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List of works by Rafael Fonseca

6q deletion in Waldenström macroglobulinemia is associated with features of adverse prognosis

scientific article published on 01 January 2007

A comparison of lenalidomide/dexamethasone versus cyclophosphamide/lenalidomide/dexamethasone versus cyclophosphamide/bortezomib/dexamethasone in newly diagnosed multiple myeloma

scientific article

A novel measure of chromosome instability can account for prognostic difference in multiple myeloma

scientific article

A novel report of cig-FISH and cytogenetics in POEMS syndrome.

scientific article

A phase I study of 153Sm-EDTMP with fixed high-dose melphalan as a peripheral blood stem cell conditioning regimen in patients with multiple myeloma

scientific article published in January 2005

A phase II trial of imatinib in patients with refractory/relapsed myeloma

scientific article published on January 2006

A pilot program in collaboration with African American churches successfully increases awareness of the importance of cancer research and participation in cancer translational research studies among African Americans.

scientific article published on June 2012

A practical guide to defining high-risk myeloma for clinical trials, patient counseling and choice of therapy

scientific article published on 18 January 2007

AID-dependent activation of a MYC transgene induces multiple myeloma in a conditional mouse model of post-germinal center malignancies.

scientific article published in February 2008

Absence of tissue factor expression by neoplastic plasma cells in multiple myeloma

scientific article

Acquired Fanconi syndrome is an indolent disorder in the absence of overt multiple myeloma

scientific article published on 9 March 2004

Activity of pomalidomide in patients with immunoglobulin light-chain amyloidosis

scientific article

An integrated genomic and expression analysis of 7q deletion in splenic marginal zone lymphoma

scientific article

Analysis of genetic abnormalities provides insights into genetic evolution of hyperdiploid myeloma

article

Anemia After Orchiectomy

article

Assessing Patient-Reported Financial Hardship in Patients With Cancer in Routine Clinical Care

Association of Clinical Researchers and Educators a statement on relationships between physicians and industry

scientific article published in November 2012

Biologic and genetic characterization of the novel amyloidogenic lambda light chain-secreting human cell lines, ALMC-1 and ALMC-2.

scientific article

Bone marrow angiogenesis in multiple myeloma: effect of therapy

article

Cell lines of hyperdiploid myeloma, are we there yet?

scientific article published on 19 November 2007

Centrosomes and myeloma; aneuploidy and proliferation.

scientific article published on October 2009

Cereblon expression is required for the antimyeloma activity of lenalidomide and pomalidomide.

scientific article

Chromosomal abnormalities in systemic amyloidosis

article

Chromosome 1q21 abnormalities in multiple myeloma

Chromosome abnormalities clustering and its implications for pathogenesis and prognosis in myeloma

scientific article published on 01 February 2003

Circulating peripheral blood plasma cells as a prognostic indicator in patients with primary systemic amyloidosis

scientific article published on 05 September 2002

Clarithromycin (Biaxin)-lenalidomide-low-dose dexamethasone (BiRd) versus lenalidomide-low-dose dexamethasone (Rd) for newly diagnosed myeloma

scientific article

Clinical Course and Prognosis of Smoldering (Asymptomatic) Multiple Myeloma

article

Clinical and biologic implications of recurrent genomic aberrations in myeloma

scientific article published on 6 February 2003

Clinical and biological implications of MYC activation: a common difference between MGUS and newly diagnosed multiple myeloma.

scientific article

Clinical and biological significance of RAS mutations in multiple myeloma.

scientific article

Clinicopathological definition of Waldenstrom's macroglobulinemia: consensus panel recommendations from the Second International Workshop on Waldenstrom's Macroglobulinemia

scientific article

Clonal competition with alternating dominance in multiple myeloma.

scientific article

Combination therapy with thalidomide plus dexamethasone for newly diagnosed myeloma

scientific article published in November 2002

Combining fluorescent in situ hybridization data with ISS staging improves risk assessment in myeloma: an International Myeloma Working Group collaborative project

scientific article

Compromised stem cell mobilization following induction therapy with lenalidomide in myeloma.

scientific article published on 24 January 2008

Conflicts of interest, authorship, and disclosures in industry-related scientific publications

scientific article

Consensus recommendations for risk stratification in multiple myeloma: report of the International Myeloma Workshop Consensus Panel 2.

