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List of works by Jean A Boutin

4,4-Dimethyl-1,2,3,4-tetrahydroquinoline-based PPARalpha/gamma agonists. Part I: synthesis and pharmacological evaluation

scientific article published on 19 January 2008

8-Amino-5-nitro-6-phenoxyquinolines: potential non-peptidic neuropeptide Y receptor ligands.

scientific article

A Dimeric sesquiterpenoid from a Malaysian Meiogyne as a new inhibitor of Bcl-xL/BakBH3 domain peptide interaction

scientific article published in March 2009

A convenient 3-step synthesis of 3-acetamido-6-arylpyridazines directed to novel Y5 receptor antagonist

scientific article published on 01 May 2002

A generic approach for the purification of signaling complexes that specifically interact with the carboxyl-terminal domain of G protein-coupled receptors

scientific article published on 29 April 2008

A microplate assay for the screening of ADAMTS-4 inhibitors

scientific article

A potent and selective NPY Y5 antagonist reduces food intake but not through blockade of the NPY Y5 receptor

scientific article published on 01 April 2004

A quantitative assay for lysosomal acidification rates in human osteoclasts

scientific article published on 04 November 2010

A simple theoretical model for fluorescence polarization binding assay development

scientific article published on 7 November 2006

A structural study of the complex between neuroepithelial transforming gene 1 (Net1) and RhoA reveals a potential anti-cancer drug hotspot

scientific article published on 25 April 2018

A zinc chelator inhibiting gelatinases exerts potent in vitro anti-invasive effects ⬇️

scientific article published on June 19, 1998

Alternative Radioligands for Investigating the Molecular Pharmacology of Melatonin Receptors

scientific article published on 12 January 2016

Antimalarial Properties of Dunnione Derivatives as NQO2 Substrates

scientific article published on 15 October 2019

Antiparkinsonian agent piribedil displays antagonist properties at native, rat, and cloned, human alpha(2)-adrenoceptors: cellular and functional characterization

scientific article (publication date: June 2001)

Appetite-boosting property of pro-melanin-concentrating hormone(131-165) (neuropeptide-glutamic acid-isoleucine) is associated with proteolytic resistance.

scientific article published on August 2002

Approaches to some biochemical mechanisms of action of tuftsin and analogues

scientific article published on 01 May 1991

Assay of tyrosine protein kinase activity from HL-60 by high-performance liquid chromatography for specificity studies

scientific article published on 01 October 1990

Assessment of some tools for the characterization of the human osteoarthritic cartilage proteome

scientific article

Assessment of the Mulder and Van Doorn kinetic procedure and rapid centrifugal analysis of UDP-glucuronosyltransferase activities

article

Assessments of cellular melatonin receptor signaling pathways: β-arrestin recruitment, receptor internalization, and impedance variations.

scientific article published on 15 November 2017

Autotaxin is released from adipocytes, catalyzes lysophosphatidic acid synthesis, and activates preadipocyte proliferation. Up-regulated expression with adipocyte differentiation and obesity

scientific article published on 17 March 2003

Autotaxin.

scientific article published on 09 June 2009

Binding kinetics of glucose and allosteric activators to human glucokinase reveal multiple conformational states.

scientific article published on June 2009

Binding mode prediction and MD/MMPBSA-based free energy ranking for agonists of REV-ERBα/NCoR.

scientific article published on 15 July 2017

Binding of prostaglandins to human PPARgamma: tool assessment and new natural ligands

scientific article published in April 2001

Camphoroquinone reduction: another reaction catalyzed by rat liver cytosol 3 alpha-hydroxysteroid dehydrogenase

scientific article published on 01 April 1986

Cellular knock-down of quinone reductase 2: a laborious road to successful inhibition by RNA interference.

scientific article published on 15 July 2007

Characterization of 2-[125I]iodomelatonin binding sites in Syrian hamster peripheral organs

scientific article (publication date: July 1999)

Characterization of novel checkpoint kinase 1 inhibitors by in vitro assays and in human cancer cells treated with topoisomerase inhibitors.

scientific article

Characterization of the Mel1c melatoninergic receptor in platypus (Ornithorhynchus anatinus).

