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List of works by Jörn Lötsch

A Data Science-Based Analysis Points at Distinct Patterns of Lipid Mediator Plasma Concentrations in Patients With Dementia

scientific article published on 11 February 2019

A Data-Driven Approach to Responder Subgroup Identification after Paired Continuous Theta Burst Stimulation

scientific article

A GTP cyclohydrolase 1 genetic variant delays cancer pain

scientific article

A KCNJ6 (Kir3.2, GIRK2) gene polymorphism modulates opioid effects on analgesia and addiction but not on pupil size

scientific article published in May 2010

A brain-lesion pattern based algorithm for the diagnosis of posttraumatic olfactory loss

scientific article published in December 2015

A common HLA-DPA1 variant is associated with hepatitis B virus infection but fails to distinguish active from inactive Caucasian carriers

scientific article published on 20 March 2012

A common human micro-opioid receptor genetic variant diminishes the receptor signaling efficacy in brain regions processing the sensory information of pain

scientific article

A critical appraisal of human genotyping for pain therapy

scientific article published on 17 May 2010

A data science approach to candidate gene selection of pain regarded as a process of learning and neural plasticity.

scientific article

A data science based standardized Gini index as a Lorenz dominance preserving measure of the inequality of distributions

scientific article published on 10 August 2017

A machine-learned analysis of human gene polymorphisms modulating persisting pain points to major roles of neuroimmune processes

article

A machine-learned analysis suggests non-redundant diagnostic information in olfactory subtests

scientific article published on 07 January 2019

A machine-learned computational functional genomics-based approach to drug classification

scientific article published on October 2016

A machine-learned knowledge discovery method for associating complex phenotypes with complex genotypes. Application to pain.

scientific article published on 27 July 2013

A more pessimistic life orientation is associated with experimental inducibility of a neuropathy-like pain pattern in healthy individuals

scientific article

A non-parametric effect-size measure capturing changes in central tendency and data distribution shape

scientific article published on 24 September 2020

A rapid screening method for a single nucleotide polymorphism (SNP) in the human MOR gene

scientific article published on December 2001

A short olfactory test based on the identification of three odors

scientific article published on 16 March 2010

A simple and reliable method for clinical assessment of odor thresholds

scientific article

A small yet comprehensive subset of human experimental pain models emerging from correlation analysis with a clinical quantitative sensory testing protocol in healthy subjects

scientific article published on 22 October 2015

Abuse-Deterrent Opioid Formulations: Pharmacokinetic and Pharmacodynamic Considerations.

scientific article published on 30 December 2015

Agreeable smellers and sensitive neurotics--correlations among personality traits and sensory thresholds

scientific article

Analgesic Effects of Dihydrocodeine and Tramadol when Administered Either in the Morning or Evening

scientific article published on 01 February 1995

Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers

scientific article

Analgesic effects of propyphenazone in comparison to its combination with caffeine

scientific article published on 01 January 1996

Analgesic efficacy of tramadol, pregabalin and ibuprofen in menthol-evoked cold hyperalgesia

scientific article published on 16 September 2009

Antinociceptive effects of morphine-6-glucuronide in homozygous MDR1a P-glycoprotein knockout and in wildtype mice in the hotplate test

scientific article published on May 2000

Antinociceptive effects of the kappa-opioid receptor agonist RP 60180 compared with pentazocine in an experimental human pain model.

scientific article published on June 1997

Are mu-opioid receptor polymorphisms important for clinical opioid therapy?

scientific article

Association of cyclophosphamide pharmacokinetics to polymorphic cytochrome P450 2C19

scientific article published in January 2005

Association of genetic and psychological factors with persistent pain after cosmetic thoracic surgery

scientific article

Association of saquinavir plasma concentrations with side effects but not with antiretroviral outcome in patients infected with protease inhibitor-susceptible human immunodeficiency virus type 1

scientific article

Basic Genetic Statistics Are Necessary in Studies of Functional Associations in Anesthesiology

scientific article published on 01 July 2007

Bedside-to-bench pharmacology: a complementary concept to translational pharmacology

scientific article published in June 2010

Bilateral hyperalgesia to chemical stimulation of the nasal mucosa following unilateral inflammation

scientific article published on 01 December 1997

Bioequivalence criteria for transdermal fentanyl generics: do these need a relook?

