for obstructive sleep apnea pathogenesis and treatment.

scientific article published on 29 August 2013

Blunted sensation of dyspnoea and near fatal asthma

scientific article published on 01 August 2004

Breath-to-breath reflex modulation of genioglossus muscle activity in obstructive sleep apnea.

scientific article published on 18 February 2016

Cardiac changes during arousals from non-REM sleep in healthy volunteers

scientific article published on 16 November 2006

Central apnea and decreased drive to upper airway motoneurons during high flow nasal cannula therapy

scientific article published on 25 January 2020

Central sleep apnea in multiple sclerosis: a pilot study.

scientific article published on 14 December 2016

Central sleep apnea: Pathophysiology and treatment.

scientific article published on February 2007

Changes in pharyngeal collapsibility and genioglossus reflex responses to negative pressure during the respiratory cycle in obstructive sleep apnoea

scientific article published on 15 January 2020

Changes in respiration in NREM sleep in hypercapnic chronic obstructive pulmonary disease

scientific article published on 2 July 2004

Clinical predictors of the respiratory arousal threshold in patients with obstructive sleep apnea.

scientific article

Cognitive behavioural therapy for insomnia reduces sleep apnoea severity: a randomised controlled trial

scientific article published on 01 April 2020

Combination therapy with mandibular advancement and expiratory positive airway pressure valves reduces obstructive sleep apnea severity

scientific article published on 01 August 2019

Common drive in hypoglossal and trigeminal motor neurons

scientific article

Concomitant benzodiazepine and opioids decrease sleep apnoea risk in chronic pain patients

scientific article published on 01 July 2020

Critical closing pressure during midazolam-induced sleep.

scientific article published on 18 August 2011

Defining phenotypic causes of obstructive sleep apnea. Identification of novel therapeutic targets.

scientific article published on October 2013

Definition, discrimination, diagnosis and treatment of central breathing disturbances during sleep.

scientific article published on 5 December 2016

Desipramine Increases Genioglossus Activity and Reduces Upper Airway Collapsibility during Non-REM Sleep in Healthy Subjects

scientific article published on 11 March 2016

Desipramine improves upper airway collapsibility and reduces OSA severity in patients with minimal muscle compensation

scientific article published on 6 October 2016

Discharge patterns of human tensor palatini motor units during sleep onset.

scientific article published in May 2012

Dose-dependent effects of mandibular advancement on upper airway collapsibility and muscle function in obstructive sleep apnea

scientific article published on 01 June 2019

Drug effects on ventilatory control and upper airway physiology related to sleep apnea.

scientific article published on 16 May 2013

Effect of 1 month of zopiclone on obstructive sleep apnoea severity and symptoms: a randomised controlled trial

scientific article published on 19 July 2018

Effect of 4-Aminopyridine on Genioglossus Muscle Activity during Sleep in Healthy Adults

scientific article

Effects of Tiagabine on Slow Wave Sleep and Arousal Threshold in Patients With Obstructive Sleep Apnea

scientific article

Effects of hypoxia on genioglossus and scalene reflex responses to brief pulses of negative upper-airway pressure during wakefulness and sleep in healthy men.

scientific article published on 21 February 2008

Effects of inhaled fluticasone on upper airway during sleep and wakefulness in asthma: a pilot study

scientific article published on 15 February 2014

Effects of low-dose morphine on perceived sleep quality in patients with refractory breathlessness: A hypothesis generating study

scientific article published on 12 November 2015

Effects of morphine on respiratory load detection, load magnitude perception and tactile sensation in obstructive sleep apnea.

scientific article published on 26 April 2018

Enhanced upper-airway muscle responsiveness is a distinct feature of overweight/obese individuals without sleep apnea

scientific article

Eszopiclone increases the respiratory arousal threshold and lowers the apnoea/hypopnoea index in obstructive sleep apnoea patients with a low arousal threshold ⬇️

scientific article published on June 1, 2011

Extended-Release Morphine for Chronic Breathlessness in Pulmonary Arterial Hypertension-A Randomized, Double-Blind, Placebo-Controlled, Crossover Study

scientific article published on 19 July 2018

Functional role of neural injury in obstructive sleep apnea ⬇️

scientific article published on June 15, 2012

Genioglossus reflex inhibition to upper-airway negative-pressure stimuli during wakefulness and sleep in healthy males

scientific article published on 29 March 2007

Genioglossus reflex responses to negative upper airway pressure are altered in people with tetraplegia and obstructive sleep apnoea.