scientific article published on 12 March 2018

Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT1 and MT2 receptors

scientific article published on 29 December 2019

Chromatographic assay and peptide substrate characterization of partially purified farnesyl- and geranylgeranyltransferases from rat brain cytosol

scientific article published in June 1998

Combinatorial peptide libraries: robotic synthesis and analysis by nuclear magnetic resonance, mass spectrometry, tandem mass spectrometry, and high-performance capillary electrophoresis techniques.

scientific article published on February 1996

Combinatorial peptide synthesis: statistical evaluation of peptide distribution.

scientific article published on January 1996

Comment on "Obestatin, a peptide encoded by the ghrelin gene, opposes ghrelin's effects on food intake".

scientific article published in February 2007

Comparative analysis of melanin-concentrating hormone structure and activity in fishes and mammals

scientific article published on 01 October 2004

Comparative pharmacological studies of melatonin receptors: MT1, MT2 and MT3/QR2. Tissue distribution of MT3/QR2 .

scientific article published in June 2001

Constituents of Chamaecrista diphylla (L.) Greene Leaves with Potent Antioxidant Capacity: A Feature-Based Molecular Network Dereplication Approach

scientific article published on 10 May 2021

Cryo-electron microscopy and X-ray crystallography: complementary approaches to structural biology and drug discovery

scientific article

Cryo-microscopy, an alternative to the X-ray crystallography?

scientific article published on 12 September 2016

Crystallization via tubing microfluidics permits both in situ and ex situ X-ray diffraction

scientific article

Cytotoxic pentacyclic triterpenoids from Combretum sundaicum and Lantana camara as inhibitors of Bcl-xL/BakBH3 domain peptide interaction.

scientific article published in July 2009

Description of the constitutive activity of cloned human melatonin receptors hMT(1) and hMT(2) and discovery of inverse agonists

scientific article

Design and synthesis of 1-(2-alkanamidoethyl)-6-methoxy-7-azaindole derivatives as potent melatonin agonists

scientific article published on 26 February 2011

Design and synthesis of 3-phenyltetrahydronaphthalenic derivatives as new selective MT2 melatoninergic ligands. Part II.

scientific article published on 18 March 2009

Design and synthesis of benzofuranic derivatives as new ligands at the melatonin-binding site MT3.

scientific article published on 17 March 2008

Design and synthesis of indole and tetrahydroisoquinoline hydantoin derivatives as human chymase inhibitors

scientific article published in April 2004

Design and synthesis of naphthalenic derivatives as new ligands at the melatonin binding site MT3

scientific article published on 15 February 2011

Design and synthesis of naphthalenic dimers as selective MT1 melatoninergic ligands

scientific article published on March 2003

Design, Synthesis, Molecular Dynamics Simulation and Functional Evaluation of a Novel Series of 26RFa Peptide Analogues Containing a Mono- or Polyalkyl Guanidino Arginine Derivative

scientific article published on 07 November 2018

Design, synthesis and in vitro evaluation of novel benzo[b]thiophene derivatives as serotonin N-acetyltransferase (AANAT) inhibitors

scientific article published in April 2003

Design, synthesis and in vitro evaluation of novel derivatives as serotonin N-acetyltransferase inhibitors

scientific article published in December 2002

Design, synthesis and pharmacological evaluation of new series of naphthalenic analogues as melatoninergic (MT1/MT2) and serotoninergic 5-HT2C dual ligands (I).

scientific article published on 20 January 2012

Design, synthesis and pharmacological evaluation of novel naphthalenic derivatives as selective MT(1) melatoninergic ligands

scientific article

Detection of the human GPR50 orphan seven transmembrane protein by polyclonal antibodies mapping different epitopes.

scientific article

Detergent-free Isolation of Functional G Protein-Coupled Receptors into Nanometric Lipid Particles

scientific article published on 24 December 2015

Development of new assays and improved procedures for the purification of recombinant human chymase

scientific article published in November 2001

Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. I. A multivariate analysis of the binding profiles of 14 drugs at 21 native and cloned human receptor subtypes

scientific article (publication date: November 2002)