scientific article published on January 2009

Brain Mapping-Based Model of Δ(9)-Tetrahydrocannabinol Effects on Connectivity in the Pain Matrix

scientific article published on 30 October 2015

Brain lesion-pattern analysis in patients with olfactory dysfunctions following head trauma

scientific article published on 21 January 2016

Can extremely low or high morphine formation from codeine be predicted prior to therapy initiation?

scientific article published on 22 April 2009

Cannabinoid-related olfactory neuroscience in mice and humans

scientific article published on 11 November 2014

Capsaicin or menthol sensitization induces quantitative but no qualitative changes to thermal and mechanical pain thresholds

scientific article published on February 2009

Central encoding of the strength of intranasal chemosensory trigeminal stimuli in a human experimental pain setting

scientific article published on 01 September 2020

Ceramide synthases and ceramide levels are increased in breast cancer tissue

scientific article

Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain

scientific article

Chronobiology of Nasal Chemosensitivity: Do Odor or Trigeminal Pain Thresholds Follow a Circadian Rhythm?

scientific article published on 01 October 1997

Circadian rhythm and desensitization in chemosensory event-related potentials in response to odorous and painful stimuli

scientific article published in July 2003

Clinical Significance of Results from Olfactory Testing

scientific article published on 01 October 2006

Clinical Usefulness of Self-Rated Olfactory Performance-A Data Science-Based Assessment of 6000 Patients

scientific article published on 01 July 2019

Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk

scientific article published on 26 April 2008

Clinical pharmacology of analgesics assessed with human experimental pain models: bridging basic and clinical research

scientific article

Clinical pharmacology of morphine and morphine-6-glucuronide. A PK/PD modeling approach

scholarly article by Jörn Lötsch published August 2001 in International Congress Series

Common non-epigenetic drugs as epigenetic modulators

scientific article

Comparative clinical effects of hydromorphone and morphine: a meta-analysis

scientific article

Comparison of inhibitory effects of meloxicam and diclofenac on human thromboxane biosynthesis after single doses and at steady state

scientific article published on 01 May 1999

Comparison of tissue concentrations after intramuscular and topical administration of ketoprofen

scientific article

Comparison of two screening methods for in-house genotyping in clinical pharmacology units

scientific article published on 01 January 2005

Comprehensive mu-opioid-receptor genotyping by pyrosequencing

scientific article

Computational functional genomics based analysis of pain-relevant micro-RNAs.

scientific article published on 18 September 2015

Computational functional genomics-based approaches in analgesic drug discovery and repurposing

scientific article published on 24 May 2018

Computational functional genomics-based reduction of disease-related gene sets to their key components

article

Computed ABC Analysis for Rational Selection of Most Informative Variables in Multivariate Data

scientific article

Congenital taurine deficiency in mice is associated with reduced sensitivity to nociceptive chemical stimulation

scientific article published on 7 December 2013

Consequences of a human TRPA1 genetic variant on the perception of nociceptive and olfactory stimuli

scientific article

Correspondence

scientific article published on 01 April 1997

Cross-sectional analysis of the influence of currently known pharmacogenetic modulators on opioid therapy in outpatient pain centers

scientific article

Cross-sectional assessment of the consequences of a GTP cyclohydrolase 1 haplotype for specialized tertiary outpatient pain care

scientific article published in November 2009

Current Projection Methods-Induced Biases at Subgroup Detection for Machine-Learning Based Data-Analysis of Biomedical Data

scientific article published on 20 December 2019

Current evidence for a genetic modulation of the response to analgesics

scientific article

Current evidence for a modulation of low back pain by human genetic variants

scientific article published on 17 February 2009

Current evidence for a modulation of nociception by human genetic polymorphisms

scientific article published on 15 August 2007

Current evidence of cannabinoid-based analgesia obtained in preclinical and human experimental settings