scientific article published on 03 February 2011

Consolidation therapy with bortezomib/lenalidomide/ dexamethasone versus bortezomib/dexamethasone after a dexamethasone-based induction regimen in patients with multiple myeloma: a randomized phase III trial

scientific article

Content development for the Functional Assessment of Cancer Therapy-Multiple Myeloma (FACT-MM): use of qualitative and quantitative methods for scale construction

scientific article

Correlation between array-comparative genomic hybridization-defined genomic gains and losses and survival: identification of 1p31-32 deletion as a prognostic factor in myeloma

scientific article

Cyclophosphamide, bortezomib and dexamethasone induction for newly diagnosed multiple myeloma: high response rates in a phase II clinical trial.

scientific article

Cyclophosphamide-bortezomib-dexamethasone (CyBorD) produces rapid and complete hematologic response in patients with AL amyloidosis.

scientific article published on 13 February 2012

Cytogenetic Abnormalities Correlate with the Plasma Cell Labeling Index and Extent of Bone Marrow Involvement in Myeloma

article

DNA Methylation Analysis Determines the High Frequency of Genic Hypomethylation and Low Frequency of Hypermethylation Events in Plasma Cell Tumors

article

DNA methylation in multiple myeloma is weakly associated with gene transcription

scientific article

Deletions of 17p13.1 and 13q14 are uncommon in Waldenström macroglobulinemia clonal cells and mostly seen at the time of disease progression

article

Deletions of chromosome 13 in multiple myeloma identified by interphase FISH usually denote large deletions of the q arm or monosomy.

scientific article

Detection of diagnostically critical, often hidden, anomalies in complex karyotypes of haematological disorders using multicolour fluorescence in situ hybridization

scientific article published on 01 March 2001

Diagnosis and management of Waldenström macroglobulinemia: Mayo stratification of macroglobulinemia and risk-adapted therapy (mSMART) guidelines

scientific article

Diagnostic evaluation of t(4;14) in multiple myeloma and evidence for clonal evolution.

scientific article published on 14 June 2007

Dissecting karyotypic patterns in non-hyperdiploid multiple myeloma: an overview on the karyotypic evolution

scientific article published on 12 July 2013

Do beta2 microglobulin levels affect survival of newly diagnosed myeloma patients with translocation t(4;14) or 17p13 deletion treated with conventional chemotherapy?

scientific article published on 29 November 2007

Downregulation of specific miRNAs in hyperdiploid multiple myeloma mimics the oncogenic effect of IgH translocations occurring in the non-hyperdiploid subtype.

scientific article published on 22 October 2012

Economic burden of disease progression among multiple myeloma patients who have received transplant and at least one line of therapy in the US

Effect of thalidomide therapy on bone marrow angiogenesis in multiple myeloma.

scientific article published in March 2004

Effect of tissue shipping on plasma cell isolation, viability, and RNA integrity in the context of a centralized good laboratory practice-certified tissue banking facility

scientific article

Establishment and characterization of a novel Waldenstrom macroglobulinemia cell line, MWCL-1.

scientific article published on 17 March 2011

Evidence for cytogenetic and fluorescence in situ hybridization risk stratification of newly diagnosed multiple myeloma in the era of novel therapie

scientific article

Expression and mutation status of candidate kinases in multiple myeloma

scientific article published on 08 March 2007

Expression of VEGF and its receptors by myeloma cells

scientific article published on 01 October 2003

Farnesyltransferase inhibitor tipifarnib is well tolerated, induces stabilization of disease, and inhibits farnesylation and oncogenic/tumor survival pathways in patients with advanced multiple myeloma

scientific article (publication date: May 2004)

Follicular dendritic cell sarcoma and interdigitating reticulum cell sarcoma: A review ⬇️

scientific article published on October 1, 1998

Follicular dendritic cell sarcoma mimicking diffuse large cell lymphoma: A case report ⬇️

scientific article published on July 1, 1997

Frontline treatment of multiple myeloma ⬇️

scientific article published on 01 April 2012

Functional gene expression analysis of clonal plasma cells identifies a unique molecular profile for light chain amyloidosis

article

Gene expression profiling of pulmonary mucosa-associated lymphoid tissue lymphoma identifies new biologic insights with potential diagnostic and therapeutic applications

scientific article published on 30 October 2008

Genetics and cytogenetics of Waldenstrom's macroglobulinemia

article

Genetics and cytogenetics of multiple myeloma: a workshop report

scientific article published in February 2004

Genetics of multiple myeloma.