Differential actions of antiparkinson agents at multiple classes of monoaminergic receptor. II. Agonist and antagonist properties at subtypes of dopamine D(2)-like receptor and alpha(1)/alpha(2)-adrenoceptor

scientific article (publication date: November 2002)

Drug-induced hydrogen peroxide production in isolated rat hepatocytes

scientific article published on 01 February 1989

Effect of pretreatment with hydroxylated xenobiotics on the activities of rat liver UDP-glucuronosyl-transferases

scientific article published on 01 December 1983

Effects of EGIS-7625, a selective and competitive 5-HT2B receptor antagonist

scientific article

Effects of the new nitrosourea derivative, fotemustine, on the glutathione reductase activity in rat tissues in vivo and in isolated rat hepatocytes

scientific article published on 01 September 1989

Endothelin-1 inhibits TNF alpha-induced iNOS expression in 3T3-F442A adipocytes

scientific article published on July 2003

Expression and regulation of the nuclear receptor RORalpha in human vascular cells

scientific article published on 01 January 2002

Expression of UCP3 in CHO cells does not cause uncoupling, but controls mitochondrial activity in the presence of glucose

scientific article published in January 2006

Expression of the orphan GPR50 protein in rodent and human dorsomedial hypothalamus, tanycytes and median eminence

scientific article

Farnesyltransferase as target for non-cytotoxic anti-cancer agents: first steps

scientific article published in January 1991

Feature-Based Molecular Network-Guided Dereplication of Natural Bioactive Products from Leaves of Stryphnodendron pulcherrimum (Willd.) Hochr

scientific article published on 29 April 2021

Food intake regulation in rodents: Y5 or Y1 NPY receptors or both?

scientific article published on 01 February 2000

From peptide libraries to optimized nonpeptide ligands in the search for S-farnesyltransferase inhibitors.

scientific article

Functional characterization of human neuropeptide Y receptor subtype five specific antagonists using a luciferase reporter gene assay

scientific article

Functional invalidation of the autotaxin gene by a single amino acid mutation in mouse is lethal

scientific article published on 03 July 2007

Gene expression profiling during hibernation in the European hamster

scientific article published in Scientific Reports

General lack of structural characterization of chemically synthesized long peptides

scientific article published on 25 March 2019

Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA).

scientific article

Genomic organization and characterization of splice variants of the human histamine H3 receptor

article

Hamster Melatonin Receptors: Cloning and Binding Characterization of MT₁ and Attempt to Clone MT₂

scientific article published on 04 July 2018

Heterogeneity of hepatic UDP-Glucuronosyltransferase activities: Investigations of isoenzymes involved in p-nitrophenol glucuronidation

scientific article published on 01 September 1993

Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase activities

scientific article published on 01 July 1985

Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase(s) activities: a new kinetic approach for the study of induction and specificity

scientific article published in April 1994

Heterogeneity of hepatic microsomal UDP-glucuronosyltransferase(s) activities: comparison between human and mammalian species activities.

scientific article published in December 1984

Heterogeneity of hepatic microsomal UDP-glucuronosyltransferases activities: use and comparison of differential inductions in some mammalian species.

scientific article published in January 1987

High-capacity screening of arylalkylamine N-acetyltransferase inhibitors using a high-performance liquid chromatography system

scientific article published on 01 October 2000

High-throughput drug profiling with voltage- and calcium-sensitive fluorescent probes in human iPSC-derived cardiomyocytes.

scientific article published on 3 May 2016

High-throughput screening assay for new ligands at human melatonin receptors

scientific article published in December 2008

High-throughput screening for GPR119 modulators identifies a novel compound with anti-diabetic efficacy in db/db mice

scientific article

High-throughput screening of novel antagonists on melanin-concentrating hormone receptor-1.

scientific article

Highly Potent and Selective MT2 Melatonin Receptor Full Agonists from Conformational Analysis of 1-Benzyl-2-acylaminomethyl-tetrahydroquinolines

scientific article published on 3 September 2015

Image-free assessment of protein translocation in live cells.

