List of works - Eugenio Vilanova

A simple and rapid HPLC-MS method for the simultaneous determination of epinephrine, norepinephrine, dopamine and 5-hydroxytryptamine: application to the secretion of bovine chromaffin cell cultures

scientific article

A stereospecific phosphotriesterase in hen liver and brain

scientific article published in January 1998

Acetylcholine-hydrolyzing activities in soluble brain fraction: Characterization with reversible and irreversible inhibitors

scientific article

An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of neuropathy target esterase (NTE).

scientific article

An automatable microassay for phenyl valerate esterase activities sensitive to organophosphorus compounds

scientific article published on 01 December 1996

An in vitro approach for demonstrating the critical role of serum albumin in the detoxication of the carbamate carbaryl at in vivo toxicologically relevant concentrations.

scientific article published on 31 August 2006

An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods.

scientific article published on 03 February 2014

Anomalous biochemical responses in tests of the delayed neuropathic potential of methamidophos (O,S-dimethyl phosphorothioamidate), its resolved isomers and of some higher O-alkyl homologues

scientific article

Biochemical and clinical tests of the delayed neuropathic potential of some O-alkyl O-dichlorophenyl phosphoramidate analogues of methamidophos (O,S-dimethyl phosphorothioamidate).

scientific article published in January 1989

Biochemical properties and possible toxicological significance of various forms of NTE.

scientific article

Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity

scientific article

Bovine chromaffin cells as in vitro model for the study of non-cholinergic toxic effects of organophosphorus compounds.

scientific article published in January 1997

Bovine chromaffin cells in culture show carboxylesterase activities sensitive to organophosphorus compounds

scientific article published in September 1996

Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain.

scientific article

Characterization and Evolution of Exposure to Volatile Organic Compounds in the Spanish Shoemaking Industry over a 5-Year Period

article

Chicken Serum Albumin Hydrolyzes Dichlorophenyl Phosphoramidates by a Mechanism Based on Transient Phosphorylation

scientific article published on 01 December 1998

Cholinesterase assay by an efficient fixed time endpoint method

scientific article published on 4 November 2014

Chromatographic discrimination of soluble neuropathy target esterase isoenzymes and related phenyl valerate esterases from chicken brain, spinal cord, and sciatic nerve.

scientific article published in May 1997

Comparative hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate and paraoxon in different tissues of vertebrates

scientific article published on 30 March 2007

Comparison of chromaffin cells from several animal sources for their use as an in vitro model to study the mechanism of organophosphorous toxicity

scientific article published on 28 April 2006

Copper activation of organophosporus compounds detoxication by chicken serum.

scientific article

Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts.

scientific article

Detection of clinical interactions between methadone and anti-retroviral compounds using an enantioselective capillary electrophoresis for methadone analysis

scientific article

Dichlorophenyl phosphoramidates as substrates for avian and mammalian liver phosphotriesterases: activity levels, calcium dependence and stereospecificity

scientific article published on 01 May 1999

Discrimination of carboxylesterases of chicken neural tissue by inhibition with a neuropathic, non-neuropathic organophosphorus compounds and neuropathy promoter.

scientific article published in October 1997

Distinct structures of the α-fucose branches in fucosylated chondroitin sulfates do not affect their anticoagulant activity.

scientific article published on 19 June 2015

Distribution and some biochemical properties of rat paraoxonase activity

scientific article published on 01 November 1990

Distribution of serum paraoxon hydrolyzing activity in a large Spanish population using a routine automized method in clinical laboratory

scientific article published in July 2003

EDTA-resistant and sensitive phosphotriesterase activities associated with albumin and lipoproteins in rabbit serum.

scientific article published in January 1999

Effect of some metallic cations and organic compounds on theO-hexylO-2,5-dichlorophenyl phosphoramidate hydrolysing activity in hen plasma

article

Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells.

scientific article published on 23 April 2016

Enzyme concentration as an important factor in the in vitro testing of the stereospecificity of the enzymatic hydrolysis of organophosphorus compounds

article

Enzymes involved in the detoxification of organophosphorus, carbamate and pyrethroid insecticides through hydrolysis.

scientific article

Esterases hydrolyze phenyl valerate activity as targets of organophosphorus compounds

scientific article published on 14 April 2016

Expression of Neuropathy Target Esterase in mouse embryonic stem cells during differentiation.