scientific article published on 21 November 2017

Cytochrome P450 3A inhibition by atazanavir and ritonavir, but not demography or drug formulation, influences saquinavir population pharmacokinetics in human immunodeficiency virus type 1-infected adults

scientific article published on 15 June 2009

Cytochrome P450 epoxygenase dependence of opioid analgesia: fluconazole does not interfere with remifentanil-mediated analgesia in human subjects

scientific article published on 22 August 2014

Data visualizations to detect systematic errors in laboratory assay results

scientific article published in December 2017

Decrease of atazanavir and lopinavir plasma concentrations in a boosted double human immunodeficiency virus protease inhibitor salvage regimen

scientific article published on 14 April 2008

Delta-9-tetrahydrocannabinol reduces the performance in sensory delayed discrimination tasks. A pharmacological-fMRI study in healthy volunteers

scientific article published on 13 November 2019

Development of an AmpliSeq Panel for Next-Generation Sequencing of a Set of Genetic Predictors of Persisting Pain

article

Different Odor Tests Contribute Differently to the Evaluation of Olfactory Loss

scientific article published on 30 August 2007

Differential opioid action on sensory and affective cerebral pain processing

scientific article

Disagreement between two common biomarkers of global DNA methylation

scientific article (publication date: 2016)

Distribution Optimization: An evolutionary algorithm to separate Gaussian mixtures

scientific article published on 20 January 2020

Does the A118G polymorphism at the mu-opioid receptor gene protect against morphine-6-glucuronide toxicity?

scientific article published in October 2002

Drug interactions with patient-controlled analgesia

scientific article

Drug-target based cross-sectional analysis of olfactory drug effects

scientific article published on 11 February 2015

Drugs and Epigenetic Molecular Functions. A Pharmacological Data Scientometric Analysis

scientific article published in 2021

Dysregulation of lysophosphatidic acids in multiple sclerosis and autoimmune encephalomyelitis.

scientific article

Effect sizes in experimental pain produced by gender, genetic variants and sensitization procedures

scientific article

Effects of 20 mg oral Δ(9) -tetrahydrocannabinol on the olfactory function of healthy volunteers

scientific article

Effects of ABCB1 (multidrug resistance transporter) gene mutations on disposition and central nervous effects of loperamide in healthy volunteers

scientific article published in November 2003

Effects of Nasal-Airway Volume and Body Temperature on Intranasal Chemosensitivity

scientific article published on 01 February 1998

Effects of azapropazone on pain-related brain activity in human subjects.

scientific article

Effects of continuous theta-burst stimulation of the primary motor and secondary somatosensory areas on the central processing and the perception of trigeminal nociceptive input in healthy volunteers

scientific article published on 01 January 2019

Effects of flurbiprofen enantiomers on pain-related chemo-somatosensory evoked potentials in human subjects

scientific article

Effects of oral Δ9-tetrahydrocannabinol on the cerebral processing of olfactory input in healthy non-addicted subjects

scientific article published on 2 September 2017

Effects of the opioid remifentanil on olfactory function in healthy volunteers.

scientific article published in September 2001

Emergent biomarker derived from next-generation sequencing to identify pain patients requiring uncommonly high opioid doses

scientific article published on 3 May 2016

Epigenetics in pain and analgesia: an imminent research field

scientific article published on 02 July 2010

Event-related potentials to intranasal trigeminal stimuli change in relation to stimulus concentration and stimulus duration

scientific article published in February 2003

Evidence for morphine-independent central nervous opioid effects after administration of codeine: contribution of other codeine metabolites

scientific article published on January 2006

Exogenous delta⁹-tetrahydrocannabinol influences circulating endogenous cannabinoids in humans

scientific article published in October 2013

Exploiting the Structures of the U-Matrix

Extended cortical activations during evaluating successive pain stimuli

scientific article

Factors affecting pain intensity in a pain model based upon tonic intranasal stimulation in humans

scientific article published on 01 November 1998

Fatal respiratory depression after multiple intravenous morphine injections

scientific article published on January 2006

Functional abstraction as a method to discover knowledge in gene ontologies

scientific article (publication date: 2014)

