List of works - Michele M. Mazzanti

14-3-3ε marks the amyloid-stimulated microglia long-term activation

scientific article

ATP-dependent ionic permeability on nuclear envelope in in situ nuclei of Xenopus oocytes.

scientific article published on February 1994

ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress

scientific article

Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation ⬇️

scientific article published on 5 October 2018

Biochemical and electrophysiological studies on the mechanism of action of PNU-151774E, a novel antiepileptic compound

scientific article published in March 1999

Blockade of chloride intracellular ion channel 1 stimulates Abeta phagocytosis.

scientific article

CLIC1 Protein Accumulates in Circulating Monocyte Membrane during Neurodegeneration

scientific article published on 21 February 2020

CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia.

scientific article

CLIC1 functional expression is required for cAMP-induced neurite elongation in post-natal mouse retinal ganglion cells

scientific article published on 12 August 2014

Ca channel gating during cardiac action potentials

scientific article

Ca modulates outward current throughI K1 channels

scientific article published on 01 June 1990

Calcium binding promotes prion protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure.

scientific article

Calcium protects differentiating neuroblastoma cells during 50 Hz electromagnetic radiation

scientific article

Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets

scientific article

Chloride channels in the nuclear membrane ⬇️

scientific article published on 01 July 1991

Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress

scientific article published on 10 April 2010

Comparison between low-level 50 Hz and 900 MHz electromagnetic stimulation on single channel ionic currents and on firing frequency in dorsal root ganglion isolated neurons

scientific article published on 05 April 2006

Comparison of vertebrate and invertebrate CLIC proteins: the crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC

scientific article

Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution

scientific article

Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.

scientific article

Cytoskeletal control of rectification and expression of four substates in cardiac inward rectifier K+ channels

scientific article published on 01 February 1996

Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds

scientific article published on 05 October 2015

ERK-dependent modulation of cerebellar synaptic plasticity after chronic Delta9-tetrahydrocannabinol exposure.

scientific article published in May 2006

Effect of firing rate on the calcium permeability in adult neurons during spontaneous action potentials.

scientific article published on October 1992

Electrical dimension of the nuclear envelope.

scientific article

Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells

scientific article published on 18 November 2019

Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells

scientific article (publication date: June 2000)

Functional role of CLIC1 ion channel in glioblastoma-derived stem/progenitor cells

scientific article published on 10 October 2013

Functional role of low-voltage-activated dihydropyridine-sensitive Ca channels during the action potential in adult rat sensory neurones

scientific article published on 01 April 1996

Gating mechanism of the nuclear pore complex channel in isolated neonatal and adult mouse liver nuclei.

scientific article published on August 1999

Gating of L-type Ca2+ channels in embryonic chick ventricle cells: dependence on voltage, current and channel density.

scientific article

Identification of a nucleo-cytoplasmic ionic pathway by osmotic shock in isolated mouse liver nuclei

scientific article published on 01 January 1993

Intracellular Ca modulates K-inward rectification in cardiac myocytes

scientific article published on 01 January 1989

Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity

scientific journal article

Ion Permeability of the Nuclear Envelope

scientific article published on 01 February 1998

Ion channels in murine nuclei during early development and in fully differentiated adult cells

scientific article published in April 1991

Ionic Permeability on Isolated Mouse Liver Nuclei: Influence of ATP and Ca 2+

scientific article published on 01 June 1997

K channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells.

scientific article published on December 1988

Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts

scientific article

Mechanical transients initiated by ramp stretch and release to Po in frog muscle fibers

article

Metamorphic response of the CLIC1 chloride intracellular ion channel protein upon membrane interaction

scientific article published in June 2010

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current

scientific article

Na channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells

scientific article

Na channels that remain open throughout the cardiac action potential plateau.