scientific article

Expression of biomarker genes of differentiation in D3 mouse embryonic stem cells after exposure to different embryotoxicant and non-embryotoxicant model chemicals

scientific article published on 30 September 2015

Functional pathways altered after silencing Pnpla6 (the codifying gene of neuropathy target esterase) in mouse embryonic stem cells under differentiation.

scientific article published on 19 October 2013

Future applications of phosphotriesterases in the prophylaxis and treatment of organophosporus insecticide and nerve agent poisonings.

scientific article published on June 2004

Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox

scientific article published on 09 January 2014

Hen liver and plasma can metabolize hexyl-DCP phosphoramidate at a rate comparable to that of rat.

scientific article

Hydrolysis of carbaryl by human serum albumin

scientific article published on 2 July 2004

In vivo inhibition by mipafox of soluble and particulate forms of organophosphorus neuropathy target esterase (NTE) in hen sciatic nerve.

scientific article

Inhibition and aging of neuropathy target esterase by the stereoisomers of a phosphoramidate related to methamidophos.

scientific article published on December 1997

Inhibition with spontaneous reactivation and the "ongoing inhibition" effect of esterases by biotinylated organophosphorus compounds: S9B as a model

scientific article published on 20 May 2010

Inhibition with spontaneous reactivation of carboxyl esterases by organophosphorus compounds: paraoxon as a model

scientific article published on 14 December 2010

Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate- and acetylcholine-hydrolyzing activities in chicken brain

article

Interactions of neuropathy inducers and potentiators/promoters with soluble esterases

scientific article published on 28 November 2012

Kinetic interactions of a neuropathy potentiator (phenylmethylsulfonyl fluoride) with the neuropathy target esterase and other membrane bound esterases

scientific article published on 27 September 2013

Kinetics of inhibition of soluble peripheral nerve esterases by PMSF: a non-stable compound that potentiates the organophosphorus-induced delayed neurotoxicity

scientific article published on 22 February 2012

Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system.

scientific article published on 12 May 2011

Local application of neuropathic organophosphorus compounds to hen sciatic nerve: inhibition of neuropathy target esterase and peripheral neurological impairments

scientific article published in December 1992

Long-term decline of the Amazon carbon sink ⬇️

scientific article published on March 2015

Low non-neuropathic tri-o-cresyl phosphate (TOCP) doses inhibit neuropathy target esterase near the neuropathic threshold in n-hexane pretreated hens

scientific article published in April 1988

Model equations for the kinetics of covalent irreversible enzyme inhibition and spontaneous reactivation: esterases and organophosphorus compounds.

scientific article published on January 2009

NTE and non-NTE esterases in brain membrane: kinetic characterization with organophosphates

scientific article published on 6 April 2012

New insights on molecular interactions of organophosphorus pesticides with esterases.

scientific article

Non-calcium dependent activity hydrolysing organophosphorus compounds in hen plasma

scientific article published on 01 February 1994

Organophosphorus inhibition and heat inactivation kinetics of particulate and soluble forms of peripheral nerve neuropathy target esterase.

scientific article published in August 1995

Organophosphorus pesticide chlorpyrifos and its metabolites alter the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells in a comparable way to other model neurodevelopmental toxicants

scientific article published on 29 August 2014

Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer.

scientific article published on 16 November 2006

Partial characterization of neuropathy target esterase and related phenyl valerate esterases from bovine adrenal medulla

scientific article

Peripheral nerve soluble esterases are spontaneously reactivated after inhibition by paraoxon: implications for a new definition of neuropathy target esterase.

scientific article published in May 1999

Phenyl valerate esterase activity of human butyrylcholinesterase

scientific article

Phenylmethylsulfonyl fluoride, a potentiator of neuropathy, alters the interaction of organophosphorus compounds with soluble brain esterases

scientific article published on 10 October 2012

Phosphotriesterase activity identified in purified serum albumins

scientific article published on 01 March 1998

Phthalates and organophosphorus compounds as cholinesterase inhibitors in fractions of industrial hexane impurities

scholarly article by J L Vicedo et al published April 1985 in Archives of Toxicology