scientific article published on 13 August 2009

In cellulo monitoring of quinone reductase activity and reactive oxygen species production during the redox cycling of 1,2 and 1,4 quinones

scientific article published on 16 September 2015

In vivo and in vitro glucuronidation of the flavonoid diosmetin in rats

scientific article published on 01 November 1993

In vivo characterisation of the human UCP3 gene minimal promoter in mice tibialis anterior muscles

scientific article published in November 2003

Inhibition of microsomal NAD(P)H oxidation by Triton X-100

scientific article published on 01 October 1986

Insights into the redox cycle of human quinone reductase 2

scientific article published on 09 August 2011

Integrated system for the screening of the specificity of protein kinase inhibitors

scientific article published on 01 August 1993

Investigation of S-farnesyl transferase substrate specificity with combinatorial tetrapeptide libraries.

scientific article

Journal of Pineal Research guideline for authors: Defining and characterizing melatonin targets

scientific article published on 17 December 2020

Kinetic, thermodynamic and X-ray structural insights into the interaction of melatonin and analogues with quinone reductase 2

scientific article

Ligand modulation of [35S]GTPgammaS binding at human alpha(2A), alpha(2B) and alpha(2C) adrenoceptors

scientific article

Limitations of the coupling of amino acid mixtures for the preparation of equimolar peptide libraries.

scientific article

Liquid chromatographic assay for the measurement of glucuronidation of arylcarboxylic acids using uridine diphospho-[U-14C]glucuronic acid

scientific article published on 01 November 1986

Loss of quinone reductase 2 function selectively facilitates learning behaviors

scientific journal article

MT3/QR2 melatonin binding site does not use melatonin as a substrate or a co-substrate

scientific article published on 23 September 2008

Melanin-concentrating hormone and its receptors: state of the art.

scientific article

Melatonergic ligands: Design, synthesis and pharmacological evaluation of novel series of naphthofuranic derivatives

scientific article published on 29 December 2015

Melatonin MT₁ and MT₂ receptors display different molecular pharmacologies only in the G-protein coupled state.

scientific article published on January 2014

Melatonin binding site MT3 is QR2: state of the art

scientific article published in January 2007

Melatonin controversies, an update

scientific article published on 27 October 2020

Melatonin from cerebrospinal fluid but not from blood reaches sheep cerebral tissues under physiological conditions

scientific article published in March 2014

Molecular Dynamics Simulations and Kinetic Measurements to Estimate and Predict Protein-Ligand Residence Times.

scientific article published on 8 July 2016

Molecular and cellular pharmacological properties of 5-methoxycarbonylamino-N-acetyltryptamine (MCA-NAT): a nonspecific MT3 ligand.

scientific article

Molecular basis of agonist docking in a human GPR103 homology model by site-directed mutagenesis and structure-activity relationship studies

scientific article published on 5 September 2014

Molecular cloning and pharmacological characterization of rat melatonin MT1 and MT2 receptors

scientific article

Molecular mechanisms of transcriptional control by Rev-erbα: An energetic foundation for reconciling structure and binding with biological function

scientific article published on 11 June 2015

Molecular pharmacology of NRH:quinone oxidoreductase 2: A detoxifying enzyme acting as an undercover toxifying enzyme

scientific article published on 10 September 2020

Molecular pharmacology of adipocyte-secreted autotaxin

scientific article

Molecular pharmacology of the mouse melatonin receptors MT₁ and MT₂.

scientific article

Molecular pharmacology of the ovine melatonin receptor: comparison with recombinant human MT1 and MT2 receptors

scientific article published in February 2004

Molecular tools to study melatonin pathways and actions.

scientific article

Murine and human autotaxin alpha, beta, and gamma isoforms: gene organization, tissue distribution, and biochemical characterization

scientific article published on 6 January 2008

Mutagenic analysis in a pure molecular system shows that thioredoxin‐interacting protein residue Cys247 is necessary and sufficient for a mixed disulfide formation with thioredoxin ⬇️

scientific article published on August 9, 2012

Myristoyl-CoA:protein N-myristoyltransferase activity in cancer cells. Purification and characterization of a cytosolic isoform from the murine leukemia cell line L1210.