Functional genomics of pain in analgesic drug development and therapy

scientific article published on 06 April 2013

Functional genomics suggest neurogenesis in the adult human olfactory bulb

scientific article published on 09 August 2013

Functional variants of the human 5-lipoxygenase gene and their genetic diagnosis

scientific article

GCH1 haplotype determines vascular and plasma biopterin availability in coronary artery disease effects on vascular superoxide production and endothelial function

scientific article published on July 2008

GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

scientific journal article

Genetic diagnostics of functional variants of the human dopamine D2 receptor gene.

scientific article

Genetic modulation of the pharmacological treatment of pain

scientific article published on 15 July 2009

Genetic mutations that prevent pain: implications for future pain medication

scientific article published on February 2008

Genetic predictors of the clinical response to opioid analgesics: clinical utility and future perspectives

scientific article

Genetic variability of pain perception and treatment—clinical pharmacological implications ⬇️

scientific article published on February 23, 2011

Genetic variants altering dopamine D2 receptor expression or function modulate the risk of opiate addiction and the dosage requirements of methadone substitution

scientific article published in June 2009

Genetic-epigenetic interaction modulates μ-opioid receptor regulation

scientific article

Genetically polymorphic OCT1: another piece in the puzzle of the variable pharmacokinetics and pharmacodynamics of the opioidergic drug tramadol

scientific article

Genetics of Opioid Actions

article

High pain sensitivity is distinct from high susceptibility to non-painful sensory input at threshold level

scientific article published on 01 February 2011

High-Throughput Analysis of Global DNA Methylation Using Methyl-Sensitive Digestion

scientific article

Higher pain scores, similar opioid doses and side effects associated with antipyretic analgesics in specialised tertiary pain care

scientific article published on 20 May 2010

Highly sensitive determination of HCV protease inhibitors boceprevir (SCH 503034) and telaprevir (VX 950) in human plasma by LC-MS/MS.

scientific article published on 14 October 2009

How Many and Which Odor Identification Items Are Needed to Establish Normal Olfactory Function?

scientific article published on 8 February 2016

Human models of pain for the prediction of clinical analgesia

Human pharmacological approaches to TRP-ion-channel-based analgesic drug development

article

Identification of Molecular Fingerprints in Human Heat Pain Thresholds by Use of an Interactive Mixture Model R Toolbox (AdaptGauss)

scientific article

Identification of disease-distinct complex biomarker patterns by means of unsupervised machine-learning using an interactive R toolbox (Umatrix)

scholarly article by Jörn Lötsch et al published 20 April 2018 in Big Data Analytics

Impact of donor and recipient IL28B rs12979860 genotypes on hepatitis C virus liver graft reinfection

scientific article published on 13 December 2010

Impact of ribavirin on HCV replicon RNA decline during treatment with interferon-α and the protease inhibitors boceprevir or telaprevir

scientific article

Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients

scientific article published on 22 September 2010

Increased CNS uptake and enhanced antinociception of morphine-6-glucuronide in rats after inhibition of P-glycoprotein

scientific article published in October 2002

Influence of (S)-ketamine on human motor cortex excitability

scientific article

Inhibition of GTP cyclohydrolase attenuates tumor growth by reducing angiogenesis and M2-like polarization of tumor associated macrophages.

scientific article

Inhibition of GTP cyclohydrolase reduces cancer pain in mice and enhances analgesic effects of morphine

scientific article published on 17 June 2012

Insidious intoxication after morphine treatment in renal failure: delayed onset of morphine-6-glucuronide action

scientific article

Integrated Computational Analysis of Genes Associated with Human Hereditary Insensitivity to Pain. A Drug Repurposing Perspective

scientific article published on 08 August 2017

Intranasal volume and olfactory function

scientific article published in November 2002

Inverted Perceptual Judgment of Nociceptive Stimuli at Threshold Level following Inconsistent Cues

scientific article

Is morphine-3-glucuronide of therapeutic relevance?