Plasma phenylacetate and 1-naphthyl acetate hydrolyzing activities of wild birds as possible non-invasive biomarkers of exposure to organophosphorus and carbamate insecticides

scientific article published on 16 November 2006

Properties of partly preinhibited hen brain neuropathy target esterase

scientific article published in June 1993

Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition

scientific article published in April 2003

Purification and characterization of naturally soluble neuropathy target esterase from chicken sciatic nerve by HPLC and western blot.

scientific article

RNA transcripts for the quantification of differentiation allow marked improvements in the performance of embryonic stem cell test (EST).

scientific article published on 10 August 2015

Rabbit serum albumin hydrolyzes the carbamate carbaryl.

scientific article

Recovery of neuropathy target esterase activity after inhibition with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures

article

Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches

scientific article published on 6 March 2015

Reversible inhibition can profoundly mislead studies on progressive inhibition of enzymes: the interaction of paraoxon with soluble neuropathy target esterase.

scientific article

Roles of NTE protein and encoding gene in development and neurodevelopmental toxicity

scientific article

Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration

scientific article published in April 1988

Sensitivity to tri-o-cresylphosphate neurotoxicity on n-hexane exposed hens as a model of simultaneous hexacarbon solvent and organophosphorus occupational intoxication.

scientific article published in February 1987

Separating esterase targets of organophosphorus compounds in the brain by preparative chromatography

scientific article published on 17 December 2013

Separation of two forms of neuropathy target esterase in the soluble fraction of the hen sciatic nerve.

scientific article published in August 1995

Serum albumin is as efficient as paraxonase in the detoxication of paraoxon at toxicologically relevant concentrations.

scientific article published on 3 July 2008

Serum albumins and detoxication of anti-cholinesterase agents.

scientific article published on 6 March 2010

Serum cholinesterase inhibitors in the commercial hexane impurities.

scientific article

Silencing of PNPLA6, the neuropathy target esterase (NTE) codifying gene, alters neurodifferentiation of human embryonal carcinoma stem cells (NT2).

scientific article

Soluble and particulate forms of the organophosphorus neuropathy target esterase in hen sciatic nerve

scientific article

Soluble and particulate organophosphorus neuropathy target esterase in brain and sciatic nerve of the hen, cat, rat, and chick.

scientific article published in December 1993

Stereospecific hydrolysis of a phosphoramidate as a model to understand the role of biotransformation in the neurotoxicity of chiral organophosphorus compounds.

scientific article

Stereospecific hydrolysis of a phosphoramidate used as an OPIDP model by human sera with PON1 192 alloforms.

scientific article

Sulfated polysaccharides from marine sponges (Porifera): an ancestor cell-cell adhesion event based on the carbohydrate-carbohydrate interaction.

scientific article published on 24 April 2009

The inhibition of the high sensitive peripheral nerve soluble esterases by mipafox. A new mathematical processing for the kinetics of inhibition of esterases by organophosphorus compounds

scientific article

The kinetics of O-hexyl O-2,5-dichlorophenyl phosphoramidate hydrolysing activity in hen plasma

scientific article published in June 1993

The role of nicotinic receptors and calcium channels in mipafox induced inhibition of catecholamine release in bovine chromaffin cells

scientific article published on 01 July 1996

The role of phosphotriesterases in the detoxication of organophosphorus compounds.

scientific article

Tyrosine hydroxylase activity of immobilized tyrosinase on enzacryl-AA and CPG-AA supports: Stabilization and properties

scientific article published on 01 November 1984

[Costs of a low payment maintenance treatment with methadone]

scientific article published on 01 February 2000

List of works by Eugenio Vilanova

A simple and rapid HPLC-MS method for the simultaneous determination of epinephrine, norepinephrine, dopamine and 5-hydroxytryptamine: application to the secretion of bovine chromaffin cell cultures

A stereospecific phosphotriesterase in hen liver and brain

Acetylcholine-hydrolyzing activities in soluble brain fraction: Characterization with reversible and irreversible inhibitors

An alternative in vitro method for detecting neuropathic compounds based on acetylcholinesterase inhibition and on inhibition and aging of neuropathy target esterase (NTE).

An automatable microassay for phenyl valerate esterase activities sensitive to organophosphorus compounds

An in vitro approach for demonstrating the critical role of serum albumin in the detoxication of the carbamate carbaryl at in vivo toxicologically relevant concentrations.

An integrated approach for detecting embryotoxicity and developmental toxicity of environmental contaminants using in vitro alternative methods.