scientific article

Outward sodium current in beating heart cells

scientific article

Parkin regulates kainate receptors by interacting with the GluK2 subunit

scientific article

Point mutations in the transmembrane region of the clic1 ion channel selectively modify its biophysical properties

scientific article

Potassium channels and the repolarization of cardiac cells.

scientific article published on January 1990

Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1

scientific article (publication date: 19 July 2002)

Regulation of the Na-conducting Ca channel during the cardiac action potential.

scientific article

Reversible redox modifications in the microglial proteome challenged by beta amyloid.

scientific article

Specific recognition of biologically active amyloid-β oligomers by a new surface plasmon resonance-based immunoassay and an in vivo assay in Caenorhabditis elegans

scientific article published on 26 June 2012

Structure of the Janus protein human CLIC2

scientific article

The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers

scientific article published on 06 July 2016

The Small Molecule GAL-201 Efficiently Detoxifies Soluble Amyloid β Oligomers: New Approach towards Oral Disease-Modifying Treatment of Alzheimer’s Disease

scientific article published in 2022

The Timing of the Excitatory-to-Inhibitory GABA Switch Is Regulated by the Oxytocin Receptor via KCC2

scientific article

The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?

scientific article published on 19 January 2010

The female epilepsy protein PCDH19 is a new GABAAR binding partner that regulates GABAergic transmission as well as migration and morphological maturation of hippocampal neurons.

scientific article published on 17 January 2018

The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition

scientific article

The pathological prion protein forms ionic conductance in lipid bilayer

scientific article published on 6 June 2011

Toxic effects of expanded ataxin-1 involve mechanical instability of the nuclear membrane

article

USING ATOMIC FORCE MICROSCOPY TO INVESTIGATE PATCH-CLAMPED NUCLEAR MEMBRANE

scientific article published on 01 November 1997

List of works by Michele M. Mazzanti

14-3-3ε marks the amyloid-stimulated microglia long-term activation

ATP-dependent ionic permeability on nuclear envelope in in situ nuclei of Xenopus oocytes.

ATR mediates a checkpoint at the nuclear envelope in response to mechanical stress

Antiestrogen- and tamoxifen-induced effects on calcium-activated chloride currents in epithelial cells carrying the ∆F508-CFTR point mutation ⬇️

Biochemical and electrophysiological studies on the mechanism of action of PNU-151774E, a novel antiepileptic compound

Blockade of chloride intracellular ion channel 1 stimulates Abeta phagocytosis.

CLIC1 Protein Accumulates in Circulating Monocyte Membrane during Neurodegeneration

CLIC1 function is required for beta-amyloid-induced generation of reactive oxygen species by microglia.

CLIC1 functional expression is required for cAMP-induced neurite elongation in post-natal mouse retinal ganglion cells

Ca channel gating during cardiac action potentials

Ca modulates outward current throughI K1 channels

Calcium binding promotes prion protein fragment 90-231 conformational change toward a membrane destabilizing and cytotoxic structure.

Calcium protects differentiating neuroblastoma cells during 50 Hz electromagnetic radiation

Chloride channels in cancer: Focus on chloride intracellular channel 1 and 4 (CLIC1 AND CLIC4) proteins in tumor development and as novel therapeutic targets

Chloride channels in the nuclear membrane ⬇️

Chloride intracellular channel 1 (CLIC1): Sensor and effector during oxidative stress

Comparison between low-level 50 Hz and 900 MHz electromagnetic stimulation on single channel ionic currents and on firing frequency in dorsal root ganglion isolated neurons

Comparison of vertebrate and invertebrate CLIC proteins: the crystal structures of Caenorhabditis elegans EXC-4 and Drosophila melanogaster DmCLIC

Crystal structure of a soluble form of the intracellular chloride ion channel CLIC1 (NCC27) at 1.4-A resolution

Crystal structure of the soluble form of the redox-regulated chloride ion channel protein CLIC4.