scientific article

Kinetics of serum brain-derived neurotrophic factor following low-intensity versus high-intensity exercise in men and women

scientific article published in October 2012

Lack of Analgesic Activity of Morphine-6-glucuronide after Short-term Intravenous Administration in Healthy Volunteers

scientific article published on 01 December 1997

Lack of fluconazole effects on human chemosensation

scientific article published on 01 January 2015

Letter to the Editor: Pyrosequencing™-based screening for the genetic polymorphism CYP2B6 1459 C>T

scientific article published on 01 October 2009

Linkage between increased nociception and olfaction via a SCN9A haplotype

scientific article

Loss of Olfactory Function Leads to a Decrease of Trigeminal Sensitivity

scientific article published on 01 February 1996

Low-dose drug combinations along molecular pathways could maximize therapeutic effectiveness while minimizing collateral adverse effects

scientific article published on 13 October 2011

Machine Learning and Pathway Analysis-Based Discovery of Metabolomic Markers Relating to Chronic Pain Phenotypes

scientific article published in 2022

Machine Learning in Human Olfactory Research.

scientific article published in January 2019

Machine learning in pain research.

scientific article published on 24 November 2017

Machine-Learned Association of Next-Generation Sequencing-Derived Variants in Thermosensitive Ion Channels Genes with Human Thermal Pain Sensitivity Phenotypes

scientific article published on 19 June 2020

Machine-Learned Data Structures of Lipid Marker Serum Concentrations in Multiple Sclerosis Patients Differ from Those in Healthy Subjects

scientific article

Machine-learned analysis of global and glial/opioid intersection-related DNA methylation in patients with persistent pain after breast cancer surgery

scientific article published on 27 November 2019

Machine-learned analysis of quantitative sensory testing responses to noxious cold stimulation in healthy subjects

scientific article published on 16 January 2018

Machine-learned analysis of the association of next-generation sequencing based human TRPV1 and TRPA1 genotypes with the sensitivity to heat stimuli and topically applied capsaicin

scientific article published on 27 March 2018

Machine-learned analysis of the association of next-generation sequencing-based genotypes with persistent pain after breast cancer surgery

scientific article published on 01 October 2019

Machine-learned cluster identification in high-dimensional data

scientific article

Machine-learned identification of psychological subgroups with relation to pain interference in patients after breast cancer treatments

scientific article published on 07 February 2020

Machine-learned pattern identification in olfactory subtest results

scientific article published on 20 October 2016

Machine-learned selection of psychological questionnaire items relevant to the development of persistent pain after breast cancer surgery

article

Machine-learning based lipid mediator serum concentration patterns allow identification of multiple sclerosis patients with high accuracy

scientific article published in Scientific Reports

Machine-learning-derived classifier predicts absence of persistent pain after breast cancer surgery with high accuracy

scholarly article by Jörn Lötsch et al published 6 June 2018 in Breast Cancer Research and Treatment

Machine-learning-derived rules set excludes risk of Parkinson's disease in patients with olfactory or gustatory symptoms with high accuracy

scientific article published on 01 November 2019

Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment

scientific article published on 14 August 2009

Methadone induces hypermethylation of human DNA.

scientific article published on 4 September 2015

MicroRNAs as new players in the pain game

scientific article published on 24 February 2011

Misestimating the role of an active metabolite when modeling the effects after administration of the parent compound only

scientific article published on 01 July 2006

Modulation of the central nervous effects of levomethadone by genetic polymorphisms potentially affecting its metabolism, distribution, and drug action

scientific article

Morphine and Its Metabolites After Patient-Controlled Analgesia

Morphine and its metabolites after patient-controlled analgesia: considerations for respiratory depression

scientific article published in March 2011

Morphine is not a prodrug

scientific article published on 01 June 2015

Morphine metabolites as novel analgesic drugs?

scientific article published on October 2004

Morphine metabolites: Clinical implications

Morphine-6-glucuronide: an analgesic of the future?