scientific article published on 15 April 2018

High nasal resistance is stable over time but poorly perceived in people with tetraplegia and obstructive sleep apnoea

scientific article

Hypoxia suppresses symptom perception in asthma

scientific article published on 12 March 2004

Influence of pharyngeal muscle activity on inspiratory negative effort dependence in the human upper airway.

scientific article

Inspiratory pre-motor potentials during quiet breathing in ageing and chronic obstructive pulmonary disease

scientific article published on 29 July 2018

Is fluid overload a target to treat sleep disordered breathing in patients with end-stage renal disease, and what are the underlying mechanisms?

scientific article

Isolating peripheral effects of endogenous opioids in modulating exertional breathlessness in people with moderate or severe COPD: a randomised controlled trial

scientific article published on 01 October 2019

Mechanisms contributing to the response of upper-airway muscles to changes in airway pressure

scientific article

Mild Airflow Limitation during N2 Sleep Increases K-complex Frequency and Slows Electroencephalographic Activity.

scientific article published on 19 November 2015

Morphine alters respiratory control but not other key OSA phenotypes: A randomised trial

scientific article published on 12 March 2020

Nasal Resistance Is Elevated in People with Tetraplegia and Is Reduced by Topical Sympathomimetic Administration

scientific article published on 22 August 2016

Neurogenic changes in the upper airway of patients with obstructive sleep apnea.

scientific article published on 20 October 2011

New insights into the timing and potential mechanisms of respiratory-induced cortical arousals in obstructive sleep apnea

scientific article published on 01 November 2018

Nocturnal swallowing augments arousal intensity and arousal tachycardia

scientific article published on 30 March 2020

Obstructive Sleep Apnea without Obesity Is Common and Difficult to Treat: Evidence for a Distinct Pathophysiological Phenotype

scientific article published on 13 September 2016

Obstructive sleep apnea in older adults is a distinctly different physiological phenotype

scientific article

Obstructive sleep apnea: current perspectives.

scientific article published on 23 January 2018

Obstructive sleep apnoea pathogenesis from mild to severe: Is it all the same?

scientific article

Pathophysiology of adult obstructive sleep apnea.

scientific article published on February 2008

Personalized Management Approach for OSA.

scientific article

Phenotypic approach to pharmacotherapy in the management of obstructive sleep apnoea

scientific article published on 01 November 2019

Phenotypic approaches to obstructive sleep apnoea - New pathways for targeted therapy.

scientific article published on 18 December 2016

Phenotypic approaches to positional therapy for obstructive sleep apnoea.

scientific article published on 23 June 2017

Polysomnographic Endotyping to Select Patients with Obstructive Sleep Apnea for Oral Appliances

scientific article published on 01 November 2019

Polysomnography with an epiglottic pressure catheter does not alter obstructive sleep apnea severity or sleep efficiency

scientific article published on 01 October 2018

Qualitative Phenotyping of Obstructive Sleep Apnea and Its Clinical Usefulness for the Sleep Specialist

scientific article published on 20 March 2020

Quantifying the ventilatory control contribution to sleep apnoea using polysomnography

scientific article

Reboxetine and hyoscine butylbromide improve upper airway function during nonrapid eye movement and suppress rapid eye movement sleep in healthy individuals

scientific article published on 01 April 2019

Recruitment and rate-coding strategies of the human genioglossus muscle ⬇️

scientific article published on October 14, 2010

Regional respiratory movement of the tongue is coordinated during wakefulness and is larger in severe obstructive sleep apnoea

scientific article published on 16 January 2020

Reply: Arousal threshold in obstructive sleep apnea

scientific article published on February 2014

Reply: Is the Muscle the Only Potential Target of Desipramine in Obstructive Sleep Apnea Syndrome?