scientific article

Genome-wide analysis reveals recurrent structural abnormalities of TP63 and other p53-related genes in peripheral T-cell lymphomas.

scientific article

Genome-wide characterization of pancreatic adenocarcinoma patients using next generation sequencing

scientific article

Genomic abnormalities of Waldenström macroglobulinemia and related low-grade B-cell lymphomas

scientific article

Genomic analysis of marginal zone and lymphoplasmacytic lymphomas identified common and disease-specific abnormalities

scientific article published on 3 February 2012

Genomics and proteomics in multiple myeloma and Waldenström macroglobulinemia.

scientific article published on July 2007

Genomics in multiple myeloma: biology and clinical implications.

scientific article

High-dose therapy and autologous stem cell transplantation for multiple myeloma poorly responsive to initial therapy

scientific article

High-resolution genomic analysis in Waldenström's macroglobulinemia identifies disease-specific and common abnormalities with marginal zone lymphomas

scientific article (publication date: March 2009)

High-throughput genomic analysis in Waldenström's macroglobulinemia

scientific article published on February 2011

How Physicians Interpret Research Funding Disclosures ⬇️

scientific article published on December 13, 2012

Hypodiploid multiple myeloma is characterized by more aggressive molecular markers than non-hyperdiploid multiple myeloma.

scientific article published on 28 May 2013

IGF-1R is overexpressed in poor-prognostic subtypes of multiple myeloma

scientific article published on 01 January 2006

IMWG consensus on risk stratification in multiple myeloma

scientific article published on 26 August 2013

Identification of copy number abnormalities and inactivating mutations in two negative regulators of nuclear factor-kappaB signaling pathways in Waldenstrom's macroglobulinemia

scientific article (publication date: 15 April 2009)

Identification of genes modulated in multiple myeloma using genetically identical twin samples

scientific article published on 11 September 2003

Identification of kinetin riboside as a repressor of CCND1 and CCND2 with preclinical antimyeloma activity

scientific article

Impact of Disease Progression, Line of Therapy, and Response on Health-Related Quality of Life in Multiple Myeloma: A Systematic Literature Review

Impact of gene expression profiling-based risk stratification in patients with myeloma receiving initial therapy with lenalidomide and dexamethasone

scientific article

Impact of high-risk classification by FISH: an eastern cooperative oncology group (ECOG) study E4A03.

scientific article

Impact of primary molecular cytogenetic abnormalities and risk of progression in smoldering multiple myeloma

scientific article published on 21 March 2013

Impact of risk stratification on outcome among patients with multiple myeloma receiving initial therapy with lenalidomide and dexamethasone

scientific article published on 26 March 2009

Initial genome sequencing and analysis of multiple myeloma

scientific article

Initial immunoglobulin M ?flare? after rituximab therapy in patients diagnosed with Waldenstrom macroglobulinemia

scientific article published on 01 December 2004

Innovation in myeloma treatments PARP excellence! ⬇️

scientific article published on December 8, 2011

International Myeloma Working Group molecular classification of multiple myeloma: spotlight review.

scientific article

Kinome-wide RNAi studies in human multiple myeloma identify vulnerable kinase targets, including a lymphoid-restricted kinase, GRK6.

scientific article

Lenalidomide plus dexamethasone versus thalidomide plus dexamethasone in newly diagnosed multiple myeloma: a comparative analysis of 411 patients

scientific article

Lenalidomide plus high-dose dexamethasone versus lenalidomide plus low-dose dexamethasone as initial therapy for newly diagnosed multiple myeloma: an open-label randomised controlled trial

scientific article

Lenalidomide, cyclophosphamide and dexamethasone (CRd) for newly diagnosed multiple myeloma: results from a phase 2 trial

scientific article published on 31 May 2011

Lenalidomide, cyclophosphamide, and dexamethasone (CRd) for light-chain amyloidosis: long-term results from a phase 2 trial

scientific article

Lessons from next-generation sequencing analysis in hematological malignancies.

scientific article published on 19 July 2013

Long-term results of response to therapy, time to progression, and survival with lenalidomide plus dexamethasone in newly diagnosed myeloma

scientific article published in October 2007

Long-term results of the treatment of patients with mantle cell lymphoma with cladribine (2-CDA) alone (95-80-53) or 2-CDA and rituximab (N0189) in the North Central Cancer Treatment Group.

scientific article

Longitudinal genome-wide analysis of patients with chronic lymphocytic leukemia reveals complex evolution of clonal architecture at disease progression and at the time of relapse.