Cytoskeletal control of rectification and expression of four substates in cardiac inward rectifier K+ channels

Drug-repositioning opportunities for cancer therapy: novel molecular targets for known compounds

ERK-dependent modulation of cerebellar synaptic plasticity after chronic Delta9-tetrahydrocannabinol exposure.

Effect of firing rate on the calcium permeability in adult neurons during spontaneous action potentials.

Electrical dimension of the nuclear envelope.

Emerging Role of Cellular Prion Protein in the Maintenance and Expansion of Glioma Stem Cells

Functional characterization of the NCC27 nuclear protein in stable transfected CHO-K1 cells

Functional role of CLIC1 ion channel in glioblastoma-derived stem/progenitor cells

Functional role of low-voltage-activated dihydropyridine-sensitive Ca channels during the action potential in adult rat sensory neurones

Gating mechanism of the nuclear pore complex channel in isolated neonatal and adult mouse liver nuclei.

Gating of L-type Ca2+ channels in embryonic chick ventricle cells: dependence on voltage, current and channel density.

Identification of a nucleo-cytoplasmic ionic pathway by osmotic shock in isolated mouse liver nuclei

Intracellular Ca modulates K-inward rectification in cardiac myocytes

Involvement of the intracellular ion channel CLIC1 in microglia-mediated beta-amyloid-induced neurotoxicity

Ion Permeability of the Nuclear Envelope

Ion channels in murine nuclei during early development and in fully differentiated adult cells

Ionic Permeability on Isolated Mouse Liver Nuclei: Influence of ATP and Ca 2+

K channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells.

Lamin B1 overexpression increases nuclear rigidity in autosomal dominant leukodystrophy fibroblasts

Mechanical transients initiated by ramp stretch and release to Po in frog muscle fibers

Metamorphic response of the CLIC1 chloride intracellular ion channel protein upon membrane interaction

Metformin repositioning as antitumoral agent: selective antiproliferative effects in human glioblastoma stem cells, via inhibition of CLIC1-mediated ion current

Na channel kinetics during the spontaneous heart beat in embryonic chick ventricle cells

Na channels that remain open throughout the cardiac action potential plateau.

Outward sodium current in beating heart cells

Parkin regulates kainate receptors by interacting with the GluK2 subunit

Point mutations in the transmembrane region of the clic1 ion channel selectively modify its biophysical properties

Potassium channels and the repolarization of cardiac cells.

Recombinant CLIC1 (NCC27) assembles in lipid bilayers via a pH-dependent two-state process to form chloride ion channels with identical characteristics to those observed in Chinese hamster ovary cells expressing CLIC1

Regulation of the Na-conducting Ca channel during the cardiac action potential.

Reversible redox modifications in the microglial proteome challenged by beta amyloid.

Specific recognition of biologically active amyloid-β oligomers by a new surface plasmon resonance-based immunoassay and an in vivo assay in Caenorhabditis elegans

Structure of the Janus protein human CLIC2

The Anti-Prion Antibody 15B3 Detects Toxic Amyloid-β Oligomers

The Small Molecule GAL-201 Efficiently Detoxifies Soluble Amyloid β Oligomers: New Approach towards Oral Disease-Modifying Treatment of Alzheimer’s Disease

The Timing of the Excitatory-to-Inhibitory GABA Switch Is Regulated by the Oxytocin Receptor via KCC2

The enigma of the CLIC proteins: Ion channels, redox proteins, enzymes, scaffolding proteins?

The female epilepsy protein PCDH19 is a new GABAAR binding partner that regulates GABAergic transmission as well as migration and morphological maturation of hippocampal neurons.

The intracellular chloride ion channel protein CLIC1 undergoes a redox-controlled structural transition

The pathological prion protein forms ionic conductance in lipid bilayer

Toxic effects of expanded ataxin-1 involve mechanical instability of the nuclear membrane

USING ATOMIC FORCE MICROSCOPY TO INVESTIGATE PATCH-CLAMPED NUCLEAR MEMBRANE