scientific article

Multimodal distribution of human cold pain thresholds

scientific article published on 20 May 2015

NSAIDs, Pharmacokinetics

NSAIDs, Pharmacokinetics

Necessity and risks of arterial blood sampling in healthy volunteer studies

scientific article published in October 2012

Next-generation sequencing of human opioid receptor genes based on a custom AmpliSeq™ library and ion torrent personal genome machine

scientific article

Next-generation sequencing of the human TRPV1 gene and the regulating co-players LTB4R and LTB4R2 based on a custom AmpliSeq™ panel

scientific article

Nimodipine plasma concentration and retinal blood flow in healthy subjects

scientific article

No contribution of morphine-6-glucuronide to clinical morphine effects after short-term administration

scientific article published in November 1998

Non-invasive combined surrogates of remifentanil blood concentrations with relevance to analgesia

scientific article

Olfactory and trigeminal event-related potentials in migraine

article by K Grosser et al published September 2000 in Cephalalgia

Olfactory and trigeminal event-related potentials in migraine

scientific article published on 01 September 2000

Olfactory drug effects approached from human-derived data

scientific article

Olfactory function in mild cognitive impairment and Alzheimer's disease: an investigation using psychophysical and electrophysiological techniques

scientific article

Opioid metabolites

scientific article

Opioid‐mediated drug actions cannot be concluded from naloxone induced reversal of anti‐nociceptive effects in behavioural tests only ⬇️

scientific article published on November 1, 2010

Optimal distribution-preserving downsampling of large biomedical data sets (opdisDownsampling)

scientific article published on 05 August 2021

Pain in the network of genetic and epigenetic control.

scientific article

Pain in the trigeminal system: irritation of the nasal mucosa using short- and long-lasting stimuli

scientific article

Pain research funding by the European Union Seventh Framework Programme

scientific article published on 01 May 2015

Pathophysiological mechanisms of neuropathic pain: comparison of sensory phenotypes in patients and human surrogate pain models

scientific article published on 24 February 2018

Pattern of neuropathic pain induced by topical capsaicin application in healthy subjects

scientific article published in March 2015

Peripheral opioid analgesia in experimental human pain models

scientific article

Pharmacoepigenetics of the role of DNA methylation in μ-opioid receptor expression in different human brain regions

scientific article

Pharmacogenetics of Pain Medication

Pharmacogenetics of new analgesics

scientific article

Pharmacokinetic Modeling of M6G Formation after Oral Administration of Morphine in Healthy Volunteers

scientific article published on 01 April 1999

Pharmacokinetic modeling to predict morphine and morphine-6-glucuronide plasma concentrations in healthy young volunteers

scientific article published in August 2002

Pharmacokinetic-pharmacodynamic modeling of opioids

scientific article

Pharmacokinetic-pharmacodynamic modeling of the miotic effects of dihydrocodeine in humans

scientific article published on 5 September 2007

Pharmacokinetic-pharmacodynamic relationship of levodopa with and without tolcapone in patients with Parkinson's disease

scientific article

Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.

scientific article

Pharmacokinetics of morphine and its glucuronides after intravenous infusion of morphine and morphine-6-glucuronide in healthy volunteers*

scientific article published on 01 September 1996

Pharmacokinetics of morphine are not altered in subjects with Gilbert's syndrome

scientific article published in August 2003

Pharmacokinetics of morphine-6-glucuronide and its formation from morphine after intravenous administration

scientific article

Pharmacokinetics of non-intravenous formulations of fentanyl

scientific article published on January 2013

Pleiotropic effects of morphine-6beta-glucuronide.

scientific article published in June 2009

Population pharmacokinetics of fast release oral diclofenac in healthy volunteers: relation to pharmacodynamics in an experimental pain model.

scientific article published on January 2000

Potential biomarkers for persistent and neuropathic pain therapy

scientific article published on 10 February 2019

Prediction of persistent post-surgery pain by preoperative cold pain sensitivity: biomarker development with machine-learning-derived analysis.

scientific article published in October 2017

Predictive factors for response to a boosted dual HIV-protease inhibitor therapy with saquinavir and lopinavir in extensively pre-treated patients.