scientific article published on 20 January 2012

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines

scientific article published on December 2009

Management of newly diagnosed symptomatic multiple myeloma: updated Mayo Stratification of Myeloma and Risk-Adapted Therapy (mSMART) consensus guidelines 2013.

scientific article published on April 2013

Many and multiple myeloma(s) ⬇️

scientific article published on October 1, 2003

MicroRNA expression in tumor cells from Waldenstrom's macroglobulinemia reflects both their normal and malignant cell counterparts.

scientific article published on 17 June 2011

Molecular Dissection of Hyperdiploid Multiple Myeloma by Gene Expression Profiling

article

Molecular pathogenesis of Waldenstrom's macroglobulinemia.

scientific article published on 06 July 2012

Monoclonal gammopathy of undetermined significance does not affect outcomes in patients undergoing solid organ transplants

scientific article published in September 2011

Monoclonal gammopathy of undetermined significance: a consensus statement

scientific article

Multiple myeloma and the translocation t(11;14)(q13;q32): a report on 13 cases

scientific article published in May 1998

Myeloma and the t(11;14)(q13;q32); evidence for a biologically defined unique subset of patients.

scientific article

Myeloma in patients younger than age 50 years presents with more favorable features and shows better survival: an analysis of 10 549 patients from the International Myeloma Working Group

scientific article

Myeloma: classification and risk assessment.

scientific article published on October 2013

Once- versus twice-weekly bortezomib induction therapy with CyBorD in newly diagnosed multiple myeloma.

scientific article published in April 2010

POEMS syndrome: definitions and long-term outcome

scientific article

Phase I, pharmacokinetic and pharmacodynamic study of the anti-insulinlike growth factor type 1 Receptor monoclonal antibody CP-751,871 in patients with multiple myeloma

scientific article

Phase II trial of single-agent temsirolimus (CCI-779) for relapsed mantle cell lymphoma

scientific article

Phase III clinical trial of thalidomide plus dexamethasone compared with dexamethasone alone in newly diagnosed multiple myeloma: a clinical trial coordinated by the Eastern Cooperative Oncology Group

scientific article published on 19 December 2005

Plasma cell leukemia

scientific article

Plasma cell leukemia: consensus statement on diagnostic requirements, response criteria and treatment recommendations by the International Myeloma Working Group

scientific article

Plasma levels of tumour necrosis factor alpha and interleukin-6 predict progression-free survival following thalidomide therapy in patients with previously untreated multiple myeloma

scientific article published in October 2003

Ploidy status rarely changes in myeloma patients at disease progression.

scientific article

Pomalidomide (CC4047) plus low dose dexamethasone (Pom/dex) is active and well tolerated in lenalidomide refractory multiple myeloma (MM).

scientific article

Pomalidomide (CC4047) plus low-dose dexamethasone as therapy for relapsed multiple myeloma

scientific article

Pomalidomide plus low-dose dexamethasone in myeloma refractory to both bortezomib and lenalidomide: comparison of 2 dosing strategies in dual-refractory disease

scientific article published on 20 June 2011

Prediction of immunomodulatory drugs (IMiDs) sensitivity in myeloma via determination of baseline anti-oxidative stress capacity

scientific article published on 05 June 2020

Prevalence and risk of progression of light-chain monoclonal gammopathy of undetermined significance: a retrospective population-based cohort study

scientific article

Primary central nervous system lymphomas: a validation study of array-based comparative genomic hybridization in formalin-fixed paraffin-embedded tumor specimens

scientific article

Primary plasma cell leukemia: report of 17 new cases treated with autologous or allogeneic stem-cell transplantation and review of the literature

scientific article

Primary therapy with single agent bortezomib as induction, maintenance and re-induction in patients with high-risk myeloma: results of the ECOG E2A02 trial.

scientific article

Prognostic and therapeutic significance of myeloma genetics and gene expression profiling.

scientific article

Prognostic factors for hyperdiploid-myeloma: effects of chromosome 13 deletions and IgH translocations

scientific article

Prognostic model for disease-specific and overall mortality in newly diagnosed symptomatic patients with Waldenstrom macroglobulinaemia

scientific article

Prognostic value of angiogenesis in solitary bone plasmacytoma

scientific article published on 17 October 2002

Prognostic value of bone marrow angiogenesis in patients with multiple myeloma undergoing high-dose therapy.