Anomalous biochemical responses in tests of the delayed neuropathic potential of methamidophos (O,S-dimethyl phosphorothioamidate), its resolved isomers and of some higher O-alkyl homologues

Biochemical and clinical tests of the delayed neuropathic potential of some O-alkyl O-dichlorophenyl phosphoramidate analogues of methamidophos (O,S-dimethyl phosphorothioamidate).

Biochemical properties and possible toxicological significance of various forms of NTE.

Bovine chromaffin cell cultures as model to study organophosporus neurotoxicity

Bovine chromaffin cells as in vitro model for the study of non-cholinergic toxic effects of organophosphorus compounds.

Bovine chromaffin cells in culture show carboxylesterase activities sensitive to organophosphorus compounds

Butyrylcholinesterase identification in a phenylvalerate esterase-enriched fraction sensitive to low mipafox concentrations in chicken brain.

Characterization and Evolution of Exposure to Volatile Organic Compounds in the Spanish Shoemaking Industry over a 5-Year Period

Chicken Serum Albumin Hydrolyzes Dichlorophenyl Phosphoramidates by a Mechanism Based on Transient Phosphorylation

Cholinesterase assay by an efficient fixed time endpoint method

Chromatographic discrimination of soluble neuropathy target esterase isoenzymes and related phenyl valerate esterases from chicken brain, spinal cord, and sciatic nerve.

Comparative hydrolysis of O-hexyl O-2,5-dichlorophenyl phosphoramidate and paraoxon in different tissues of vertebrates

Comparison of chromaffin cells from several animal sources for their use as an in vitro model to study the mechanism of organophosphorous toxicity

Copper activation of organophosporus compounds detoxication by chicken serum.

Cytotoxic effect against 3T3 fibroblasts cells of saffron floral bio-residues extracts.

Detection of clinical interactions between methadone and anti-retroviral compounds using an enantioselective capillary electrophoresis for methadone analysis

Dichlorophenyl phosphoramidates as substrates for avian and mammalian liver phosphotriesterases: activity levels, calcium dependence and stereospecificity

Discrimination of carboxylesterases of chicken neural tissue by inhibition with a neuropathic, non-neuropathic organophosphorus compounds and neuropathy promoter.

Distinct structures of the α-fucose branches in fucosylated chondroitin sulfates do not affect their anticoagulant activity.

Distribution and some biochemical properties of rat paraoxonase activity

Distribution of serum paraoxon hydrolyzing activity in a large Spanish population using a routine automized method in clinical laboratory

EDTA-resistant and sensitive phosphotriesterase activities associated with albumin and lipoproteins in rabbit serum.

Effect of some metallic cations and organic compounds on theO-hexylO-2,5-dichlorophenyl phosphoramidate hydrolysing activity in hen plasma

Effects of mipafox, paraoxon, chlorpyrifos and its metabolite chlorpyrifos-oxon on the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells.

Enzyme concentration as an important factor in the in vitro testing of the stereospecificity of the enzymatic hydrolysis of organophosphorus compounds

Enzymes involved in the detoxification of organophosphorus, carbamate and pyrethroid insecticides through hydrolysis.

Esterases hydrolyze phenyl valerate activity as targets of organophosphorus compounds

Expression of Neuropathy Target Esterase in mouse embryonic stem cells during differentiation.

Expression of biomarker genes of differentiation in D3 mouse embryonic stem cells after exposure to different embryotoxicant and non-embryotoxicant model chemicals

Functional pathways altered after silencing Pnpla6 (the codifying gene of neuropathy target esterase) in mouse embryonic stem cells under differentiation.

Future applications of phosphotriesterases in the prophylaxis and treatment of organophosporus insecticide and nerve agent poisonings.

Genomic and phenotypic alterations of the neuronal-like cells derived from human embryonal carcinoma stem cells (NT2) caused by exposure to organophosphorus compounds paraoxon and mipafox

Hen liver and plasma can metabolize hexyl-DCP phosphoramidate at a rate comparable to that of rat.

Hydrolysis of carbaryl by human serum albumin

In vivo inhibition by mipafox of soluble and particulate forms of organophosphorus neuropathy target esterase (NTE) in hen sciatic nerve.

Inhibition and aging of neuropathy target esterase by the stereoisomers of a phosphoramidate related to methamidophos.