scientific article published on January 2007

Principle components analysis of pain thresholds to thermal, electrical, and mechanical stimuli suggests a predominant common source of variance

scientific article

Probenecid interacts with the pharmacokinetics of morphine-6-glucuronide in humans

scientific article published in December 2004

Process Pharmacology: A Pharmacological Data Science Approach to Drug Development and Therapy

scientific article

Prognostic factors of olfactory dysfunction

scientific article published in April 2010

Programming of a flexible computer simulation to visualize pharmacokinetic-pharmacodynamic models.

scientific article published in January 2004

Pyrosequencing-based screening for genetic polymorphisms in cytochrome P450 2B6 of potential clinical relevance

scientific article published on October 2006

Pyrosequencing™ of polymorphisms in the COX-2 gene (PTGS2) with reported clinical relevance

article

Quantitation of ribavirin in human plasma and red blood cells using LC-MS/MS.

scientific article published on 29 January 2014

Quantitative sensory testing response patterns to capsaicin- and ultraviolet-B-induced local skin hypersensitization in healthy subjects: a machine-learned analysis

scientific article published on 08 July 2017

Quick discrimination of A(delta) and C fiber mediated pain based on three verbal descriptors

scientific article

R-flurbiprofen attenuates experimental autoimmune encephalomyelitis in mice

scientific article

Rapid genotyping for relevant CYP1A2 alleles by pyrosequencing

scientific article

Rapid identification of three functionally relevant polymorphisms in the OATP1B1 transporter gene using Pyrosequencing

scientific article published in March 2006

Rapid screening for potentially relevant polymorphisms in the human fatty acid amide hydrolase gene using Pyrosequencing

scientific article published on 22 June 2007

Reduced hyperalgesia in homozygous carriers of a GTP cyclohydrolase 1 haplotype

scientific article published on 18 April 2008

Regulation of circulating endocannabinoids associated with cancer and metastases in mice and humans

scientific article

Relative bioavailability and pharmacodynamic effects of methantheline compared with atropine in healthy subjects

scientific article published on 21 April 2012

Relevance of frequent mu-opioid receptor polymorphisms for opioid activity in healthy volunteers

scientific article published in May 2006

Reliable Screening for a Pain-Protective Haplotype in the GTP Cyclohydrolase 1 Gene (GCH1) Through the Use of 3 or Fewer Single Nucleotide Polymorphisms

article

Reply to "Can topical capsaicin induce a neuropathic pain?".

scientific article published in July 2015

Respiratory and miotic effects of morphine in healthy volunteers when P-glycoprotein is blocked by quinidine

scientific article published in October 2003

Role of nitric oxide in zymosan induced paw inflammation and thermal hyperalgesia

scientific article published in February 2001

Role of nucleoside transporters SLC28A2/3 and SLC29A1/2 genetics in ribavirin therapy: protection against anemia in patients with chronic hepatitis C.

scientific article published in May 2011

Screening for IL28B gene variants identifies predictors of hepatitis C therapy success

scientific article published in January 2010

Selective antagonism of opioid-induced ventilatory depression by an ampakine molecule in humans without loss of opioid analgesia

scientific article

Self-ratings of higher olfactory acuity contrast with reduced olfactory test results of fibromyalgia patients

scientific article published on 15 September 2012

Separating brain processing of pain from that of stimulus intensity

scientific article published on 16 June 2011

Similar Maximum Systemic but not Local Cyclooxygenase-2 Inhibition by 50 mg Lumiracoxib and 90 mg Etoricoxib: A Randomized Controlled Trial in Healthy Subjects

scientific article published on 28 January 2014

Simultaneous and sensitive LC–MS/MS determination of tetrahydrocannabinol and metabolites in human plasma

scientific article published on 28 October 2012

Simultaneous fitting of R- and S-ibuprofen plasma concentrations after oral administration of the racemate

scientific article

Simultaneous fitting of R- and S-ibuprofen plasma concentrations after oral administration of the racemate

Simultaneous screening for three mutations in the ABCB1 gene

article

Sind μ-Opioidrezeptorpolymorphismen wichtig für die Opioidtherapie?