scientific article published in August 2004

Prognostic value of chromosome 1q21 gain by fluorescent in situ hybridization and increase CKS1B expression in myeloma

scientific article published on 05 October 2006

Prognostic value of serum markers of bone metabolism in untreated multiple myeloma patients

article

Progressive but previously untreated CLL patients with greater array CGH complexity exhibit a less durable response to chemoimmunotherapy

scientific article

Promiscuous mutations activate the noncanonical NF-kappaB pathway in multiple myeloma.

scientific article

Proteomic Analysis of Waldenstrom Macroglobulinemia

article

Recurrent Chromosome Abnormalities Define Nonoverlapping Unique Subgroups of Tumors in Patients With Chronic Lymphocytic Leukemia and Known Karyotypic Abnormalities

scientific article published on 01 August 2013

Relationship between elevated immunoglobulin free light chain and the presence of IgH translocations in multiple myeloma

scientific article published on 3 June 2010

Relationship of patient survival and chromosome anomalies detected in metaphase and/or interphase cells at diagnosis of myeloma.

scientific article published on 19 July 2005

Review of molecular diagnostics in multiple myeloma.

scientific article published on July 2007

Risk stratification of patients with newly diagnosed multiple myeloma: optimizing treatment based on pretreatment characteristics.

scientific article

Selective serotonin reuptake inhibitors are effective in the treatment of polycythemia vera-associated pruritus

scientific article

Single agent dexamethasone for pre-stem cell transplant induction therapy for multiple myeloma

scientific article published on 01 September 2004

Smoldering multiple myeloma requiring treatment: time for a new definition?

scientific article

Spontaneous remission in a patient with t(4;14) translocation multiple myeloma

scientific article published on 05 October 2009

Targeting TMPRSS2 in SARS-CoV-2 Infection

scientific article published on 19 July 2020

Testicular lymphoma is associated with a high incidence of extranodal recurrence

scientific article published on 01 January 2000

Thalidomide as initial therapy for early-stage myeloma

scientific article published in April 2003

The (11;14)(q13;q32) Translocation in Multiple Myeloma

scientific article published on 01 June 2000

The Case of the Phantom Bladder

scientific article published on 01 April 1997

The MYDas touch of next-gen sequencing

scientific article published in March 2013

The centrosome index is a powerful prognostic marker in myeloma and identifies a cohort of patients that might benefit from aurora kinase inhibition

scientific article published on 15 November 2007

The clinical significance of cereblon expression in multiple myeloma

scientific article published on 05 September 2013

The t(4;14)(p16.3;q32) is strongly associated with chromosome 13 abnormalities in both multiple myeloma and monoclonal gammopathy of undetermined significance

article

Thrombosis in multiple myeloma (MM).

scientific article published on April 2012

Transfusion-dependent anemia after initiation of androgen deprivation therapy for metastatic prostate cancer

scientific article published in October 2007

Translocation t(11;14) and survival of patients with light chain (AL) amyloidosis.

scientific article published on 11 February 2009

Translocation t(4;14) retains prognostic significance even in the setting of high-risk molecular signature

scientific article published on 6 September 2007

Translocations involving the immunoglobulin heavy-chain locus are possible early genetic events in patients with primary systemic amyloidosis

scientific article published on 01 October 2001

Treatment with bortezomib of a patient having hyper IgG4 disease

scientific article published in June 2010

Trisomies in multiple myeloma: impact on survival in patients with high-risk cytogenetics

scientific article published on 10 January 2012

Tumor suppressor p16 methylation in multiple myeloma: biological and clinical implications

scientific article published on 13 July 2006

Uncovering the biology of multiple myeloma among African Americans: a comprehensive genomics approach

scientific article published on 19 February 2013

Unraveling the multiple myeloma genome in the next-generation sequencing era: challenges to translating knowledge into the clinic

scientific article published on 01 December 2011

Waldenström macroglobulinaemia

scientific article published on 2 August 2007

Waldenström macroglobulinaemia.

scientific article published on November 2003

Whole-genome sequencing of multiple myeloma from diagnosis to plasma cell leukemia reveals genomic initiating events, evolution, and clonal tides

scientific article

t(4;14)(p16.3;q32) is strongly associated with a shorter survival in myeloma patients.

scientific article

t(X;14)(p11;q32) in MALT lymphoma involving GPR34 reveals a role for GPR34 in tumor cell growth.

scientific article

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