Inhibition with spontaneous reactivation and the "ongoing inhibition" effect of esterases by biotinylated organophosphorus compounds: S9B as a model

Inhibition with spontaneous reactivation of carboxyl esterases by organophosphorus compounds: paraoxon as a model

Interaction between substrates suggests a relationship between organophosphorus-sensitive phenylvalerate- and acetylcholine-hydrolyzing activities in chicken brain

Interactions of neuropathy inducers and potentiators/promoters with soluble esterases

Kinetic interactions of a neuropathy potentiator (phenylmethylsulfonyl fluoride) with the neuropathy target esterase and other membrane bound esterases

Kinetics of inhibition of soluble peripheral nerve esterases by PMSF: a non-stable compound that potentiates the organophosphorus-induced delayed neurotoxicity

Kinetics of the inhibitory interaction of organophosphorus neuropathy inducers and non-inducers in soluble esterases in the avian nervous system.

Local application of neuropathic organophosphorus compounds to hen sciatic nerve: inhibition of neuropathy target esterase and peripheral neurological impairments

Long-term decline of the Amazon carbon sink ⬇️

Low non-neuropathic tri-o-cresyl phosphate (TOCP) doses inhibit neuropathy target esterase near the neuropathic threshold in n-hexane pretreated hens

Model equations for the kinetics of covalent irreversible enzyme inhibition and spontaneous reactivation: esterases and organophosphorus compounds.

NTE and non-NTE esterases in brain membrane: kinetic characterization with organophosphates

New insights on molecular interactions of organophosphorus pesticides with esterases.

Non-calcium dependent activity hydrolysing organophosphorus compounds in hen plasma

Organophosphorus inhibition and heat inactivation kinetics of particulate and soluble forms of peripheral nerve neuropathy target esterase.

Organophosphorus pesticide chlorpyrifos and its metabolites alter the expression of biomarker genes of differentiation in D3 mouse embryonic stem cells in a comparable way to other model neurodevelopmental toxicants

Over-expression of neuropathy target esterase activity in bovine chromaffin cell cultures by adenovirus-mediated gene transfer.

Partial characterization of neuropathy target esterase and related phenyl valerate esterases from bovine adrenal medulla

Peripheral nerve soluble esterases are spontaneously reactivated after inhibition by paraoxon: implications for a new definition of neuropathy target esterase.

Phenyl valerate esterase activity of human butyrylcholinesterase

Phenylmethylsulfonyl fluoride, a potentiator of neuropathy, alters the interaction of organophosphorus compounds with soluble brain esterases

Phosphotriesterase activity identified in purified serum albumins

Phthalates and organophosphorus compounds as cholinesterase inhibitors in fractions of industrial hexane impurities

Plasma phenylacetate and 1-naphthyl acetate hydrolyzing activities of wild birds as possible non-invasive biomarkers of exposure to organophosphorus and carbamate insecticides

Properties of partly preinhibited hen brain neuropathy target esterase

Properties of phenyl valerate esterase activities from chicken serum are comparable with soluble esterases of peripheral nerves in relation with organophosphorus compounds inhibition

Purification and characterization of naturally soluble neuropathy target esterase from chicken sciatic nerve by HPLC and western blot.

RNA transcripts for the quantification of differentiation allow marked improvements in the performance of embryonic stem cell test (EST).

Rabbit serum albumin hydrolyzes the carbamate carbaryl.

Recovery of neuropathy target esterase activity after inhibition with mipafox and O-hexyl O-2,5-dichlorophenyl phosphoramidate in bovine chromaffin cell cultures

Resolving pathways of interaction of mipafox and a sarin analog with human acetylcholinesterase by kinetics, mass spectrometry and molecular modeling approaches

Reversible inhibition can profoundly mislead studies on progressive inhibition of enzymes: the interaction of paraoxon with soluble neuropathy target esterase.

Roles of NTE protein and encoding gene in development and neurodevelopmental toxicity

Sciatic nerve neuropathy target esterase. Methods of assay, proximo-distal distribution and regeneration

Sensitivity to tri-o-cresylphosphate neurotoxicity on n-hexane exposed hens as a model of simultaneous hexacarbon solvent and organophosphorus occupational intoxication.

Separating esterase targets of organophosphorus compounds in the brain by preparative chromatography