scientific article

Respiratory-related displacement of the trachea in obstructive sleep apnea

scientific article published on 12 September 2019

Role of common hypnotics on the phenotypic causes of obstructive sleep apnoea: paradoxical effects of zolpidem

scientific article published on 28 December 2017

Sensorimotor function of the upper-airway muscles and respiratory sensory processing in untreated obstructive sleep apnea.

scientific article published on September 2011

Sitting and supine esophageal pressures in overweight and obese subjects

scientific article

Sleep-Disordered Breathing in People with Multiple Sclerosis: Prevalence, Pathophysiological Mechanisms, and Disease Consequences

scientific article published in January 2017

Stable breathing through deeper sleeping.

scientific article published in February 2010

Sustained hypoxia depresses sensory processing of respiratory resistive loads.

scientific article published on 23 June 2005

Termination of Respiratory Events with and without Cortical Arousal in Obstructive Sleep Apnea ⬇️

scientific article published on August 11, 2011

The Combination of Atomoxetine and Oxybutynin Greatly Reduces Obstructive Sleep Apnea Severity: A Randomized, Placebo-Controlled, Double-Blind Crossover Trial

scientific article published on 01 May 2019

The Combination of Supplemental Oxygen and a Hypnotic Markedly Improves Obstructive Sleep Apnea in Patients with a Mild to Moderate Upper Airway Collapsibility.

scientific article published on 09 September 2016

The Effect of Hypopnea Scoring on the Arousal Threshold in Patients with Obstructive Sleep Apnea

scientific article published on 18 June 2020

The classical Starling resistor model often does not predict inspiratory airflow patterns in the human upper airway

scientific article

The effect of acute morphine on obstructive sleep apnoea: a randomised double-blind placebo-controlled crossover trial

scientific article published on 30 August 2018

The effects of hypoxia on load compensation during sustained incremental resistive loading in patients with obstructive sleep apnea

scientific article published on 5 April 2007

The effects of zolpidem in obstructive sleep apnea - An open-label pilot study

scientific article published on 10 April 2019

The human upper airway: more than a floppy tube

scientific article published on 19 December 2013

The influence of end-expiratory lung volume on measurements of pharyngeal collapsibility. ⬇️

scientific article

The influence of obstructive sleep apnea and gender on genioglossus activity during rapid eye movement sleep.

scientific article published on 31 December 2008

Therapeutic CPAP Level Predicts Upper Airway Collapsibility in Patients With Obstructive Sleep Apnea

scientific article published on 13 April 2017

Trazodone increases the respiratory arousal threshold in patients with obstructive sleep apnea and a low arousal threshold

scientific article

Treating Obstructive Sleep Apnea with Hypoglossal Nerve Stimulation ⬇️

scientific article published on November 1, 2011

Upper Airway Collapsibility (Pcrit) and Pharyngeal Dilator Muscle Activity are Sleep Stage Dependent

scientific article published on 19 November 2015

Upper airway collapsibility is associated with obesity and hyoid position

scientific article

Upper airway collapsibility measured using a simple wakefulness test closely relates to the pharyngeal critical closing pressure during sleep in obstructive sleep apnea

scientific article published on 01 July 2019

Ventilatory Response to Brief Arousal from Non–Rapid Eye Movement Sleep Is Greater in Men Than in Women ⬇️

scientific article published on October 2, 2003

When insulin has to work hard to keep the sugar at bay the upper airway collapses away

scientific article published on 01 June 2016

Zolpidem increases sleep efficiency and the respiratory arousal threshold without changing sleep apnoea severity and pharyngeal muscle activity

scientific article published on 30 August 2020

Zopiclone Increases the Arousal Threshold without Impairing Genioglossus Activity in Obstructive Sleep Apnea.

scientific article published on 22 December 2015

[Pathophysiology of obstructive sleep apnea]

scientific article published on 01 September 2019

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