scientific article published in June 1993

N-myristoyl-transferase activity in cancer cells. Solubilization, specificity and enzymatic inhibition of a N-myristoyl transferase from L1210 microsomes.

scientific article published on October 1991

NPY receptor subtypes involved in the contraction of the proximal colon of the rat.

scientific article published in September 1998

NRH:quinone reductase 2: an enzyme of surprises and mysteries

scientific article

New MT₂ Melatonin Receptor-Selective Ligands: Agonists and Partial Agonists

scientific article published on 23 June 2017

New alpha-amino phosphonic acid derivatives of vinblastine: chemistry and antitumor activity

scientific article published on 01 July 1991

New ligands at the melatonin binding site MT(3).

scientific article published on 18 January 2006

New melatonin (MT1/MT2) ligands: design and synthesis of (8,9-dihydro-7H-furo[3,2-f]chromen-1-yl) derivatives

scientific article published on 3 January 2014

New quinolinic derivatives as melatonergic ligands: Synthesis and pharmacological evaluation

scientific article published on 3 January 2017

New selective ligands of human cloned melatonin MT1 and MT2 receptors.

scientific article published on 23 May 2003

New substrate analogues of human serotonin N-acetyltransferase produce in situ specific and potent inhibitors

scientific article (publication date: 2004)

Novel 1,3-dicarbonyl compounds having 2(3H)-benzazolonic heterocycles as PPARgamma agonists

scientific article published on 02 August 2006

Old and new inhibitors of quinone reductase 2.

scientific article published on 04 May 2010

Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT3.

scientific article published in December 2004

Parallel synthesis and pharmacological screening of nonpeptide ligands of the neuropeptide Y receptor subtype Y5

scientific article published on 01 May 2001

Partial purification and characterization of a new p36/40 tyrosine protein kinase from HL-60.

scientific article published in May 1989

Peptide and nonpeptide lead discovery using robotically synthesized soluble libraries

scientific article published on June 1, 1997

Peripheral injections of melanin-concentrating hormone receptor 1 antagonist S38151 decrease food intake and body weight in rodent obesity models ⬇️

scientific article published on December 21, 2012

Pharmacological properties of a new alpha-aminophosphonic acid derivative of vinblastine

scientific article published in January 1990

Piceatannol and resveratrol share inhibitory effects on hydrogen peroxide release, monoamine oxidase and lipogenic activities in adipose tissue, but differ in their antilipolytic properties.

scientific article

Post-translational modification of Bid has differential effects on its susceptibility to cleavage by caspase 8 or caspase 3.

scientific article published on 21 February 2003

Preparation and pharmacological evaluation of a novel series of 2-(phenylthio)benzo[b]thiophenes as selective MT2 receptor ligands

scientific article published on 23 February 2011

Preparation of 4-azaindole and 7-azaindole dimers with a bisalkoxyalkyl spacer in order to preferentially target melatonin MT1 receptors over melatonin MT2 receptors

scientific article

Progress and new fields in molecular pharmacology

scientific article published on 31 August 2009

Purification and characterization of the major tyrosine protein kinase from the human promyelocytic cell line, HL60.

scientific article published in June 1993

Purification of the recombinant human serotonin N-acetyltransferase (EC 2.3.1.87): further characterization of and comparison with AANAT from other species

scientific article published in November 2004

Quinone reductase 2 as a promising target of melatonin therapeutic actions.

scientific article published on 14 October 2015

Quinone reductase 2 substrate specificity and inhibition pharmacology

scientific article published in February 2005

Rat liver microsomal 3 alpha-hydroxysteroid dehydrogenase and dihydrodiol dehydrogenase: solubilization, separation and partial purification

scientific article published in March 1986

Rational design of a low molecular weight, stable, potent, and long-lasting GPR103 aza-β3-pseudopeptide agonist

scientific article published on 17 August 2012

Receptor- and ligand-based study on novel 2,2'-bithienyl derivatives as non-peptidic AANAT inhibitors

scientific article

Recombinant human melatonin receptor MT1 isolated in mixed detergents shows pharmacology similar to that in mammalian cell membranes

scientific article (publication date: 2014)