scientific article published on 01 October 2005

Single and combined IL28B, ITPA and SLC28A3 host genetic markers modulating response to anti-hepatitis C therapy

scientific article published in December 2011

Single-step identification of all length polymorphisms in the UGT1A1 gene promoter.

scientific article published in March 2004

Smell of pain: intersection of nociception and olfaction

scientific article published on 5 May 2016

Sniffing out pharmacology: interactions of drugs with human olfaction

scientific article published on 21 February 2012

Synaesthesia or vivid imagery? A single case fMRI study of visually induced olfactory perception

scientific article published in January 2014

THC may reproducibly induce electrical hyperalgesia in healthy volunteers

scientific article published on 28 July 2014

TRPA1 Sensitization Produces Hyperalgesia to Heat but not to Cold Stimuli in Human Volunteers

scientific article published on 01 April 2019

The 5-hydroxytryptamine 4 receptor agonist mosapride does not antagonize morphine-induced respiratory depression

scientific article

The Consequence of Concomitantly Present Functional Genetic Variants for the Identification of Functional Genotype–Phenotype Associations in Pain

scientific article published on 11 June 2008

The Partial 5-Hydroxytryptamine1A Receptor Agonist Buspirone does not Antagonize Morphine-induced Respiratory Depression in Humans

scientific article published on 01 January 2007

The clinical significance of electrophysiological measures of olfactory function

scientific article published on 24 March 2006

The cyclooxygenase 2 genetic variant -765G>C does not modulate the effects of celecoxib on prostaglandin E2 production.

scientific article

The human mu-opioid receptor gene polymorphism 118A > G decreases cortical activation in response to specific nociceptive stimulation

scientific article published in December 2006

The human operculo-insular cortex is pain-preferentially but not pain-exclusively activated by trigeminal and olfactory stimuli

scientific article

The influence of inhibition of probenecid sensitive transporters on the central nervous system (CNS) uptake and the antinociceptive activity of morphine-6-glucuronide in rats

scientific article published in August 2002

The influence of stimulus duration on the reliability of pain ratings after nociceptive stimulation of the nasal mucosa with CO2

scientific article published on 01 January 1997

The mu-opioid agonist remifentanil attenuates hyperalgesia evoked by blunt and punctuated stimuli with different potency: a pharmacological evaluation of the freeze lesion in humans

scientific article

The mu-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers

scientific article published in September 2006

The negative mucosal potential: separating central and peripheral effects of NSAIDs in man.

scientific article published on January 1997

The pharmacogenetic background of hepatitis C treatment

scientific article published on 03 March 2012

The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine

scientific article published in January 2002

The transfer half-life of morphine-6-glucuronide from plasma to effect site assessed by pupil size measurement in healthy volunteers

scientific article published in December 2001

Tissue distribution of imipenem in critically ill patients

scientific article

Trigeminal chemosensitivity: Differences in relation to the time of the day.

scientific article published in December 1998

Use of Computational Functional Genomics in Drug Discovery and Repurposing for Analgesic Indications

scientific article published on 19 January 2018

Using a Standardized Clinical Quantitative Sensory Testing Battery to Judge the Clinical Relevance of Sensory Differences Between Adjacent Body Areas

scientific article published on 13 June 2016

Verapamil decreases glucuronidase activity in the gut.

scientific article

Visual evoked potentials in migraine patients: alterations depend on pattern spatial frequency

scientific article published in June 1999

Visually guided preprocessing of bioanalytical laboratory data using an interactive R notebook (pguIMP)

scientific article published on 01 October 2021

Wem gefällt Placebo?

scientific article published on 01 May 2008

What do all the (human) micro-RNAs do?

scientific article published on 18 November 2014

Ziconotide for treatment of severe chronic pain

scientific article published on 21 April 2010

[Computer-assisted teaching in pharmacology]

scientific article published on 01 January 1993

[Therapy with opioids in liver or renal failure]

scientific article published on 01 June 1999

µ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain

scientific article

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