Reduced food intake in response to CGP 71683A may be due to mechanisms other than NPY Y5 receptor blockade

scientific article published on 01 January 2001

Regulation of murine airway responsiveness by endothelial nitric oxide synthase

scientific article published in July 2001

Relationship between the cellular accumulation and the cytotoxicity of S12363, a new Vinca alkaloid derivative.

scientific article published on January 1992

Resistance to high-fat-diet-induced obesity and sexual dimorphism in the metabolic responses of transgenic mice with moderate uncoupling protein 3 overexpression in glycolytic skeletal muscles.

scientific article published on 4 August 2007

Role of Quinone Reductase 2 in the Antimalarial Properties of Indolone-Type Derivatives

scientific article published on 30 January 2017

S18327 (1-[2-[4-(6-fluoro-1, 2-benzisoxazol-3-yl)piperid-1-yl]ethyl]3-phenyl imidazolin-2-one), a novel, potential antipsychotic displaying marked antagonist properties at alpha(1)- and alpha(2)-adrenergic receptors: I. Receptorial, neurochemical, a

scientific article published on 01 January 2000

S18616, a highly potent, spiroimidazoline agonist at alpha(2)-adrenoceptors: I. Receptor profile, antinociceptive and hypothermic actions in comparison with dexmedetomidine and clonidine

scientific article published on 01 December 2000

S32212, a novel serotonin type 2C receptor inverse agonist/α2-adrenoceptor antagonist and potential antidepressant: I. A mechanistic characterization.

scientific article

S32826, a nanomolar inhibitor of autotaxin: discovery, synthesis and applications as a pharmacological tool.

scientific article published on 28 August 2008

S33138 [N-[4-[2-[(3aS,9bR)-8-cyano-1,3a,4,9b-tetrahydro[1]-benzopyrano[3,4-c]pyrrol-2(3H)-yl)-ethyl]phenylacetamide], a preferential dopamine D3 versus D2 receptor antagonist and potential antipsychotic agent: I. Receptor-binding profile and functio

scientific article published on 16 November 2007

S38151 [p-guanidinobenzoyl-[Des-Gly(10)]-MCH(7-17)] is a potent and selective antagonist at the MCH(1) receptor and has anti-feeding properties in vivo

scientific article published on 18 July 2009

S49076 is a novel kinase inhibitor of MET, AXL, and FGFR with strong preclinical activity alone and in association with bevacizumab

scientific article published on 26 June 2013

SLC-1 receptor mediates effect of melanin-concentrating hormone on feeding behavior in rat: a structure-activity study.

scientific article

Screening of ligand binding on melatonin receptor using non-peptide combinatorial libraries.

scientific article

Screening of protein kinase inhibitors identifies PKC inhibitors as inhibitors of osteoclastic acid secretion and bone resorption.

scientific article

Screening ubiquitin specific protease activities using chemically synthesized ubiquitin and ubiquitinated peptides

scientific article published on 16 December 2016

Secure and Sustainable Sourcing of Plant Tissues for the Exhaustive Exploration of Their Chemodiversity

scientific article published on 18 December 2020

Selection of a histidine-containing inhibitor of gelatinases through deconvolution of combinatorial tetrapeptide libraries ⬇️

scientific article published on January 1, 1997

Specific oncogenic activity of the Src-family tyrosine kinase c-Yes in colon carcinoma cells

scientific article

Structure and expression of the human histamine H4-receptor gene.

scientific article published in June 2001

Structure-activity relationships of a series of analogues of the RFamide-related peptide 26RFa.

scientific article published on 9 June 2011

Studies of UDP-glucuronosyltransferase activity toward eugenol, using a gas chromatographic method of measurement

article

Studies of the melatonin binding site location onto quinone reductase 2 by directed mutagenesis.

scientific article published on 11 May 2008

Studies of the potency of protein kinase inhibitors on ATPase activities

scientific article published in January 1993

Substrate phosphorylation capacities of the major tyrosine protein kinase from the human promyelocytic cell line, HL-60.

scientific article

Substrate specificity and inhibition studies of human serotonin N-acetyltransferase

scientific article (publication date: 24 March 2000)

Synthesis and pharmacological evaluation of a series of the agomelatine analogues as melatonin MT1 /MT2 agonist and 5-HT2C antagonist

scientific article published on 12 September 2013

Synthesis and pharmacological evaluation of dual ligands for melatonin (MT1/MT2) and serotonin 5-HT2C receptor subtypes (II).

scientific article published on 13 December 2014

Synthesis and pharmacological evaluation of thieno[2,3-b]pyridine derivatives as novel c-Src inhibitors.

scientific article published on 13 March 2011

Synthesis and structure-affinity-activity relationships of novel benzofuran derivatives as MT(2) melatonin receptor selective ligands

scientific article

Synthesis of 3-phenylnaphthalenic derivatives as new selective MT(2) melatoninergic ligands.

scientific article published on 27 August 2008

Synthesis of 5-substituted-2,3-dihydro-1,4-benzoxathiins: biological evaluation as melatonin receptors ligands

scientific article published in April 2003

Synthesis of a small library of phenylalkylamide derivatives as melatoninergic ligands for human mt1 and MT2 receptors.

scientific article

Synthesis of new 8(S)-HETE analogs and their biological evaluation as activators of the PPAR nuclear receptors

scientific article published in October 2010

Synthesis of new arylalkoxy amido derivatives as melatoninergic ligands

scientific article published in March 2003

Synthesis of new carbo- and heterocyclic analogues of 8-HETE and evaluation of their activity towards the PPARs

scientific article published in October 2005

Synthesis of nitroindole derivatives with high affinity and selectivity for melatoninergic binding sites MT(3).

scientific article

Synthesis of potential Rho-kinase inhibitors based on the chemistry of an original heterocycle: 4,4-dimethyl-3,4-dihydro-1H-quinolin-2-one

scientific article published on 23 November 2007

The PINK1 kinase-driven ubiquitin ligase Parkin promotes mitochondrial protein import through the presequence pathway in living cells

scientific article published on 14 August 2019

The RFamide neuropeptide 26RFa and its role in the control of neuroendocrine functions.

scientific article published on 20 April 2011

The active conformation of human glucokinase is not altered by allosteric activators

scientific article

The end of a myth: cloning and characterization of the ovine melatonin MT(2) receptor.

scientific article published on 08 October 2009

The five dimensions of receptor pharmacology exemplified by melatonin receptors: An opinion

scientific article published on 29 December 2019

The role of the matrix metalloproteinases during in vitro vessel formation

scientific journal article

Therapeutic perspectives for melatonin agonists and antagonists.

scientific article

Therapeutic potential of melatonin ligands.

scientific article

Truncated isoforms inhibit [3H]prazosin binding and cellular trafficking of native human α1A-adrenoceptors

scientific article published in 1999

Tyrosine protein kinase inhibition and cancer.

scientific article published on October 1994

UDP-glucuronosyltransferase activities in human liver microsomes and in some laboratory animal species

article

UDP-glucuronosyltransferase(S) activities towards natural substrates in rat liver microsomes. Kinetic properties and influence of Triton X-100 activation

article

Uncoupling protein-3 (UCP3) mRNA expression in reconstituted human muscle after myoblast transplantation in RAG2-/-/gamma c/C5(-) immunodeficient mice

scientific article published on 25 September 2002

Use of hydrophilic interaction chromatography for the study of tyrosine protein kinase specificity

scientific article published on 01 December 1992

Use of the main tyrosine protein kinase activity purified from HL-60 in the search for a new class of anticancer compounds

scientific article

VHH characterization. Comparison of recombinant with chemically synthesized anti-HER2 VHH

scientific article published on 29 August 2019

W2476 ameliorates β-cell dysfunction and exerts therapeutic effects in mouse models of diabetes via modulation of the thioredoxin-interacting protein signaling pathway.

scientific article published on 15 May 2017

[UDP-glucuronosyltransferases and glucuronoconjugation]

scientific article published on 01 May 1985

¹⁹F nuclear magnetic resonance screening of glucokinase activators.

scientific article published on 12 February 2015

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